ES2196032T3 - Mutantes y vacunas del virus de la anemia infecciosa de los pollos y utilizaciones basadas sobre las proteinas virales vp1, vp2 y vp3 o secuencias de dicho virus que las codifican. - Google Patents
Mutantes y vacunas del virus de la anemia infecciosa de los pollos y utilizaciones basadas sobre las proteinas virales vp1, vp2 y vp3 o secuencias de dicho virus que las codifican.Info
- Publication number
- ES2196032T3 ES2196032T3 ES94925638T ES94925638T ES2196032T3 ES 2196032 T3 ES2196032 T3 ES 2196032T3 ES 94925638 T ES94925638 T ES 94925638T ES 94925638 T ES94925638 T ES 94925638T ES 2196032 T3 ES2196032 T3 ES 2196032T3
- Authority
- ES
- Spain
- Prior art keywords
- cav
- vaccines
- virus
- addition
- viruses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000700605 Viruses Species 0.000 title abstract 6
- 208000015181 infectious disease Diseases 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 208000007502 anemia Diseases 0.000 title abstract 2
- 230000002458 infectious effect Effects 0.000 title abstract 2
- 241000287828 Gallus gallus Species 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000006882 induction of apoptosis Effects 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
SE DESCRIBEN NUEVAS PROTEINAS DEL VIRUS DE ANEMIA DE POLLO Y COMPOSICIONES PARA PREVENIR O TRATAR INFECCIONES CON ESE VIRUS (CAV), EN PARTICULAR VACUNAS MENOS PATOGENICAS QUE EL PROPIO CAV, AUNQUE TODAVIA CONDUCEN A NEUTRALIZAR ANTICUERPOS EN EL ANIMAL INMUNIZADO. ADEMAS, SE DESCRIBEN COMPOSICIONES QUE CONTIENEN ANTICUERPOS CONTRA PARTES DEL CAV PARA EL CONTROL DE INFECCIONES CON CAV Y ANTICUERPOS ANTI-IDIOTIPO. LA INVENCION TAMBIEN PROPORCIONA ANTICUERPOS Y KITS DE PRUEBA PARA LA DETECCION DE CAV. MEDIANTE ESTA INVENCION, SE HACEN POSIBLES MOLECULAS DE ADN RECOMBINANTE DERIVADAS DE CAV Y CELULAS HUESPED TRASFERIDAS CON LAS MISMAS Y VACUNAS BASADAS EN ESTAS CELULAS HUESPED. LA INVENCION TAMBIEN COMPRENDE VACUNAS DE VIRUS VIVO EN LAS QUE UNA PIEZA DE ADN SE LLEVA A UN VIRUS INFECCIOSO PARA LA CELULA. ADEMAS, LA INVENCION PROPORCIONA USOS DE PROTEINAS DE CAV EN LA INDUCCION DE APOPTOSIS, EN PARTICULAR EN CELULAS TUMORALES. ADEMAS PROPORCIONA LA INDUCCION DE MUERTE CELULAR POR MEDIO DE TERAPIAGENICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9301272A NL9301272A (nl) | 1993-07-20 | 1993-07-20 | Chicken Anemia Virus mutanten en vaccins en toepassingen gebaseerd op de virale eiwitten VP1, VP2 en VP3 of daarvoor coderende sequenties van dat virus. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2196032T3 true ES2196032T3 (es) | 2003-12-16 |
Family
ID=19862681
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94925638T Expired - Lifetime ES2196032T3 (es) | 1993-07-20 | 1994-07-19 | Mutantes y vacunas del virus de la anemia infecciosa de los pollos y utilizaciones basadas sobre las proteinas virales vp1, vp2 y vp3 o secuencias de dicho virus que las codifican. |
ES01205103T Expired - Lifetime ES2311005T3 (es) | 1993-07-20 | 1994-07-19 | Mutantes y vacunas del virus de la anemia infecciosa de los pollos basadas sobre la proteina viral vp3 o secuencias de dicho virus que las codifica. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES01205103T Expired - Lifetime ES2311005T3 (es) | 1993-07-20 | 1994-07-19 | Mutantes y vacunas del virus de la anemia infecciosa de los pollos basadas sobre la proteina viral vp3 o secuencias de dicho virus que las codifica. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5952002A (es) |
EP (2) | EP1253201B1 (es) |
JP (1) | JP3829290B2 (es) |
AT (2) | ATE236980T1 (es) |
AU (1) | AU703187B2 (es) |
CA (1) | CA2167578C (es) |
DE (2) | DE69435117D1 (es) |
DK (2) | DK0784685T3 (es) |
ES (2) | ES2196032T3 (es) |
NL (1) | NL9301272A (es) |
PT (2) | PT1253201E (es) |
WO (1) | WO1995003414A2 (es) |
ZA (1) | ZA945275B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080234466A1 (en) * | 1990-09-12 | 2008-09-25 | Noteborn Mathieu H M | Delivery method for the tumor-specific apoptosis-inducing activity of apoptin |
US6162461A (en) * | 1990-09-12 | 2000-12-19 | Leadd B.V. | Chicken anemia virus mutants and vaccines and uses based on the viral proteins VP1, VP2 and VP3 or sequences of that virus coding therefor |
EP0872552A1 (en) * | 1997-04-15 | 1998-10-21 | Leadd B.V. | A gene delivery vehicle expressing the apoptosis-inducing proteins VP2 and/or Apoptin |
EP0878546A1 (en) * | 1997-04-15 | 1998-11-18 | Leadd B.V. | A gene delivery vehicle expressing the apoptosis-inducing proteins VP2 and/or apoptin |
US5789567A (en) * | 1994-07-06 | 1998-08-04 | Cornell Research Foundation, Inc. | Chicken infectious anemia virus vaccine |
GB9414888D0 (en) * | 1994-07-23 | 1994-09-14 | Univ Belfast | Method and composition |
ES2200065T3 (es) * | 1995-06-07 | 2004-03-01 | Leadd B.V. | Utilizacion de apoptina. |
JPH11510367A (ja) * | 1995-06-07 | 1999-09-14 | アエスキュラープ ビー.ヴィ. | ニワトリ貧血ウイルスの中和性立体配座エピトープ |
EP0927757A1 (en) * | 1997-12-03 | 1999-07-07 | Leadd B.V. | Methods and means for inducing apoptosis by interfering with Bip-like proteins |
US7361730B1 (en) * | 1999-03-15 | 2008-04-22 | University Of Maryland | Surface localized colligin/Hsp47 in carcinoma cells |
EP1199363A1 (en) * | 2000-10-20 | 2002-04-24 | Leadd B.V. | Phosphorylation modifications of apoptin |
AUPR567401A0 (en) * | 2001-06-14 | 2001-07-12 | University Of Melbourne, The | Circovirus vaccines |
EP2275132B1 (en) | 2005-12-29 | 2021-03-03 | Boehringer Ingelheim Animal Health USA Inc. | Multivalent PCV2 immunogenic compositions and methods of producing them |
EP2371382B1 (en) | 2005-12-29 | 2016-03-02 | Boehringer Ingelheim Vetmedica, Inc. | Use of a PCV2 immunogenic composition for lessening clinical symptoms in pigs |
CN102311928B (zh) * | 2011-08-25 | 2013-04-24 | 中国农业科学院哈尔滨兽医研究所 | 鸡贫血病毒vp1、vp2蛋白共表达的重组酵母工程菌、其构建方法及应用 |
JP7088835B2 (ja) | 2015-10-16 | 2022-06-21 | カンザス ステイト ユニバーシティ リサーチ ファウンデーション | ブタサーコウイルス3型免疫原性組成物、その製造方法、およびその使用方法 |
WO2017187131A1 (en) * | 2016-04-26 | 2017-11-02 | London School Of Hygiene & Tropical Medicine | Reoviridae vaccine |
CN113980146B (zh) * | 2021-11-11 | 2022-09-27 | 扬州优邦生物药品有限公司 | 三聚体化鸭黄病毒E蛋白domainIII、其制备方法和运用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL9002008A (nl) * | 1990-09-12 | 1992-04-01 | Stichting Centr Diergeneeskund | Recombinant dna en rna en daarvan afgeleide produkten. |
ZA918426B (en) * | 1990-10-31 | 1992-12-30 | Akzo Nv | Chicken anemia virus vaccine and diagnostic |
ZA927014B (en) * | 1991-09-20 | 1993-03-19 | Akzo Nv | Chicken anaemia agent vaccine. |
-
1993
- 1993-07-20 NL NL9301272A patent/NL9301272A/nl not_active Application Discontinuation
-
1994
- 1994-07-19 ZA ZA945275A patent/ZA945275B/xx unknown
- 1994-07-19 AU AU75473/94A patent/AU703187B2/en not_active Ceased
- 1994-07-19 EP EP01205103A patent/EP1253201B1/en not_active Expired - Lifetime
- 1994-07-19 JP JP50507295A patent/JP3829290B2/ja not_active Expired - Lifetime
- 1994-07-19 AT AT94925638T patent/ATE236980T1/de not_active IP Right Cessation
- 1994-07-19 DE DE69435117T patent/DE69435117D1/de not_active Expired - Fee Related
- 1994-07-19 CA CA002167578A patent/CA2167578C/en not_active Expired - Fee Related
- 1994-07-19 DK DK94925638T patent/DK0784685T3/da active
- 1994-07-19 DE DE69432486T patent/DE69432486T2/de not_active Expired - Fee Related
- 1994-07-19 AT AT01205103T patent/ATE401406T1/de not_active IP Right Cessation
- 1994-07-19 ES ES94925638T patent/ES2196032T3/es not_active Expired - Lifetime
- 1994-07-19 WO PCT/NL1994/000168 patent/WO1995003414A2/en active IP Right Grant
- 1994-07-19 ES ES01205103T patent/ES2311005T3/es not_active Expired - Lifetime
- 1994-07-19 PT PT01205103T patent/PT1253201E/pt unknown
- 1994-07-19 DK DK01205103T patent/DK1253201T3/da active
- 1994-07-19 PT PT94925638T patent/PT784685E/pt unknown
- 1994-07-19 EP EP94925638A patent/EP0784685B1/en not_active Expired - Lifetime
-
1997
- 1997-08-14 US US08/911,092 patent/US5952002A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1995003414A3 (en) | 1995-03-02 |
AU7547394A (en) | 1995-02-20 |
ATE401406T1 (de) | 2008-08-15 |
EP0784685B1 (en) | 2003-04-09 |
JPH09504941A (ja) | 1997-05-20 |
NL9301272A (nl) | 1995-02-16 |
DK0784685T3 (da) | 2003-08-04 |
ATE236980T1 (de) | 2003-04-15 |
DE69432486T2 (de) | 2004-03-04 |
DK1253201T3 (da) | 2008-11-17 |
PT1253201E (pt) | 2008-10-27 |
EP1253201A2 (en) | 2002-10-30 |
EP1253201A3 (en) | 2003-01-08 |
WO1995003414A2 (en) | 1995-02-02 |
EP0784685A2 (en) | 1997-07-23 |
ES2311005T3 (es) | 2009-02-01 |
CA2167578C (en) | 2007-03-13 |
DE69435117D1 (de) | 2008-08-28 |
ZA945275B (en) | 1995-02-24 |
JP3829290B2 (ja) | 2006-10-04 |
EP1253201B1 (en) | 2008-07-16 |
US5952002A (en) | 1999-09-14 |
CA2167578A1 (en) | 1995-02-02 |
AU703187B2 (en) | 1999-03-18 |
PT784685E (pt) | 2003-08-29 |
DE69432486D1 (de) | 2003-05-15 |
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