ES2264182T3 - Proceso enzimatico para la preparacion de (s)-cian-hidrinas. - Google Patents

Proceso enzimatico para la preparacion de (s)-cian-hidrinas.

Info

Publication number
ES2264182T3
ES2264182T3 ES98124003T ES98124003T ES2264182T3 ES 2264182 T3 ES2264182 T3 ES 2264182T3 ES 98124003 T ES98124003 T ES 98124003T ES 98124003 T ES98124003 T ES 98124003T ES 2264182 T3 ES2264182 T3 ES 2264182T3
Authority
ES
Spain
Prior art keywords
reaction
hydroxynitrilase
process according
aldehyde
stirred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98124003T
Other languages
English (en)
Spanish (es)
Inventor
Peter Pochlauer
Michael Schmidt
Irma Wirth
Rudolf Neuhofer
Antonia A. Zabelinskaja-Mackova
Herfried Griengl
Cor Van Den Broek
Raf W.E.G. Reintjens
Herman Jelle Wories
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
DSM Fine Chemicals Austria Nfg GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3529691&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2264182(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM Fine Chemicals Austria Nfg GmbH and Co KG filed Critical DSM Fine Chemicals Austria Nfg GmbH and Co KG
Application granted granted Critical
Publication of ES2264182T3 publication Critical patent/ES2264182T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
ES98124003T 1997-12-29 1998-12-17 Proceso enzimatico para la preparacion de (s)-cian-hidrinas. Expired - Lifetime ES2264182T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0219297A AT406961B (de) 1997-12-29 1997-12-29 Enzymatisches verfahren zur herstellung von (s)-cyanhydrinen
AT2192/97 1997-12-29

Publications (1)

Publication Number Publication Date
ES2264182T3 true ES2264182T3 (es) 2006-12-16

Family

ID=3529691

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98124003T Expired - Lifetime ES2264182T3 (es) 1997-12-29 1998-12-17 Proceso enzimatico para la preparacion de (s)-cian-hidrinas.

Country Status (8)

Country Link
US (1) US6225095B1 (enExample)
EP (1) EP0927766B1 (enExample)
JP (1) JP4372254B2 (enExample)
AT (1) AT406961B (enExample)
CA (1) CA2257562C (enExample)
DE (1) DE59813598D1 (enExample)
DK (1) DK0927766T3 (enExample)
ES (1) ES2264182T3 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408231B (de) * 1999-12-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von optisch aktiven cyanhydrinen unter verwendung von r-oxynitrilase
DE19963485B4 (de) 1999-12-28 2006-02-16 JFC - Jülich Fine Chemicals GmbH Verfahren zur Herstellung von Hydroxylnitril-Lyasen
US7078225B2 (en) 2000-06-02 2006-07-18 Nippon Shokubai Co., Ltd. Method for enzymatically producing an optically active cyanohydrin
JP2002142792A (ja) 2000-11-01 2002-05-21 Clariant Gmbh 光学活性シアノヒドリンおよび二次生成物の製造法
EP1223220B1 (de) 2001-01-16 2006-03-01 DSM Fine Chemicals Austria Nfg GmbH & Co KG Gene, enthaltend eine für Hydroxynitrillyase codierende DNA-Sequenz, rekombinante Proteine mit Hydroxynitrillyase-Aktivität und deren Verwendung
AT411064B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von enantiomerenangereicherten cyanhydrinen unter verwendung von acetalen oder ketalen als substrate
AT411065B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von heterocyclischen (r)- und (s)-cyanhydrinen
AT410792B (de) * 2001-12-28 2003-07-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von geschützten, enantiomeren-angereicherten cyanhydrinen durch in-situ-derivatisierung
DE102005007174A1 (de) * 2005-02-16 2006-08-24 Cognis Ip Management Gmbh Verwendung von PIT-Emulsionen in biokatalytischen Reaktionen
WO2008071695A1 (en) 2006-12-14 2008-06-19 Dsm Ip Assets Bv R-hnl random variants and their use for preparing optically pure, sterically hindered cyanohydrins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3701383A1 (de) * 1987-01-20 1988-07-28 Degussa Verfahren zur herstellung von optisch aktiven cyanhydrinen
AT396252B (de) * 1991-10-31 1993-07-26 Chemie Linz Gmbh Enzymatisches verfahren zur enantioselektiven herstellung optisch aktiver cyanhydrine
EP0547655A1 (en) * 1991-12-11 1993-06-23 Duphar International Research B.V Method of preparing optically active cyanohydrins
AT400035B (de) * 1993-06-01 1995-09-25 Chemie Linz Gmbh Enzymatisches verfahren zur herstellung aliphatischer s-cyanhydrine

Also Published As

Publication number Publication date
JP4372254B2 (ja) 2009-11-25
US6225095B1 (en) 2001-05-01
ATA219297A (de) 2000-03-15
CA2257562A1 (en) 1999-06-29
JPH11243983A (ja) 1999-09-14
CA2257562C (en) 2007-12-04
AT406961B (de) 2000-11-27
EP0927766A1 (de) 1999-07-07
DE59813598D1 (de) 2006-07-27
EP0927766B1 (de) 2006-06-14
DK0927766T3 (da) 2006-09-04

Similar Documents

Publication Publication Date Title
CA1335269C (en) Enzymatic process for the preparation of optically active cyanohydrins
ES2264182T3 (es) Proceso enzimatico para la preparacion de (s)-cian-hidrinas.
JP3253150B2 (ja) 光学的に活性なシアノヒドリン類の製造方法
JP3174171B2 (ja) 光学的に活性なシアノヒドリンのエナンチオ選択的、酵素による製造方法
JP3117157B2 (ja) 固定化酵素によるアルコールのアシル化方法
ES2281675T5 (es) Procedimiento para producir un ester (4E)-5-cloro-2-isopropil-4-pentenoato y un isómero ópticamente activo de este ester
CA2277916C (en) Enzymatic processes for the preparation of (s)-cyanohydrins
US5714356A (en) Enzymic process for preparing aliphatic S-cyanohydrins
EP1026256B1 (en) Method for the production of optically active cyanohydrins
ES2211662T3 (es) Procedimiento para la produccion de cianohidrinas activas opticamente utilizando r-oxinitrilasa.
ES2328279T3 (es) Reduccion asimetrica de 1,1,1-trifluoroacetona.
EP1116789B1 (en) Immobilised enzyme and method for synthesizing an optically active cyanohydrin
JP4995429B2 (ja) マンデル酸類の精製方法
KR0180867B1 (ko) 비용매상 2-페닐에탄올계 에스테르 화합물의 제조방법
JP4196470B2 (ja) 光学活性α−ヒドロキシラクトン類の製造方法
JP2006000006A (ja) 光学活性２−アルキル−ｄ−システインエステルの製造方法
RO108252B1 (ro) Procedeu enzimatic, de separare a acidului D-(-)-a-aminofenilacetic din racemic