ES2258280T3 - Nueva proteina de union a fibrinogeno originada a partir de staphylococus coagulasa negativo. - Google Patents
Nueva proteina de union a fibrinogeno originada a partir de staphylococus coagulasa negativo.Info
- Publication number
- ES2258280T3 ES2258280T3 ES97928617T ES97928617T ES2258280T3 ES 2258280 T3 ES2258280 T3 ES 2258280T3 ES 97928617 T ES97928617 T ES 97928617T ES 97928617 T ES97928617 T ES 97928617T ES 2258280 T3 ES2258280 T3 ES 2258280T3
- Authority
- ES
- Spain
- Prior art keywords
- protein
- baselineskip
- fibrinogen
- polypeptide
- fibrinogen binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 230000028993 immune response Effects 0.000 description 1
- 239000003022 immunostimulating agent Substances 0.000 description 1
- 230000003308 immunostimulating effect Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000004255 ion exchange chromatography Methods 0.000 description 1
- BPHPUYQFMNQIOC-NXRLNHOXSA-N isopropyl beta-D-thiogalactopyranoside Chemical compound CC(C)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O BPHPUYQFMNQIOC-NXRLNHOXSA-N 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 210000004897 n-terminal region Anatomy 0.000 description 1
- 238000004091 panning Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 206010034674 peritonitis Diseases 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000000163 radioactive labelling Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000012723 sample buffer Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 229940115920 streptococcus dysgalactiae Drugs 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000000304 virulence factor Substances 0.000 description 1
- 230000007923 virulence factor Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9602496 | 1996-06-20 | ||
| SE9602496A SE9602496D0 (sv) | 1996-06-20 | 1996-06-20 | Method and means for producing a fibrinogen binding protein and its use in biotechnology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2258280T3 true ES2258280T3 (es) | 2006-08-16 |
Family
ID=20403140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97928617T Expired - Lifetime ES2258280T3 (es) | 1996-06-20 | 1997-06-18 | Nueva proteina de union a fibrinogeno originada a partir de staphylococus coagulasa negativo. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6733758B1 (enExample) |
| EP (1) | EP0922056B1 (enExample) |
| JP (1) | JP4173549B2 (enExample) |
| AT (1) | ATE316979T1 (enExample) |
| AU (1) | AU3282597A (enExample) |
| CA (1) | CA2294433A1 (enExample) |
| DE (1) | DE69735207T2 (enExample) |
| ES (1) | ES2258280T3 (enExample) |
| SE (1) | SE9602496D0 (enExample) |
| WO (1) | WO1997048727A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6685943B1 (en) | 1997-01-21 | 2004-02-03 | The Texas A&M University System | Fibronectin binding protein compositions and methods of use |
| US6380370B1 (en) * | 1997-08-14 | 2002-04-30 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| AU1537699A (en) * | 1997-11-26 | 1999-06-15 | Bioresearch Ireland a division of Eolas - The Irish Science and Technology Agency | Extracellular matrix-binding proteins from (staphylococcus aureus) |
| WO2000012131A1 (en) * | 1998-08-31 | 2000-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US6635473B1 (en) * | 1998-08-31 | 2003-10-21 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Polypeptides and polynucleotides from coagulase-negative staphylococci |
| CA2341177A1 (en) * | 1998-08-31 | 2000-03-09 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| US6692739B1 (en) | 1998-08-31 | 2004-02-17 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| US6703025B1 (en) | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US20040038327A1 (en) * | 1999-08-31 | 2004-02-26 | Foster Timothy J. | Antibodies to polypeptides from coagulase-negative staphylococci |
| EP2320233A1 (en) | 2001-06-15 | 2011-05-11 | Inhibitex, Inc. | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
| CA2478029A1 (en) * | 2002-03-05 | 2003-09-18 | Inhibitex, Inc. | Monoclonal and polyclonal antibodies recognizing coagulase-negative staphylococcal proteins |
| CA2517439C (en) | 2003-03-07 | 2013-07-23 | Wyeth Holdings Corporation | Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| ES2730275T3 (es) | 2004-09-22 | 2019-11-11 | Glaxosmithkline Biologicals Sa | Composición inmunógena para uso en vacunación contra estafilococos |
| KR101541383B1 (ko) | 2006-03-30 | 2015-08-03 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 면역원성 조성물 |
| WO2007127339A2 (en) * | 2006-04-26 | 2007-11-08 | Tyco Healthcare Group Lp | Multi-stage microporation device |
| SI2445522T1 (sl) | 2009-06-22 | 2017-10-30 | Wyeth Llc | Imunogeni sestavki antigenov Staphylococcusa aureusa |
| CA2768204A1 (en) | 2009-07-15 | 2011-01-20 | Aimm Therapeutics B.V. | Gram-positive bacteria specific binding compounds |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| KR20230031322A (ko) | 2020-06-27 | 2023-03-07 | 크레센타 바이오사이언시즈 | 세포 물질대사를 조정하는 화합물의 조성물 및 사용 방법 |
| US12138243B2 (en) | 2021-12-31 | 2024-11-12 | Crescenta Biosciences | Antiviral use of FABP4 modulating compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3583987D1 (de) | 1984-11-06 | 1991-10-10 | Thomae Gmbh Dr K | Antibiotisches polypeptid, verfahren zu seiner herstellung und seine verwendung. |
| ATE95187T1 (de) * | 1988-07-15 | 1993-10-15 | Thomae Gmbh Dr K | Verfahren zur gewinnung, isolierung und reinigung von epidermin. |
| US5055455A (en) * | 1988-09-28 | 1991-10-08 | Brigham And Women's Hospital | Capsular polysaccharide adhesin antigen, preparation, purification and use |
| US5571511A (en) * | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
| EP0621875B1 (en) * | 1992-09-21 | 2002-03-27 | Alfa-Laval Agri International Ab | Fibrinogen binding protein |
| IL109410A0 (en) * | 1993-04-30 | 1994-07-31 | Ell Lilly & Company | Fema gene of staphylococcus epidermidis, fema protein, and vectors and microorganisms comprising the fema gene |
| US6107068A (en) * | 1995-12-22 | 2000-08-22 | The University Of British Columbia | Coenzyme A disulfide reductase, and inhibitors thereof useful as antimicrobial agents |
-
1996
- 1996-06-20 SE SE9602496A patent/SE9602496D0/xx unknown
-
1997
- 1997-06-18 EP EP97928617A patent/EP0922056B1/en not_active Expired - Lifetime
- 1997-06-18 WO PCT/SE1997/001091 patent/WO1997048727A1/en not_active Ceased
- 1997-06-18 JP JP50281998A patent/JP4173549B2/ja not_active Expired - Fee Related
- 1997-06-18 CA CA002294433A patent/CA2294433A1/en not_active Abandoned
- 1997-06-18 DE DE69735207T patent/DE69735207T2/de not_active Expired - Fee Related
- 1997-06-18 AT AT97928617T patent/ATE316979T1/de not_active IP Right Cessation
- 1997-06-18 US US09/147,405 patent/US6733758B1/en not_active Expired - Lifetime
- 1997-06-18 ES ES97928617T patent/ES2258280T3/es not_active Expired - Lifetime
- 1997-06-18 AU AU32825/97A patent/AU3282597A/en not_active Abandoned
-
2004
- 2004-03-23 US US10/806,288 patent/US7160990B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE316979T1 (de) | 2006-02-15 |
| CA2294433A1 (en) | 1997-12-24 |
| SE9602496D0 (sv) | 1996-06-20 |
| JP2001503609A (ja) | 2001-03-21 |
| DE69735207T2 (de) | 2006-11-02 |
| JP4173549B2 (ja) | 2008-10-29 |
| US20040209326A1 (en) | 2004-10-21 |
| WO1997048727A1 (en) | 1997-12-24 |
| EP0922056B1 (en) | 2006-02-01 |
| AU3282597A (en) | 1998-01-07 |
| US7160990B2 (en) | 2007-01-09 |
| US6733758B1 (en) | 2004-05-11 |
| EP0922056A1 (en) | 1999-06-16 |
| DE69735207D1 (de) | 2006-04-13 |
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