ES2209121T3 - Sintesis de intermedios utiles en la preparacion de compuestos triciclicos. - Google Patents

Sintesis de intermedios utiles en la preparacion de compuestos triciclicos.

Info

Publication number
ES2209121T3
ES2209121T3 ES98910084T ES98910084T ES2209121T3 ES 2209121 T3 ES2209121 T3 ES 2209121T3 ES 98910084 T ES98910084 T ES 98910084T ES 98910084 T ES98910084 T ES 98910084T ES 2209121 T3 ES2209121 T3 ES 2209121T3
Authority
ES
Spain
Prior art keywords
formula
compound
alkyl
aryl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98910084T
Other languages
English (en)
Spanish (es)
Inventor
Xing Chen
Marc Poirier
Yee-Shing Wong
Guang-Zhong Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ES2209121T3 publication Critical patent/ES2209121T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/02—Monocyclic aromatic halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
ES98910084T 1997-03-25 1998-03-23 Sintesis de intermedios utiles en la preparacion de compuestos triciclicos. Expired - Lifetime ES2209121T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82392897A 1997-03-25 1997-03-25
US823928 1997-03-25

Publications (1)

Publication Number Publication Date
ES2209121T3 true ES2209121T3 (es) 2004-06-16

Family

ID=25240156

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98910084T Expired - Lifetime ES2209121T3 (es) 1997-03-25 1998-03-23 Sintesis de intermedios utiles en la preparacion de compuestos triciclicos.

Country Status (13)

Country Link
EP (1) EP0977739B1 (Direct)
JP (1) JP3476838B2 (Direct)
CN (1) CN1178919C (Direct)
AR (1) AR012147A1 (Direct)
AT (1) ATE253052T1 (Direct)
AU (1) AU6441498A (Direct)
CA (1) CA2284646C (Direct)
DE (1) DE69819316T2 (Direct)
ES (1) ES2209121T3 (Direct)
IN (1) IN186464B (Direct)
TW (1) TW513410B (Direct)
WO (1) WO1998042676A1 (Direct)
ZA (1) ZA982453B (Direct)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372909B1 (en) 1998-11-20 2002-04-16 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
HK1038698A1 (zh) * 1998-11-20 2002-03-28 Merck Sharp & Dohme Corp. 合成有效制备三环化合物的中间体
AU2001253602A1 (en) * 2000-04-18 2001-10-30 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
WO2024011415A1 (zh) * 2022-07-12 2024-01-18 苏州大学 一种邻碘苯基化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011858B1 (en) * 1978-11-29 1983-05-18 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Radioiodine containing amines, their preparation and their use as brain imaging agents
GB2094790B (en) * 1981-03-13 1985-10-09 Spofa Vereinigte Pharma Werke Tricycle compounds
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
IL117798A (en) * 1995-04-07 2001-11-25 Schering Plough Corp Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
IN186464B (Direct) 2001-09-08
JP3476838B2 (ja) 2003-12-10
JP2001507715A (ja) 2001-06-12
HK1023773A1 (en) 2000-09-22
ZA982453B (en) 1998-09-23
AR012147A1 (es) 2000-09-27
CN1178919C (zh) 2004-12-08
CA2284646A1 (en) 1998-10-01
EP0977739B1 (en) 2003-10-29
EP0977739A1 (en) 2000-02-09
ATE253052T1 (de) 2003-11-15
TW513410B (en) 2002-12-11
AU6441498A (en) 1998-10-20
DE69819316D1 (de) 2003-12-04
CN1257484A (zh) 2000-06-21
WO1998042676A1 (en) 1998-10-01
CA2284646C (en) 2004-04-06
DE69819316T2 (de) 2004-07-22

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