ES2180632T3 - Activador de tiol estable en un liquido. - Google Patents

Activador de tiol estable en un liquido.

Info

Publication number
ES2180632T3
ES2180632T3 ES95918415T ES95918415T ES2180632T3 ES 2180632 T3 ES2180632 T3 ES 2180632T3 ES 95918415 T ES95918415 T ES 95918415T ES 95918415 T ES95918415 T ES 95918415T ES 2180632 T3 ES2180632 T3 ES 2180632T3
Authority
ES
Spain
Prior art keywords
activator
solution
liquid
stable
tiol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95918415T
Other languages
English (en)
Inventor
Carrie J Lu
Frederick S Yein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of ES2180632T3 publication Critical patent/ES2180632T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/50—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving creatine phosphokinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE PRESENTA UNA SOLUCION ACTIVADORA DE TIOL ESTABLE EN LIQUIDO, ACUOSA. LA SOLUCION PUEDE COMPRENDER UN ACTIVADOR DE TIOL, TAL COMO N-ACETIL-LCISTEINA Y UN AGENTE ESTABILIZANTE, TAL COMO MANITOL. EL TIOL SE ESTABILIZA EN LA SOLUCION ACUOSA DURANTE AL MENOS UN AÑO BAJO CONDICIONES DE ALMACENAMIENTO Y DURANTE AL MENOS 28 DIAS BAJO CONDICIONES DE BOTELLA ABIERTA. LA SOLUCION PUEDE USARSE COMO UN REACTIVADOR DE ACTIVIDAD CATALITICA QUE QUINASA DE CREATINA.
ES95918415T 1994-05-06 1995-05-05 Activador de tiol estable en un liquido. Expired - Lifetime ES2180632T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23926094A 1994-05-06 1994-05-06

Publications (1)

Publication Number Publication Date
ES2180632T3 true ES2180632T3 (es) 2003-02-16

Family

ID=22901361

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95918415T Expired - Lifetime ES2180632T3 (es) 1994-05-06 1995-05-05 Activador de tiol estable en un liquido.

Country Status (9)

Country Link
US (1) US5700653A (es)
EP (1) EP0707658B1 (es)
JP (1) JP3619865B2 (es)
AT (1) ATE221919T1 (es)
AU (1) AU692547B2 (es)
CA (1) CA2165808A1 (es)
DE (1) DE69527686T2 (es)
ES (1) ES2180632T3 (es)
WO (1) WO1995030769A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19755079A1 (de) 1997-12-11 1999-06-17 Roche Diagnostics Gmbh Stabilisiertes Reagenz und Verfahren zur Bestimmung von Creatin-Kinase
US5908864A (en) * 1998-05-28 1999-06-01 Dymatize Enterprises Creatine gel
EP1013774B8 (de) 1998-12-22 2006-12-06 Olympus Life and Material Science Europa GmbH Flüssigreagenz für den Nachweis von Kreatinkinase
WO2000040746A1 (en) * 1999-01-08 2000-07-13 Medical Analysis Systems, Inc. Compositions and methods for stabilizing thiol-containing biomolecules
US20060020035A1 (en) * 2004-03-11 2006-01-26 Oregon Health & Science University Bone marrow protection with N-acetyl-L-cysteine
US8148356B2 (en) * 2005-08-24 2012-04-03 Cumberland Pharmaceuticals, Inc. Acetylcysteine composition and uses therefor
AU2011202871B2 (en) * 2005-08-24 2014-06-12 Cumberland Pharmaceuticals Inc. Acetylcysteine composition and uses therefor
JP5468299B2 (ja) * 2009-05-15 2014-04-09 旭化成ファーマ株式会社 Ｉｍｐｄｈ含有組成物及びｉｍｐｄｈの安定化方法
PT2544663T (pt) * 2010-03-12 2018-04-05 Berg Llc Formulações intravenosas de coenzima q10 (coq10) e métodos de uso da mesma
AU2012271274B2 (en) 2011-06-17 2017-07-27 Berg Llc Inhalable pharmaceutical compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2648759C3 (de) * 1976-10-27 1979-05-31 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisierungsmittel für Enzyme
US4339533A (en) * 1980-07-30 1982-07-13 Technicon Instruments Corporation Stabilization of creatine kinase (CK) and its application as a reference standard
US4883762A (en) * 1983-06-06 1989-11-28 Ciba Corning Diagnostics Corp. Stabilized isoenzyme control products
JPS6188899A (ja) * 1984-10-05 1986-05-07 Unitika Ltd クレアチンキナ−ゼ定量用試薬
JPS62104598A (ja) * 1985-11-01 1987-05-15 Yatoron:Kk クレアチンキナ−ゼ測定用試薬
FR2610626B1 (fr) * 1987-02-09 1989-05-19 Oreal Nouveau systeme anti-oxydant a base d'un ester d'ascorbyle stabilise, contenant en association au moins un agent complexant et au moins un thiol, et compositions contenant un tel systeme anti-oxydant
JPS63283600A (ja) * 1987-05-18 1988-11-21 Fuji Photo Film Co Ltd クレアチンキナ−ゼ活性測定用分析要素
JPH0690202B2 (ja) * 1988-04-06 1994-11-14 ユニチカ株式会社 クレアチンキナーゼ活性測定用試薬およびそれを用いる測定方法
CA2028593C (en) * 1989-10-31 2007-08-21 Douglas R. Brandt Stabilized enzyme compositions
IT1242642B (it) * 1990-04-17 1994-05-16 Alfa Wassermann Spa Formulazioni iniettabili contenenti naproxen sale sodico.
US5192657A (en) * 1990-12-18 1993-03-09 Ortho Diagnostic Systems, Inc. Stabilized proteolytic solution and reagent kit
JPH05111396A (ja) * 1991-07-17 1993-05-07 Oriental Yeast Co Ltd クレアチンキナ−ゼの活性測定方法 およびそれに用いる試薬
US5298406A (en) * 1992-09-14 1994-03-29 E. I. Du Pont De Nemours And Company Formulation for stabilizing enzymatic activity and immunoreactivity of creatine kinase and creatine kinase isoenzymes

Also Published As

Publication number Publication date
DE69527686D1 (de) 2002-09-12
WO1995030769A1 (en) 1995-11-16
EP0707658A1 (en) 1996-04-24
ATE221919T1 (de) 2002-08-15
AU2436795A (en) 1995-11-29
AU692547B2 (en) 1998-06-11
JP3619865B2 (ja) 2005-02-16
US5700653A (en) 1997-12-23
EP0707658B1 (en) 2002-08-07
DE69527686T2 (de) 2003-04-03
CA2165808A1 (en) 1995-11-16
JPH09500027A (ja) 1997-01-07

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