ES2178786T3 - Uso de aminoalcoholes de bajo peso molecular en composiciones oftalmicos. - Google Patents
Uso de aminoalcoholes de bajo peso molecular en composiciones oftalmicos.Info
- Publication number
- ES2178786T3 ES2178786T3 ES97947519T ES97947519T ES2178786T3 ES 2178786 T3 ES2178786 T3 ES 2178786T3 ES 97947519 T ES97947519 T ES 97947519T ES 97947519 T ES97947519 T ES 97947519T ES 2178786 T3 ES2178786 T3 ES 2178786T3
- Authority
- ES
- Spain
- Prior art keywords
- molecular weight
- low molecular
- compositions
- aminoalcoholes
- ophthalm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/147—Alcohols or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Eyeglasses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE AL USO DE AMINOALCOHOLES DE BAJO PESO MOLECULAR EN UNAS COMPOSICIONES OFTALMICAS. DICHOS COMPUESTOS PERMITEN INCREMENTAR LA EFICACIA DE AGENTES CONSERVADORES ANTIMICROBIANOS. LOS AMINOALCOHOLES PREFERIDOS CONSISTEN EN 2 - AMINO - 2 - METILO - 1 - PROPANOL (AMP), EN 2 DIMETILAMINO - 2 - METILO - 1 - PROPANEDIOL (DMAMP), EN 2 AMINO - 2 - ETILO - 1,3 - PROPANEDIOL (AEPD), EN 2 - AMINO - 2 METILO 1 - PROPANIDIOL (AMPD), Y FINALMENTE EN 2 - AMINO - 1 BUTANOL (AB). ESTAS COMPOSICIONES OFTALMICAS PUEDEN ADEMAS COMPRENDER UN OCASIONAL SISTEMA TAMPON BORATO/POLIOL ASI COMO UNA ALQUILAMINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3307996P | 1996-12-13 | 1996-12-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2178786T3 true ES2178786T3 (es) | 2003-01-01 |
Family
ID=21868442
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES01204124T Expired - Lifetime ES2262603T3 (es) | 1996-12-13 | 1997-11-17 | Composiciones oftalmicas que comprenden aminoalcoholes. |
ES97947519T Expired - Lifetime ES2178786T3 (es) | 1996-12-13 | 1997-11-17 | Uso de aminoalcoholes de bajo peso molecular en composiciones oftalmicos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES01204124T Expired - Lifetime ES2262603T3 (es) | 1996-12-13 | 1997-11-17 | Composiciones oftalmicas que comprenden aminoalcoholes. |
Country Status (15)
Country | Link |
---|---|
US (5) | US6319464B1 (es) |
EP (1) | EP0948357B1 (es) |
JP (2) | JP3724813B2 (es) |
KR (1) | KR100366676B1 (es) |
CN (1) | CN1157227C (es) |
AT (2) | ATE326983T1 (es) |
AU (1) | AU718199B2 (es) |
CA (1) | CA2272308C (es) |
DE (2) | DE69735963T2 (es) |
DK (1) | DK0948357T3 (es) |
ES (2) | ES2262603T3 (es) |
HK (1) | HK1022089A1 (es) |
NZ (1) | NZ336031A (es) |
PT (2) | PT1190718E (es) |
WO (1) | WO1998025649A1 (es) |
Families Citing this family (47)
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---|---|---|---|---|
EP0948357B1 (en) * | 1996-12-13 | 2002-06-12 | Alcon Laboratories, Inc. | Use of low molecular weight amino alcohols in ophthalmic compositions |
US6730065B1 (en) * | 2000-09-15 | 2004-05-04 | Ocularis Pharma, Inc. | Night vision composition |
US20020082288A1 (en) * | 1999-09-16 | 2002-06-27 | Gerald Horn | Ophthalmic formulations comprising an imidazoline |
US8889112B2 (en) * | 1999-09-16 | 2014-11-18 | Ocularis Pharma, Llc | Ophthalmic formulations including selective alpha 1 antagonists |
US20020039975A1 (en) * | 2000-07-31 | 2002-04-04 | Stone Ralph P. | Simplified process for cleaning and disinfecting contact lenses with a single solution |
US20060211753A1 (en) * | 2000-11-03 | 2006-09-21 | Ocularis Pharma, Inc. | Method and composition which reduces stimulation of muscles which dilate the eye |
DE10106230A1 (de) * | 2001-02-10 | 2002-08-14 | Creavis Tech & Innovation Gmbh | Verfahren zur Herstellung mikrobizider Oberflächen durch Immobilisierung von Aminoalkoholen |
EP1455804A4 (en) * | 2001-12-21 | 2005-01-05 | Alcon Inc | USE OF NANOTEILES AS CARRIERS OF BIOCIDES IN OPHTHALMIC COMPOSITIONS |
KR20040073503A (ko) * | 2001-12-21 | 2004-08-19 | 알콘, 인코퍼레이티드 | 안과용 및 이과용 약제학적 조성물의 점도 및 기타물리학적 성질을 개질시키기 위한 무기 나노입자의 용도 |
BR0215238A (pt) * | 2001-12-21 | 2005-05-31 | Alcon Inc | Uso de nanopartìculas inor ânicas sintéticas como veìculos para drogas oftálmicas e óticas |
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US20040115160A1 (en) * | 2002-12-13 | 2004-06-17 | Salamone Joseph C. | Quaternary ammonium esters for disinfection and preservation |
TWI322828B (en) * | 2002-12-23 | 2010-04-01 | Alcon Inc | Use of multifunctional surface active agents to clean contact lenses |
US20040185028A1 (en) * | 2003-03-19 | 2004-09-23 | Zhenze Hu | Antimicrobial compositions containing ethanolamine buffer and biguanide disinfectant |
WO2005018693A1 (ja) * | 2003-08-20 | 2005-03-03 | Menicon Co., Ltd. | コンタクトレンズ用液剤 |
US6936640B2 (en) * | 2003-12-04 | 2005-08-30 | Alcon, Inc. | Biguanide/quaternary ammonium containing copolymeric biocides and use thereof in pharmaceutical compositions |
US7445771B2 (en) * | 2003-12-09 | 2008-11-04 | Alcon, Inc. | Use of bis-amines to enhance the antimicrobial activity of aqueous compositions |
AU2004305535A1 (en) * | 2003-12-09 | 2005-07-07 | Alcon, Inc. | Use of organic buffering agents to enhance the antimicrobial activity of pharmaceutical compositions |
US7022740B2 (en) * | 2004-04-29 | 2006-04-04 | Leonard Mackles | Lubricious ophthalmic solutions |
US20060047005A1 (en) * | 2004-08-26 | 2006-03-02 | Salamone Joseph C | Compositions containing N,N,N',N'-tetrakis(hydroxyalkyl)diamine-or N,N,N',N'-tetrakis(hydroxyalkoxy)diamine-based buffers |
US7629386B2 (en) * | 2004-08-26 | 2009-12-08 | Bausch + Lomb Incorporated | Compositions containing trialkanolamine alkoxylate buffer |
US20060141059A1 (en) * | 2004-12-27 | 2006-06-29 | Alcon, Inc. | Self-preserved ophthalmic pharmaceutical compositions containing tobramycin |
JP5108234B2 (ja) * | 2005-02-07 | 2012-12-26 | 日本特殊陶業株式会社 | マイクロヒータ及びセンサ |
US20060229219A1 (en) * | 2005-04-11 | 2006-10-12 | Advanced Medical Optics, Inc. | Borate-polyol mixtures as a buffering system |
US20070053948A1 (en) * | 2005-09-08 | 2007-03-08 | Bausch & Lomb Incorporated | Lens care solution demonstration kit |
US8071345B2 (en) * | 2006-03-31 | 2011-12-06 | Novozymes A/S | Stabilized subtilisin composition |
US20070287752A1 (en) * | 2006-06-08 | 2007-12-13 | Burke Susan E | Ophthalmic Compositions Comprising A Branched, Glycerol Compound |
TWI394564B (zh) * | 2006-09-21 | 2013-05-01 | Alcon Res Ltd | 自行保存型水性藥學組成物 |
US20100021561A1 (en) * | 2006-09-21 | 2010-01-28 | Chowhan Masood A | Self-preserved aqueous pharmaceutical compositions |
CN101522171A (zh) * | 2006-09-28 | 2009-09-02 | 爱尔康研究有限公司 | 自身防腐的水性药物组合物 |
WO2008052031A2 (en) * | 2006-10-24 | 2008-05-02 | Alcon Research, Ltd. | 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions |
TWI434926B (zh) * | 2006-12-11 | 2014-04-21 | Alcon Res Ltd | 眼用組成物中聚氧化乙烯-聚氧化丁烯(peo-pbo)嵌段共聚物之使用 |
DK2420223T3 (da) * | 2008-03-17 | 2017-11-06 | Novartis Ag | Vandige farmaceutiske sammensætninger med borat-polyol-komplekser |
TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
US8163684B2 (en) * | 2008-03-26 | 2012-04-24 | Abbott Medical Optics Inc. | Antimicrobials having polyquaternary ammoniums and alcohol-bearing amidoamines and methods for their use |
TWI495469B (zh) | 2008-06-09 | 2015-08-11 | Alcon Res Ltd | 含有氟喹諾酮抗生素藥物之經改良藥學組成物 |
US8093352B2 (en) * | 2008-08-05 | 2012-01-10 | Alcon Research, Ltd. | Polyalkylene oxide polyquaternary ammonium biocides |
TW201023912A (en) | 2008-12-05 | 2010-07-01 | Alcon Res Ltd | Pharmaceutical suspension |
US8431751B1 (en) | 2008-12-24 | 2013-04-30 | Alcon Research, Ltd. | Polymeric quaternary ammonium compounds with vicinal hydroxy groups |
WO2010101989A1 (en) | 2009-03-03 | 2010-09-10 | Alcon Research, Ltd. | PHARMACEUTICAL COMPOSITION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE |
TWI489997B (zh) * | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸-多元醇錯合物之水性藥學組成物 |
TWI547522B (zh) * | 2009-07-07 | 2016-09-01 | 愛爾康研究有限公司 | 環氧乙烷環氧丁烷嵌段共聚物組成物 |
US8999312B2 (en) | 2010-06-02 | 2015-04-07 | Alcon Research, Ltd. | Use of PBO-PEO-PBO block copolymers in ophthalmic compositions |
KR101381903B1 (ko) * | 2011-03-10 | 2014-04-10 | 주식회사 엘지생활건강 | 3-부톡시-1,2-프로판다이올을 함유하는 항균 또는 보존용 조성물 |
JP5989365B2 (ja) * | 2012-03-19 | 2016-09-07 | ロート製薬株式会社 | コンタクトレンズ用眼科組成物 |
WO2017094508A1 (ja) * | 2015-11-30 | 2017-06-08 | ロート製薬株式会社 | 眼科組成物 |
JP2022506555A (ja) | 2018-11-08 | 2022-01-17 | チェン ファン-シン | トリス置換ビグアニド化合物およびその使用 |
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-
1997
- 1997-11-17 EP EP97947519A patent/EP0948357B1/en not_active Expired - Lifetime
- 1997-11-17 CA CA002272308A patent/CA2272308C/en not_active Expired - Lifetime
- 1997-11-17 DE DE69735963T patent/DE69735963T2/de not_active Expired - Lifetime
- 1997-11-17 US US09/308,456 patent/US6319464B1/en not_active Expired - Lifetime
- 1997-11-17 JP JP52667098A patent/JP3724813B2/ja not_active Expired - Lifetime
- 1997-11-17 WO PCT/US1997/020826 patent/WO1998025649A1/en active IP Right Grant
- 1997-11-17 KR KR10-1999-7005231A patent/KR100366676B1/ko not_active IP Right Cessation
- 1997-11-17 AU AU52578/98A patent/AU718199B2/en not_active Expired
- 1997-11-17 ES ES01204124T patent/ES2262603T3/es not_active Expired - Lifetime
- 1997-11-17 AT AT01204124T patent/ATE326983T1/de active
- 1997-11-17 DK DK97947519T patent/DK0948357T3/da active
- 1997-11-17 CN CNB971805768A patent/CN1157227C/zh not_active Expired - Lifetime
- 1997-11-17 DE DE69713388T patent/DE69713388T2/de not_active Expired - Lifetime
- 1997-11-17 NZ NZ336031A patent/NZ336031A/xx not_active IP Right Cessation
- 1997-11-17 PT PT01204124T patent/PT1190718E/pt unknown
- 1997-11-17 AT AT97947519T patent/ATE218887T1/de active
- 1997-11-17 ES ES97947519T patent/ES2178786T3/es not_active Expired - Lifetime
- 1997-11-17 PT PT97947519T patent/PT948357E/pt unknown
-
2000
- 2000-01-18 HK HK00100308A patent/HK1022089A1/xx not_active IP Right Cessation
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2001
- 2001-10-22 US US10/007,423 patent/US6949218B2/en not_active Expired - Lifetime
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2004
- 2004-06-24 JP JP2004186117A patent/JP4276139B2/ja not_active Expired - Lifetime
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2005
- 2005-06-28 US US11/168,788 patent/US7045095B2/en not_active Expired - Lifetime
-
2006
- 2006-01-30 US US11/343,068 patent/US8563011B2/en not_active Expired - Fee Related
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2013
- 2013-09-18 US US14/030,388 patent/US8865776B2/en not_active Expired - Fee Related
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