ES2185683T3 - Venlafaxina y sus analogos para inducir una mejora de las funciones cognitivas. - Google Patents

Venlafaxina y sus analogos para inducir una mejora de las funciones cognitivas.

Info

Publication number
ES2185683T3
ES2185683T3 ES95300612T ES95300612T ES2185683T3 ES 2185683 T3 ES2185683 T3 ES 2185683T3 ES 95300612 T ES95300612 T ES 95300612T ES 95300612 T ES95300612 T ES 95300612T ES 2185683 T3 ES2185683 T3 ES 2185683T3
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
venlafaxina
analogs
induce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95300612T
Other languages
English (en)
Inventor
George Edward Morris Husbands
Magid Abdel-Megid Abou-Gharbia
John Allen Moyer
Eric Anthony Muth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Application granted granted Critical
Publication of ES2185683T3 publication Critical patent/ES2185683T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Traffic Control Systems (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

LA INVENCION SUMINISTRA UN COMPUESTO PARA MANUFACTURAR UN MEDICAMENTO PARA INDUCIR LA MEJORA DEL CONOCIMIENTO. EL COMPUESTO ES UN DERIVADO DEL 2-(1-HIDROXICICLOALQUIL O 1-HIDROXICICLOALQUENIL)-2FENILALQUILAMINO QUE TIENE LA FORMULA (I) EN LA QUE A ES UNA MOLECULA DE LA FORMULA (II) EN LA QUE LA LINEA PUNTEADA REPRESENTA UNA INSATURACION OPCIONAL; R1 ES HIDROGENO O ALQUILO; R2 ES ALQUILO; R4 ES HIDROGENO, ALQUILO, FORMILO O ALCANOILO; R5 Y R6 SON, INDEPENDIENTEMENTE, HIDROGENO, HIDROXILO, ALQUILO, ALCOXI, ALCANOILOXI, CIANO, NITRO, ALQUILMERCAPTO, AMINO, ALQUILAMINO, DIALQUILAMINO, ALCANAMIDO, HALO, TRIFLUOROMETILO, O TOMADAS JUNTAS, DIOXIDO DE METILENO; R7 ES HIDROGENO O ALQUILO; Y N ES 0, 1, 2, 3 O 4, TAMBIEN SE PRESENTAN LAS SALES FARMACOLOGICAMENTE ACEPTABLES DEL COMPUESTO.
ES95300612T 1994-02-14 1995-01-31 Venlafaxina y sus analogos para inducir una mejora de las funciones cognitivas. Expired - Lifetime ES2185683T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19541794A 1994-02-14 1994-02-14

Publications (1)

Publication Number Publication Date
ES2185683T3 true ES2185683T3 (es) 2003-05-01

Family

ID=22721346

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95300612T Expired - Lifetime ES2185683T3 (es) 1994-02-14 1995-01-31 Venlafaxina y sus analogos para inducir una mejora de las funciones cognitivas.

Country Status (11)

Country Link
EP (2) EP1245228A3 (es)
JP (1) JPH07252143A (es)
AT (1) ATE229328T1 (es)
CA (1) CA2141774A1 (es)
CY (1) CY2321B1 (es)
DE (1) DE69529109T2 (es)
DK (1) DK0667150T3 (es)
ES (1) ES2185683T3 (es)
LV (1) LV13000B (es)
PT (1) PT667150E (es)
SG (1) SG49680A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274171B1 (en) 1996-03-25 2001-08-14 American Home Products Corporation Extended release formulation of venlafaxine hydrochloride
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
PL350924A1 (en) * 1999-04-06 2003-02-10 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
HUP0303128A3 (en) † 2001-02-12 2008-03-28 Wyeth Corp Novel succinate salt of o-desmethyl-venlafaxine, process for preparation thereof, its use and pharmaceutical composition containing it

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
EP1153603B1 (en) * 1993-06-28 2006-10-18 Wyeth New treatments using phenethylamine derivatives

Also Published As

Publication number Publication date
CY2321B1 (en) 2003-11-14
CA2141774A1 (en) 1995-08-15
ATE229328T1 (de) 2002-12-15
LV13000B (en) 2003-07-20
DK0667150T3 (da) 2003-03-31
EP1245228A3 (en) 2002-10-09
EP0667150B1 (en) 2002-12-11
DE69529109D1 (de) 2003-01-23
DE69529109T2 (de) 2003-04-30
EP1245228A2 (en) 2002-10-02
EP0667150A1 (en) 1995-08-16
PT667150E (pt) 2003-02-28
SG49680A1 (en) 1998-06-15
JPH07252143A (ja) 1995-10-03

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