ES2101802T3 - Ensayo para determinar los niveles de igf-i, igf-ii y gh libres en liquidos corporales. - Google Patents

Ensayo para determinar los niveles de igf-i, igf-ii y gh libres en liquidos corporales.

Info

Publication number
ES2101802T3
ES2101802T3 ES92300306T ES92300306T ES2101802T3 ES 2101802 T3 ES2101802 T3 ES 2101802T3 ES 92300306 T ES92300306 T ES 92300306T ES 92300306 T ES92300306 T ES 92300306T ES 2101802 T3 ES2101802 T3 ES 2101802T3
Authority
ES
Spain
Prior art keywords
igf
free
levels
capture reagent
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92300306T
Other languages
English (en)
Inventor
Venkat R Mukku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2101802T3 publication Critical patent/ES2101802T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/61—Growth hormones [GH] (Somatotropin)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

SE DESCRIBE UN METODO Y ESTUCHE CON EQUIPO PARA DETERMINAR NIVELES, EN MUESTRA BIOLOGICAS, DE LIGANDOS LIBRES IGF-I, IGF-II Y GH, QUE ESTAN NORMALMENTE ASOCIADOS EN LA MUESTRA CON UNA PROTEINA DE ENLACE. ESTE METODO IMPLICA LA PUESTA EN CONTACTO DEL FLUIDO CORPORAL CON UN REACTIVO DE CAPTURA NO-ETIQUETADO INMOVILIZADO Y SU INCUBACION A 4-10 C DURANTE NO MAS DE 4 HORAS PARA ENLAZAR EL LIGANTE LIBRE CONTENIDO EN EL FLUIDO CORPORAL; LA SEPARACION DEL FLUIDO DEL REACTIVO DE CAPTURA INMOVILIZADO; Y LA DETERMINACION DEL NIVEL DEL LIGANTE LIBRE AHORA ENLAZADO AL REACTIVO DE CAPTURA. ESTE METODO ES PARTICULARMENTE UTIL PARA DETERMINAR NIVELES DE IGF-I LIBRE EN SUERO O PLASMA.
ES92300306T 1991-01-17 1992-01-14 Ensayo para determinar los niveles de igf-i, igf-ii y gh libres en liquidos corporales. Expired - Lifetime ES2101802T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/642,509 US5198340A (en) 1991-01-17 1991-01-17 Assay for free igf-i, igf-ii, and gh levels in body fluids

Publications (1)

Publication Number Publication Date
ES2101802T3 true ES2101802T3 (es) 1997-07-16

Family

ID=24576872

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92300306T Expired - Lifetime ES2101802T3 (es) 1991-01-17 1992-01-14 Ensayo para determinar los niveles de igf-i, igf-ii y gh libres en liquidos corporales.

Country Status (7)

Country Link
US (1) US5198340A (es)
EP (1) EP0495625B1 (es)
AT (1) ATE151883T1 (es)
DE (1) DE69218981T2 (es)
DK (1) DK0495625T3 (es)
ES (1) ES2101802T3 (es)
GR (1) GR3024052T3 (es)

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US5747273A (en) * 1996-05-07 1998-05-05 Diagnostic Systems Laboratories, Inc. Immunoassay of total insulin-like growth factor binding protein-1
US6066464A (en) * 1996-12-10 2000-05-23 Diagnostic Systems Laboratories, Inc. Immunoassay of IGF family of peptides, their binding proteins and related molecules in dried whole blood filter paper spots
US5824467A (en) * 1997-02-25 1998-10-20 Celtrix Pharmaceuticals Methods for predicting drug response
US6200762B1 (en) 1997-08-01 2001-03-13 Aurora Biosciences Corporation Photon reducing agents and compositions for fluorescence assays
US6221612B1 (en) * 1997-08-01 2001-04-24 Aurora Biosciences Corporation Photon reducing agents for use in fluorescence assays
US6214563B1 (en) 1997-08-01 2001-04-10 Aurora Biosciences Corporation Photon reducing agents for reducing undesired light emission in assays
US6394952B1 (en) * 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
EP2316922B1 (en) * 2002-05-24 2013-05-22 Merck Sharp & Dohme Corp. Neutralizing human anti-IGFR antibody
EP2386862A1 (en) * 2002-10-09 2011-11-16 DMI Biosciences, Inc. Methods and kits for diagnosing appendicitis
CN102861321A (zh) 2003-09-12 2013-01-09 特西卡股份有限公司 胰岛素样生长因子-1(igf-1)缺陷的治疗方法
US7169560B2 (en) * 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
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AR046639A1 (es) * 2003-11-21 2005-12-14 Schering Corp Combinaciones terapeuticas de anticuerpo anti- igfr1
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PT1828249E (pt) * 2004-12-03 2011-02-25 Schering Corp Biomarcadores para a pré-selecção de pacientes para terapêutica anti-igf1r
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BRPI0608777A2 (pt) * 2005-04-15 2010-01-26 Schering Corp métodos para tratamento ou prevenção de cáncer, bem como uso de inibidores de igf1r na preparação de composições farmacêuticas
US20060286103A1 (en) * 2005-06-15 2006-12-21 Parag Kolhe Stable antibody formulation
CN114544978A (zh) * 2022-03-04 2022-05-27 美康生物科技股份有限公司 一种igf-1检测试剂盒及其制备方法和检测方法
CN116087386A (zh) * 2023-04-11 2023-05-09 西湖欧米(杭州)生物科技有限公司 一种人胰岛素样生长因子检测方法及试剂盒

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Also Published As

Publication number Publication date
EP0495625B1 (en) 1997-04-16
GR3024052T3 (en) 1997-10-31
EP0495625A3 (en) 1993-04-07
EP0495625A2 (en) 1992-07-22
DE69218981D1 (de) 1997-05-22
US5198340A (en) 1993-03-30
DE69218981T2 (de) 1997-09-25
ATE151883T1 (de) 1997-05-15
DK0495625T3 (da) 1997-10-06

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