ES2187047T3 - Composicion y metodo para la regulacion de la proliferacion celular y la muerte celular. - Google Patents

Composicion y metodo para la regulacion de la proliferacion celular y la muerte celular.

Info

Publication number
ES2187047T3
ES2187047T3 ES98938555T ES98938555T ES2187047T3 ES 2187047 T3 ES2187047 T3 ES 2187047T3 ES 98938555 T ES98938555 T ES 98938555T ES 98938555 T ES98938555 T ES 98938555T ES 2187047 T3 ES2187047 T3 ES 2187047T3
Authority
ES
Spain
Prior art keywords
dna
composition
animal
regulation
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98938555T
Other languages
English (en)
Spanish (es)
Inventor
Nigel C Phillips
Mario C Filion
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Telesta Therapeutics Inc
Original Assignee
Bioniche Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioniche Life Sciences Inc filed Critical Bioniche Life Sciences Inc
Application granted granted Critical
Publication of ES2187047T3 publication Critical patent/ES2187047T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES98938555T 1997-08-05 1998-08-05 Composicion y metodo para la regulacion de la proliferacion celular y la muerte celular. Expired - Lifetime ES2187047T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5477797P 1997-08-05 1997-08-05
US7506798P 1998-02-18 1998-02-18
US7511198P 1998-02-18 1998-02-18
US8631798P 1998-05-21 1998-05-21

Publications (1)

Publication Number Publication Date
ES2187047T3 true ES2187047T3 (es) 2003-05-16

Family

ID=27489673

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98938555T Expired - Lifetime ES2187047T3 (es) 1997-08-05 1998-08-05 Composicion y metodo para la regulacion de la proliferacion celular y la muerte celular.

Country Status (17)

Country Link
US (2) US6326357B1 (https=)
EP (1) EP1003525B1 (https=)
JP (2) JP4335435B2 (https=)
KR (1) KR100533576B1 (https=)
AT (1) ATE227996T1 (https=)
AU (1) AU736450B2 (https=)
BR (1) BR9815602A (https=)
CA (1) CA2299548C (https=)
DE (1) DE69809561T2 (https=)
DK (1) DK1003525T3 (https=)
ES (1) ES2187047T3 (https=)
HU (1) HU227921B1 (https=)
IL (3) IL134371A0 (https=)
NO (1) NO322450B1 (https=)
NZ (1) NZ502674A (https=)
PT (1) PT1003525E (https=)
WO (1) WO1999007383A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100533576B1 (ko) 1997-08-05 2005-12-05 바이오니취 라이프 사이언시즈 인코포레이티드 세포증식 및 세포사멸 조절용 조성물 및 방법
CN1153576C (zh) * 1998-02-18 2004-06-16 比奥尼斯生命科学公司 用于治疗膀胱癌的组合物和方法
WO2000033879A1 (en) * 1998-12-04 2000-06-15 Bioniche Life Sciences Inc. Method for the treatment of inflammation
CA2353905C (en) * 1998-12-04 2010-06-22 Nigel C. Phillips Chemotherapeutic composition and method
US6809081B1 (en) 1998-12-04 2004-10-26 Bioniche Life Sciences, Inc. Chemotherapeutic composition and method
WO2000059518A2 (en) * 1999-04-01 2000-10-12 Bioniche Life Sciences Inc. Composition and method for inducing apoptosis in prostate cancer cells
US6794368B1 (en) 1999-04-01 2004-09-21 Bioniche Life Sciences Inc. Composition and method for inducing apoptosis in prostate cancer cells
JP2002541264A (ja) 1999-04-08 2002-12-03 ユーエイビー・リサーチ・ファウンデーション 冨ｇオリゴヌクレオチドの抗増殖活性およびヌクレオリンに結合するためのその使用方法
AU7501700A (en) * 1999-09-29 2001-04-30 Bioniche Life Sciences Inc. Method to disrupt mitochondrial function
EP1867718B1 (en) * 1999-12-13 2010-01-20 Bioniche Life Sciences Inc. Therapeutically useful synthetic oligonucleotides
CA2395493C (en) * 1999-12-28 2010-06-22 Bioniche Life Sciences Inc. Hyaluronic acid in the treatment of cancer
US20030044352A1 (en) * 2001-04-24 2003-03-06 Phillips Nigel C. Method for evaluating the efficacy of treatment with bacterial DNA and bacterial cell walls
US6673566B1 (en) 2002-01-10 2004-01-06 The United States Of America As Represented By The Secretary Of Agriculture Diagnosis of pathogen infections through analysis of nitrite production by antigen stimulated leukocytes
US8299015B2 (en) * 2006-07-25 2012-10-30 Lipoxen Technologies Limited Derivatisation of granulocyte colony-stimulating factor
CN105943559A (zh) 2010-10-13 2016-09-21 特莱斯塔治疗知识产权公司 细菌核糖核酸细胞壁组合物及其制备和使用方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3172815A (en) 1962-04-24 1965-03-09 Warner Lambert Pharmaceutical Method for preparing reticulo-endo-thelial system stimulant and stimulant thereof
FR2160326B1 (https=) 1971-11-19 1975-02-07 Anvar
US4152423A (en) 1971-11-19 1979-05-01 Agence Nationale De Valorisation De La Recherche (Anvar) Immunological agents
CA1020460A (en) 1973-02-23 1977-11-08 Wellcome Foundation Limited (The) Isolation of immunostimulating glycopeptide from bacteria
US3976544A (en) 1973-06-19 1976-08-24 The Agence Nationale De Valorisation De Le Recherche Water-soluble immunological adjuvants, in particular for vaccines, obtained from mycobacteria and related microorganisms and process for their extraction
FR2374042A1 (fr) 1976-06-04 1978-07-13 Merieux Inst Nouveau medicament immunostimulant et son procede de preparation
JPS54140710A (en) 1978-03-10 1979-11-01 Mitsui Toatsu Chem Inc Anti-tumor substance and its preparation
DE3011461C2 (de) 1980-03-25 1986-10-30 Dr. Madaus & Co, 5000 Köln Verwendung von Propionibakterien
US4520019A (en) 1982-04-29 1985-05-28 Ribi Immunochem Research, Inc. Stable composition and preparation thereof
US4579941A (en) 1982-08-13 1986-04-01 Mitsuitoatsu Chemicals, Inc. Thermally-denatured deoxyribonucleic acid MD-011 and antitumor agent
US4663306A (en) 1983-09-23 1987-05-05 Ribi Immunochem Research, Inc. Pyridine-soluble extract-refined detoxified endotoxin composition and use
GB8404280D0 (en) 1984-02-17 1984-03-21 Stanford J L Biological preparations
US4744984A (en) 1985-10-08 1988-05-17 Vetrepharm Research, Inc. Antiviral immunotherapeutic agent and preparation thereof
US4877611A (en) 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
BR9406496A (pt) 1993-01-29 1996-01-02 Vetrepharm Inc Processo e composição para estimulação do sistema imunológico em um ser humano ou animal
KR100533576B1 (ko) 1997-08-05 2005-12-05 바이오니취 라이프 사이언시즈 인코포레이티드 세포증식 및 세포사멸 조절용 조성물 및 방법

Also Published As

Publication number Publication date
US6329347B1 (en) 2001-12-11
NO20000576D0 (no) 2000-02-04
HUP0003012A2 (hu) 2000-12-28
HUP0003012A3 (en) 2004-03-29
NO20000576L (no) 2000-04-04
US6326357B1 (en) 2001-12-04
JP2008208140A (ja) 2008-09-11
IL180924A0 (en) 2007-07-04
AU8723698A (en) 1999-03-01
NO322450B1 (no) 2006-10-09
WO1999007383B1 (en) 1999-03-25
HU227921B1 (hu) 2012-06-28
DK1003525T3 (da) 2003-03-24
PT1003525E (pt) 2003-03-31
IL134371A0 (en) 2001-04-30
JP2001513504A (ja) 2001-09-04
AU736450B2 (en) 2001-07-26
ATE227996T1 (de) 2002-12-15
IL134371A (en) 2007-07-24
BR9815602A (pt) 2001-12-11
EP1003525A1 (en) 2000-05-31
EP1003525B1 (en) 2002-11-20
KR20010022643A (ko) 2001-03-26
DE69809561D1 (de) 2003-01-02
CA2299548A1 (en) 1999-02-18
IL180924A (en) 2010-11-30
JP4335435B2 (ja) 2009-09-30
NZ502674A (en) 2002-06-28
KR100533576B1 (ko) 2005-12-05
CA2299548C (en) 2009-12-29
WO1999007383A1 (en) 1999-02-18
DE69809561T2 (de) 2003-09-25

Similar Documents

Publication Publication Date Title
ES2187047T3 (es) Composicion y metodo para la regulacion de la proliferacion celular y la muerte celular.
CY1119742T1 (el) Βιολογικα συστηματα μεταφορας πολλαπλου-συστατικου
ES2173314T3 (es) Metodos y composiciones para la modificacion selectiva de acidos nucleicos.
TR200002355T2 (tr) 2-(Pürin-9-il)tetrahidrofüran-3,4-diol türevleri
ES2191192T3 (es) Tienopirimidinas.
BR9808068A (pt) Processo in vitro para eliminar células tumorosas de uma população de células que inclui células não-tumorosas, para enriquecerr o número de células germinativas numa população de células hematopoéticas, para preparar células hematopoéticas isoladas para reintrodução num paciente, para a eliminação de uma primeira população de células de uma segunda população de células, e, processo de eliminação de células tumorosas de uma população de células que inclui células não-tumorosas
ES2162284T3 (es) Proceso para la fabricacion de tensioactivos que contienen grupos alquilo de cadena ramificada.
MX9705954A (es) Formulaciones y metodos para reducir irritacion de la piel.
ES2196181T3 (es) Derivados de purina y proceso para su preparacion.
EP1411118A4 (en) Cell proliferation inhibitors with anti-glycanic-3 antibody
ES2193145T3 (es) Proteinas procoagulants quimericas.
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
ES2060947T3 (es) Un nuevo sistema de suministro de anticuerpos para modificadores de la respuesta biologica.
NO331101B1 (no) In vitro-fremgangsmate for a uttrykke et antigenmolekyl og antigenmolekyl og et fotosensibiliserende middel for anvendelse ved uttrykking av antigenmolekylet.
PE20010694A1 (es) Plasmido autonomamente reproducible en bacterias corineformes
CO5011082A1 (es) Formulacion medicamentosa con liberacion controlada de sus- tancia activa
ES2144507T3 (es) Potencializador de la actividad pesticida de bacillus.
DK1900811T3 (da) Berigede cellepopulationer i centralnervesystemet
BRPI0518579A2 (pt) mÉtodo para aumentar a atividade de cÉlula exterminadora natural em um animal, kit adequado para alimentar Ácido lipàico a um animal, meio para comunicar informaÇço, composiÇço, uso da composiÇço que compreende Ácido lipàico, e, mÉtodo para aumentar a resposta imune em um animal
CY1105439T1 (el) Κυτταρα, μεθοδοι καλλιεργειας και η χρηση τους στη θepαπεια με αυτολογη μεταμοσχευση
Kashket et al. Accumulation of methylglyoxal in the gingival crevicular fluid of chronic periodontitis patients
ATE291621T1 (de) Nukleinsaeuren und proteine der katze fc-epsilon rezeptor alpha-kette und deren verwendungen
AR017190A1 (es) Metodo para mejorar la resistencia o tolerancia a patogenos en una planta que comprende integrar en el genoma de dicha planta un gen que codificauna proteina de fusion que comprende una primer y segunda proteina o dominio de proteina con actividad antipatogenica, molecula de adn, su uso, proteinade
ES2052482T1 (es) Inhibidora de la proliferacion de celulas endoteliales.
BR0208879A (pt) Artigo