ES2196501T3 - Utilizacion de aminoacidos marcados con c13 como agente de diagnostico en la diabetes. - Google Patents
Utilizacion de aminoacidos marcados con c13 como agente de diagnostico en la diabetes.Info
- Publication number
- ES2196501T3 ES2196501T3 ES98308523T ES98308523T ES2196501T3 ES 2196501 T3 ES2196501 T3 ES 2196501T3 ES 98308523 T ES98308523 T ES 98308523T ES 98308523 T ES98308523 T ES 98308523T ES 2196501 T3 ES2196501 T3 ES 2196501T3
- Authority
- ES
- Spain
- Prior art keywords
- labeled
- specific position
- group
- diabetes
- diagnostic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1206—Administration of radioactive gases, aerosols or breath tests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
- A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Atmospheric Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
ESTA INVENCION SE RELACIONA CON UN AGENTE DIAGNOSTICO PARA LA DIABETES QUE CONSTA DE UNA COMPOSICION ETIQUETADA CON SUP,13 C EN AL MENOS UNA POSICION ESPECIFICA SELECCIONADA A PARTIR DE UN GRUPO CONSISTENTE EN: (A) GALACTOSA, FRUCTOSA O XILOSA ETIQUETADA CON 13 C EN AL MENOS UNA POSICION ESPECIFICA, O UN ALMIDON COMPUESTO POR UNIDADES DE GLUCOSA ETIQUETADAS CON 13 C EN AL MENOS UNA POSICION ESPECIFICA; (B) UN AMINOACIDO ETIQUETADO CON 13 C EN AL MENOS UNA POSICION ESPECIFIC A; (C) ACIDO LACTICO O CITRICO ETIQUETADO CON 13 C EN AL MENOS UNA POSICION ESPECIFICA; (D) UN ACIDO GRASO ETIQUETADO CON 13 C EN AL MENOS UNA POSICION ESPECIFICA; (E) UN GLICE RIDO ETIQUETADO CON 13 C EN AL MENOS UNA POSICION ESPECIFICA; (F) GLICEROL ETIQUETADO CON 13 C EN AL MENOS UNA POS ICION ESPECIFICA; (G) AMINOPIRINA CUYO GRUPO DE DIMETILAMINO EN LA POSICION 4 ESTA ETIQUETADO CON 13 C, FENACETINA CUYO GRUPO DE ETOXI ESTA ETIQUETADO CON 13 C EN LA POSICION 1 O METACETINA CUYO GRUPO DE METOXI ESTA ETIQUETADO CON 13C.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP28862997A JP4007654B2 (ja) | 1997-10-21 | 1997-10-21 | 糖尿病診断剤 |
JP28852697A JP4007653B2 (ja) | 1997-10-21 | 1997-10-21 | 糖尿病診断剤 |
JP31376397 | 1997-11-14 | ||
JP9313077A JPH11147842A (ja) | 1997-11-14 | 1997-11-14 | 糖尿病診断剤 |
JP32080597 | 1997-11-21 | ||
JP34115497A JP4007659B2 (ja) | 1997-12-11 | 1997-12-11 | 糖尿病診断剤 |
JP00641098A JP4007663B2 (ja) | 1998-01-16 | 1998-01-16 | 糖尿病診断剤 |
JP02461498A JP4007668B2 (ja) | 1997-11-14 | 1998-02-05 | 糖尿病診断剤 |
JP02461398A JP4007667B2 (ja) | 1997-11-21 | 1998-02-05 | 糖尿病診断剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2196501T3 true ES2196501T3 (es) | 2003-12-16 |
Family
ID=27576523
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98308523T Expired - Lifetime ES2196501T3 (es) | 1997-10-21 | 1998-10-19 | Utilizacion de aminoacidos marcados con c13 como agente de diagnostico en la diabetes. |
ES03000243T Expired - Lifetime ES2304472T3 (es) | 1997-10-21 | 1998-10-19 | Agente de diagnostico para la diabetes que comprende un compuesto marcado con 13c. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES03000243T Expired - Lifetime ES2304472T3 (es) | 1997-10-21 | 1998-10-19 | Agente de diagnostico para la diabetes que comprende un compuesto marcado con 13c. |
Country Status (5)
Country | Link |
---|---|
US (1) | US6509002B1 (es) |
EP (2) | EP0913161B1 (es) |
CA (1) | CA2250485C (es) |
DE (2) | DE69839314T2 (es) |
ES (2) | ES2196501T3 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6461870B2 (en) | 1998-05-06 | 2002-10-08 | Isotechnika Inc. | 13C glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control |
US6468802B1 (en) | 1998-05-06 | 2002-10-22 | Isotechnika, Inc. | 13C glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control |
MXPA02010852A (es) * | 2000-05-02 | 2003-07-14 | Otsuka Pharma Co Ltd | Preparacion para medir la habilidad de vaciado gastrico. |
ITMI20010885A1 (it) * | 2001-04-27 | 2002-10-27 | Eurospital S P A | Metodo per la determinazione di neoplasie gastriche ed esofagee |
EP2821788A1 (de) * | 2005-06-25 | 2015-01-07 | Freie Universität Berlin | Analyseverfahren zur Bestimmung eines Organfunktionsparameters |
CA2616788C (en) * | 2005-07-25 | 2014-01-07 | Otsuka Pharmaceutical Co., Ltd. | Oral preparation useful in measuring capacity to metabolize pyridine |
US8512258B2 (en) | 2005-11-11 | 2013-08-20 | Exalenz Bioscience Ltd. | Breath test device and method |
EP1960004A4 (en) * | 2005-11-11 | 2011-04-20 | Breathid 2006 | BREATHING TEST AND METHOD |
KR101440980B1 (ko) * | 2006-04-13 | 2014-09-17 | 오츠카 세이야쿠 가부시키가이샤 | 디스펩시아 진단 검사약 |
CA2882528A1 (en) | 2012-08-20 | 2014-02-27 | Otsuka Pharmaceutical Co., Ltd. | Method for measuring carbohydrate metabolism ability, and composition for use in said method |
US10000787B2 (en) * | 2012-10-10 | 2018-06-19 | Stc.Unm | Methods for diagnosing bacterial infections |
EP2975400B1 (en) * | 2013-03-15 | 2019-09-04 | Otsuka Pharmaceutical Co., Ltd. | Composition for use in a method for measuring sugar/fatty acid combustion ratio |
JPWO2018097222A1 (ja) * | 2016-11-25 | 2019-10-17 | 大塚製薬株式会社 | 栄養状態の評価方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4298347A (en) * | 1980-02-25 | 1981-11-03 | Kor Incorporated | 13 CO2 Breath test |
US5164308A (en) * | 1990-05-21 | 1992-11-17 | Martek Corporation | Preparation of labelled triglyceride oils by cultivation of microorganisms |
US5413917A (en) * | 1990-07-18 | 1995-05-09 | Board Of Regents, The University Of Texas System | Method of determining sources of acetyl-CoA under nonsteady-state conditions |
US5227296A (en) * | 1990-09-25 | 1993-07-13 | Board Of Regents, The University Of Texas System | Enzymatic synthesis of isotopically labeled carbohydrates, nucleotides and citric acid intermediates |
IL101120A (en) * | 1991-03-08 | 1996-10-31 | Tokyo Gas Co Ltd | Preparation of compounds marked C31 |
US5834466A (en) * | 1994-12-22 | 1998-11-10 | The Regents Of The University Of California | Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia |
EP0826377B1 (en) * | 1996-08-27 | 2002-11-06 | Tokyo Gas Co., Ltd. | Diagnostic agent for diabetes |
JP3340391B2 (ja) * | 1997-09-11 | 2002-11-05 | 東京瓦斯株式会社 | 肝手術評価用試薬 |
CA2249173C (en) * | 1997-10-06 | 2008-12-16 | Tokyo Gas Co., Ltd. | Diagnostic agent for liver function |
US6468802B1 (en) * | 1998-05-06 | 2002-10-22 | Isotechnika, Inc. | 13C glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control |
-
1998
- 1998-10-14 CA CA002250485A patent/CA2250485C/en not_active Expired - Fee Related
- 1998-10-19 ES ES98308523T patent/ES2196501T3/es not_active Expired - Lifetime
- 1998-10-19 EP EP98308523A patent/EP0913161B1/en not_active Expired - Lifetime
- 1998-10-19 ES ES03000243T patent/ES2304472T3/es not_active Expired - Lifetime
- 1998-10-19 EP EP03000243A patent/EP1304124B1/en not_active Expired - Lifetime
- 1998-10-19 DE DE69839314T patent/DE69839314T2/de not_active Expired - Lifetime
- 1998-10-19 DE DE69812532T patent/DE69812532T2/de not_active Expired - Lifetime
- 1998-10-21 US US09/176,246 patent/US6509002B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69839314T2 (de) | 2009-04-09 |
CA2250485C (en) | 2008-04-29 |
EP1304124B1 (en) | 2008-03-26 |
US6509002B1 (en) | 2003-01-21 |
EP0913161A2 (en) | 1999-05-06 |
CA2250485A1 (en) | 1999-04-21 |
DE69812532T2 (de) | 2003-12-18 |
DE69812532D1 (de) | 2003-04-30 |
ES2304472T3 (es) | 2008-10-16 |
EP0913161A3 (en) | 2000-08-30 |
EP1304124A1 (en) | 2003-04-23 |
EP0913161B1 (en) | 2003-03-26 |
DE69839314D1 (de) | 2008-05-08 |
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