ES2123549T3 - Derivado de tiazolidina-2,4-diona, sal de dicho derivado y su produccion. - Google Patents

Derivado de tiazolidina-2,4-diona, sal de dicho derivado y su produccion.

Info

Publication number
ES2123549T3
ES2123549T3 ES92905306T ES92905306T ES2123549T3 ES 2123549 T3 ES2123549 T3 ES 2123549T3 ES 92905306 T ES92905306 T ES 92905306T ES 92905306 T ES92905306 T ES 92905306T ES 2123549 T3 ES2123549 T3 ES 2123549T3
Authority
ES
Spain
Prior art keywords
derivative
salt
same
thiazolidine
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92905306T
Other languages
English (en)
Inventor
Michiro Ohnota
Kyuya Okamura
Yoshihiro Hirata
Koji Murakami
Mitsuo Ohashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2123549T3 publication Critical patent/ES2123549T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE PRESENTA UN NUEVO DERIVADO DE LA TIAZOLIDINA-2,4-DIONA CON ACTIVIDAD INHIBITORIA DE LA REDUCTASA DE ALDOSA E HIPOGLICEMICA, REPRESENTADO POR LA FORMULA GENERAL (I), UNA SAL DEL MISMO, UN PROCESO PARA LA PRODUCCION DEL MISMO Y NUEVOS PRODUCTOS FARMACEUTICOS QUE CONTIENEN EL MISMO, EN DONDE R1 Y R2 PUEDEN SER IGUALES O DIFERENTES Y CADA UNA REPRESENTA HIDROGENO, HALOGENO, ALQUIL INFERIOR, HIDROXIDO, ALCOXIDO INFERIOR, NITRO O AMINO QUE PUEDE ESTAR SUBSTITUIDO POR ALQUIL O ALCANOIL INFERIOR; R3 REPRESENTA HIDROGENO O ALQUIL INFERIOR; A REPRESENTA ALQUILENO INFERIOR O CARBONIL; Y B Y W SON DIFERENTES UNA DE LA OTRA Y CADA UNA DE ELLAS REPRESENTA ALQUILENO INFERIOR, CARBONIL O UN ENLACE LIBRE.
ES92905306T 1991-02-25 1992-02-24 Derivado de tiazolidina-2,4-diona, sal de dicho derivado y su produccion. Expired - Lifetime ES2123549T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3053278A JPH04270273A (ja) 1991-02-25 1991-02-25 チアゾリジン−２，４−ジオン誘導体とその塩及びその製造法

Publications (1)

Publication Number Publication Date
ES2123549T3 true ES2123549T3 (es) 1999-01-16

Family

ID=12938273

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92905306T Expired - Lifetime ES2123549T3 (es) 1991-02-25 1992-02-24 Derivado de tiazolidina-2,4-diona, sal de dicho derivado y su produccion.

Country Status (13)

Country Link
US (1) US5308856A (es)
EP (1) EP0527232B1 (es)
JP (1) JPH04270273A (es)
KR (1) KR960007533B1 (es)
AT (1) ATE171450T1 (es)
AU (1) AU645177B2 (es)
CA (1) CA2081112A1 (es)
DE (1) DE69227081T2 (es)
DK (1) DK0527232T3 (es)
ES (1) ES2123549T3 (es)
HU (1) HU218662B (es)
TW (1) TW202447B (es)
WO (1) WO1992014730A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3906935B2 (ja) * 1995-12-18 2007-04-18 杏林製薬株式会社 Ｎ−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法
EP1253145B1 (en) * 2000-02-01 2006-09-20 Kyorin Pharmaceutical Co., Ltd. Alkali metal salt of thiazolidine-2,4-dione derivatives
EP1277745A4 (en) 2000-04-25 2004-09-15 Kyorin Seiyaku Kk NEW STABLE CRYSTALS OF THIAZOLIDINDION DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
EP2124562B1 (en) 2007-03-09 2016-04-20 Second Genome, Inc. Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5728073A (en) * 1980-07-29 1982-02-15 Takeda Chem Ind Ltd Inhibitor for aldose reducing enzyme
JPS5748983A (en) * 1980-09-05 1982-03-20 Takeda Chem Ind Ltd Thiazoldine derivative
JPS6419077A (en) * 1987-07-13 1989-01-23 Yamanouchi Pharma Co Ltd Thiazolidine derivative

Also Published As

Publication number Publication date
HUT67173A (en) 1995-02-28
EP0527232A1 (en) 1993-02-17
DE69227081T2 (de) 1999-05-20
EP0527232B1 (en) 1998-09-23
ATE171450T1 (de) 1998-10-15
DE69227081D1 (de) 1998-10-29
DK0527232T3 (da) 1999-06-14
HU218662B (hu) 2000-10-28
AU645177B2 (en) 1994-01-06
US5308856A (en) 1994-05-03
HU9203293D0 (en) 1992-12-28
EP0527232A4 (en) 1993-04-21
JPH04270273A (ja) 1992-09-25
AU1246092A (en) 1992-09-15
KR960007533B1 (ko) 1996-06-05
CA2081112A1 (en) 1992-08-26
TW202447B (es) 1993-03-21
WO1992014730A1 (en) 1992-09-03

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