ES2139824T3 - Uso de 1,4-dihidropiridinas con puente 1,2 como moduladores selectivos de canales de potasio. - Google Patents
Uso de 1,4-dihidropiridinas con puente 1,2 como moduladores selectivos de canales de potasio.Info
- Publication number
- ES2139824T3 ES2139824T3 ES95119052T ES95119052T ES2139824T3 ES 2139824 T3 ES2139824 T3 ES 2139824T3 ES 95119052 T ES95119052 T ES 95119052T ES 95119052 T ES95119052 T ES 95119052T ES 2139824 T3 ES2139824 T3 ES 2139824T3
- Authority
- ES
- Spain
- Prior art keywords
- dihydropyridines
- bridge
- potassium channel
- channel modulators
- selective potassium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Manufacture Of Tobacco Products (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA PRESENTE INVENCION TRATA FE LA NUEVA UTILIZACION DE LAS CONOCIDAS EN PARTE 1,4-DIHIDROPIRIDINAS 1,2-PUENTEADAS DE FORMULA GENERAL (I), DONDE R{SUP,1} A R{SUP,4} Y A TIENEN EL SIGNIFICADO DADO EN LA DESCRIPCION, EL PROCEDIMIENTO PARA SU OBTENCION Y SU USO COMO MEDICAMENTOS, DADO QUE SON MODULADORES SELECTIVOS DEL CANAL DE POTASIO, EN EL TRATAMIENTO DEL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4444860A DE4444860A1 (de) | 1994-12-16 | 1994-12-16 | Verwendung von 1,2-überbrückten 1,4-Dihydropyridinen als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2139824T3 true ES2139824T3 (es) | 2000-02-16 |
Family
ID=6535985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95119052T Expired - Lifetime ES2139824T3 (es) | 1994-12-16 | 1995-12-04 | Uso de 1,4-dihidropiridinas con puente 1,2 como moduladores selectivos de canales de potasio. |
Country Status (25)
Country | Link |
---|---|
US (2) | US5990121A (es) |
EP (2) | EP0924211A3 (es) |
JP (1) | JPH08239384A (es) |
KR (1) | KR960022517A (es) |
CN (1) | CN1059442C (es) |
AT (1) | ATE186536T1 (es) |
AU (1) | AU709760B2 (es) |
CA (1) | CA2165131A1 (es) |
CZ (1) | CZ332895A3 (es) |
DE (2) | DE4444860A1 (es) |
DK (1) | DK0717043T3 (es) |
EE (1) | EE9500076A (es) |
ES (1) | ES2139824T3 (es) |
FI (1) | FI956016A (es) |
GR (1) | GR3032394T3 (es) |
HU (1) | HUT74166A (es) |
IL (1) | IL116386A (es) |
MX (1) | MX9505097A (es) |
NO (1) | NO955103L (es) |
NZ (1) | NZ280661A (es) |
PL (1) | PL180439B1 (es) |
RU (1) | RU2155765C2 (es) |
SI (1) | SI0717043T1 (es) |
SK (1) | SK158095A3 (es) |
ZA (1) | ZA9510695B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050075359A1 (en) * | 2003-03-14 | 2005-04-07 | Rikako Kono | Large conductance calcium-activated K channel opener |
US7394475B2 (en) * | 2004-02-13 | 2008-07-01 | Infoprint Solutions Company, Llc | Apparatus, system, and method for image registration |
EP1782812A1 (en) * | 2004-06-23 | 2007-05-09 | Neurotec Pharma, S.L. | Compounds for the treatment of inflammation of the central nervous system |
EP1782815B1 (en) * | 2004-06-23 | 2010-09-08 | Neurotec Pharma, S.L. | Compound for use in the diagnosis of cns acute damage |
WO2006074419A2 (en) * | 2005-01-07 | 2006-07-13 | Roskamp Research Llc | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE220633C (es) * | ||||
US4053614A (en) * | 1972-03-06 | 1977-10-11 | Bayer Aktiengesellschaft | 1,2-pentamethylene-1,4-dihydropyridine derivatives |
US3951988A (en) * | 1972-03-06 | 1976-04-20 | Bayer Aktiengesellschaft | 1,2-Pentamethylene-1,4-dihydropyridine derivatives |
US3935220A (en) * | 1972-03-06 | 1976-01-27 | Bayer Aktiengesellschaft | Tetrahydroimidazolo[1,2-a]pyridine derivatives |
DE2210674C3 (de) * | 1972-03-06 | 1981-09-24 | Bayer Ag, 5090 Leverkusen | 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
DE2210633C2 (de) * | 1972-03-06 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Kondensierte Pyridinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
US5225566A (en) * | 1992-05-08 | 1993-07-06 | American Home Products Corporation | Indazolanonyl derivative of benzopyran |
-
1994
- 1994-12-16 DE DE4444860A patent/DE4444860A1/de not_active Withdrawn
-
1995
- 1995-12-04 EP EP99105350A patent/EP0924211A3/de not_active Withdrawn
- 1995-12-04 SI SI9530352T patent/SI0717043T1/xx unknown
- 1995-12-04 DE DE59507220T patent/DE59507220D1/de not_active Expired - Fee Related
- 1995-12-04 ES ES95119052T patent/ES2139824T3/es not_active Expired - Lifetime
- 1995-12-04 DK DK95119052T patent/DK0717043T3/da active
- 1995-12-04 EP EP95119052A patent/EP0717043B1/de not_active Expired - Lifetime
- 1995-12-04 AT AT95119052T patent/ATE186536T1/de not_active IP Right Cessation
- 1995-12-06 MX MX9505097A patent/MX9505097A/es unknown
- 1995-12-07 AU AU40294/95A patent/AU709760B2/en not_active Ceased
- 1995-12-08 US US08/569,534 patent/US5990121A/en not_active Expired - Fee Related
- 1995-12-13 JP JP7346244A patent/JPH08239384A/ja active Pending
- 1995-12-13 CA CA002165131A patent/CA2165131A1/en not_active Abandoned
- 1995-12-13 NZ NZ280661A patent/NZ280661A/en unknown
- 1995-12-14 FI FI956016A patent/FI956016A/fi unknown
- 1995-12-14 IL IL11638695A patent/IL116386A/xx not_active IP Right Cessation
- 1995-12-14 PL PL95311843A patent/PL180439B1/pl unknown
- 1995-12-15 EE EE9500076A patent/EE9500076A/xx unknown
- 1995-12-15 ZA ZA9510695A patent/ZA9510695B/xx unknown
- 1995-12-15 KR KR1019950050396A patent/KR960022517A/ko not_active Application Discontinuation
- 1995-12-15 HU HU9503597A patent/HUT74166A/hu unknown
- 1995-12-15 NO NO955103A patent/NO955103L/no not_active Application Discontinuation
- 1995-12-15 CZ CZ953328A patent/CZ332895A3/cs unknown
- 1995-12-15 RU RU95121078/04A patent/RU2155765C2/ru active
- 1995-12-15 SK SK1580-95A patent/SK158095A3/sk unknown
- 1995-12-15 CN CN95120851A patent/CN1059442C/zh not_active Expired - Fee Related
-
1999
- 1999-07-28 US US09/362,409 patent/US6147087A/en not_active Expired - Fee Related
-
2000
- 2000-01-14 GR GR20000400088T patent/GR3032394T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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