BR9914863A - Derivados aromáticos e complexos de ferro dos mesmos para uso como agentes de normalização do nìvel de ferro - Google Patents

Derivados aromáticos e complexos de ferro dos mesmos para uso como agentes de normalização do nìvel de ferro

Info

Publication number
BR9914863A
BR9914863A BR9914863-3A BR9914863A BR9914863A BR 9914863 A BR9914863 A BR 9914863A BR 9914863 A BR9914863 A BR 9914863A BR 9914863 A BR9914863 A BR 9914863A
Authority
BR
Brazil
Prior art keywords
iron
aromatic derivatives
complexes
normalizing agents
level normalizing
Prior art date
Application number
BR9914863-3A
Other languages
English (en)
Inventor
Di Guido Napoli
Original Assignee
Medidom Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medidom Lab filed Critical Medidom Lab
Publication of BR9914863A publication Critical patent/BR9914863A/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

<B>"DERIVADOS AROMáTICOS E COMPLEXOS DE FERRO DOS MESMOS PARA USO COMO AGENTES DE NORMALIZAçãO DO NìVEL DE FERRO"<D>. A presente invenção se refere à derivados aromáticos de fórmula (I), em que R~ 1~ é (a), R~ 3~ e R~ 4~ são selecionados entre H e OH, desde que R~ 3~ e R~ 4~ não sejam simultaneamente H, e R~ 2~ é H; ou R~ 1~ e R~ 2~ tomados juntos, representam (b), onde R~ 5~ é selecionado dentre CH~ 3~ e (CH~ 2~) ~ 5~OH, para os complexos de ferro do mesmo e ao seu uso para preparação de composições farmacêuticas para a normalização do nível de ferro.
BR9914863-3A 1998-11-02 1999-10-29 Derivados aromáticos e complexos de ferro dos mesmos para uso como agentes de normalização do nìvel de ferro BR9914863A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002350A IT1303688B1 (it) 1998-11-02 1998-11-02 Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo.
PCT/EP1999/008222 WO2000026205A1 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for the use as normalising agents of the iron level

Publications (1)

Publication Number Publication Date
BR9914863A true BR9914863A (pt) 2001-07-03

Family

ID=11380986

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914863-3A BR9914863A (pt) 1998-11-02 1999-10-29 Derivados aromáticos e complexos de ferro dos mesmos para uso como agentes de normalização do nìvel de ferro

Country Status (17)

Country Link
US (1) US6455578B1 (pt)
EP (1) EP1124814B1 (pt)
JP (1) JP2002528539A (pt)
AR (1) AR021037A1 (pt)
AT (1) ATE229947T1 (pt)
AU (1) AU756726B2 (pt)
BR (1) BR9914863A (pt)
CA (1) CA2348380C (pt)
CZ (1) CZ299542B6 (pt)
DE (1) DE69904635T2 (pt)
DK (1) DK1124814T3 (pt)
ES (1) ES2189537T3 (pt)
IL (2) IL142813A0 (pt)
IT (1) IT1303688B1 (pt)
PL (1) PL198826B1 (pt)
SK (1) SK286308B6 (pt)
WO (1) WO2000026205A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009531379A (ja) * 2006-03-29 2009-09-03 ビーエーエスエフ ソシエタス・ヨーロピア 鉄代謝機能障害を治療するためのストロビルリンの使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4122200A (en) * 1974-11-20 1978-10-24 Lipha, Lyonnaise Industrielle Pharmaceutique 6',2-(2'Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof
ATE14579T1 (de) * 1979-03-20 1985-08-15 Fisons Plc Pharmazeutische heterocyclische verbindungen, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen.
EP0346279A1 (de) * 1988-06-06 1989-12-13 Ciba-Geigy Ag Propan-1,3-dionderivate und deren Verwendung als Stabilisatoren für chlorhaltige Polymerisate

Also Published As

Publication number Publication date
AU756726B2 (en) 2003-01-23
US6455578B1 (en) 2002-09-24
DE69904635T2 (de) 2003-10-02
IL142813A0 (en) 2002-03-10
ITMI982350A1 (it) 2000-05-02
JP2002528539A (ja) 2002-09-03
AR021037A1 (es) 2002-06-12
CZ20011461A3 (cs) 2001-08-15
ATE229947T1 (de) 2003-01-15
DK1124814T3 (da) 2003-04-14
DE69904635D1 (de) 2003-01-30
SK286308B6 (en) 2008-07-07
CA2348380C (en) 2009-02-17
IT1303688B1 (it) 2001-02-23
PL347940A1 (en) 2002-04-22
IL142813A (en) 2006-12-10
PL198826B1 (pl) 2008-07-31
ES2189537T3 (es) 2003-07-01
WO2000026205A1 (en) 2000-05-11
SK5562001A3 (en) 2001-09-11
EP1124814B1 (en) 2002-12-18
AU1157300A (en) 2000-05-22
EP1124814A1 (en) 2001-08-22
CA2348380A1 (en) 2000-05-11
CZ299542B6 (cs) 2008-08-27

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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B09B Patent application refused [chapter 9.2 patent gazette]

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