ES2207723T3 - Tratamiento de la bronquitis con tetrafosfato de diuridina. - Google Patents
Tratamiento de la bronquitis con tetrafosfato de diuridina.Info
- Publication number
- ES2207723T3 ES2207723T3 ES97912761T ES97912761T ES2207723T3 ES 2207723 T3 ES2207723 T3 ES 2207723T3 ES 97912761 T ES97912761 T ES 97912761T ES 97912761 T ES97912761 T ES 97912761T ES 2207723 T3 ES2207723 T3 ES 2207723T3
- Authority
- ES
- Spain
- Prior art keywords
- compound
- subject
- utp
- bronchi
- airways
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 210000001260 vocal cord Anatomy 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US744367 | 1996-11-07 | ||
| US08/744,367 US6159952A (en) | 1996-11-07 | 1996-11-07 | Method of treating bronchitis with uridine triphosphate and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2207723T3 true ES2207723T3 (es) | 2004-06-01 |
Family
ID=24992452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97912761T Expired - Lifetime ES2207723T3 (es) | 1996-11-07 | 1997-10-21 | Tratamiento de la bronquitis con tetrafosfato de diuridina. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6159952A (enExample) |
| EP (1) | EP0941099B1 (enExample) |
| JP (1) | JP2001505553A (enExample) |
| KR (1) | KR100518066B1 (enExample) |
| CN (1) | CN1115152C (enExample) |
| AT (1) | ATE249833T1 (enExample) |
| AU (1) | AU744981B2 (enExample) |
| BR (1) | BR9714312A (enExample) |
| CA (1) | CA2271126C (enExample) |
| DE (1) | DE69724991T2 (enExample) |
| ES (1) | ES2207723T3 (enExample) |
| NO (1) | NO992197L (enExample) |
| NZ (1) | NZ335540A (enExample) |
| WO (1) | WO1998019685A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319908B1 (en) | 1996-07-03 | 2001-11-20 | Inspire Pharmaceuticals, Inc. | Method for large-scale production of di(uridine 5′-tetraphosphate) and salts thereof |
| US5968913A (en) * | 1996-07-03 | 1999-10-19 | Inspire Pharmaceuticals, Inc. | Pharmaceutical compositions of uridine triphosphate |
| US5763447C1 (en) | 1996-07-23 | 2002-05-07 | Inspire Pharmaceuticals | Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds |
| EP1012154B1 (en) | 1997-07-25 | 2004-03-17 | Inspire Pharmaceuticals, Inc. | Salts of di(uridine 5'-tetraphosphate), method for preparation and uses thereof |
| US6872710B2 (en) * | 1997-07-25 | 2005-03-29 | Inspire Pharmaceuticals, Inc. | Di(uridine 5′)-tetraphosphate and salts thereof |
| TW593331B (en) * | 1997-07-25 | 2004-06-21 | Inspire Pharmaceuticals Inc | Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof |
| US6251693B1 (en) | 1998-07-30 | 2001-06-26 | Micron Technology, Inc. | Semiconductor processing methods and semiconductor defect detection methods |
| AR023088A1 (es) * | 1999-02-26 | 2002-09-04 | Inspire Pharmaceuticals Inc | Uso de disfosfatos de uridina, adenina y citidina y analogos de los mismos para la manufactura de un medicamento para la estimulacion de la hidratacion delas mucosas. |
| US7452870B2 (en) * | 2000-08-21 | 2008-11-18 | Inspire Pharmaceuticals, Inc. | Drug-eluting stents coated with P2Y12 receptor antagonist compound |
| US6555675B2 (en) | 2000-08-21 | 2003-04-29 | Inspire Pharmaceuticals, Inc. | Dinucleoside polyphosphate compositions and their therapuetic use as purinergic receptor agonists |
| US6867199B2 (en) | 2000-08-21 | 2005-03-15 | Inspire Pharmaceuticals, Inc. | Dinucleoside polyphosphate compositions and their therapeutic use |
| US7018985B1 (en) | 2000-08-21 | 2006-03-28 | Inspire Pharmaceuticals, Inc. | Composition and method for inhibiting platelet aggregation |
| GB2394419B (en) | 2001-06-25 | 2005-09-07 | Inspire Pharmaceuticals Inc | Joint lubrication with p2y purinergic receptor agonists |
| KR20050043761A (ko) * | 2001-11-06 | 2005-05-11 | 인스파이어 파마슈티컬스 인코퍼레이티드 | 염증성 질환의 치료 또는 예방 방법 |
| CN1700894A (zh) * | 2002-10-18 | 2005-11-23 | 莫利化学医药公司 | 使用羊毛硫抗生素治疗干眼病的方法 |
| EP1750740A4 (en) * | 2004-05-06 | 2009-06-10 | Molichem Medicines Inc | TREATMENT OF MEMBRANE-ASSOCIATED DISEASES AND DISORDERS USING COMPOSITIONS CONTAINING LANTIBIOTICS |
| CA2565545A1 (en) * | 2004-05-06 | 2005-12-08 | Molichem Medicines, Inc. | Treatment of ocular diseases and disorders using lantibiotic compositions |
| US7368439B2 (en) * | 2005-06-15 | 2008-05-06 | Bar - Ilan University | Dinucleoside poly(borano)phosphate derivatives and uses thereof |
| US7851456B2 (en) * | 2005-06-29 | 2010-12-14 | Inspire Pharmaceuticals, Inc. | P2Y6 receptor agonists for treating lung diseases |
| US20070249556A1 (en) * | 2006-04-21 | 2007-10-25 | Brubaker Kurt E | Method of treating inflammation |
| JP2011026204A (ja) * | 2007-11-26 | 2011-02-10 | Rei Furukawa | タバコの煙を吸入することにより引き起こされる疾患の予防及び／又は治療用組成物 |
| WO2019112383A1 (ko) * | 2017-12-08 | 2019-06-13 | 윤주석 | 금속 미네랄 디아미네이트 및 이의 제조방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2122529A1 (de) * | 1971-05-06 | 1972-12-14 | Max Planck Gesellschaft zur Förde rung der Wissenschaften e V , 3400 Gottin gen | Thiophosphatanaloge der Nucleosid di und tnphosphate sowie Verfahren zu ihrer Herstellung |
| US3960840A (en) * | 1972-12-29 | 1976-06-01 | University Of Illinois Foundaton | Fluorescent derivatives of adenine-containing compounds |
| US4501729A (en) * | 1982-12-13 | 1985-02-26 | Research Corporation | Aerosolized amiloride treatment of retained pulmonary secretions |
| GB9027968D0 (en) * | 1990-12-22 | 1991-02-13 | Fisons Plc | Method of treatment |
| DK0508687T3 (da) * | 1991-04-06 | 1996-02-05 | Astra Pharma Prod | ATP-analoger |
| FR2684299B1 (fr) * | 1991-12-02 | 1995-03-24 | Synthelabo | Compositions pharmaceutiques contenant de l'adenosine-5-triphosphate disodique et de l'amiloride. |
| FR2677250B1 (fr) * | 1991-06-05 | 1995-01-20 | Synthelabo | Compositions pharmaceutiques contenant de l'adenosine-5-triphosphate disodique. |
| EP0517573A1 (fr) * | 1991-06-05 | 1992-12-09 | Synthelabo | Compositions pharmaceutiques pour le traitement des affections des voies respiratoires |
| US5292498A (en) * | 1991-06-19 | 1994-03-08 | The University Of North Carolina At Chapel Hill | Method of treating lung disease with uridine triphosphates |
| US5635160A (en) * | 1995-06-07 | 1997-06-03 | The University Of North Carolina At Chapel Hill | Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions |
| US5628984A (en) * | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
-
1996
- 1996-11-07 US US08/744,367 patent/US6159952A/en not_active Expired - Lifetime
-
1997
- 1997-10-21 DE DE69724991T patent/DE69724991T2/de not_active Expired - Lifetime
- 1997-10-21 WO PCT/US1997/018766 patent/WO1998019685A1/en not_active Ceased
- 1997-10-21 AU AU49866/97A patent/AU744981B2/en not_active Expired
- 1997-10-21 NZ NZ335540A patent/NZ335540A/en unknown
- 1997-10-21 AT AT97912761T patent/ATE249833T1/de not_active IP Right Cessation
- 1997-10-21 JP JP52141998A patent/JP2001505553A/ja active Pending
- 1997-10-21 EP EP97912761A patent/EP0941099B1/en not_active Expired - Lifetime
- 1997-10-21 CN CN97199444A patent/CN1115152C/zh not_active Expired - Lifetime
- 1997-10-21 BR BR9714312-0A patent/BR9714312A/pt not_active Application Discontinuation
- 1997-10-21 KR KR10-1999-7004018A patent/KR100518066B1/ko not_active Expired - Fee Related
- 1997-10-21 ES ES97912761T patent/ES2207723T3/es not_active Expired - Lifetime
- 1997-10-21 CA CA002271126A patent/CA2271126C/en not_active Expired - Lifetime
-
1999
- 1999-05-05 NO NO992197A patent/NO992197L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69724991D1 (de) | 2003-10-23 |
| ATE249833T1 (de) | 2003-10-15 |
| CA2271126A1 (en) | 1998-05-14 |
| BR9714312A (pt) | 2000-05-02 |
| AU744981B2 (en) | 2002-03-07 |
| JP2001505553A (ja) | 2001-04-24 |
| CA2271126C (en) | 2008-04-08 |
| KR100518066B1 (ko) | 2005-09-28 |
| CN1115152C (zh) | 2003-07-23 |
| DE69724991T2 (de) | 2004-11-11 |
| CN1236318A (zh) | 1999-11-24 |
| US6159952A (en) | 2000-12-12 |
| EP0941099A1 (en) | 1999-09-15 |
| NZ335540A (en) | 2001-05-25 |
| AU4986697A (en) | 1998-05-29 |
| WO1998019685A1 (en) | 1998-05-14 |
| KR20000053094A (ko) | 2000-08-25 |
| EP0941099B1 (en) | 2003-09-17 |
| NO992197L (no) | 1999-07-05 |
| NO992197D0 (no) | 1999-05-05 |
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