ES2153807T1 - Secuencias de acido nucleico que pueden ser utilizadas como cebadores y sondas en la amplificacion y deteccion de todos los subtipos de vih-1. - Google Patents
Secuencias de acido nucleico que pueden ser utilizadas como cebadores y sondas en la amplificacion y deteccion de todos los subtipos de vih-1.Info
- Publication number
- ES2153807T1 ES2153807T1 ES98943872T ES98943872T ES2153807T1 ES 2153807 T1 ES2153807 T1 ES 2153807T1 ES 98943872 T ES98943872 T ES 98943872T ES 98943872 T ES98943872 T ES 98943872T ES 2153807 T1 ES2153807 T1 ES 2153807T1
- Authority
- ES
- Spain
- Prior art keywords
- hiv
- sequences
- nucleic acid
- present
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- AIDS & HIV (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Un oligonucleótido sustancialmente complementario a una secuencia de la región LTR de una secuencia de ácido nucleico de un genoma del VIH, teniendo dicho oligonucleótido 10-50 nucleótidos de longitud y comprendiendo al menos un fragmento de 10 nucleótidos de una secuencia seleccionada del grupo que consta de: SEC ID 1: G GGC GCC ACT GCT AGA GA SEC ID 2: G TTC GGG CGC CAC TGC TAGA SEC ID 3: CGGGCGCCACTGCTA SEC ID 4: CTG CTT AAA GCC TCA ATA AA SEC ID 5: CTC AAT AAA GCT TGC CTT GA SEC ID 12: GAT GCA TGC TCA ATA AAG CTT GCC TTG AGT SEC ID 6: TCT GGT AAC TAG AGA TCC CTC SEC ID 7: TAG TGT GTG CCC GTC TGT SEC ID 8: AGT GTG TGC CCG TCT GTT o la secuencia complementaria de las mismas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97202455 | 1997-08-08 | ||
| EP97202455 | 1997-08-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2153807T1 true ES2153807T1 (es) | 2001-03-16 |
| ES2153807T3 ES2153807T3 (es) | 2005-06-16 |
Family
ID=8228630
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10183902T Expired - Lifetime ES2438578T3 (es) | 1997-08-08 | 1998-08-05 | Secuencias de ácidos nucleicos que se pueden usar como cebadores y sondas en la amplificación y detección de todos los subtipos del VIH-1 |
| ES04077617.1T Expired - Lifetime ES2479065T3 (es) | 1997-08-08 | 1998-08-05 | Métodos de uso de secuencias de ácido nucleico como cebadores y sondas en la amplificación y detección de todos los subtipos de VIH-1 |
| ES98943872T Expired - Lifetime ES2153807T3 (es) | 1997-08-08 | 1998-08-05 | Secuencias de acido nucleico que se pueden utilizar como cebadores y sondas en la amplificacion y deteccion de todos los subtipos de vih-1. |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10183902T Expired - Lifetime ES2438578T3 (es) | 1997-08-08 | 1998-08-05 | Secuencias de ácidos nucleicos que se pueden usar como cebadores y sondas en la amplificación y detección de todos los subtipos del VIH-1 |
| ES04077617.1T Expired - Lifetime ES2479065T3 (es) | 1997-08-08 | 1998-08-05 | Métodos de uso de secuencias de ácido nucleico como cebadores y sondas en la amplificación y detección de todos los subtipos de VIH-1 |
Country Status (13)
| Country | Link |
|---|---|
| US (9) | US6881537B1 (es) |
| EP (3) | EP2336367B1 (es) |
| JP (1) | JP3689333B2 (es) |
| KR (1) | KR100615407B1 (es) |
| AT (1) | ATE282720T1 (es) |
| AU (1) | AU736503B2 (es) |
| CA (1) | CA2299275C (es) |
| DE (2) | DE1002138T1 (es) |
| ES (3) | ES2438578T3 (es) |
| GR (1) | GR20010300012T1 (es) |
| ID (1) | ID25877A (es) |
| WO (1) | WO1999007898A1 (es) |
| ZA (1) | ZA987091B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1002138T1 (de) | 1997-08-08 | 2001-06-07 | Akzo Nobel N.V., Arnhem | Nukleinsäuresequenzen als primer und sonden zur amplifizierung und erkennung von allen hiv-1 subtypen |
| DE19836559A1 (de) * | 1998-08-12 | 2000-03-23 | Antigen Gmbh | Gefäß zur Entnahme von Blut |
| DE19850186A1 (de) * | 1998-10-30 | 2000-05-25 | Roche Diagnostics Gmbh | Neue Primer und Sonden zum Nachweis von HIV |
| EP1187939B9 (en) | 1999-07-09 | 2009-08-12 | Gen-Probe Incorporated | Detection of hiv-1 by nucleic acid amplification |
| DE60040874D1 (de) * | 2000-09-01 | 2009-01-02 | Gen Probe Inc | Amplifizierung von hiv-1 sequenzen zur detektion ven einhergehen |
| US6582920B2 (en) | 2000-09-01 | 2003-06-24 | Gen-Probe Incorporated | Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations |
| US20090050492A1 (en) * | 2005-08-02 | 2009-02-26 | Board Of Trustees Of Michigan State University | Nanoporous silicon-based electrochemical nucleic acid biosensor |
| JPWO2007055260A1 (ja) * | 2005-11-11 | 2009-04-30 | 財団法人ヒューマンサイエンス振興財団 | 人免疫不全ウイルス−1遺伝子検出又は定量用材料,検出又は定量方法,治療用遺伝子断片,及び治療方法 |
| US8227590B2 (en) * | 2006-11-21 | 2012-07-24 | Jawaharlal Nehru Centre For Advanced Scientific Research | High sensitivity assay for molecular typing of biological sample, probes and a kit thereof |
| CA2580589C (en) * | 2006-12-19 | 2016-08-09 | Fio Corporation | Microfluidic detection system |
| GB0701253D0 (en) * | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| CA2682826C (en) | 2007-04-02 | 2013-08-13 | Fio Corporation | System and method of deconvolving multiplexed fluorescence spectral signals generated by quantum dot optical coding technology |
| CA2692259C (en) | 2007-06-22 | 2012-07-31 | Fio Corporation | Systems and methods for manufacturing quantum dot-doped polymer microbeads |
| EP2174115B1 (en) * | 2007-07-09 | 2013-08-28 | Fio Corporation | Systems and methods for enhancing fluorescent detection of target molecules in a test sample |
| WO2009012585A1 (en) * | 2007-07-23 | 2009-01-29 | Fio Corporation | A method and system for collating, storing, analyzing and enabling access to collected and analyzed data associated with biological and environmental test subjects |
| CA2702367C (en) * | 2007-10-12 | 2012-08-21 | Fio Corporation | Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto |
| US9873723B2 (en) * | 2008-01-04 | 2018-01-23 | The University Of Melbourne | Diagnostic and therapeutic methods for EFMR (epilepsy and mental retardation limited to females) |
| CA2729023C (en) | 2008-06-25 | 2013-02-26 | Fio Corporation | Bio-threat alert system |
| US9459200B2 (en) | 2008-08-29 | 2016-10-04 | Fio Corporation | Single-use handheld diagnostic test device, and an associated system and method for testing biological and environmental test samples |
| EP2337852A4 (en) * | 2008-09-30 | 2012-03-14 | Univ Northwestern | METHOD AND COMPOSITIONS FOR ISOLATING NUCLEIC ACIDS |
| EP2387721A4 (en) | 2009-01-13 | 2014-05-14 | Fio Corp | PORTABLE DIAGNOSTIC TEST DEVICE AND METHOD FOR USE WITH AN ELECTRONIC DEVICE AND TEST CARTRIDGE FOR QUICK DIAGNOSTIC TESTS |
| KR101007903B1 (ko) * | 2009-05-15 | 2011-01-14 | (주)대영오앤이 | 관절 구조가 개선된 스탠드 장치 |
| JP5461459B2 (ja) * | 2011-03-01 | 2014-04-02 | ジェン−プローブ・インコーポレーテッド | 薬剤耐性突然変異と関連する配列検出のためのhiv−1配列の増幅 |
| JP5461460B2 (ja) * | 2011-03-01 | 2014-04-02 | ジェン−プローブ・インコーポレーテッド | 薬剤耐性突然変異と関連する配列検出のためのhiv−1配列の増幅 |
| JP2012105648A (ja) * | 2011-12-12 | 2012-06-07 | Gen Probe Inc | 薬剤耐性突然変異と関連する配列検出のためのhiv−1配列の増幅 |
| AT513660B1 (de) | 2012-11-30 | 2014-09-15 | Anton Paar Gmbh | Verfahren und Vorrichtung zur Untersuchung von Proben |
| KR101605524B1 (ko) | 2014-02-13 | 2016-03-24 | 대한민국 | Hiv-1 감염인 유래 항레트로바이러스제 내성유전자 염기서열 분석을 위한 프라이머 세트 |
| JP6641305B2 (ja) | 2014-06-26 | 2020-02-05 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 微小管結合タンパク質タウに特異的に結合する抗体及び抗原結合断片 |
| ZA201608812B (en) | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| CN104911277B (zh) * | 2015-04-14 | 2018-02-06 | 广州海力特生物科技有限公司 | 一种检测干血斑标本中人类免疫缺陷病毒1型的试剂盒及其检测方法 |
| CN108998570B (zh) * | 2018-08-14 | 2021-11-02 | 首都医科大学附属北京佑安医院 | 可覆盖多亚型的hiv-1总dna定量检测引物对、探针及检测试剂盒 |
| CN109517806B (zh) * | 2018-12-14 | 2022-05-20 | 中国水产科学研究院珠江水产研究所 | 一种罗非鱼湖病毒强毒株及其rpa检测引物和方法 |
| CN118497421B (zh) * | 2024-05-30 | 2025-02-18 | 中国疾病预防控制中心性病艾滋病预防控制中心 | 基于数字pcr的hiv-1检测方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK171161B1 (da) | 1985-03-28 | 1996-07-08 | Hoffmann La Roche | Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5333675C1 (en) * | 1986-02-25 | 2001-05-01 | Perkin Elmer Corp | Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps |
| US4772547A (en) * | 1986-02-03 | 1988-09-20 | Hoffmann-La Roche Inc. | HTLV-III envelope peptides |
| IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| US5306631A (en) * | 1987-08-21 | 1994-04-26 | University Of Colorado Foundation, Inc. | Compositions and method for inhibition of HIV production |
| US4963532A (en) * | 1987-11-25 | 1990-10-16 | Hem Research, Inc. | dsRNA-based prevention of viral escape |
| EP0331939B1 (en) | 1988-02-16 | 2001-11-14 | Greatbatch Gen-Aid, Ltd | Modified cells having resistance to retroviral infection |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5622820A (en) * | 1988-03-10 | 1997-04-22 | City Of Hope | Method for amplification and detection of RNA and DNA sequences |
| US5221610A (en) * | 1988-05-26 | 1993-06-22 | Institut Pasteur | Diagnostic method and composition for early detection of HIV infection |
| JP3276955B2 (ja) * | 1988-09-30 | 2002-04-22 | ジーン−トラック・システムス | Rnaの鋳型の末端に結合したプローブ構造およびその使用方法 |
| NL8900725A (nl) | 1989-03-23 | 1990-10-16 | Az Univ Amsterdam | Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur. |
| IE64040B1 (en) * | 1989-06-15 | 1995-06-28 | Akzo Nv | Method for determining nucleic acid |
| US5856088A (en) * | 1989-07-11 | 1999-01-05 | Gen-Probe Incorporated | Detection of human immunodeficiency virus type 1 |
| DE69028257T2 (de) | 1989-07-11 | 1997-01-09 | Gen Probe Inc | Verfahren zur Vervielfältigung von Nukleinsäuresequenzen |
| US5122457A (en) * | 1989-10-19 | 1992-06-16 | Schering Corporation | Expression systems utilizing bacteriophage t7 promoters, gene sequences, and t7 rna polymerase |
| WO1991008308A1 (en) | 1989-11-30 | 1991-06-13 | Pharmacia Genetic Engineering, Inc. | A new method for detecting a specific nucleic acid sequence in a sample of cells |
| DE69131596T2 (de) * | 1990-01-10 | 1999-12-23 | Chiron Diagnostics Corp., East Walpole | Dns-abhängige rns-polymerase-transkripte als reportermoleküle zur signalverstärkung in nukleinsäure-hybridisierungsuntersuchungen |
| DE4027616A1 (de) * | 1990-08-31 | 1992-03-05 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung von polymerase-aktivitaet |
| US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| DK173091D0 (da) | 1991-10-11 | 1991-10-11 | Schleroseforeningen The Danish | Biologisk materiale |
| AU681082B2 (en) | 1992-05-06 | 1997-08-21 | Gen-Probe Incorporated | Nucleic acid sequence amplification method, composition and kit |
| US5770428A (en) * | 1993-02-17 | 1998-06-23 | Wisconsin Alumni Research Foundation | Chimeric retrovial expression vectors and particles containing a simple retroviral long terminal repeat, BLV or HIV coding regions and cis-acting regulatory sequences, and an RNA translational enhancer with internal ribsome entry site |
| CA2159103C (en) * | 1993-03-26 | 2002-03-12 | Sherrol H. Mcdonough | Detection of human immunodeficiency virus type 1 |
| US5403707A (en) * | 1993-05-14 | 1995-04-04 | Eastman Kodak Company | Diagnostic compositions, elements, methods and test kits for amplification and detection of retroviral DNA using primers having matched melting temperatures |
| JPH09501562A (ja) * | 1993-07-19 | 1997-02-18 | ジェン−プローブ・インコーポレイテッド | ヒト・免疫不全ウイルスに対する活性を有するオリゴヌクレオチド |
| US6025124A (en) * | 1994-03-03 | 2000-02-15 | The Regents Of The University Of California | Marker, method and an assay for detection and monitoring of latency and activation of human immunodeficiency virus |
| US5576176A (en) | 1994-03-03 | 1996-11-19 | The Regents Of The University Of California | Marker and an assay for detection and monitoring of human immunodeficiency virus latency and activation |
| US5622827A (en) * | 1995-02-07 | 1997-04-22 | Gen-Probe Incorporated | Amplification primers and nucleic acid probes targeted to coccidioides immitis nucleic acid |
| US5599662A (en) | 1995-02-17 | 1997-02-04 | Hoffmann-La Roche Inc. | Oliconucleotide primers and probes for the detection of HIV-1 |
| US5798542A (en) * | 1996-10-08 | 1998-08-25 | Eastman Kodak Company | Image sensor having ITO electrodes with overlapping color filters for increased sensitivity |
| US6001558A (en) | 1997-06-25 | 1999-12-14 | Ortho Clinical Diagnostics, Inc. | Amplification and detection of HIV-1 and/or HIV 2 |
| DE1002138T1 (de) * | 1997-08-08 | 2001-06-07 | Akzo Nobel N.V., Arnhem | Nukleinsäuresequenzen als primer und sonden zur amplifizierung und erkennung von allen hiv-1 subtypen |
| US9004733B2 (en) | 2012-04-05 | 2015-04-14 | Corning Cable Systems Llc | Optical fiber installation tool having a passive illumination feature |
-
1998
- 1998-08-05 DE DE1002138T patent/DE1002138T1/de active Pending
- 1998-08-05 KR KR1020007001327A patent/KR100615407B1/ko not_active Expired - Lifetime
- 1998-08-05 ID ID20000240D patent/ID25877A/id unknown
- 1998-08-05 ES ES10183902T patent/ES2438578T3/es not_active Expired - Lifetime
- 1998-08-05 ES ES04077617.1T patent/ES2479065T3/es not_active Expired - Lifetime
- 1998-08-05 WO PCT/EP1998/004945 patent/WO1999007898A1/en not_active Ceased
- 1998-08-05 ES ES98943872T patent/ES2153807T3/es not_active Expired - Lifetime
- 1998-08-05 EP EP20100183902 patent/EP2336367B1/en not_active Revoked
- 1998-08-05 AU AU91611/98A patent/AU736503B2/en not_active Expired
- 1998-08-05 AT AT98943872T patent/ATE282720T1/de active
- 1998-08-05 EP EP20040077617 patent/EP1568787B1/en not_active Revoked
- 1998-08-05 US US09/463,352 patent/US6881537B1/en not_active Expired - Lifetime
- 1998-08-05 CA CA002299275A patent/CA2299275C/en not_active Expired - Lifetime
- 1998-08-05 JP JP2000506380A patent/JP3689333B2/ja not_active Expired - Lifetime
- 1998-08-05 EP EP98943872A patent/EP1002138B1/en not_active Revoked
- 1998-08-05 DE DE1998604464 patent/DE69804464T2/de not_active Revoked
- 1998-08-06 ZA ZA987091A patent/ZA987091B/xx unknown
-
2001
- 2001-04-30 GR GR20010300012T patent/GR20010300012T1/el unknown
-
2005
- 2005-04-18 US US11/108,233 patent/US8697352B2/en not_active Expired - Fee Related
-
2006
- 2006-03-10 US US11/372,585 patent/US20060228699A1/en not_active Abandoned
- 2006-03-10 US US11/372,577 patent/US20060223056A1/en not_active Abandoned
- 2006-03-10 US US11/372,586 patent/US20060223057A1/en not_active Abandoned
-
2014
- 2014-03-27 US US14/226,965 patent/US9074262B2/en not_active Expired - Fee Related
-
2015
- 2015-06-08 US US14/733,320 patent/US20150292043A1/en not_active Abandoned
-
2016
- 2016-12-14 US US15/378,516 patent/US20170137900A1/en not_active Abandoned
- 2016-12-14 US US15/378,510 patent/US20170145524A1/en not_active Abandoned
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