ES2180632T3 - Activador de tiol estable en un liquido. - Google Patents
Activador de tiol estable en un liquido.Info
- Publication number
- ES2180632T3 ES2180632T3 ES95918415T ES95918415T ES2180632T3 ES 2180632 T3 ES2180632 T3 ES 2180632T3 ES 95918415 T ES95918415 T ES 95918415T ES 95918415 T ES95918415 T ES 95918415T ES 2180632 T3 ES2180632 T3 ES 2180632T3
- Authority
- ES
- Spain
- Prior art keywords
- activator
- solution
- liquid
- stable
- tiol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/50—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving creatine phosphokinase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
SE PRESENTA UNA SOLUCION ACTIVADORA DE TIOL ESTABLE EN LIQUIDO, ACUOSA. LA SOLUCION PUEDE COMPRENDER UN ACTIVADOR DE TIOL, TAL COMO N-ACETIL-LCISTEINA Y UN AGENTE ESTABILIZANTE, TAL COMO MANITOL. EL TIOL SE ESTABILIZA EN LA SOLUCION ACUOSA DURANTE AL MENOS UN AÑO BAJO CONDICIONES DE ALMACENAMIENTO Y DURANTE AL MENOS 28 DIAS BAJO CONDICIONES DE BOTELLA ABIERTA. LA SOLUCION PUEDE USARSE COMO UN REACTIVADOR DE ACTIVIDAD CATALITICA QUE QUINASA DE CREATINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23926094A | 1994-05-06 | 1994-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2180632T3 true ES2180632T3 (es) | 2003-02-16 |
Family
ID=22901361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95918415T Expired - Lifetime ES2180632T3 (es) | 1994-05-06 | 1995-05-05 | Activador de tiol estable en un liquido. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5700653A (es) |
EP (1) | EP0707658B1 (es) |
JP (1) | JP3619865B2 (es) |
AT (1) | ATE221919T1 (es) |
AU (1) | AU692547B2 (es) |
CA (1) | CA2165808A1 (es) |
DE (1) | DE69527686T2 (es) |
ES (1) | ES2180632T3 (es) |
WO (1) | WO1995030769A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19755079A1 (de) | 1997-12-11 | 1999-06-17 | Roche Diagnostics Gmbh | Stabilisiertes Reagenz und Verfahren zur Bestimmung von Creatin-Kinase |
US5908864A (en) * | 1998-05-28 | 1999-06-01 | Dymatize Enterprises | Creatine gel |
EP1013774B8 (de) | 1998-12-22 | 2006-12-06 | Olympus Life and Material Science Europa GmbH | Flüssigreagenz für den Nachweis von Kreatinkinase |
WO2000040746A1 (en) * | 1999-01-08 | 2000-07-13 | Medical Analysis Systems, Inc. | Compositions and methods for stabilizing thiol-containing biomolecules |
US20060020035A1 (en) * | 2004-03-11 | 2006-01-26 | Oregon Health & Science University | Bone marrow protection with N-acetyl-L-cysteine |
US8148356B2 (en) * | 2005-08-24 | 2012-04-03 | Cumberland Pharmaceuticals, Inc. | Acetylcysteine composition and uses therefor |
AU2011202871B2 (en) * | 2005-08-24 | 2014-06-12 | Cumberland Pharmaceuticals Inc. | Acetylcysteine composition and uses therefor |
JP5468299B2 (ja) * | 2009-05-15 | 2014-04-09 | 旭化成ファーマ株式会社 | Impdh含有組成物及びimpdhの安定化方法 |
EP2544663B1 (en) * | 2010-03-12 | 2018-01-03 | Berg LLC | Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof |
MY183615A (en) | 2011-06-17 | 2021-03-03 | Berg Llc | Inhalable pharmaceutical compositions |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2648759C3 (de) * | 1976-10-27 | 1979-05-31 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisierungsmittel für Enzyme |
US4339533A (en) * | 1980-07-30 | 1982-07-13 | Technicon Instruments Corporation | Stabilization of creatine kinase (CK) and its application as a reference standard |
US4883762A (en) * | 1983-06-06 | 1989-11-28 | Ciba Corning Diagnostics Corp. | Stabilized isoenzyme control products |
JPS6188899A (ja) * | 1984-10-05 | 1986-05-07 | Unitika Ltd | クレアチンキナ−ゼ定量用試薬 |
JPS62104598A (ja) * | 1985-11-01 | 1987-05-15 | Yatoron:Kk | クレアチンキナ−ゼ測定用試薬 |
FR2610626B1 (fr) * | 1987-02-09 | 1989-05-19 | Oreal | Nouveau systeme anti-oxydant a base d'un ester d'ascorbyle stabilise, contenant en association au moins un agent complexant et au moins un thiol, et compositions contenant un tel systeme anti-oxydant |
JPS63283600A (ja) * | 1987-05-18 | 1988-11-21 | Fuji Photo Film Co Ltd | クレアチンキナ−ゼ活性測定用分析要素 |
JPH0690202B2 (ja) * | 1988-04-06 | 1994-11-14 | ユニチカ株式会社 | クレアチンキナーゼ活性測定用試薬およびそれを用いる測定方法 |
CA2028593C (en) * | 1989-10-31 | 2007-08-21 | Douglas R. Brandt | Stabilized enzyme compositions |
IT1242642B (it) * | 1990-04-17 | 1994-05-16 | Alfa Wassermann Spa | Formulazioni iniettabili contenenti naproxen sale sodico. |
US5192657A (en) * | 1990-12-18 | 1993-03-09 | Ortho Diagnostic Systems, Inc. | Stabilized proteolytic solution and reagent kit |
JPH05111396A (ja) * | 1991-07-17 | 1993-05-07 | Oriental Yeast Co Ltd | クレアチンキナ−ゼの活性測定方法 およびそれに用いる試薬 |
US5298406A (en) * | 1992-09-14 | 1994-03-29 | E. I. Du Pont De Nemours And Company | Formulation for stabilizing enzymatic activity and immunoreactivity of creatine kinase and creatine kinase isoenzymes |
-
1995
- 1995-05-05 DE DE69527686T patent/DE69527686T2/de not_active Expired - Fee Related
- 1995-05-05 CA CA002165808A patent/CA2165808A1/en not_active Abandoned
- 1995-05-05 EP EP95918415A patent/EP0707658B1/en not_active Expired - Lifetime
- 1995-05-05 AT AT95918415T patent/ATE221919T1/de not_active IP Right Cessation
- 1995-05-05 JP JP52915095A patent/JP3619865B2/ja not_active Expired - Fee Related
- 1995-05-05 ES ES95918415T patent/ES2180632T3/es not_active Expired - Lifetime
- 1995-05-05 WO PCT/US1995/005702 patent/WO1995030769A1/en active IP Right Grant
- 1995-05-05 AU AU24367/95A patent/AU692547B2/en not_active Ceased
- 1995-10-09 US US08/541,473 patent/US5700653A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP3619865B2 (ja) | 2005-02-16 |
WO1995030769A1 (en) | 1995-11-16 |
CA2165808A1 (en) | 1995-11-16 |
US5700653A (en) | 1997-12-23 |
JPH09500027A (ja) | 1997-01-07 |
AU2436795A (en) | 1995-11-29 |
EP0707658B1 (en) | 2002-08-07 |
DE69527686T2 (de) | 2003-04-03 |
AU692547B2 (en) | 1998-06-11 |
DE69527686D1 (de) | 2002-09-12 |
EP0707658A1 (en) | 1996-04-24 |
ATE221919T1 (de) | 2002-08-15 |
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