ES2181256T3 - Particulas de tamaño nanometrico con un nucleo de oxido de hierro rodeado por al menos dos cortezas. - Google Patents

Particulas de tamaño nanometrico con un nucleo de oxido de hierro rodeado por al menos dos cortezas.

Info

Publication number
ES2181256T3
ES2181256T3 ES98939520T ES98939520T ES2181256T3 ES 2181256 T3 ES2181256 T3 ES 2181256T3 ES 98939520 T ES98939520 T ES 98939520T ES 98939520 T ES98939520 T ES 98939520T ES 2181256 T3 ES2181256 T3 ES 2181256T3
Authority
ES
Spain
Prior art keywords
core
particles
iron oxide
shell
cortezas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98939520T
Other languages
English (en)
Spanish (es)
Inventor
Christoph Lesniak
Thomas Schiestel
Helmut Schmidt
Andreas Jordan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INM Leibniz Institut fuer Neue Materialien Ggmbh
Original Assignee
INM Leibniz Institut fuer Neue Materialien Ggmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INM Leibniz Institut fuer Neue Materialien Ggmbh filed Critical INM Leibniz Institut fuer Neue Materialien Ggmbh
Application granted granted Critical
Publication of ES2181256T3 publication Critical patent/ES2181256T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Hard Magnetic Materials (AREA)
  • Compounds Of Iron (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES98939520T 1997-06-20 1998-06-19 Particulas de tamaño nanometrico con un nucleo de oxido de hierro rodeado por al menos dos cortezas. Expired - Lifetime ES2181256T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19726282A DE19726282A1 (de) 1997-06-20 1997-06-20 Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern

Publications (1)

Publication Number Publication Date
ES2181256T3 true ES2181256T3 (es) 2003-02-16

Family

ID=7833178

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98939520T Expired - Lifetime ES2181256T3 (es) 1997-06-20 1998-06-19 Particulas de tamaño nanometrico con un nucleo de oxido de hierro rodeado por al menos dos cortezas.

Country Status (10)

Country Link
US (2) US6541039B1 (https=)
EP (1) EP1001811B1 (https=)
JP (2) JP4902900B2 (https=)
CN (1) CN1211127C (https=)
AT (1) ATE223731T1 (https=)
DE (2) DE19726282A1 (https=)
DK (1) DK1001811T3 (https=)
ES (1) ES2181256T3 (https=)
PT (1) PT1001811E (https=)
WO (1) WO1998058673A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2320837A1 (es) * 2007-07-26 2009-05-28 Consejo Superior De Investigaciones Cientificas Dispositivo de hipertermia y su utilizacion con nanoparticulas.

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
DE19921088C2 (de) * 1999-04-30 2003-08-07 Magforce Applic Gmbh Stent zur Offenhaltung gangartiger Strukturen
DE19924138A1 (de) 1999-05-26 2000-11-30 Henkel Kgaa Lösbare Klebeverbindungen
DE19940220B4 (de) 1999-08-19 2007-05-03 Magforce Nanotechnologies Ag Medizinisches Präparat zur Behandlung von Arthrose, Arthritis und anderen rheumatischen Gelenkerkrankungen
EP1228158B1 (de) * 1999-08-24 2008-07-30 Henkel AG & Co. KGaA Verklebung durch Klebstoffe enthaltend nanoskalige Teilchen
DE19951599A1 (de) 1999-10-27 2001-05-23 Henkel Kgaa Verfahren zur adhesiven Trennung von Klebeverbunden
AU3679801A (en) * 2000-02-08 2001-08-20 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
DE10020376A1 (de) * 2000-04-26 2001-11-08 Inst Zelltechnologie E V Dynamische Marker
DE10037884A1 (de) 2000-08-03 2002-02-21 Henkel Kgaa Verfahren zur beschleunigten Klebstoffaushärtung
DE10037883A1 (de) 2000-08-03 2002-02-14 Henkel Kgaa Ferromagnetische Resonanzanregung und ihre Verwendung zur Erwärmung teilchengefüllter Substrate
DE10141674A1 (de) 2000-09-01 2002-03-14 Henkel Kgaa Reaktionsklebstoff mit mindestens einer mikroverkapselten Komponente
US7951061B2 (en) * 2001-07-25 2011-05-31 Allan Foreman Devices for targeted delivery of thermotherapy, and methods related thereto
US7731648B2 (en) * 2001-07-25 2010-06-08 Aduro Biotech Magnetic nanoscale particle compositions, and therapeutic methods related thereto
US7074175B2 (en) * 2001-07-25 2006-07-11 Erik Schroeder Handy Thermotherapy via targeted delivery of nanoscale magnetic particles
US6997863B2 (en) * 2001-07-25 2006-02-14 Triton Biosystems, Inc. Thermotherapy via targeted delivery of nanoscale magnetic particles
EP1438971A4 (en) * 2001-10-25 2005-01-12 Ttc Co Ltd IMMUNE AMPLIFIERS IN THERAPEUTIC THERAPY IN CANCER
DE10163399A1 (de) 2001-12-21 2003-07-10 Sustech Gmbh & Co Kg Nanopartikuläre Zubereitung
DE10205332B4 (de) * 2002-02-06 2004-02-12 Berlin Heart Ag Verfahren zur Herstellung von magnetischen Nanoteilchen
JP2006508793A (ja) * 2002-12-09 2006-03-16 イーテーエン ナノヴェイション ゲゼルシャフト ミット ベシュレンクテル ハフツング ナノスケールのコア／シェル粒子およびその製造
AU2003900335A0 (en) * 2003-01-22 2003-02-13 Sirtex Medical Limited Microparticles for selectively targeted hyperthermia
DE10331439B3 (de) 2003-07-10 2005-02-03 Micromod Partikeltechnologie Gmbh Magnetische Nanopartikel mit verbesserten Magneteigenschaften
US20050107870A1 (en) * 2003-04-08 2005-05-19 Xingwu Wang Medical device with multiple coating layers
US20050119725A1 (en) * 2003-04-08 2005-06-02 Xingwu Wang Energetically controlled delivery of biologically active material from an implanted medical device
DE10326538A1 (de) * 2003-06-12 2005-01-05 Institut für Neue Materialien Gemeinnützige GmbH Abriebfeste optische Schichten und Formkörper
DE10344449A1 (de) * 2003-09-25 2005-04-28 Henkel Kgaa Klebstoff-Zusammensetzung mit Barriere-Eigenschaften
US20050090732A1 (en) * 2003-10-28 2005-04-28 Triton Biosystems, Inc. Therapy via targeted delivery of nanoscale particles
DE10359252A1 (de) * 2003-12-17 2005-07-28 Siemens Ag Navigierte Wärmebehandlung von Tumoren mit enzymumhüllten Eisenpartikeln
US20060018835A1 (en) * 2004-04-02 2006-01-26 General Electric Company Nanoparticles with inorganic core and methods of using them
US7407816B2 (en) 2004-05-07 2008-08-05 Gentius, Inc Isoelectric particles and uses thereof
US7842281B2 (en) * 2004-05-10 2010-11-30 The Florida State University Research Foundation Magnetic particle composition for therapeutic hyperthermia
US8728525B2 (en) 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
US20050260137A1 (en) * 2004-05-18 2005-11-24 General Electric Company Contrast agents for magnetic resonance imaging
DE102004038274A1 (de) * 2004-08-06 2006-03-16 Henkel Kgaa Bindemittel mit Barriere-Eigenschaften II
JP5194251B2 (ja) * 2004-08-25 2013-05-08 国立大学法人 鹿児島大学 複合微粒子及びその製造方法
DE102004052533A1 (de) † 2004-10-15 2006-05-04 Mykhaylyk, Olga, Dr. Magnetische Partikel zur Verwendung in Therapie und Diagnostik
DE102005016873A1 (de) 2005-04-12 2006-10-19 Magforce Nanotechnologies Ag Nanopartikel-Wirstoff-Konjugate
EP1883425A1 (en) * 2005-05-23 2008-02-06 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
DE102005039579B4 (de) * 2005-08-19 2022-06-30 Magforce Ag Verfahren zur Einschleusung von therapeutischen Substanzen in Zellen
DE102005060834A1 (de) * 2005-12-20 2007-06-28 Grönemeyer Holding GmbH & Co. KG Magnetfeldapplikator
DE102006007564A1 (de) * 2006-02-16 2007-08-30 Röhm Gmbh Nanoskalige superparamagnetische Poly(meth)acrylatpolymere
US8303931B2 (en) 2006-02-17 2012-11-06 Topass Gmbh Multimodal imaging using a three compartment polymer nanoparticle with cell specificity
WO2007115291A2 (en) * 2006-04-04 2007-10-11 Freedom-2, Inc. Tissue markings with discrete absorption particles
EP1852107A1 (en) * 2006-04-19 2007-11-07 Nanobiotix Magnetic nanoparticles compositions and uses thereof
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
US9277295B2 (en) * 2006-06-16 2016-03-01 Cisco Technology, Inc. Securing media content using interchangeable encryption key
WO2008003641A1 (en) * 2006-07-04 2008-01-10 Bracco Imaging S.P.A. Device for localized thermal ablation of biological tissue, particularly tumoral tissues or the like
CN101500616A (zh) 2006-08-04 2009-08-05 巴克斯特国际公司 预防和/或逆转新发作自身免疫糖尿病的基于微球的组合物
RU2481125C2 (ru) * 2006-12-18 2013-05-10 Колороббия Италия С.П.А. Магнитные наночастицы для применения при гипертермии, их приготовление и применение в магнитных системах для фармакологического использования
US20080167548A1 (en) * 2007-01-04 2008-07-10 Sorensen Alma G Tissue Alteration With MRI RF Field
US20110104073A1 (en) * 2007-01-18 2011-05-05 Qi Zeng Iron/Iron Oxide Nanoparticle and Use Thereof
ES2393639T3 (es) 2007-01-21 2012-12-26 Hemoteq Ag Producto médico para tratar cierres de conductos corporales y prevención de nuevos cierres
US20080281386A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for treating body tissue
US20080281318A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for inductive heat treatment of body tissue
US20090005734A1 (en) * 2007-06-27 2009-01-01 Tessaron Medical, Inc. Systems and methods for delivering particles into patient body
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US20090157069A1 (en) * 2007-12-06 2009-06-18 Curtis Tom Systems and methods for thermal treatment of body tissue
DE102008003615A1 (de) 2008-01-09 2009-07-16 Magforce Nanotechnologies Ag Magnetische Transducer
DE102008008522A1 (de) 2008-02-11 2009-08-13 Magforce Nanotechnologies Ag Implantierbare Nanopartikel-enthaltende Produkte
KR101101832B1 (ko) 2008-05-20 2012-01-05 연세대학교 산학협력단 열방출 나노 물질
US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US8323615B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US8367427B2 (en) 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
DE102008064036B4 (de) * 2008-12-22 2012-06-06 Heraeus Medical Gmbh Polymethylmethacrylat-Knochenzement-Zusammensetzung zur kontrollierten Hyperthermiebehandlung und deren Verwendung
US8685458B2 (en) 2009-03-05 2014-04-01 Bend Research, Inc. Pharmaceutical compositions of dextran polymer derivatives
US8293213B2 (en) * 2009-03-12 2012-10-23 Palo Alto Research Center Incorporated Method and apparatus for thrombus removal using magnetic particles
EP2246376B1 (en) * 2009-04-27 2014-03-05 Leibniz-Institut für Polymerforschung Dresden e.V. Method for preparing particles with a conjugated polymer shell
EP2944332B1 (en) 2009-07-10 2016-08-17 Boston Scientific Scimed, Inc. Use of nanocrystals for a drug delivery balloon
EP2453938B1 (en) * 2009-07-17 2015-08-19 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
US9205155B2 (en) 2009-10-30 2015-12-08 General Electric Company Treating water insoluble nanoparticles with hydrophilic alpha-hydroxyphosphonic acid conjugates, the so modified nanoparticles and their use as contrast agents
US8565892B2 (en) 2009-10-31 2013-10-22 Qteris, Inc. Nanoparticle-sized magnetic absorption enhancers having three-dimensional geometries adapted for improved diagnostics and hyperthermic treatment
US8715150B2 (en) 2009-11-02 2014-05-06 Pulse Therapeutics, Inc. Devices for controlling magnetic nanoparticles to treat fluid obstructions
DE102009058769A1 (de) 2009-12-16 2011-06-22 MagForce Nanotechnologies AG, 10589 Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
US20110160645A1 (en) * 2009-12-31 2011-06-30 Boston Scientific Scimed, Inc. Cryo Activated Drug Delivery and Cutting Balloons
WO2011135397A1 (en) * 2010-04-29 2011-11-03 University Of Calcutta Antiplatelet agent and methods of using the same
US9669200B2 (en) 2010-08-06 2017-06-06 Boston Scientific Scimed, Inc. Systems and methods for the treatment of pelvic disorders including magnetic particulates
EP2611476B1 (en) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
US8815294B2 (en) 2010-09-03 2014-08-26 Bend Research, Inc. Pharmaceutical compositions of dextran polymer derivatives and a carrier material
KR101173867B1 (ko) 2010-10-28 2012-08-14 삼성에스디아이 주식회사 리튬 이차 전지
US9180172B2 (en) 2010-12-15 2015-11-10 Ams Research Corporation Treatment of Peyronies disease
US8979797B2 (en) 2010-12-16 2015-03-17 Ams Research Corporation High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics
KR20140022904A (ko) 2011-04-20 2014-02-25 유니버시티 오브 시드니 치료방법 및 그에 사용가능한 제제
US9060938B2 (en) 2011-05-10 2015-06-23 Bend Research, Inc. Pharmaceutical compositions of active agents and cationic dextran polymer derivatives
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
AU2012292554B2 (en) 2011-08-10 2014-10-30 Nanotherm Therapeutics GmbH Agglomerating magnetic alkoxysilane-coated nanoparticles
WO2013021039A1 (en) 2011-08-11 2013-02-14 Basf Se Microwave absorbing composition
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
EA029635B1 (ru) 2011-12-16 2018-04-30 Нанобиотикс Применение наночастицы, включающей металлический материал, покрытый материалом оксида гафния, в онкологии и композиция, ее содержащая
EP2813546A4 (en) * 2012-02-07 2015-09-16 Univ Tsukuba HYBRID ORGANIC-INORGANIC COMPLEX OF A HIGH-MOLECULAR NITROXIDE COMPOUND AND INORGANIC PARTICLE
US9883878B2 (en) 2012-05-15 2018-02-06 Pulse Therapeutics, Inc. Magnetic-based systems and methods for manipulation of magnetic particles
WO2014008378A1 (en) * 2012-07-06 2014-01-09 Mtd Products Inc Drive sprocket for a tracked utility vehicle
US9884662B2 (en) 2013-09-13 2018-02-06 Mtd Products Inc Suspension and lock-out systems for a partially tracked vehicle
WO2015038913A1 (en) 2013-09-13 2015-03-19 Mtd Products Inc Drive sprocket for a tracked vehicle
WO2015056960A1 (ko) 2013-10-16 2015-04-23 주식회사 지니스 전자기파를 이용한 암 온열치료용 감작제 조성물 및 이를 이용한 암 치료 방법
US9902441B2 (en) 2014-08-21 2018-02-27 Mtd Products Inc Track drive
UA124572C2 (uk) 2015-05-28 2021-10-13 Нанобіотікс Наночастинки для застосування як терапевтичної вакцини
CA2987107A1 (en) 2015-05-29 2016-12-08 Mtd Products Inc Utility vehicle
JP6517362B2 (ja) * 2015-06-15 2019-05-22 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 治療的加熱処理のための装置および方法
DE102016006320A1 (de) 2016-05-25 2017-11-30 Carl Freudenberg Kg Fixierbare Flächengebilde
JP7051483B2 (ja) * 2017-03-29 2022-04-11 三洋化成工業株式会社 マイクロ波加熱溶着用樹脂組成物
US11511818B2 (en) 2017-09-05 2022-11-29 Mtd Products Inc Track drive
EP3691438B1 (en) 2017-10-06 2023-06-14 MTD Products Inc High-efficiency lawn maintenance tool and high-efficiency cutting blade
US11918315B2 (en) 2018-05-03 2024-03-05 Pulse Therapeutics, Inc. Determination of structure and traversal of occlusions using magnetic particles
US12171443B1 (en) 2021-03-09 2024-12-24 Pulse Therapeutics, Inc. Magnetically controlled flow generation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4827945A (en) * 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
FR2618084B1 (fr) * 1987-07-15 1989-11-10 Rhone Poulenc Chimie Microspheres magnetisables a base de polysiloxane, leur procede de preparation et leur application en biologie
ATE139431T1 (de) * 1988-08-04 1996-07-15 Advanced Magnetics Inc Von einem rezeptor induziertes kontrastmittel für den endocytose-typ mri
US5460831A (en) * 1990-06-22 1995-10-24 The Regents Of The University Of California Targeted transfection nanoparticles
US5462751A (en) * 1990-06-22 1995-10-31 The Regeants Of The University Of California Biological and pharmaceutical agents having a nanomeric biodegradable core
DE4026978A1 (de) * 1990-08-25 1992-02-27 Bayer Ag Auf traegern angebrachte ein- oder mehrlagige schichtelemente und ihre herstellung
US5616311A (en) * 1991-01-15 1997-04-01 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
AU4402793A (en) * 1992-05-29 1993-12-30 Regents Of The University Of California, The Coated transplant and method for making same
DE69332082T2 (de) * 1992-11-06 2003-02-06 Hisamitsu Pharmaceutical Co., Inc. Perorale pharmazeutische zubereitung mit freisetzung im unteren verfdauungstrakt
US5547748A (en) * 1994-01-14 1996-08-20 Sri International Carbon nanoencapsulates
US6103379A (en) * 1994-10-06 2000-08-15 Bar-Ilan University Process for the preparation of microspheres and microspheres made thereby
GB9420390D0 (en) * 1994-10-10 1994-11-23 Nycomed Salutar Inc Liposomal agents
US6022500A (en) * 1995-09-27 2000-02-08 The United States Of America As Represented By The Secretary Of The Army Polymer encapsulation and polymer microsphere composites
DE19614136A1 (de) * 1996-04-10 1997-10-16 Inst Neue Mat Gemein Gmbh Verfahren zur Herstellung agglomeratfreier nanoskaliger Eisenoxidteilchen mit hydrolysebeständigem Überzug
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2320837A1 (es) * 2007-07-26 2009-05-28 Consejo Superior De Investigaciones Cientificas Dispositivo de hipertermia y su utilizacion con nanoparticulas.
ES2320837B1 (es) * 2007-07-26 2010-03-04 Consejo Superior De Investigaciones Cientificas Dispositivo de hipertermia y su utilizacion con nanoparticulas.

Also Published As

Publication number Publication date
ATE223731T1 (de) 2002-09-15
DE59805535D1 (de) 2002-10-17
EP1001811B1 (de) 2002-09-11
JP5116743B2 (ja) 2013-01-09
PT1001811E (pt) 2003-01-31
JP2010001308A (ja) 2010-01-07
WO1998058673A1 (de) 1998-12-30
CN1211127C (zh) 2005-07-20
DE19726282A1 (de) 1998-12-24
JP4902900B2 (ja) 2012-03-21
US6979466B2 (en) 2005-12-27
EP1001811A1 (de) 2000-05-24
DK1001811T3 (da) 2003-01-20
CN1260724A (zh) 2000-07-19
JP2002507964A (ja) 2002-03-12
US20030180370A1 (en) 2003-09-25
US6541039B1 (en) 2003-04-01

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