ES2132046T3 - Sintasas isoprenoides quimericas y usos de las mismas. - Google Patents

Sintasas isoprenoides quimericas y usos de las mismas.

Info

Publication number
ES2132046T3
ES2132046T3 ES97921142T ES97921142T ES2132046T3 ES 2132046 T3 ES2132046 T3 ES 2132046T3 ES 97921142 T ES97921142 T ES 97921142T ES 97921142 T ES97921142 T ES 97921142T ES 2132046 T3 ES2132046 T3 ES 2132046T3
Authority
ES
Spain
Prior art keywords
isoprenoid
polypeptide
domain
chemeric
synthease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97921142T
Other languages
English (en)
Spanish (es)
Other versions
ES2132046T1 (es
Inventor
Joseph Chappell
Kyoungwhan Back
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Kentucky
Original Assignee
University of Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Kentucky filed Critical University of Kentucky
Publication of ES2132046T1 publication Critical patent/ES2132046T1/es
Application granted granted Critical
Publication of ES2132046T3 publication Critical patent/ES2132046T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
ES97921142T 1996-04-12 1997-04-11 Sintasas isoprenoides quimericas y usos de las mismas. Expired - Lifetime ES2132046T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/631,341 US5824774A (en) 1996-04-12 1996-04-12 Chimeric isoprenoid synthases and uses thereof

Publications (2)

Publication Number Publication Date
ES2132046T1 ES2132046T1 (es) 1999-08-16
ES2132046T3 true ES2132046T3 (es) 2003-03-16

Family

ID=24530791

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97921142T Expired - Lifetime ES2132046T3 (es) 1996-04-12 1997-04-11 Sintasas isoprenoides quimericas y usos de las mismas.

Country Status (25)

Country Link
US (2) US5824774A (en:Method)
EP (2) EP1229122A3 (en:Method)
JP (4) JP2000508899A (en:Method)
KR (1) KR20000005385A (en:Method)
AP (1) AP808A (en:Method)
AR (1) AR006638A1 (en:Method)
AT (1) ATE223225T1 (en:Method)
AU (1) AU2726497A (en:Method)
BR (1) BR9708650A (en:Method)
CA (1) CA2250712C (en:Method)
CZ (1) CZ294613B6 (en:Method)
DE (2) DE904095T1 (en:Method)
EA (1) EA001622B1 (en:Method)
ES (1) ES2132046T3 (en:Method)
GR (1) GR990300025T1 (en:Method)
ID (1) ID19769A (en:Method)
IL (2) IL126486A0 (en:Method)
IN (1) IN186316B (en:Method)
OA (1) OA10895A (en:Method)
PL (1) PL329404A1 (en:Method)
PT (1) PT904095E (en:Method)
TR (1) TR199802043T2 (en:Method)
TW (1) TW509724B (en:Method)
WO (1) WO1997038703A1 (en:Method)
ZA (1) ZA973108B (en:Method)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8106260B2 (en) * 1996-04-12 2012-01-31 The Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US7186891B1 (en) * 1996-04-12 2007-03-06 University Of Kentucky, Research Foundation Plant cells and plants expressing chimeric isoprenoid synthases
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US5945726A (en) * 1996-12-16 1999-08-31 Micron Technology, Inc. Lateral bipolar transistor
AR022383A1 (es) 1998-09-18 2002-09-04 Univ Kentucky Res Found Sintasas
US20040005673A1 (en) * 2001-06-29 2004-01-08 Kevin Jarrell System for manipulating nucleic acids
ATE439437T1 (de) * 1999-01-05 2009-08-15 Univ Boston Verbessertes klonierungsverfahren
US6358712B1 (en) 1999-01-05 2002-03-19 Trustee Of Boston University Ordered gene assembly
EP2281890A1 (en) 2000-07-31 2011-02-09 Danisco US Inc. Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
AU2013204829B2 (en) * 2001-03-09 2013-07-04 University Of Kentucky Research Foundation Cytochrome P450s and uses thereof
CA2954889A1 (en) 2001-03-09 2002-09-19 University Of Kentucky Research Foundation Cytochrome p450s and uses thereof
AU2012202780B2 (en) * 2001-03-09 2014-07-03 University Of Kentucky Research Foundation Cytochrome P450s and Uses Thereof
US7172886B2 (en) * 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
US7192751B2 (en) * 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
US8124811B2 (en) 2007-03-20 2012-02-28 Allylix, Inc. Fragrance and methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one
US8268553B2 (en) 2007-06-01 2012-09-18 Sapphire Energy, Inc. High throughput screening of genetically modified photosynthetic organisms
NZ583701A (en) * 2007-09-11 2012-03-30 Sapphire Energy Inc Molecule production by photosynthetic organisms
CL2008002680A1 (es) 2007-09-11 2009-10-16 Sapphire Energy Inc Composicion que comprende moleculas con atomos de hidrogeno y carbono que representan a lo menos 80% del peso de la composicion, y donde la distribucion de carbono 13 de la composicion es inferior a -32 0/00; producto combustible que comprende la composicion, y metodo para la generacion de dioxido de carbono.
SG162265A1 (en) * 2007-12-13 2010-07-29 Danisco Us Inc Compositions and methods for producing isoprene
US8034992B2 (en) * 2008-06-16 2011-10-11 Academia Sinica Gibberellin 2-oxidase genes and uses thereof
EP2326707B1 (en) 2008-08-12 2016-11-23 Evolva, Inc. Method for production of isoprenoids
AU2011320127B2 (en) 2010-10-29 2015-10-01 Evolva, Inc. Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
WO2013110191A1 (en) 2012-01-23 2013-08-01 The University Of British Columbia Abc trepenoid transporters and methods of using the same
JP5950253B2 (ja) * 2012-02-13 2016-07-13 住友ゴム工業株式会社 イソプレノイドの製造方法、及びイソプレノイド
US9353385B2 (en) 2012-07-30 2016-05-31 Evolva, Inc. Sclareol and labdenediol diphosphate synthase polypeptides, encoding nucleic acid molecules and uses thereof
US9885023B2 (en) 2012-11-01 2018-02-06 University Of British Columbia Cytochrome P450 and cytochrome P450 reductase polypeptides, encoding nucleic acid molecules and uses thereof
WO2014150599A1 (en) 2013-03-14 2014-09-25 Allylix, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
CN111621508B (zh) * 2020-06-11 2022-07-01 云南中烟工业有限责任公司 烟草萜类合成酶NtTPS7基因及其载体与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2159735A1 (en) * 1993-04-02 1994-10-13 Terry Euclaire Meyer Southern corn rootworm control with limonene
CA2118071C (en) * 1993-10-28 2004-09-14 Rodney B. Croteau Dna encoding limonene synthase from mentha spicata
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof

Also Published As

Publication number Publication date
JP2012005499A (ja) 2012-01-12
ZA973108B (en) 1997-11-04
AU2726497A (en) 1997-11-07
CA2250712C (en) 2008-07-08
OA10895A (en) 2001-10-11
EP1229122A3 (en) 2002-10-09
DE69715192D1 (de) 2002-10-10
PL329404A1 (en) 1999-03-29
IL126486A (en) 2006-04-10
EA199800917A1 (ru) 1999-04-29
AP9700971A0 (en) 1997-07-31
US5824774A (en) 1998-10-20
DE69715192T2 (de) 2003-04-30
EP1229122A2 (en) 2002-08-07
ID19769A (id) 1998-07-30
US6072045A (en) 2000-06-06
EP0904095A4 (en) 1999-07-07
EA001622B1 (ru) 2001-06-25
KR20000005385A (ko) 2000-01-25
AR006638A1 (es) 1999-09-08
AP808A (en) 2000-02-29
TR199802043T2 (xx) 1999-01-18
TW509724B (en) 2002-11-11
ATE223225T1 (de) 2002-09-15
JP2015171387A (ja) 2015-10-01
BR9708650A (pt) 1999-08-03
HK1017275A1 (en) 1999-11-19
GR990300025T1 (en) 1999-07-30
CZ294613B6 (cs) 2005-02-16
EP0904095B1 (en) 2002-09-04
DE904095T1 (de) 1999-10-07
JP2000508899A (ja) 2000-07-18
IN186316B (en:Method) 2001-08-04
WO1997038703A1 (en) 1997-10-23
CZ317998A3 (cs) 1999-02-17
EP0904095A1 (en) 1999-03-31
JP2015057074A (ja) 2015-03-26
ES2132046T1 (es) 1999-08-16
IL126486A0 (en) 1999-08-17
CA2250712A1 (en) 1997-10-23
PT904095E (pt) 2002-12-31

Similar Documents

Publication Publication Date Title
ES2132046T3 (es) Sintasas isoprenoides quimericas y usos de las mismas.
ES2105999T3 (es) Procedimiento para la preparacion industrial de fosfatidilserina.
DK0828717T3 (da) Fremgangsmåde til fremstilling af 3-haloalkyl-1H-pyrazol
ES2191702T3 (es) Fv monocatenarios anti-egfr y anticuerpos anti-egfr.
MX9701419A (es) Reduccion de hibridizacion no especifica mediante la utilizacion de esquemas novedosos de pareamiento de bases.
DE3854757D1 (de) Verfahren zur elektrokatalytischen Umsetzung von leichten Kohlenwasserstoffen in Synthesegas.
ES2114514T1 (es) Conjunto de rodillo para fresar carreteras y metodo de fresado.
ES2185705T3 (es) Proteina bifuncional, preparacion y uso.
DE69719057D1 (de) Verfahren zur signalverstärkung
TR199902426T2 (xx) Bitki b�ceklerinin kontrol�.
DK1032705T3 (da) Probearrays og fremgangsmåder til at benytte probearrays til at skelne mellem DNA
DE69607830D1 (de) Verfahren zur isothermer amplifikation von nukleinsäure molekülen
ATE397099T1 (de) Oligonukleotidprimer zur reversen transkription für den effizienten nachweis von hiv-1 und hiv-2 und methoden ihrer verwendung
ES2169025T3 (es) Compuestos, vectores y procedimiento para expresar fosfolipasa a2 citosolica humana.
ATE403864T1 (de) Verfahren zur identifizierung von substanzen, die die aktivität von hyperpolarisations-aktivierten kationen-kanälen modulieren
ATE414795T1 (de) Antikörperbibliotheken
EA200200974A1 (ru) Моноклональные антитела к рецептору лпнп человека, их получение и применение
ES2119001T3 (es) Determinacion de un analito en una muestra liquida.
ES2171913T3 (es) Procedimiento de puesta en evidencia de contaminantes microbiologicos vivos en una muestra de producto de uso alimentario.
EA199700196A1 (ru) Способ получения фактора ix из биологических источников и фактор ix, полученный этим способом
ES2135143T3 (es) Procedimiento para la fabricacion de pentenales.
SE0004334D0 (sv) Electron spectroscopy
CY1105675T1 (el) Πρωτεϊνη ροσδενουσα αγγειοστατινη
ES2133820T3 (es) Marcador para patologias que implican una reaccion autoinmune y/o para enfermedades inflamatorias.
DE50208262D1 (de) Verfahren zur bestimmung von flüchtigen substanzen in lösung