ES2231281T3 - Vectores competentes de replicacion anticancerosos. - Google Patents
Vectores competentes de replicacion anticancerosos.Info
- Publication number
- ES2231281T3 ES2231281T3 ES00975153T ES00975153T ES2231281T3 ES 2231281 T3 ES2231281 T3 ES 2231281T3 ES 00975153 T ES00975153 T ES 00975153T ES 00975153 T ES00975153 T ES 00975153T ES 2231281 T3 ES2231281 T3 ES 2231281T3
- Authority
- ES
- Spain
- Prior art keywords
- cells
- cell
- adp
- replication
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US351778 | 1999-07-12 | ||
| US09/351,778 US7589069B1 (en) | 1999-07-12 | 1999-07-12 | Replication-competent anti-cancer vectors |
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| ES2231281T3 true ES2231281T3 (es) | 2005-05-16 |
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| ES00975153T Expired - Lifetime ES2231281T3 (es) | 1999-07-12 | 2000-07-12 | Vectores competentes de replicacion anticancerosos. |
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| US (3) | US7589069B1 (enExample) |
| EP (1) | EP1196616B1 (enExample) |
| JP (1) | JP4361708B2 (enExample) |
| AT (1) | ATE286139T1 (enExample) |
| AU (1) | AU780613B2 (enExample) |
| CA (1) | CA2378586C (enExample) |
| DE (1) | DE60017141T2 (enExample) |
| ES (1) | ES2231281T3 (enExample) |
| WO (1) | WO2001004282A2 (enExample) |
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| US7589069B1 (en) * | 1999-07-12 | 2009-09-15 | Saint Louis University | Replication-competent anti-cancer vectors |
| IL152423A0 (en) | 2001-02-23 | 2003-05-29 | Novartis Ag | Novel vector constructs |
| US8163892B2 (en) * | 2002-07-08 | 2012-04-24 | Oncolys Biopharma, Inc. | Oncolytic virus replicating selectively in tumor cells |
| US20040213764A1 (en) * | 2003-03-28 | 2004-10-28 | William Wold | Adenovirus replication-competent vectors expressing trail |
| CN1871034B (zh) * | 2003-07-09 | 2011-07-06 | 亨利福特保健系统公司 | 用新型腺病毒治疗癌症的方法和组合物 |
| US7815902B2 (en) | 2003-07-09 | 2010-10-19 | Henry Ford Health System | Methods and compositions for cancer therapy using a novel adenovirus |
| WO2005049094A1 (en) * | 2003-11-13 | 2005-06-02 | Advantagene, Inc. | A mixed complementary viral vector for gene therapy |
| JP5580043B2 (ja) * | 2007-04-27 | 2014-08-27 | オンコリスバイオファーマ株式会社 | 放射線増感増強剤 |
| US8696544B2 (en) | 2009-02-05 | 2014-04-15 | Coloplast A/S | Minimally invasive adjustable support |
| WO2011146885A2 (en) * | 2010-05-21 | 2011-11-24 | Virxsys Corporation | Compositions and methods for lentiviral expression of apoa-1 or variants thereof using spliceosome mediated rna trans-splicing |
| CA2903582C (en) | 2013-03-14 | 2021-06-08 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| JP7015551B2 (ja) | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| KR20190112263A (ko) | 2016-12-12 | 2019-10-04 | 멀티비르 인코포레이티드 | 암 및 감염성 질환의 치료 및 예방을 위한 바이러스 유전자 치료요법 및 면역 체크포인트 억제제를 포함하는 방법 및 조성물 |
| CA3045892A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| US12454561B2 (en) | 2018-03-19 | 2025-10-28 | Multivir Inc. | Methods and compositions comprising tumor suppressor gene therapy and CD122/CD132 agonists for the treatment of cancer |
| AU2019251356B2 (en) * | 2018-04-09 | 2025-06-12 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions with enhanced replication properties |
| WO2021113644A1 (en) | 2019-12-05 | 2021-06-10 | Multivir Inc. | Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer |
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| US5846945A (en) | 1993-02-16 | 1998-12-08 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
| US5631236A (en) * | 1993-08-26 | 1997-05-20 | Baylor College Of Medicine | Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk |
| US6254862B1 (en) * | 1997-03-03 | 2001-07-03 | Calydon, Inc. | Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof |
| US6197293B1 (en) * | 1997-03-03 | 2001-03-06 | Calydon, Inc. | Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof |
| US7589069B1 (en) * | 1999-07-12 | 2009-09-15 | Saint Louis University | Replication-competent anti-cancer vectors |
| US6627190B2 (en) * | 1999-07-12 | 2003-09-30 | Saint Louis University | Recombinant adenovirus vectors that are replication-competent in tert-expressing cells |
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1999
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2000
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Also Published As
| Publication number | Publication date |
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| WO2001004282A3 (en) | 2001-09-13 |
| ATE286139T1 (de) | 2005-01-15 |
| US20100034776A1 (en) | 2010-02-11 |
| WO2001004282A2 (en) | 2001-01-18 |
| US7589069B1 (en) | 2009-09-15 |
| DE60017141T2 (de) | 2005-12-29 |
| EP1196616A2 (en) | 2002-04-17 |
| US8658610B2 (en) | 2014-02-25 |
| EP1196616B1 (en) | 2004-12-29 |
| US7608255B2 (en) | 2009-10-27 |
| CA2378586C (en) | 2011-05-03 |
| JP2003504052A (ja) | 2003-02-04 |
| CA2378586A1 (en) | 2001-01-18 |
| AU1324401A (en) | 2001-01-30 |
| AU780613B2 (en) | 2005-04-07 |
| US20060029596A1 (en) | 2006-02-09 |
| DE60017141D1 (de) | 2005-02-03 |
| JP4361708B2 (ja) | 2009-11-11 |
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