ATE171448T1 - Thiazolidin-2,4-dione, salze hiervon sowie verfahren zur herstellung - Google Patents

Thiazolidin-2,4-dione, salze hiervon sowie verfahren zur herstellung

Info

Publication number
ATE171448T1
ATE171448T1 AT92905305T AT92905305T ATE171448T1 AT E171448 T1 ATE171448 T1 AT E171448T1 AT 92905305 T AT92905305 T AT 92905305T AT 92905305 T AT92905305 T AT 92905305T AT E171448 T1 ATE171448 T1 AT E171448T1
Authority
AT
Austria
Prior art keywords
same
thiazolidine
dione
lower alkyl
salts
Prior art date
Application number
AT92905305T
Other languages
English (en)
Inventor
Michiro Tomonuma Nogi-M Ohnota
Kyuya - Nisshincho -Ch Okamura
Yoshihiro - Bessho-Mach Hirata
Koji Tomonuma Murakami
Mitsuo - Suna Ohashi
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Application granted granted Critical
Publication of ATE171448T1 publication Critical patent/ATE171448T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT92905305T 1991-02-25 1992-02-24 Thiazolidin-2,4-dione, salze hiervon sowie verfahren zur herstellung ATE171448T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5327591 1991-02-25
JP4072496A JP3053490B2 (ja) 1991-02-25 1992-02-21 チアゾリジン−２，４−ジオン誘導体とその塩及び製造法

Publications (1)

Publication Number Publication Date
ATE171448T1 true ATE171448T1 (de) 1998-10-15

Family

ID=26393992

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92905305T ATE171448T1 (de) 1991-02-25 1992-02-24 Thiazolidin-2,4-dione, salze hiervon sowie verfahren zur herstellung

Country Status (12)

Country Link
US (1) US5342850A (de)
EP (1) EP0526658B1 (de)
JP (1) JP3053490B2 (de)
KR (1) KR960012206B1 (de)
AT (1) ATE171448T1 (de)
AU (1) AU645886B2 (de)
CA (1) CA2081113C (de)
DE (1) DE69227080T2 (de)
DK (1) DK0526658T3 (de)
ES (1) ES2122991T3 (de)
HU (1) HU217116B (de)
WO (1) WO1992014719A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL113084A (en) * 1994-03-23 1999-01-26 Sankyo Co Derivatives of thiazolidine and oxazolidine, processes for their preparation and pharmaceutical preparations containing them
FR2733685B1 (fr) * 1995-05-05 1997-05-30 Adir Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant
JP3906935B2 (ja) * 1995-12-18 2007-04-18 杏林製薬株式会社 Ｎ−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法
US6008237A (en) 1997-12-19 1999-12-28 Merck & Co., Inc. Arylthiazolidinedione derivatives
JP3373198B2 (ja) * 1997-12-19 2003-02-04 メルク エンド カムパニー インコーポレーテッド アリールチアゾリジンジオン誘導体
US6756360B1 (en) * 1998-12-24 2004-06-29 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes
WO2000078312A1 (en) * 1999-06-18 2000-12-28 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
EP1194147B1 (de) 1999-06-18 2007-01-10 Merck & Co., Inc. Arylthiazolidindion- und aryloxazolidinderivate
US6965033B2 (en) * 1999-12-22 2005-11-15 Metabasis Therapeutics, Inc. Bisamidate phosphonate prodrugs
US6818776B2 (en) * 2000-02-01 2004-11-16 Kyorin Pharmaceutical Co., Ltd. Alkali metal salt of thiazolidine-2,4-dione derivative
WO2001081327A1 (fr) 2000-04-25 2001-11-01 Kyorin Pharmaceutical Co., Ltd. Nouveau cristal stable de derive thiazolidinedione et son procede de production
US7563774B2 (en) * 2000-06-29 2009-07-21 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
ITRM20020016A1 (it) * 2002-01-15 2003-07-15 Sigma Tau Ind Farmaceuti Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza
WO2006023515A2 (en) * 2004-08-18 2006-03-02 Metabasis Therapeutics, Inc. Novel thiazole inhibitors of fructose 1,6-bisphosphatase
US8686048B2 (en) * 2010-05-06 2014-04-01 Rhizen Pharmaceuticals Sa Immunomodulator and anti-inflammatory compounds
KR102384153B1 (ko) 2018-01-09 2022-04-06 주식회사 엘지에너지솔루션 이형지 커버를 포함하는 전지팩

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5728073A (en) * 1980-07-29 1982-02-15 Takeda Chem Ind Ltd Inhibitor for aldose reducing enzyme
DE3479419D1 (en) * 1983-01-17 1989-09-21 Pfizer Aldose reductase inhibiting 5-(2-alkoxyphenyl)thiazolidinediones
ATE186724T1 (de) * 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate

Also Published As

Publication number Publication date
US5342850A (en) 1994-08-30
HUT66972A (en) 1995-01-30
DE69227080T2 (de) 1999-05-20
AU1205992A (en) 1992-09-15
CA2081113A1 (en) 1992-08-26
JPH0592960A (ja) 1993-04-16
HU217116B (hu) 1999-11-29
KR960012206B1 (ko) 1996-09-16
HU9203284D0 (en) 1992-12-28
DE69227080D1 (de) 1998-10-29
EP0526658B1 (de) 1998-09-23
CA2081113C (en) 2001-03-06
WO1992014719A1 (en) 1992-09-03
EP0526658A1 (de) 1993-02-10
KR937000469A (ko) 1993-03-15
DK0526658T3 (da) 1999-06-14
AU645886B2 (en) 1994-01-27
JP3053490B2 (ja) 2000-06-19
ES2122991T3 (es) 1999-01-01
EP0526658A4 (en) 1993-04-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee