ES2236566T3 - Antimicotico. - Google Patents
Antimicotico.Info
- Publication number
- ES2236566T3 ES2236566T3 ES02762280T ES02762280T ES2236566T3 ES 2236566 T3 ES2236566 T3 ES 2236566T3 ES 02762280 T ES02762280 T ES 02762280T ES 02762280 T ES02762280 T ES 02762280T ES 2236566 T3 ES2236566 T3 ES 2236566T3
- Authority
- ES
- Spain
- Prior art keywords
- metal salt
- formula
- diseases
- copper
- active substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001857 anti-mycotic effect Effects 0.000 title 1
- 239000002543 antimycotic Substances 0.000 title 1
- 229910052751 metal Inorganic materials 0.000 claims abstract description 21
- 239000002184 metal Substances 0.000 claims abstract description 21
- 150000003839 salts Chemical class 0.000 claims abstract description 20
- 125000003118 aryl group Chemical group 0.000 claims abstract description 6
- 125000002091 cationic group Chemical group 0.000 claims abstract description 6
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims abstract description 4
- 239000003814 drug Substances 0.000 claims abstract description 4
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 13
- 150000001875 compounds Chemical class 0.000 claims description 12
- 201000010099 disease Diseases 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 10
- 150000001768 cations Chemical class 0.000 claims description 7
- AAGBSENFWIPBPN-UHFFFAOYSA-N N=[N+](OO[Cu]OO[N+](=N)C1CCCCC1)C1CCCCC1 Chemical compound N=[N+](OO[Cu]OO[N+](=N)C1CCCCC1)C1CCCCC1 AAGBSENFWIPBPN-UHFFFAOYSA-N 0.000 claims description 6
- 239000000654 additive Substances 0.000 claims description 5
- 239000008177 pharmaceutical agent Substances 0.000 claims description 5
- 230000001225 therapeutic effect Effects 0.000 claims description 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical group [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- 230000000996 additive effect Effects 0.000 claims description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 2
- VMQMZMRVKUZKQL-UHFFFAOYSA-N Cu+ Chemical compound [Cu+] VMQMZMRVKUZKQL-UHFFFAOYSA-N 0.000 claims 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 1
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- 239000010941 cobalt Substances 0.000 claims 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims 1
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- 229910052725 zinc Inorganic materials 0.000 claims 1
- 239000011701 zinc Substances 0.000 claims 1
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- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 description 2
- 125000000753 cycloalkyl group Chemical group 0.000 description 2
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- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
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- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
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- 239000002023 wood Substances 0.000 description 2
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
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- 125000005918 1,2-dimethylbutyl group Chemical group 0.000 description 1
- 125000006218 1-ethylbutyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000006176 2-ethylbutyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(C([H])([H])*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000004493 2-methylbut-1-yl group Chemical group CC(C*)CC 0.000 description 1
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- 125000005917 3-methylpentyl group Chemical group 0.000 description 1
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- 239000000312 peanut oil Substances 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 125000003538 pentan-3-yl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000011814 protection agent Substances 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000012177 spermaceti Substances 0.000 description 1
- 229940084106 spermaceti Drugs 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000001973 tert-pentyl group Chemical group [H]C([H])([H])C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 230000007332 vesicle formation Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10127244 | 2001-06-05 | ||
| DE10127244 | 2001-06-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2236566T3 true ES2236566T3 (es) | 2005-07-16 |
Family
ID=7687241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02762280T Expired - Lifetime ES2236566T3 (es) | 2001-06-05 | 2002-06-04 | Antimicotico. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050070509A1 (enExample) |
| EP (1) | EP1399164B1 (enExample) |
| JP (1) | JP2005501008A (enExample) |
| AT (1) | ATE287716T1 (enExample) |
| CA (1) | CA2448040A1 (enExample) |
| DE (1) | DE50202121D1 (enExample) |
| ES (1) | ES2236566T3 (enExample) |
| WO (1) | WO2002098430A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0326284D0 (en) * | 2003-11-11 | 2003-12-17 | Basf Ag | Microbicidal compositions and their use |
| JP4540331B2 (ja) * | 2003-12-16 | 2010-09-08 | 三愛石油株式会社 | 新規防藻剤 |
| JP2007522135A (ja) * | 2004-01-30 | 2007-08-09 | ザ ジョンズ ホプキンス ユニバーシティ | ニトロキシル前駆化合物および使用方法 |
| GB0718440D0 (en) * | 2007-09-21 | 2007-10-31 | Reckitt Benckiser Uk Ltd | Hard surface treatment compositions with improved mold fungi remediation properties |
| RU2714320C1 (ru) * | 2019-05-14 | 2020-02-14 | Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук | Способ получения n,o-комплексов { 2-[(диметиламино)метил]фенол} диацетат меди(ii), обладающих фунгицидной активностью в отношении candida albicans |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE362207B (enExample) * | 1968-12-31 | 1973-12-03 | Basf Ag | |
| DE2410603C2 (de) * | 1974-03-06 | 1982-12-23 | Basf Ag, 6700 Ludwigshafen | Fungizid für den Holzschutz |
| DE2633452A1 (de) * | 1976-07-24 | 1978-01-26 | Basf Ag | Triorganozinnverbindungen von hydroxydiazeniumoxiden |
| AR001812A1 (es) * | 1996-04-24 | 1997-12-10 | Nunez Omar Cristian | Producto ectoparasiticida antimicotico de uso externo |
-
2002
- 2002-06-04 ES ES02762280T patent/ES2236566T3/es not_active Expired - Lifetime
- 2002-06-04 AT AT02762280T patent/ATE287716T1/de not_active IP Right Cessation
- 2002-06-04 EP EP02762280A patent/EP1399164B1/de not_active Expired - Lifetime
- 2002-06-04 WO PCT/EP2002/006128 patent/WO2002098430A1/de not_active Ceased
- 2002-06-04 DE DE50202121T patent/DE50202121D1/de not_active Expired - Fee Related
- 2002-06-04 JP JP2003501469A patent/JP2005501008A/ja not_active Withdrawn
- 2002-06-04 CA CA002448040A patent/CA2448040A1/en not_active Abandoned
- 2002-06-04 US US10/479,624 patent/US20050070509A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050070509A1 (en) | 2005-03-31 |
| EP1399164A1 (de) | 2004-03-24 |
| WO2002098430A1 (de) | 2002-12-12 |
| ATE287716T1 (de) | 2005-02-15 |
| CA2448040A1 (en) | 2002-12-12 |
| EP1399164B1 (de) | 2005-01-26 |
| JP2005501008A (ja) | 2005-01-13 |
| DE50202121D1 (de) | 2005-03-03 |
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