ES2147663T3 - Bisalcanoilesteres de carnitina que tienen actividad bactericida, fungicida y antiprotozoica. - Google Patents
Bisalcanoilesteres de carnitina que tienen actividad bactericida, fungicida y antiprotozoica.Info
- Publication number
- ES2147663T3 ES2147663T3 ES97830118T ES97830118T ES2147663T3 ES 2147663 T3 ES2147663 T3 ES 2147663T3 ES 97830118 T ES97830118 T ES 97830118T ES 97830118 T ES97830118 T ES 97830118T ES 2147663 T3 ES2147663 T3 ES 2147663T3
- Authority
- ES
- Spain
- Prior art keywords
- carnitine
- fungicide
- bactericide
- bisalcanoilesters
- antiprotozoic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 239000003899 bactericide agent Substances 0.000 title abstract 2
- 230000000855 fungicidal effect Effects 0.000 title abstract 2
- 239000000417 fungicide Substances 0.000 title abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 210000000883 ear external Anatomy 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
ESTERES DE DL -, D - O L - CARNITINA DE FORMULA DONDE: R ES UN GRUPO ALCANOILO SIMPLE O RAMIFICADO, SATURADO O INSATURADO, CON ENTRE 2 Y 16 ATOMOS DE CARBONO; Y ES UNA CADENA ALQUILENA SIMPLE O RAMIFICADA CON ENTRE 3 Y 6 ATOMOS DE CARBONO U ORTO, META O PARAXILILENO; Y X ES EL ANION DE UN ACIDO APTO PARA USO FARMACEUTICO QUE POSEE UNA POTENTE ACCION BACTERICIDA, FUNGICIDA O ANTIPROTOZOICA. SE DESCRIBEN LOS PROCESOS PARA SU PREPARACION Y COMPOSICIONES DE APLICACION TOPICA PARA EL TRATAMIENTO DE INFECCIONES DE LA PIEL, EL OIDO EXTERNO Y LAS MUCOSAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000180A IT1283955B1 (it) | 1996-03-20 | 1996-03-20 | Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2147663T3 true ES2147663T3 (es) | 2000-09-16 |
Family
ID=11404010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97830118T Expired - Lifetime ES2147663T3 (es) | 1996-03-20 | 1997-03-14 | Bisalcanoilesteres de carnitina que tienen actividad bactericida, fungicida y antiprotozoica. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5925369A (es) |
EP (1) | EP0796841B1 (es) |
JP (1) | JP4077052B2 (es) |
KR (1) | KR100491099B1 (es) |
AT (1) | ATE193521T1 (es) |
CA (1) | CA2200409C (es) |
DE (1) | DE69702158T2 (es) |
DK (1) | DK0796841T3 (es) |
ES (1) | ES2147663T3 (es) |
GR (1) | GR3034243T3 (es) |
IT (1) | IT1283955B1 (es) |
PT (1) | PT796841E (es) |
TW (1) | TW491828B (es) |
ZA (1) | ZA972374B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1306129B1 (it) * | 1999-04-13 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti |
EA017935B1 (ru) | 2006-05-19 | 2013-04-30 | Мэри Кэй Инк. | Композиция для ухода за кожей и ее применение |
KR102158895B1 (ko) | 2013-03-12 | 2020-09-22 | 마리 케이 인코포레이티드 | 보존 시스템 |
CN105017045B (zh) * | 2015-06-09 | 2017-11-07 | 中北大学 | 一种连接基含双酯基的双季铵盐及其作为杀菌剂的应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2497673A (en) * | 1946-04-16 | 1950-02-14 | Du Pont | Reaction of alpha-beta unsaturated compounds with aromatic hydrocarbons and products obtained |
US2712025A (en) * | 1951-09-26 | 1955-06-28 | Chessie E Rehberg | Production of dicarboxylic acid esters of alpha-hydroxycarboxylic acid esters |
IT1201481B (it) * | 1985-10-08 | 1989-02-02 | Prodotti Antibiotici Spa | Pantotenil derivati |
IT1254135B (it) * | 1992-01-16 | 1995-09-08 | Sigma Tau Ind Farmaceuti | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica. |
IT1254136B (it) * | 1992-01-16 | 1995-09-08 | Sigma Tau Ind Farmaceuti | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica. |
AU4534593A (en) * | 1992-06-12 | 1994-01-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
-
1996
- 1996-03-20 IT IT96RM000180A patent/IT1283955B1/it active IP Right Grant
-
1997
- 1997-03-10 TW TW086103027A patent/TW491828B/zh not_active IP Right Cessation
- 1997-03-14 ES ES97830118T patent/ES2147663T3/es not_active Expired - Lifetime
- 1997-03-14 EP EP97830118A patent/EP0796841B1/en not_active Expired - Lifetime
- 1997-03-14 DK DK97830118T patent/DK0796841T3/da active
- 1997-03-14 DE DE69702158T patent/DE69702158T2/de not_active Expired - Lifetime
- 1997-03-14 US US08/818,737 patent/US5925369A/en not_active Expired - Fee Related
- 1997-03-14 PT PT97830118T patent/PT796841E/pt unknown
- 1997-03-14 AT AT97830118T patent/ATE193521T1/de not_active IP Right Cessation
- 1997-03-19 CA CA002200409A patent/CA2200409C/en not_active Expired - Fee Related
- 1997-03-19 ZA ZA9702374A patent/ZA972374B/xx unknown
- 1997-03-20 KR KR1019970009443A patent/KR100491099B1/ko not_active IP Right Cessation
- 1997-03-21 JP JP06784297A patent/JP4077052B2/ja not_active Expired - Fee Related
-
2000
- 2000-08-23 GR GR20000401930T patent/GR3034243T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH107631A (ja) | 1998-01-13 |
KR970065506A (ko) | 1997-10-13 |
JP4077052B2 (ja) | 2008-04-16 |
TW491828B (en) | 2002-06-21 |
IT1283955B1 (it) | 1998-05-07 |
ZA972374B (en) | 1997-10-20 |
GR3034243T3 (en) | 2000-12-29 |
ATE193521T1 (de) | 2000-06-15 |
US5925369A (en) | 1999-07-20 |
DK0796841T3 (da) | 2000-11-13 |
DE69702158T2 (de) | 2000-10-19 |
MX9702043A (es) | 1998-03-31 |
CA2200409A1 (en) | 1997-09-20 |
ITRM960180A0 (es) | 1996-03-20 |
DE69702158D1 (de) | 2000-07-06 |
ITRM960180A1 (it) | 1997-09-20 |
PT796841E (pt) | 2000-09-29 |
KR100491099B1 (ko) | 2006-01-12 |
EP0796841A1 (en) | 1997-09-24 |
CA2200409C (en) | 2006-11-28 |
EP0796841B1 (en) | 2000-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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