ES2177961T3 - Procedimiento y dispositivo para la determinacion de un analito en una matriz dispersante. - Google Patents

Procedimiento y dispositivo para la determinacion de un analito en una matriz dispersante.

Info

Publication number
ES2177961T3
ES2177961T3 ES97914097T ES97914097T ES2177961T3 ES 2177961 T3 ES2177961 T3 ES 2177961T3 ES 97914097 T ES97914097 T ES 97914097T ES 97914097 T ES97914097 T ES 97914097T ES 2177961 T3 ES2177961 T3 ES 2177961T3
Authority
ES
Spain
Prior art keywords
light
matrix
depth
pct
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97914097T
Other languages
English (en)
Inventor
Alexander Knuttel
Dirk Boecker
Matthias Essenpreis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2177961T3 publication Critical patent/ES2177961T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA DETERMINAR UN ANALITO CONTENIDO EN UNA MATRIZ DISPERSORA, EN ESPECIAL BIOLOGICA. EN UN PASO DE LA DETERMINACION SE REALIZAN MEDICIONES DE DETECCION, EN LAS CUALES UNA RADIACION LUMINOSA SE DIRIGE A LA MATRIZ (6) COMO LUZ PRIMARIA Y LA RADIACION EMERGENTE DE LA MATRIZ (6) SE DETECTA COMO LUZ SECUNDARIA, CON EL FIN DE DETERMINAR COMO MAGNITUD DE MEDIDA LA PROPIEDAD FISICA MEDIBLE DE LA LUZ QUE VARIA POR LA INTERACCION DE LA LUZ CON LA MATRIZ (6). EN UN PASO DE EVALUACION SE OBTIENE INFORMACION SOBRE LA PRESENCIA DEL ANALITO EN LA MATRIZ (6). LA DETERMINACION DE ANALITOS ABSORBENTES DEBILES DE LA LUZ FRENTE A UN FONDO ABSORBENTE FUERTE PUEDE MEJORARSE SI SE EMPLEAN, COMBINADOS ENTRE SI, DOS PROCEDIMIENTOS DE SELECCION PARA LA RECOGIDA SELECTIVA DE LA LUZ SECUNDARIA. EN EL PRIMERO, LA LUZ PRIMARIA (14) SE ENFOCA MEDIANTE UN ELEMENTO DE ENFOQUE OPTICO (16) SOBRE UN AREA DE FOCO (17) QUE SE ENCUENTRA A UNA PROFUNDIDAD ESPECIFICADA (D) DENTRO DE LA MATRIZ (6) Y EL AREA DE FOCO (17) SE REPRODUCE, MEDIANTE UN ELEMENTO DE ENFOQUE OPTICO (16, 21), EN UNA ABERTURA DE ENTRADA DE LUZ (24) DISPUESTA EN EL CAMINO OPTICO DE LA LUZ SECUNDARIA (19) HACIA EL DETECTOR. EN EL SEGUNDO, UN MEDIO ADICIONAL DE SELECCION DE PROFUNDIDAD, CON PREFERENCIA UN PROCEDIMIENTO DE MEDIDA DE BAJA COHERENCIA, DETECTA COMO LUZ SECUNDARIA LA LUZ REFLEJADA A UNA PROFUNDIDAD DE MEDIDA DEFINIDA, EN QUE LA PROFUNDIDAD DE MEDIDA COINCIDE CON LA PROFUNDIDAD DEL FOCO.
ES97914097T 1996-01-26 1997-01-23 Procedimiento y dispositivo para la determinacion de un analito en una matriz dispersante. Expired - Lifetime ES2177961T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19602656 1996-01-26

Publications (1)

Publication Number Publication Date
ES2177961T3 true ES2177961T3 (es) 2002-12-16

Family

ID=7783677

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97914097T Expired - Lifetime ES2177961T3 (es) 1996-01-26 1997-01-23 Procedimiento y dispositivo para la determinacion de un analito en una matriz dispersante.

Country Status (12)

Country Link
US (1) US5962852A (es)
EP (1) EP0876596B1 (es)
KR (1) KR19990076724A (es)
AT (1) ATE220202T1 (es)
AU (1) AU711422B2 (es)
CA (1) CA2243571A1 (es)
DE (1) DE59707650D1 (es)
ES (1) ES2177961T3 (es)
IL (1) IL125475A0 (es)
NZ (1) NZ330905A (es)
WO (1) WO1997027469A1 (es)
ZA (1) ZA97599B (es)

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JP2004222870A (ja) * 2003-01-21 2004-08-12 Pentax Corp 内視鏡用プローブ
US7307734B2 (en) * 2003-08-14 2007-12-11 University Of Central Florida Interferometric sensor for characterizing materials
US20080082117A1 (en) * 2003-11-12 2008-04-03 Facet Technologies, Llc Lancing device
JP2007510524A (ja) * 2003-11-12 2007-04-26 ファセット・テクノロジーズ・エルエルシー 穿刺装置及びマルチランセットカートリッジ
WO2005058154A1 (en) * 2003-12-16 2005-06-30 Medeikon Corporation Method for monitoring of analytes in biological samples using low coherence interferometry
JP4944770B2 (ja) 2004-04-16 2012-06-06 ファセット・テクノロジーズ・エルエルシー 穿刺装置用のキャップ変位機構及びマルチランセットカートリッジ
US7190464B2 (en) * 2004-05-14 2007-03-13 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
US7474408B2 (en) * 2004-05-14 2009-01-06 Medeikon Corporation Low coherence interferometry utilizing phase
US7327463B2 (en) 2004-05-14 2008-02-05 Medrikon Corporation Low coherence interferometry utilizing magnitude
US20050254059A1 (en) * 2004-05-14 2005-11-17 Alphonse Gerard A Low coherence interferometric system for optical metrology
US7184148B2 (en) 2004-05-14 2007-02-27 Medeikon Corporation Low coherence interferometry utilizing phase
US7242480B2 (en) * 2004-05-14 2007-07-10 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
WO2006004859A2 (en) 2004-06-30 2006-01-12 Facet Technologies, Llc Lancing device and multi-lancet cartridge
WO2006041447A1 (en) * 2004-09-25 2006-04-20 Josh Hogan A compact non-invasive analysis system
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DE102005043573A1 (de) * 2005-04-07 2006-10-12 Universität Duisburg-Essen Vorrichtung und Verfahren zur optischen Untersuchung des menschlichen oder tierischen Körpers
US7488930B2 (en) * 2006-06-02 2009-02-10 Medeikon Corporation Multi-channel low coherence interferometer
EP2101654A4 (en) 2007-01-12 2013-03-06 Facet Technologies Llc MULTILANZETTENKARTUSCHE AND LANZETTENVORRICHTUNG
WO2008152604A1 (en) * 2007-06-15 2008-12-18 Koninklijke Philips Electronics N.V. Spectroscopy measurements
DE102007054309A1 (de) 2007-11-08 2009-05-14 Laser- und Medizin-Technologie GmbH, Berlin (LMTB) Optische Anordnung zur Erhöhung der Wechselwirkungslänge in stark steuernder Matrix
DE102008022372A1 (de) * 2008-05-06 2009-11-12 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Vorrichtung zur Trübungsmessung
US8903476B2 (en) * 2009-03-08 2014-12-02 Oprobe, Llc Multi-function optical probe system for medical and veterinary applications
FR2948801A1 (fr) * 2009-11-24 2011-02-04 Thomson Licensing Procede d'estimation de diffusion de la lumiere
US20110282331A1 (en) 2010-05-13 2011-11-17 Oprobe, Llc Optical coherence tomography with multiple imaging instruments
US10463287B2 (en) 2010-10-06 2019-11-05 Profusa, Inc. Tissue-integrating sensors
US10045722B2 (en) 2013-03-14 2018-08-14 Profusa, Inc. Method and device for correcting optical signals
CN111544011B (zh) * 2013-06-06 2023-06-06 普罗菲尤萨股份有限公司 用于探测来自植入传感器的光信号的设备和方法
US10575766B2 (en) * 2014-03-31 2020-03-03 Sony Corporation Measurement device, measurement method, program, and recording medium
CN106163399B (zh) 2014-03-31 2019-07-12 索尼公司 测量装置、测量方法、程序和记录介质
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Also Published As

Publication number Publication date
EP0876596A1 (de) 1998-11-11
NZ330905A (en) 2000-03-27
AU711422B2 (en) 1999-10-14
DE59707650D1 (de) 2002-08-08
CA2243571A1 (en) 1997-07-31
EP0876596B1 (de) 2002-07-03
KR19990076724A (ko) 1999-10-15
WO1997027469A1 (de) 1997-07-31
IL125475A0 (en) 1999-03-12
AU2150397A (en) 1997-08-20
ATE220202T1 (de) 2002-07-15
ZA97599B (en) 1998-07-24
US5962852A (en) 1999-10-05

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