NO331101B1 - In vitro-fremgangsmate for a uttrykke et antigenmolekyl og antigenmolekyl og et fotosensibiliserende middel for anvendelse ved uttrykking av antigenmolekylet. - Google Patents

In vitro-fremgangsmate for a uttrykke et antigenmolekyl og antigenmolekyl og et fotosensibiliserende middel for anvendelse ved uttrykking av antigenmolekylet.

Info

Publication number
NO331101B1
NO331101B1 NO20014491A NO20014491A NO331101B1 NO 331101 B1 NO331101 B1 NO 331101B1 NO 20014491 A NO20014491 A NO 20014491A NO 20014491 A NO20014491 A NO 20014491A NO 331101 B1 NO331101 B1 NO 331101B1
Authority
NO
Norway
Prior art keywords
antigen molecule
expressing
photosensitizing agent
vitro method
molecule
Prior art date
Application number
NO20014491A
Other languages
English (en)
Other versions
NO20014491L (no
NO20014491D0 (no
Inventor
Kristian Berg
Anders Hogset
Torunn E Tjelle
Lina Prasmickaite
Original Assignee
Photocure Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Photocure Asa filed Critical Photocure Asa
Publication of NO20014491D0 publication Critical patent/NO20014491D0/no
Publication of NO20014491L publication Critical patent/NO20014491L/no
Publication of NO331101B1 publication Critical patent/NO331101B1/no

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20014491A 1999-03-15 2001-09-14 In vitro-fremgangsmate for a uttrykke et antigenmolekyl og antigenmolekyl og et fotosensibiliserende middel for anvendelse ved uttrykking av antigenmolekylet. NO331101B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9905911.5A GB9905911D0 (en) 1999-03-15 1999-03-15 Method
PCT/GB2000/000903 WO2000054802A2 (en) 1999-03-15 2000-03-10 Method of expressing antigens on the surface of antigen presenting cells by photochemical internalization

Publications (3)

Publication Number Publication Date
NO20014491D0 NO20014491D0 (no) 2001-09-14
NO20014491L NO20014491L (no) 2001-11-14
NO331101B1 true NO331101B1 (no) 2011-10-03

Family

ID=10849643

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014491A NO331101B1 (no) 1999-03-15 2001-09-14 In vitro-fremgangsmate for a uttrykke et antigenmolekyl og antigenmolekyl og et fotosensibiliserende middel for anvendelse ved uttrykking av antigenmolekylet.

Country Status (19)

Country Link
US (2) US8216587B1 (no)
EP (1) EP1223973B1 (no)
JP (1) JP4922490B2 (no)
KR (1) KR100769113B1 (no)
CN (1) CN100379450C (no)
AT (1) ATE419866T1 (no)
AU (1) AU771990B2 (no)
CA (1) CA2367357C (no)
CZ (1) CZ299370B6 (no)
DE (1) DE60041347D1 (no)
DK (1) DK1223973T3 (no)
ES (1) ES2319255T3 (no)
GB (1) GB9905911D0 (no)
HU (1) HU227604B1 (no)
MX (1) MXPA01009316A (no)
NO (1) NO331101B1 (no)
NZ (1) NZ514228A (no)
PL (1) PL208221B1 (no)
WO (1) WO2000054802A2 (no)

Families Citing this family (29)

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Publication number Priority date Publication date Assignee Title
CN100490902C (zh) * 2000-11-29 2009-05-27 Pci生物技术联合股份有限公司 病毒介导的分子传递进入胞质溶胶的光化学内在化
AU2002220853B2 (en) 2000-11-29 2007-06-28 Pci Biotech As Photochemical internalization for delivery of molecules into the cytosol
US20030031655A1 (en) * 2001-02-08 2003-02-13 Sequitur, Inc. Methods of light activated release of ligands from endosomes
GB0121023D0 (en) 2001-08-30 2001-10-24 Norwegian Radium Hospital Res Compound
EP2213292B2 (en) 2002-02-01 2016-06-22 Life Technologies Corporation Double-stranded oligonucleotides
US20060009409A1 (en) 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
GB0613753D0 (en) 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
ES2603418T3 (es) 2006-10-04 2017-02-27 Janssen Pharmaceutica Nv Preparación de células presentadoras de antígeno artificial inactivado y su uso en terapias celulares
GB0811955D0 (en) * 2008-06-30 2008-07-30 Pci Biotech As Method
GB0914286D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Method
GB0914287D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Compositions
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
US20160040128A1 (en) * 2013-03-15 2016-02-11 Pci Biotech As Method
KR102374556B1 (ko) * 2013-08-28 2022-03-14 피씨아이 바이오테크 에이에스 백신접종 및 면역화를 위한 화합물 및 방법
GB2517707B (en) * 2013-08-28 2020-09-02 Pci Biotech As A device for light-induced rupture of endocytic vesicles to effect the delivery of an antigen
WO2015028575A1 (en) * 2013-08-28 2015-03-05 Pci Biotech As Immunisation method by photochemical internalisation
EP3129045B1 (en) 2014-04-11 2022-03-02 PCI Biotech AS Method of treating melanoma
US10537639B2 (en) 2014-08-28 2020-01-21 Pci Biotech As Compound and method
GB201415250D0 (en) * 2014-08-28 2014-10-15 Pci Biotech As Compound and method
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
CA3040344A1 (en) 2016-10-14 2018-04-19 Pci Biotech As Treatment of cholangiocarcinoma with tpcs-2a induced photochemical internalisation of gemcitabine
CN107029236B (zh) * 2017-04-18 2020-04-10 中国医学科学院生物医学工程研究所 一种吲哚菁绿自组装纳米疫苗及制备方法
CN107217041B (zh) * 2017-07-11 2020-05-15 深圳华云生物技术有限公司 具有高抗原呈递的dc细胞和抗原特异性t细胞及其制备方法和应用
GB201718631D0 (en) 2017-11-10 2017-12-27 Pci Biotech As Method
WO2020017962A1 (en) 2018-07-16 2020-01-23 Dcprime B.V. A combination product for use in tumor vaccination.
CA3133410A1 (en) 2019-04-25 2020-10-29 Dcprime B.V. Methods of tumor vaccination
WO2021191871A1 (en) 2020-03-27 2021-09-30 Dcprime B.V. In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
GB202101726D0 (en) 2021-02-08 2021-03-24 Pci Biotech As Method
GB202115451D0 (en) 2021-10-27 2021-12-08 Pci Biotech As Method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258453A (en) 1992-01-21 1993-11-02 University Of Utah Drug delivery system for the simultaneous delivery of drugs activatable by enzymes and light
US20020168374A1 (en) 1992-08-07 2002-11-14 Ralph T. Kubo Hla binding peptides and their uses
US5820872A (en) 1992-11-18 1998-10-13 Yale University Methods and compositions for improving the effectiveness of X-irradiation therapy for the treatment of an internal solid tumor
US5651993A (en) * 1992-11-18 1997-07-29 Yale University Specific immune system modulation
NO180167C (no) * 1994-09-08 1997-02-26 Photocure As Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
US6008211A (en) * 1995-07-27 1999-12-28 Pdt Pharmaceuticals, Inc. Photoactivatable compounds comprising benzochlorin and furocoumarin
WO1998050387A1 (en) * 1997-05-07 1998-11-12 Qlt Phototherapeutics, Inc. Ethylene glycol esters of monohydrobenzoporphyrin derivatives as photoactive agents
AU2002220853B2 (en) 2000-11-29 2007-06-28 Pci Biotech As Photochemical internalization for delivery of molecules into the cytosol
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
KR102374556B1 (ko) 2013-08-28 2022-03-14 피씨아이 바이오테크 에이에스 백신접종 및 면역화를 위한 화합물 및 방법

Also Published As

Publication number Publication date
HU227604B1 (en) 2011-09-28
KR100769113B1 (ko) 2007-10-22
GB9905911D0 (en) 1999-05-05
PL208221B1 (pl) 2011-03-31
US9737594B2 (en) 2017-08-22
WO2000054802A2 (en) 2000-09-21
NO20014491L (no) 2001-11-14
WO2000054802A3 (en) 2002-05-10
AU771990B2 (en) 2004-04-08
EP1223973A2 (en) 2002-07-24
JP2002541072A (ja) 2002-12-03
EP1223973B1 (en) 2009-01-07
CN1376073A (zh) 2002-10-23
CZ299370B6 (cs) 2008-07-09
KR20010110664A (ko) 2001-12-13
HUP0202441A2 (en) 2002-10-28
DE60041347D1 (de) 2009-02-26
US8216587B1 (en) 2012-07-10
NO20014491D0 (no) 2001-09-14
ES2319255T3 (es) 2009-05-06
HUP0202441A3 (en) 2004-07-28
MXPA01009316A (es) 2003-07-14
NZ514228A (en) 2004-01-30
CA2367357A1 (en) 2000-09-21
US20130330363A1 (en) 2013-12-12
CZ20013328A3 (cs) 2002-03-13
JP4922490B2 (ja) 2012-04-25
AU3177100A (en) 2000-10-04
DK1223973T3 (da) 2009-05-04
ATE419866T1 (de) 2009-01-15
CN100379450C (zh) 2008-04-09
PL355015A1 (en) 2004-03-22
CA2367357C (en) 2015-01-06

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