ATE71622T1 - Neue benzothiazinabkoemmlinge. - Google Patents

Neue benzothiazinabkoemmlinge.

Info

Publication number
ATE71622T1
ATE71622T1 AT86904393T AT86904393T ATE71622T1 AT E71622 T1 ATE71622 T1 AT E71622T1 AT 86904393 T AT86904393 T AT 86904393T AT 86904393 T AT86904393 T AT 86904393T AT E71622 T1 ATE71622 T1 AT E71622T1
Authority
AT
Austria
Prior art keywords
hydrogen
pct
lower alkyl
nitro
sec
Prior art date
Application number
AT86904393T
Other languages
English (en)
Inventor
Jun-Ichi Iwao
Tadashi Iso
Masayuki Oya
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1985/000426 external-priority patent/WO1987000837A1/ja
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE71622T1 publication Critical patent/ATE71622T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Sheets, Magazines, And Separation Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT86904393T 1985-07-29 1986-07-21 Neue benzothiazinabkoemmlinge. ATE71622T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/JP1985/000426 WO1987000837A1 (fr) 1985-07-29 1985-07-29 Nouveaux derives de benzothiazine
JP17353185 1985-08-06
EP86904393A EP0237573B1 (de) 1985-07-29 1986-07-21 Neue benzothiazinabkömmlinge
PCT/JP1986/000379 WO1987000838A1 (fr) 1985-07-29 1986-07-21 Nouveaux derives de benzothiazine

Publications (1)

Publication Number Publication Date
ATE71622T1 true ATE71622T1 (de) 1992-02-15

Family

ID=15962257

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86904393T ATE71622T1 (de) 1985-07-29 1986-07-21 Neue benzothiazinabkoemmlinge.

Country Status (10)

Country Link
US (1) US4786635A (de)
EP (1) EP0237573B1 (de)
KR (1) KR890004196B1 (de)
AT (1) ATE71622T1 (de)
AU (1) AU587057B2 (de)
DE (1) DE3683483D1 (de)
DK (1) DK158087D0 (de)
FI (1) FI87352C (de)
NO (1) NO170082C (de)
WO (1) WO1987000838A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3614363A1 (de) * 1986-04-28 1987-10-29 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389113B (de) * 1987-10-08 1989-10-25 Hoechst Ag Neue benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389112B (de) * 1987-10-08 1989-10-25 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
ATE142881T1 (de) * 1989-06-16 1996-10-15 Santen Pharmaceutical Co Ltd Arzneimittel für bessere gehirnwirkung
TW207952B (de) * 1990-11-29 1993-06-21 Santen Pharmaceutical Co Ltd
CA2319551A1 (en) * 1998-03-31 1999-10-07 Warner-Lambert Company Benzoxazinones/benzothiazinones as serine protease inhibitors
CN1681495B (zh) 2002-08-19 2010-05-12 辉瑞产品公司 用于治疗过度增生性疾病的组合物
CA2574958A1 (en) * 2004-07-26 2006-02-09 Cotherix, Inc. Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
JP2009513660A (ja) * 2005-10-26 2009-04-02 旭化成ファーマ株式会社 肺動脈性高血圧の治療用併用療法におけるファスジル
EP2351569B1 (de) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Kombinationstherapie mit Fasudil zur Behandlung von pulmonaler Hypertonie
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US20090069413A1 (en) * 2007-09-09 2009-03-12 Protia, Llc Deuterium-enriched olopatadine
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
BR112015026513A2 (pt) 2013-04-17 2017-07-25 Pfizer derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
RS66416B1 (sr) 2019-01-18 2025-02-28 Astrazeneca Ab 6'-[[(1s,3s)-3-[[5-(difluorometoksi)-2-pirimidinil]amino]ciklopentil]amino][1(2h),3'-bipiridin]-2-on kao inhibitor pcsk9 i metode njegove primene

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5651465A (en) * 1979-10-02 1981-05-09 Yoshitomi Pharmaceut Ind Ltd Benzothiazine derivative
JPS59144775A (ja) * 1983-02-07 1984-08-18 Santen Pharmaceut Co Ltd ヒドロキシフエニルベンゾチアジン誘導体およびその製造法
JPS59148771A (ja) * 1983-02-09 1984-08-25 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
US4584300A (en) * 1983-02-07 1986-04-22 Santen Pharmaceutical Co., Ltd. Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor
DE3347173A1 (de) * 1983-12-27 1985-07-04 Hoechst Ag, 6230 Frankfurt Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
JPS60166674A (ja) * 1984-02-09 1985-08-29 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
EP0233291B1 (de) * 1985-03-19 1991-03-13 Santen Pharmaceutical Co., Ltd. 2-(arylbenzothiazin)-derivate
AU4673285A (en) * 1985-07-29 1987-03-05 Santen Pharmaceutical Co. Ltd. Novel benzothiazine derivatives

Also Published As

Publication number Publication date
FI871322A7 (fi) 1987-03-26
FI87352C (fi) 1992-12-28
EP0237573A1 (de) 1987-09-23
KR870700613A (ko) 1987-12-30
NO871314D0 (no) 1987-03-27
AU587057B2 (en) 1989-08-03
DE3683483D1 (de) 1992-02-27
FI871322A0 (fi) 1987-03-26
EP0237573B1 (de) 1992-01-15
US4786635A (en) 1988-11-22
FI87352B (fi) 1992-09-15
DK158087A (da) 1987-03-27
WO1987000838A1 (fr) 1987-02-12
AU6137186A (en) 1987-03-05
EP0237573A4 (de) 1987-10-26
NO170082B (no) 1992-06-01
NO170082C (no) 1992-09-09
KR890004196B1 (ko) 1989-10-27
DK158087D0 (da) 1987-03-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee