ES2211647T3 - Linea celular permanente de amniocitos, su preparacion y su uso para la preparacion de vectores de transferencia de genes. - Google Patents
Linea celular permanente de amniocitos, su preparacion y su uso para la preparacion de vectores de transferencia de genes.Info
- Publication number
- ES2211647T3 ES2211647T3 ES00979539T ES00979539T ES2211647T3 ES 2211647 T3 ES2211647 T3 ES 2211647T3 ES 00979539 T ES00979539 T ES 00979539T ES 00979539 T ES00979539 T ES 00979539T ES 2211647 T3 ES2211647 T3 ES 2211647T3
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- adenovirus
- cells
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2810/00—Vectors comprising a targeting moiety
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
- C12N2810/405—Vectors comprising RGD peptide
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
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- C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
- C12N2810/6018—Adenoviridae
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
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- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Manufacturing Of Steel Electrode Plates (AREA)
Applications Claiming Priority (2)
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| DE19955558 | 1999-11-18 | ||
| DE19955558A DE19955558C2 (de) | 1999-11-18 | 1999-11-18 | Permanente Amniozyten-Zelllinie, ihre Herstellung und Verwendung zur Herstellung von Gentransfervektoren |
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| EP1528101A1 (en) * | 2003-11-03 | 2005-05-04 | ProBioGen AG | Immortalized avian cell lines for virus production |
| ES2329607T3 (es) | 2004-02-23 | 2009-11-27 | Crucell Holland B.V. | Metodos de purificacion de virus. |
| DK1869171T4 (en) | 2005-04-11 | 2016-01-18 | Crucell Holland Bv | Virus cleaning using ultrafiltration |
| DE102005054628A1 (de) | 2005-11-16 | 2007-05-24 | Cevec Pharmaceuticals Gmbh | Verfahren zur Herstellung von permanenten humanen Zelllinien |
| ES2755386T5 (es) | 2006-08-28 | 2023-04-05 | Ares Trading Sa | Proceso para la purificación de proteínas que contienen fragmentos Fc |
| CA2742474C (en) | 2008-11-03 | 2016-05-31 | Crucell Holland B.V. | Method for the production of adenoviral vectors |
| DE102009003439A1 (de) | 2009-02-05 | 2010-08-26 | Cevec Pharmaceuticals Gmbh | Neue permanente humane Zelllinie |
| KR101805938B1 (ko) | 2009-10-15 | 2018-01-10 | 얀센 백신스 앤드 프리벤션 비.브이. | 고밀도 세포 배양액에서 아데노바이러스의 정제 방법 |
| AU2010305765B2 (en) | 2009-10-15 | 2015-07-02 | Crucell Holland B.V. | Method for the purification of adenovirus particles |
| JP5250155B2 (ja) | 2010-02-15 | 2013-07-31 | クルセル ホランド ベー ヴェー | Ａｄ２６アデノウイルスベクターの製造方法 |
| MX337687B (es) | 2010-08-16 | 2016-03-15 | Cevec Pharmaceuticals Gmbh | Linea celular de amniocitos humanos permanente para la produccion de virus de influenza. |
| KR101427200B1 (ko) * | 2011-11-24 | 2014-08-07 | 주식회사 바이로메드 | 아데노바이러스 생산 신규 세포주 및 그의 용도 |
| CA2864956C (en) | 2012-03-12 | 2021-11-09 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| AP2014007993A0 (en) | 2012-03-22 | 2014-10-31 | Crucell Holland Bv | Vaccine against RSV |
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| EP1445322B2 (en) * | 1995-06-15 | 2012-06-06 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
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2000
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| CZ300124B6 (cs) | 2009-02-18 |
| JP4456790B2 (ja) | 2010-04-28 |
| JP2003514526A (ja) | 2003-04-22 |
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| DE19955558C2 (de) | 2003-03-20 |
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| HU227440B1 (en) | 2011-06-28 |
| CA2391591C (en) | 2008-12-30 |
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| AU1699001A (en) | 2001-05-30 |
| DK1230354T3 (da) | 2004-03-22 |
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| HUP0203387A2 (hu) | 2002-12-28 |
| PL205966B1 (pl) | 2010-06-30 |
| AU784003B2 (en) | 2006-01-12 |
| IL149291A (en) | 2008-11-26 |
| ATE257512T1 (de) | 2004-01-15 |
| WO2001036615A2 (de) | 2001-05-25 |
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