ATE71622T1 - Neue benzothiazinabkoemmlinge. - Google Patents

Neue benzothiazinabkoemmlinge.

Info

Publication number
ATE71622T1
ATE71622T1 AT86904393T AT86904393T ATE71622T1 AT E71622 T1 ATE71622 T1 AT E71622T1 AT 86904393 T AT86904393 T AT 86904393T AT 86904393 T AT86904393 T AT 86904393T AT E71622 T1 ATE71622 T1 AT E71622T1
Authority
AT
Austria
Prior art keywords
hydrogen
pct
lower alkyl
nitro
sec
Prior art date
Application number
AT86904393T
Other languages
English (en)
Inventor
Jun-Ichi Iwao
Tadashi Iso
Masayuki Oya
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1985/000426 external-priority patent/WO1987000837A1/ja
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE71622T1 publication Critical patent/ATE71622T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Sheets, Magazines, And Separation Thereof (AREA)
AT86904393T 1985-07-29 1986-07-21 Neue benzothiazinabkoemmlinge. ATE71622T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/JP1985/000426 WO1987000837A1 (fr) 1985-07-29 1985-07-29 Nouveaux derives de benzothiazine
JP17353185 1985-08-06
EP86904393A EP0237573B1 (de) 1985-07-29 1986-07-21 Neue benzothiazinabkömmlinge
PCT/JP1986/000379 WO1987000838A1 (fr) 1985-07-29 1986-07-21 Nouveaux derives de benzothiazine

Publications (1)

Publication Number Publication Date
ATE71622T1 true ATE71622T1 (de) 1992-02-15

Family

ID=15962257

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86904393T ATE71622T1 (de) 1985-07-29 1986-07-21 Neue benzothiazinabkoemmlinge.

Country Status (10)

Country Link
US (1) US4786635A (de)
EP (1) EP0237573B1 (de)
KR (1) KR890004196B1 (de)
AT (1) ATE71622T1 (de)
AU (1) AU587057B2 (de)
DE (1) DE3683483D1 (de)
DK (1) DK158087D0 (de)
FI (1) FI87352C (de)
NO (1) NO170082C (de)
WO (1) WO1987000838A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3614363A1 (de) * 1986-04-28 1987-10-29 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389112B (de) * 1987-10-08 1989-10-25 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389113B (de) * 1987-10-08 1989-10-25 Hoechst Ag Neue benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DK0429676T3 (de) * 1989-06-16 1997-03-10 Santen Pharmaceutical Co Ltd
EP0492164B1 (de) * 1990-11-29 1996-02-07 Santen Pharmaceutical Co., Ltd Therapeutisches Mittel gegen Glaukom, das 2-Phenyl-3-oxo-2H-1,4-Benzothiazinderivate enthält
IL137656A0 (en) 1998-03-31 2001-10-31 Warner Lambert Co Benzoxazinones/benzothiazinones as serine protease inhibitors
EP1545519B1 (de) 2002-08-19 2011-03-23 Pfizer Inc. Kombinationstherapie gegen hyperproliferative erkrankungen
EP1796653A2 (de) * 2004-07-26 2007-06-20 Actelion Pharmaceuticals Ltd. Behandlung von pulmonaler hypertonie durch inhaliertes iloprost mit einer mikroteilchen-formulierung
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
EP2351569B1 (de) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Kombinationstherapie mit Fasudil zur Behandlung von pulmonaler Hypertonie
US7893050B2 (en) * 2005-10-26 2011-02-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
US20090069413A1 (en) * 2007-09-09 2009-03-12 Protia, Llc Deuterium-enriched olopatadine
US8883844B2 (en) 2010-09-24 2014-11-11 Nitrogenix Inc. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
US11248001B2 (en) 2019-01-18 2022-02-15 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5651465A (en) * 1979-10-02 1981-05-09 Yoshitomi Pharmaceut Ind Ltd Benzothiazine derivative
JPS59148771A (ja) * 1983-02-09 1984-08-25 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
JPS59144775A (ja) * 1983-02-07 1984-08-18 Santen Pharmaceut Co Ltd ヒドロキシフエニルベンゾチアジン誘導体およびその製造法
US4584300A (en) * 1983-02-07 1986-04-22 Santen Pharmaceutical Co., Ltd. Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor
DE3347173A1 (de) * 1983-12-27 1985-07-04 Hoechst Ag, 6230 Frankfurt Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
JPS60166674A (ja) * 1984-02-09 1985-08-29 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
AU5511986A (en) * 1985-03-19 1986-10-13 Santen Pharmaceutical Co. Ltd. 2-arylbenzothiazine derivatives
AU4673285A (en) * 1985-07-29 1987-03-05 Santen Pharmaceutical Co. Ltd. Novel benzothiazine derivatives

Also Published As

Publication number Publication date
FI87352B (fi) 1992-09-15
NO170082B (no) 1992-06-01
EP0237573A1 (de) 1987-09-23
NO170082C (no) 1992-09-09
FI871322A7 (fi) 1987-03-26
DK158087A (da) 1987-03-27
DE3683483D1 (de) 1992-02-27
KR890004196B1 (ko) 1989-10-27
AU587057B2 (en) 1989-08-03
KR870700613A (ko) 1987-12-30
FI871322A0 (fi) 1987-03-26
EP0237573A4 (de) 1987-10-26
AU6137186A (en) 1987-03-05
US4786635A (en) 1988-11-22
WO1987000838A1 (fr) 1987-02-12
EP0237573B1 (de) 1992-01-15
DK158087D0 (da) 1987-03-27
NO871314D0 (no) 1987-03-27
FI87352C (fi) 1992-12-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee