ES2122991T3 - Derivado de tiazolidina-2,4, sal de dicho derivado y su produccion. - Google Patents
Derivado de tiazolidina-2,4, sal de dicho derivado y su produccion.Info
- Publication number
- ES2122991T3 ES2122991T3 ES92905305T ES92905305T ES2122991T3 ES 2122991 T3 ES2122991 T3 ES 2122991T3 ES 92905305 T ES92905305 T ES 92905305T ES 92905305 T ES92905305 T ES 92905305T ES 2122991 T3 ES2122991 T3 ES 2122991T3
- Authority
- ES
- Spain
- Prior art keywords
- derivative
- same
- salt
- thiazolidine
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
Abstract
UN DERIVADO NUEVO DE LA TIAZOLIDINA IVIDADES HIPOGLICEMICA E INHIBITORIA DE REDUCTASA DE ALDOSA, REPRESENTADA POR LA FORMULA GENERAL (1) O (2), UNA SAL DEL MISMO, UN PROCESO PARA PRODUCIRLO Y UNA MEDICINA QUE LO CONTIENE, EN DONDE R1 Y R2 PUEDEN SER LO MISMO O DISTINTOS ENTRE SI Y CADA UNO REPRESENTA HIDROGENO O ALQUILO INFERIOR; R3 REPRESENTA FENIL NAFTILO, BENZOILO, HETEROCILCO DE 5ANILLO CONDENSADO QUE CONTIENE BENCENO DEL MISMO, TODOS ELLOS PUEDEN TENER, AL MENOS, UN SUBSTITUYENTE; A REPRESENTA CARBONILO, SULFONILO O UN ENLACE LIBRE; Y B REPRESENTA ALQUILENO INFERIOR, ALQUENILENO INFERIOR O UN ENLACE LIBRE, EN LA FORMULA (2) R4 REPRESENTA HIDROGENO O UN ALQUILO INFERIOR Y R1 Y R3 SON LO DEFINIDO ANTERIORMENTE.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5327591 | 1991-02-25 | ||
JP4072496A JP3053490B2 (ja) | 1991-02-25 | 1992-02-21 | チアゾリジン−2,4−ジオン誘導体とその塩及び製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2122991T3 true ES2122991T3 (es) | 1999-01-01 |
Family
ID=26393992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92905305T Expired - Lifetime ES2122991T3 (es) | 1991-02-25 | 1992-02-24 | Derivado de tiazolidina-2,4, sal de dicho derivado y su produccion. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5342850A (es) |
EP (1) | EP0526658B1 (es) |
JP (1) | JP3053490B2 (es) |
KR (1) | KR960012206B1 (es) |
AT (1) | ATE171448T1 (es) |
AU (1) | AU645886B2 (es) |
CA (1) | CA2081113C (es) |
DE (1) | DE69227080T2 (es) |
DK (1) | DK0526658T3 (es) |
ES (1) | ES2122991T3 (es) |
HU (1) | HU217116B (es) |
WO (1) | WO1992014719A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL113084A (en) * | 1994-03-23 | 1999-01-26 | Sankyo Co | Derivatives of thiazolidine and oxazolidine, processes for their preparation and pharmaceutical preparations containing them |
FR2733685B1 (fr) * | 1995-05-05 | 1997-05-30 | Adir | Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant |
JP3906935B2 (ja) * | 1995-12-18 | 2007-04-18 | 杏林製薬株式会社 | N−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
JP3373198B2 (ja) * | 1997-12-19 | 2003-02-04 | メルク エンド カムパニー インコーポレーテッド | アリールチアゾリジンジオン誘導体 |
US6008237A (en) * | 1997-12-19 | 1999-12-28 | Merck & Co., Inc. | Arylthiazolidinedione derivatives |
US6756360B1 (en) * | 1998-12-24 | 2004-06-29 | Metabasis Therapeutics, Inc. | Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes |
AU770870B2 (en) | 1999-06-18 | 2004-03-04 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
JP2003502369A (ja) * | 1999-06-18 | 2003-01-21 | メルク エンド カムパニー インコーポレーテッド | アリールチアゾリジンジオン誘導体およびアリールオキサゾリジンジオン誘導体 |
SK8892002A3 (en) * | 1999-12-22 | 2003-04-01 | Metabasis Therapeutics Inc | Novel bisamidate phosphonate prodrugs, process for their preparation and use thereof |
AU2001228854A1 (en) * | 2000-02-01 | 2001-08-14 | Kyorin Pharmaceutical Co. Ltd. | Alkali metal salt of thiazolidine-2,4-dione derivative |
CA2407349A1 (en) | 2000-04-25 | 2002-10-24 | Kyorin Pharmaceutical Co., Ltd. | Novel stable crystal of thiazolidinedione derivative and process for producing the same |
US7563774B2 (en) * | 2000-06-29 | 2009-07-21 | Metabasis Therapeutics, Inc. | Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes |
ITRM20020016A1 (it) * | 2002-01-15 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza |
US20070225259A1 (en) * | 2004-08-18 | 2007-09-27 | Qun Dang | Novel Thiazole Inhibitors of Fructose 1,6-Bishosphatase |
US8686048B2 (en) * | 2010-05-06 | 2014-04-01 | Rhizen Pharmaceuticals Sa | Immunomodulator and anti-inflammatory compounds |
KR102384153B1 (ko) | 2018-01-09 | 2022-04-06 | 주식회사 엘지에너지솔루션 | 이형지 커버를 포함하는 전지팩 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
JPS5728073A (en) * | 1980-07-29 | 1982-02-15 | Takeda Chem Ind Ltd | Inhibitor for aldose reducing enzyme |
DE3479419D1 (en) * | 1983-01-17 | 1989-09-21 | Pfizer | Aldose reductase inhibiting 5-(2-alkoxyphenyl)thiazolidinediones |
DE10199003I1 (de) * | 1987-09-04 | 2003-06-12 | Beecham Group Plc | Substituierte Thiazolidinionderivate |
-
1992
- 1992-02-21 JP JP4072496A patent/JP3053490B2/ja not_active Expired - Fee Related
- 1992-02-24 CA CA002081113A patent/CA2081113C/en not_active Expired - Fee Related
- 1992-02-24 AU AU12059/92A patent/AU645886B2/en not_active Ceased
- 1992-02-24 WO PCT/JP1992/000189 patent/WO1992014719A1/ja active IP Right Grant
- 1992-02-24 KR KR1019920702622A patent/KR960012206B1/ko not_active IP Right Cessation
- 1992-02-24 EP EP92905305A patent/EP0526658B1/en not_active Expired - Lifetime
- 1992-02-24 AT AT92905305T patent/ATE171448T1/de not_active IP Right Cessation
- 1992-02-24 US US07/934,519 patent/US5342850A/en not_active Expired - Fee Related
- 1992-02-24 DK DK92905305T patent/DK0526658T3/da active
- 1992-02-24 HU HU9203284A patent/HU217116B/hu not_active IP Right Cessation
- 1992-02-24 DE DE69227080T patent/DE69227080T2/de not_active Expired - Fee Related
- 1992-02-24 ES ES92905305T patent/ES2122991T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0526658B1 (en) | 1998-09-23 |
KR960012206B1 (ko) | 1996-09-16 |
EP0526658A1 (en) | 1993-02-10 |
WO1992014719A1 (en) | 1992-09-03 |
KR937000469A (ko) | 1993-03-15 |
EP0526658A4 (en) | 1993-04-21 |
HU217116B (hu) | 1999-11-29 |
ATE171448T1 (de) | 1998-10-15 |
DE69227080T2 (de) | 1999-05-20 |
AU645886B2 (en) | 1994-01-27 |
HU9203284D0 (en) | 1992-12-28 |
US5342850A (en) | 1994-08-30 |
DE69227080D1 (de) | 1998-10-29 |
HUT66972A (en) | 1995-01-30 |
CA2081113A1 (en) | 1992-08-26 |
JPH0592960A (ja) | 1993-04-16 |
JP3053490B2 (ja) | 2000-06-19 |
CA2081113C (en) | 2001-03-06 |
DK0526658T3 (da) | 1999-06-14 |
AU1205992A (en) | 1992-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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