ES2179075T3 - Preparaciones que contienen dioxido de silicio para mejorar su sabor. - Google Patents

Preparaciones que contienen dioxido de silicio para mejorar su sabor.

Info

Publication number
ES2179075T3
ES2179075T3 ES94917447T ES94917447T ES2179075T3 ES 2179075 T3 ES2179075 T3 ES 2179075T3 ES 94917447 T ES94917447 T ES 94917447T ES 94917447 T ES94917447 T ES 94917447T ES 2179075 T3 ES2179075 T3 ES 2179075T3
Authority
ES
Spain
Prior art keywords
taste
flavor
improve
silicon dioxide
containing silicon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94917447T
Other languages
English (en)
Inventor
Stanley Lech
Alexander M Schobel
John Denick Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of ES2179075T3 publication Critical patent/ES2179075T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UNA PREPARACION FRIA/SINUS MASCABLE QUE CONSTA DE UNA MEZCLA DE SABOR AMARGO DE UN DESCONGESTIONANTE, TAL COMO PSEUDOEFEDRINA, Y UN ANTIHISTAMINICO, TAL COMO MALEATO DE DIFENHIDRAMINA Y/O CLORFENIRAMINA QUE NO CONTIENE UNA SENSACION BUCAL DESAGRADABLE NI SABOR METALICO AMARGO, ADSORBIENDO LA MEZCLA DE MEDICAMENTO ACTIVO UTILIZANDO UN PROCESO DE GRANULACION HUMEDO SOBRE UN PORTADOR DE DIOXIDO DE SILICONA QUE CONTIENE DE APROXIMADAMENTE 50 A 85% DEL PESO TOTAL DE LA COMPOSICION ADSORBENTE. SE PREPARA UNA FORMULA DE ALIVIO REALMENTE MULTISINTOMAS MEDIANTE LA ADICION OPCIONAL DE UN ANTITUSIVO COMO UN HIDROBROMURO DE DEXTROMETORFAN Y/O UN ANALGESICO TAL COMO UN ACIDO MECLOFENANICO, ASPIRINA O IBUPROFEN. SE AÑADEN EXCIPIENTES ADICIONALES TALES COMO SABORES, EDULCORANTES, LUBRICANTES Y RELLENOS DE VOLUMEN PARA UN MEJOR SABOR, SENSACION BUCAL MEJORADA Y COMO AYUDA AL PROCESO DE TABLETACION.
ES94917447T 1993-06-04 1994-05-19 Preparaciones que contienen dioxido de silicio para mejorar su sabor. Expired - Lifetime ES2179075T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7262393A 1993-06-04 1993-06-04

Publications (1)

Publication Number Publication Date
ES2179075T3 true ES2179075T3 (es) 2003-01-16

Family

ID=22108786

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94917447T Expired - Lifetime ES2179075T3 (es) 1993-06-04 1994-05-19 Preparaciones que contienen dioxido de silicio para mejorar su sabor.

Country Status (10)

Country Link
US (1) US5681577A (es)
EP (2) EP0701434B1 (es)
JP (1) JP3733140B2 (es)
AU (1) AU681672B2 (es)
CA (1) CA2160368A1 (es)
DE (1) DE69431153T2 (es)
DK (1) DK0701434T3 (es)
ES (1) ES2179075T3 (es)
NZ (1) NZ267002A (es)
WO (1) WO1994028870A1 (es)

Families Citing this family (47)

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EP0701434B1 (en) * 1993-06-04 2002-08-07 Warner-Lambert Company Preparations containing silicon dioxide to improve the taste thereof
MX9807594A (en) * 1996-04-10 1999-03-31 Warner Lambert Co Denaturants for sympathomimetic amine salts
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US20060029653A1 (en) 1997-01-29 2006-02-09 Cronk Peter J Therapeutic delivery system
US6769428B2 (en) 1997-01-29 2004-08-03 Peter J. Cronk Adhesively applied external nasal strips and dilators containing medications and fragrances
US6550474B1 (en) 1997-01-29 2003-04-22 Cns, Inc. Microencapsulated fragrances and methods of coating microcapsules
DE19740983A1 (de) 1997-09-18 1999-04-08 Warner Lambert Co N D Ges D St Verfahren zur Erschwerung der Extraktion von Wirkstoffen aus Tabletten
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US6090403A (en) * 1998-08-17 2000-07-18 Lectec Corporation Inhalation therapy decongestant with foraminous carrier
GT199900148A (es) 1998-09-10 2001-02-28 Desnaturalizantes para las sales aminas simpaticomimeticas.
US6485747B1 (en) * 1998-10-30 2002-11-26 Monsanto Company Coated active tablet(s)
US6231838B1 (en) 1999-12-15 2001-05-15 American Home Products Corporation Taste masking with silicon dioxide
JP2002138034A (ja) * 2000-10-27 2002-05-14 Kyoto Pharmaceutical Industries Ltd 苦味マスキングチュアブル錠およびその製造方法
WO2002036077A2 (en) * 2000-11-06 2002-05-10 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
ES2190730B1 (es) * 2001-06-11 2004-12-01 Farmalider, S.A. Composicion farmaceutica para tratar la congestion nasal via sistemica.
US20050143471A1 (en) * 2001-10-22 2005-06-30 Shen Gao Taste masking spill-resistant formulation
US20030235618A1 (en) * 2001-10-22 2003-12-25 Taro Pharmaceutical Industries Ltd. Taste masking spill-resistant formulation
US20040137052A1 (en) * 2001-12-25 2004-07-15 Yoshihiro Uchiyama Acid-containing preparations
AU2003221326A1 (en) * 2002-03-06 2003-09-16 Kyowa Hakko Kogyo Co., Ltd. Tablets quickly disintegrating in oral cavity
JP4320217B2 (ja) * 2002-07-10 2009-08-26 剤盛堂薬品株式会社 鼻炎用経口製剤
KR20060004646A (ko) * 2002-08-14 2006-01-12 이 아이 듀폰 디 네모아 앤드 캄파니 고 액체 부하량을 가진 유동성 고상 분말
JP2004107258A (ja) * 2002-09-18 2004-04-08 Ss Pharmaceut Co Ltd 催眠用圧縮成型製剤
US8092831B2 (en) * 2002-11-08 2012-01-10 Andrx Pharmaceuticals, Llc Antihistamine and decongestant system
US7863287B2 (en) * 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
US6979689B2 (en) * 2002-12-20 2005-12-27 Pediamed Pharmaceuticals, Inc. Compositions and methods for treating upper respiratory congestion
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
US20070003622A1 (en) * 2004-12-16 2007-01-04 Sovereign Pharmaceuticals, Ltd. Diphenhydramine containing dosage form
US9592197B2 (en) * 2004-12-16 2017-03-14 Sovereign Pharmaceuticals, Llc Dosage form containing diphenhydramine and another drug
US7529255B2 (en) * 2005-04-21 2009-05-05 Microsoft Corporation Peer-to-peer multicasting using multiple transport protocols
BRPI0620578A2 (pt) 2005-12-27 2011-12-06 Jubilant Organosys Ltd composição farmacêutica que dissolve na boca e processo para o preparo da mesma
US9238073B2 (en) * 2006-04-12 2016-01-19 Wyeth Llc Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive
US20080015241A1 (en) * 2006-07-13 2008-01-17 Cornerstone Biopharma, Inc. All day rhinitic condition treatment regimen
US20080311196A1 (en) * 2006-07-13 2008-12-18 White Donna F All Day Rhinitic Condition Treatment Regimen
US9005652B2 (en) * 2006-07-25 2015-04-14 Wyeth Chewable tablet containing phenylephrine
MX2009002195A (es) 2006-08-30 2009-05-28 David William Smith Metodo para impartir una rigidez mono-axial o multi-axial a materiales extruidos y productos que resultan de los mismos.
US8653135B1 (en) * 2007-02-07 2014-02-18 Sovereign Pharmaceuticals, Llc Alternating sympathomimetic therapy for the treatment of respiratory aliments
US8212036B2 (en) 2007-12-19 2012-07-03 Sunovion Pharmaceuticals Inc. Maleate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
US8198277B2 (en) 2007-12-19 2012-06-12 Sunovion Pharmaceuticals Inc. L-malate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
US8198278B2 (en) 2007-12-19 2012-06-12 Sunovion Pharmaceuticals Inc. Besylate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
US8268832B2 (en) 2007-12-19 2012-09-18 Sunovion Pharmaceuticals Inc. Maleate salts of 6-(5-chloro-2-Pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
US8269005B2 (en) 2007-12-19 2012-09-18 Sunovion Pharmaceuticals Inc. L-malate salts of 6-(5-chloro-2-Pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-Oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
US7914828B2 (en) * 2008-10-17 2011-03-29 Levine Brian M Combination herbal product to benefit respiratory tract
US8361519B2 (en) 2010-11-18 2013-01-29 Aadvantics Pharmaceuticals, Inc. Combination herbal product to benefit respiratory tract in people exposed to smoke
CN106491545A (zh) * 2016-09-22 2017-03-15 万特制药(海南)有限公司 盐酸氟西汀口崩片及其制备方法
AU2017331369B2 (en) * 2016-09-26 2019-11-21 The Procter & Gamble Company Extended relief dosage form

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Also Published As

Publication number Publication date
DE69431153D1 (de) 2002-09-12
EP0701434A1 (en) 1996-03-20
JPH08511524A (ja) 1996-12-03
DK0701434T3 (da) 2002-11-18
CA2160368A1 (en) 1994-12-22
AU681672B2 (en) 1997-09-04
DE69431153T2 (de) 2003-03-13
NZ267002A (en) 1997-07-27
EP1166801A1 (en) 2002-01-02
WO1994028870A1 (en) 1994-12-22
US5681577A (en) 1997-10-28
EP0701434B1 (en) 2002-08-07
AU6916794A (en) 1995-01-03
JP3733140B2 (ja) 2006-01-11

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