JP4372254B2 - 酵素による（ｓ）−シアノヒドリンの製造方法 - Google Patents

酵素による（ｓ）−シアノヒドリンの製造方法 Download PDF

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Publication number
JP4372254B2
JP4372254B2 JP37339298A JP37339298A JP4372254B2 JP 4372254 B2 JP4372254 B2 JP 4372254B2 JP 37339298 A JP37339298 A JP 37339298A JP 37339298 A JP37339298 A JP 37339298A JP 4372254 B2 JP4372254 B2 JP 4372254B2
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Japan
Prior art keywords
reaction
hydroxynitrile
lyase
cyanohydrin
aldehyde
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Expired - Fee Related
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JP37339298A
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English (en)
Japanese (ja)
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JPH11243983A (ja
JPH11243983A5 (enExample
Inventor
ペーター・ペヒラウエル
ミヒヤエル・シユミット
イルマ・ヴイルト
ルードルフ・ノイホーフエル
マッコーヴァ アントニア・ツアベリンスカヤ−
ヘルフリート・グリーングル
コル・ヴアン・デン・ブレク
ラフ・ライントイエンス
ヘルマン・イエレ・ヴオリース
Original Assignee
デーエスエム・ファイン・ケミカルズ・オーストリア・ナッハフォルゲル・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト
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Application filed by デーエスエム・ファイン・ケミカルズ・オーストリア・ナッハフォルゲル・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト filed Critical デーエスエム・ファイン・ケミカルズ・オーストリア・ナッハフォルゲル・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト
Publication of JPH11243983A publication Critical patent/JPH11243983A/ja
Publication of JPH11243983A5 publication Critical patent/JPH11243983A5/ja
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Publication of JP4372254B2 publication Critical patent/JP4372254B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP37339298A 1997-12-29 1998-12-28 酵素による（ｓ）−シアノヒドリンの製造方法 Expired - Fee Related JP4372254B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0219297A AT406961B (de) 1997-12-29 1997-12-29 Enzymatisches verfahren zur herstellung von (s)-cyanhydrinen
AT2192/97 1997-12-29

Publications (3)

Publication Number Publication Date
JPH11243983A JPH11243983A (ja) 1999-09-14
JPH11243983A5 JPH11243983A5 (enExample) 2006-01-12
JP4372254B2 true JP4372254B2 (ja) 2009-11-25

Family

ID=3529691

Family Applications (1)

Application Number Title Priority Date Filing Date
JP37339298A Expired - Fee Related JP4372254B2 (ja) 1997-12-29 1998-12-28 酵素による（ｓ）−シアノヒドリンの製造方法

Country Status (8)

Country Link
US (1) US6225095B1 (enExample)
EP (1) EP0927766B1 (enExample)
JP (1) JP4372254B2 (enExample)
AT (1) AT406961B (enExample)
CA (1) CA2257562C (enExample)
DE (1) DE59813598D1 (enExample)
DK (1) DK0927766T3 (enExample)
ES (1) ES2264182T3 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408231B (de) * 1999-12-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von optisch aktiven cyanhydrinen unter verwendung von r-oxynitrilase
DE19963485B4 (de) 1999-12-28 2006-02-16 JFC - Jülich Fine Chemicals GmbH Verfahren zur Herstellung von Hydroxylnitril-Lyasen
US7078225B2 (en) 2000-06-02 2006-07-18 Nippon Shokubai Co., Ltd. Method for enzymatically producing an optically active cyanohydrin
JP2002142792A (ja) 2000-11-01 2002-05-21 Clariant Gmbh 光学活性シアノヒドリンおよび二次生成物の製造法
EP1223220B1 (de) 2001-01-16 2006-03-01 DSM Fine Chemicals Austria Nfg GmbH & Co KG Gene, enthaltend eine für Hydroxynitrillyase codierende DNA-Sequenz, rekombinante Proteine mit Hydroxynitrillyase-Aktivität und deren Verwendung
AT411064B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von enantiomerenangereicherten cyanhydrinen unter verwendung von acetalen oder ketalen als substrate
AT411065B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von heterocyclischen (r)- und (s)-cyanhydrinen
AT410792B (de) * 2001-12-28 2003-07-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von geschützten, enantiomeren-angereicherten cyanhydrinen durch in-situ-derivatisierung
DE102005007174A1 (de) * 2005-02-16 2006-08-24 Cognis Ip Management Gmbh Verwendung von PIT-Emulsionen in biokatalytischen Reaktionen
WO2008071695A1 (en) 2006-12-14 2008-06-19 Dsm Ip Assets Bv R-hnl random variants and their use for preparing optically pure, sterically hindered cyanohydrins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3701383A1 (de) * 1987-01-20 1988-07-28 Degussa Verfahren zur herstellung von optisch aktiven cyanhydrinen
AT396252B (de) * 1991-10-31 1993-07-26 Chemie Linz Gmbh Enzymatisches verfahren zur enantioselektiven herstellung optisch aktiver cyanhydrine
EP0547655A1 (en) * 1991-12-11 1993-06-23 Duphar International Research B.V Method of preparing optically active cyanohydrins
AT400035B (de) * 1993-06-01 1995-09-25 Chemie Linz Gmbh Enzymatisches verfahren zur herstellung aliphatischer s-cyanhydrine

Also Published As

Publication number Publication date
US6225095B1 (en) 2001-05-01
ATA219297A (de) 2000-03-15
CA2257562A1 (en) 1999-06-29
JPH11243983A (ja) 1999-09-14
CA2257562C (en) 2007-12-04
AT406961B (de) 2000-11-27
EP0927766A1 (de) 1999-07-07
ES2264182T3 (es) 2006-12-16
DE59813598D1 (de) 2006-07-27
EP0927766B1 (de) 2006-06-14
DK0927766T3 (da) 2006-09-04

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