ES8705405A1 - Procedimiento de preparar nuevos derivados morfolinicos - Google Patents

Procedimiento de preparar nuevos derivados morfolinicos

Info

Publication number
ES8705405A1
ES8705405A1 ES551058A ES551058A ES8705405A1 ES 8705405 A1 ES8705405 A1 ES 8705405A1 ES 551058 A ES551058 A ES 551058A ES 551058 A ES551058 A ES 551058A ES 8705405 A1 ES8705405 A1 ES 8705405A1
Authority
ES
Spain
Prior art keywords
preparation
treatment
nervous system
central nervous
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551058A
Other languages
English (en)
Other versions
ES551058A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of ES551058A0 publication Critical patent/ES551058A0/es
Publication of ES8705405A1 publication Critical patent/ES8705405A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

METODO DE OBTENER NUEVOS DERIVADOS MORFOLINICOS. CONSISTE EN HACER REACCIONAR UN EPOXIDO DE FORMULA (II) CON HIDROGENOSULFATO DE AMINO-2-ETILO (ESTER) DE FORMULA (III), EN METANOL, Y EN PRESENCIA DE UNA BASE INORGANICA, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES DE ACIDOS MINERALES U ORGANICAS TERAPEUTICAMENTE ACEPTABLES, SIENDO AR UN GRUPO AROMATICO Y UN GRUPO DE FORMULA (IV); A, UN RADICAL ALQUILENO LINEAL O RAMIFICADO DE C 1 A 4; R, H, ALCOILO, HAL Y OTROS; Y N, 2 O 3. SON UTILES PARA TRATAR LAS MOLESTIAS DELSISTEMA CENTRAL.-
ES551058A 1984-12-20 1985-12-20 Procedimiento de preparar nuevos derivados morfolinicos Expired ES8705405A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8419553A FR2575158B1 (fr) 1984-12-20 1984-12-20 Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central

Publications (2)

Publication Number Publication Date
ES551058A0 ES551058A0 (es) 1987-05-16
ES8705405A1 true ES8705405A1 (es) 1987-05-16

Family

ID=9310832

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551058A Expired ES8705405A1 (es) 1984-12-20 1985-12-20 Procedimiento de preparar nuevos derivados morfolinicos

Country Status (6)

Country Link
US (1) US4605654A (es)
EP (1) EP0187096A1 (es)
JP (1) JPS61158971A (es)
ES (1) ES8705405A1 (es)
FR (1) FR2575158B1 (es)
ZA (1) ZA859695B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870074A (en) * 1986-04-30 1989-09-26 Dainippon Pharmaceutical Co., Ltd. Substituted benzamide derivatives, for enhancing gastrointestinal motility
US7294637B2 (en) * 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
AU9087301A (en) * 2000-09-11 2002-03-26 Sepracor Inc Ligands for monoamine receptors and transporters, and methods of use thereof
JP2005034165A (ja) * 2002-06-26 2005-02-10 Mu-Hyun Cho マット一体型のストーンベッド
KR101738868B1 (ko) 2009-07-31 2017-05-23 글로벌 알리앙스 포 티비 드럭 디벨롭먼트 니트로이미다조옥사진 및 니트로이미다조옥사졸 동족체 및 이들의 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138405A (en) * 1966-12-28 1969-01-01 Ici Ltd Morpholine derivatives
GB1260886A (en) * 1969-06-20 1972-01-19 Ici Ltd Process for aryloxymethylmorpholine derivatives
DE2728898A1 (de) * 1977-06-27 1979-01-18 Thomae Gmbh Dr K Neue morpholinderivate
FR2479814A1 (fr) * 1980-04-04 1981-10-09 Fabre Sa Pierre Phenyl alcoxy propanolamines, leur preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
FR2575158B1 (fr) 1987-10-02
ES551058A0 (es) 1987-05-16
FR2575158A1 (fr) 1986-06-27
US4605654A (en) 1986-08-12
EP0187096A1 (fr) 1986-07-09
JPS61158971A (ja) 1986-07-18
ZA859695B (en) 1986-08-27

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