ES2184475T3 - Modificaciones cristalinas de acido lipoico. - Google Patents

Modificaciones cristalinas de acido lipoico.

Info

Publication number
ES2184475T3
ES2184475T3 ES99932864T ES99932864T ES2184475T3 ES 2184475 T3 ES2184475 T3 ES 2184475T3 ES 99932864 T ES99932864 T ES 99932864T ES 99932864 T ES99932864 T ES 99932864T ES 2184475 T3 ES2184475 T3 ES 2184475T3
Authority
ES
Spain
Prior art keywords
lipoic acid
crystal modifications
crystal
modifications
intense
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99932864T
Other languages
English (en)
Inventor
Martin Jochen Klatt
Markus Niebel
Joachim Paust
Jens Rieger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2184475T3 publication Critical patent/ES2184475T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

Ácido R- o S-lipoico cristalino enantioméricamente puro, siendo las líneas de reflexión a 2 = 3º las más intensas en el intervalo entre 15º y 30 º en el diagrama de difracción 2 .
ES99932864T 1998-07-31 1999-07-12 Modificaciones cristalinas de acido lipoico. Expired - Lifetime ES2184475T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19834608A DE19834608A1 (de) 1998-07-31 1998-07-31 Kristallmodifikation der Liponsäure

Publications (1)

Publication Number Publication Date
ES2184475T3 true ES2184475T3 (es) 2003-04-01

Family

ID=7876020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99932864T Expired - Lifetime ES2184475T3 (es) 1998-07-31 1999-07-12 Modificaciones cristalinas de acido lipoico.

Country Status (19)

Country Link
US (1) US6441024B1 (es)
EP (1) EP1100793B1 (es)
JP (1) JP2002522430A (es)
KR (1) KR20010072109A (es)
CN (1) CN1198815C (es)
AT (1) ATE224385T1 (es)
AU (1) AU751485B2 (es)
BR (1) BR9912622A (es)
CA (1) CA2338991A1 (es)
DE (2) DE19834608A1 (es)
DK (1) DK1100793T3 (es)
ES (1) ES2184475T3 (es)
HU (1) HUP0103405A3 (es)
IL (1) IL140826A (es)
NO (1) NO20010516L (es)
RU (1) RU2226528C2 (es)
TW (1) TWI250158B (es)
WO (1) WO2000008012A1 (es)
ZA (1) ZA200101609B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000344739A (ja) * 1999-06-01 2000-12-12 Sumitomo Chem Co Ltd Ｎ−保護−アゼチジン−２−カルボン酸の製造方法
AU2001291677A1 (en) 2000-08-02 2002-02-13 Basf Aktiengesellschaft Method for producing lipoic acid and dihydrolipoic acid
IT1319195B1 (it) * 2000-10-10 2003-09-26 Laboratorio Chimico Int Spa Processo per la produzione dell'acido r(+)alfa-lipoico.
EP1339705B1 (de) * 2000-11-30 2006-06-07 Basf Aktiengesellschaft Verfahren zur herstellung von liponsäure und dihydroliponsaüre
DE10137381A1 (de) * 2001-07-31 2003-02-13 Viatris Gmbh Neue Modifikationen des Trometamolsalzes der R-Thioctsäure sowie Verfahren zu ihrer Herstellung
DE10201464B4 (de) * 2002-01-16 2005-06-16 Viatris Gmbh & Co. Kg Verfahren zur Herstellung reiner Thioctsäure
JP4849792B2 (ja) * 2004-09-14 2012-01-11 オリザ油化株式会社 美容用組成物
US20090176864A1 (en) * 2004-11-24 2009-07-09 Hill's Pet Nutrition, Inc. Methods For Improving Hepatic and Immune Function In An Animal
CA2588709C (en) * 2004-11-24 2015-07-14 Hill's Pet Nutrition, Inc. Use of lipoic acid to improve hepatic clearance of xenobiotic substances
US8148325B2 (en) * 2004-12-30 2012-04-03 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
US8252742B2 (en) 2004-12-30 2012-08-28 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
JP2006219467A (ja) * 2005-02-10 2006-08-24 Oriza Yuka Kk 脂肪蓄積阻害剤
JP2006321732A (ja) * 2005-05-18 2006-11-30 Fancl Corp 異常蛋白質除去及び８−ヒドロキシ２’−デオキシグアノシン増加抑制用組成物
KR20110103987A (ko) * 2008-12-01 2011-09-21 인베이스크 테라퓨틱, 인크. 레닌-안지오텐신 알도스테론계 억제제 및 리포산 화합물을 포함하는 조성물, 및 레닌-안지오텐신 알도스테론계 관련 질환의 치료를 위한 이의 용도
US7928067B2 (en) 2009-05-14 2011-04-19 Ischemix Llc Compositions and methods for treating ischemia and ischemia-reperfusion injury
ITMI20111286A1 (it) * 2011-07-11 2013-01-12 Laboratorio Chimico Int Spa Nuova forma cristallina
CN103880815A (zh) * 2014-03-06 2014-06-25 南京海融医药科技有限公司 ɑ-硫辛酸的多晶型物及其制备方法和应用
EP3615023B1 (en) 2017-04-25 2023-06-21 Ischemix LLC Lipoyl-glu-ala for the treatment of neurodegenerative damage caused by traumatic brain injury

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4037440A1 (de) 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
JP3696233B2 (ja) 1991-07-19 2005-09-14 ミシガン、ステート、ユニバーシティー ポリヒドロキシアルカノエートを生産するトランスジェニック植物
DE4137773A1 (de) 1991-11-16 1993-05-19 Degussa Herstellung und verwendung von salzen der reinen enantiomere der (alpha)-liponsaeure
DE4229914A1 (de) 1992-09-08 1994-03-10 Basf Ag Verbessertes Verfahren zur Herstellung von R/S-Ï-Liponsäure oder R/S-â-Liponsäure
DE59308496D1 (de) 1992-09-08 1998-06-10 Basf Ag Verbessertes Verfahren zur Herstellung von R/S-gamma-Liponsäure oder R/S-alpha-Liponsäure
DE4235912C2 (de) 1992-10-23 2002-12-05 Viatris Gmbh Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung
DE19810336A1 (de) * 1998-03-11 1999-09-23 Asta Medica Ag Alpha-Liponsäure mit neuartiger Modifikation

Also Published As

Publication number Publication date
ATE224385T1 (de) 2002-10-15
DK1100793T3 (da) 2002-10-14
CN1311784A (zh) 2001-09-05
AU751485B2 (en) 2002-08-15
ZA200101609B (en) 2002-06-27
RU2226528C2 (ru) 2004-04-10
HUP0103405A2 (hu) 2002-04-29
NO20010516D0 (no) 2001-01-30
AU4909499A (en) 2000-02-28
US6441024B1 (en) 2002-08-27
IL140826A (en) 2004-06-01
NO20010516L (no) 2001-01-30
TWI250158B (en) 2006-03-01
EP1100793B1 (de) 2002-09-18
EP1100793A1 (de) 2001-05-23
BR9912622A (pt) 2001-04-24
WO2000008012A1 (de) 2000-02-17
JP2002522430A (ja) 2002-07-23
HUP0103405A3 (en) 2003-01-28
DE19834608A1 (de) 2000-02-03
IL140826A0 (en) 2002-02-10
KR20010072109A (ko) 2001-07-31
CN1198815C (zh) 2005-04-27
CA2338991A1 (en) 2000-02-17
DE59902779D1 (de) 2002-10-24

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