ES2189537T3 - Derivados aromaticos y complejos de hierro de los mismos para su uso como agentes normalizantes del nivel de hierro. - Google Patents

Derivados aromaticos y complejos de hierro de los mismos para su uso como agentes normalizantes del nivel de hierro.

Info

Publication number
ES2189537T3
ES2189537T3 ES99971418T ES99971418T ES2189537T3 ES 2189537 T3 ES2189537 T3 ES 2189537T3 ES 99971418 T ES99971418 T ES 99971418T ES 99971418 T ES99971418 T ES 99971418T ES 2189537 T3 ES2189537 T3 ES 2189537T3
Authority
ES
Spain
Prior art keywords
iron
same
aromatic derivatives
complexes
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99971418T
Other languages
English (en)
Inventor
Napoli Guido Di
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Medidom SA
Original Assignee
Laboratoire Medidom SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Medidom SA filed Critical Laboratoire Medidom SA
Application granted granted Critical
Publication of ES2189537T3 publication Critical patent/ES2189537T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Composiciones farmacéuticas que comprenden como ingrediente activo al menos un compuesto de fórmula (I) **(Fórmula)** en la que R1 es **(Fórmula)** en la que R3 y R4 se escogen entre H y OH, siempre que R3 y R4 no sean H simultáneamente, y R2 es H; o R1 y R2, conjuntamente, son**(Fórmula)** en el que R5 es (CH2)5OH, o un complejo de hierro del mismo.
ES99971418T 1998-11-02 1999-10-29 Derivados aromaticos y complejos de hierro de los mismos para su uso como agentes normalizantes del nivel de hierro. Expired - Lifetime ES2189537T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002350A IT1303688B1 (it) 1998-11-02 1998-11-02 Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo.

Publications (1)

Publication Number Publication Date
ES2189537T3 true ES2189537T3 (es) 2003-07-01

Family

ID=11380986

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99971418T Expired - Lifetime ES2189537T3 (es) 1998-11-02 1999-10-29 Derivados aromaticos y complejos de hierro de los mismos para su uso como agentes normalizantes del nivel de hierro.

Country Status (17)

Country Link
US (1) US6455578B1 (es)
EP (1) EP1124814B1 (es)
JP (1) JP2002528539A (es)
AR (1) AR021037A1 (es)
AT (1) ATE229947T1 (es)
AU (1) AU756726B2 (es)
BR (1) BR9914863A (es)
CA (1) CA2348380C (es)
CZ (1) CZ299542B6 (es)
DE (1) DE69904635T2 (es)
DK (1) DK1124814T3 (es)
ES (1) ES2189537T3 (es)
IL (2) IL142813A0 (es)
IT (1) IT1303688B1 (es)
PL (1) PL198826B1 (es)
SK (1) SK286308B6 (es)
WO (1) WO2000026205A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100234366A1 (en) * 2006-03-29 2010-09-16 Bsf Se Use of Strobilurins for the Treatment of Disorders of Iron Metabolism

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4122200A (en) * 1974-11-20 1978-10-24 Lipha, Lyonnaise Industrielle Pharmaceutique 6',2-(2'Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof
ATE14579T1 (de) * 1979-03-20 1985-08-15 Fisons Plc Pharmazeutische heterocyclische verbindungen, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen.
EP0346279A1 (de) * 1988-06-06 1989-12-13 Ciba-Geigy Ag Propan-1,3-dionderivate und deren Verwendung als Stabilisatoren für chlorhaltige Polymerisate

Also Published As

Publication number Publication date
US6455578B1 (en) 2002-09-24
IT1303688B1 (it) 2001-02-23
ATE229947T1 (de) 2003-01-15
DE69904635D1 (de) 2003-01-30
CA2348380A1 (en) 2000-05-11
DE69904635T2 (de) 2003-10-02
CZ299542B6 (cs) 2008-08-27
ITMI982350A1 (it) 2000-05-02
IL142813A (en) 2006-12-10
AU756726B2 (en) 2003-01-23
PL198826B1 (pl) 2008-07-31
CZ20011461A3 (cs) 2001-08-15
EP1124814B1 (en) 2002-12-18
AR021037A1 (es) 2002-06-12
WO2000026205A1 (en) 2000-05-11
PL347940A1 (en) 2002-04-22
SK5562001A3 (en) 2001-09-11
IL142813A0 (en) 2002-03-10
BR9914863A (pt) 2001-07-03
AU1157300A (en) 2000-05-22
EP1124814A1 (en) 2001-08-22
CA2348380C (en) 2009-02-17
SK286308B6 (en) 2008-07-07
JP2002528539A (ja) 2002-09-03
DK1124814T3 (da) 2003-04-14

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