ES2096735T3 - Profarmacos glucosilados, su procedimiento de preparacion y su utilizacion. - Google Patents

Profarmacos glucosilados, su procedimiento de preparacion y su utilizacion.

Info

Publication number
ES2096735T3
ES2096735T3 ES92401218T ES92401218T ES2096735T3 ES 2096735 T3 ES2096735 T3 ES 2096735T3 ES 92401218 T ES92401218 T ES 92401218T ES 92401218 T ES92401218 T ES 92401218T ES 2096735 T3 ES2096735 T3 ES 2096735T3
Authority
ES
Spain
Prior art keywords
promarces
glucosilated
preparation procedure
prodrugs
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92401218T
Other languages
English (en)
Inventor
Jean-Claude Jacquesy
Jean-Pierre Gesson
Claude Monneret
Martine Mondon
Brigitte Renoux
Jean-Claude Florent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Sanofi Aventis France
Original Assignee
Behringwerke AG
Laboratoires Hoechst SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG, Laboratoires Hoechst SA filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2096735T3 publication Critical patent/ES2096735T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)

Abstract

PRODROGAS GLICOLIZADAS, PROCESO PARA SU PREPARACION Y SU USO CON CONJUGADOS INMUNOENZIMATICOS ESPECIFICOS DE TUMORES, EN EL TRATAMIENTO DE LOS CANCERES. ESTAS PRODROGAS DE ANTRACICLINAS RESPONDEN A LA SIGUIENTE FORMULA (I):
ES92401218T 1991-04-30 1992-04-29 Profarmacos glucosilados, su procedimiento de preparacion y su utilizacion. Expired - Lifetime ES2096735T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105326A FR2676058B1 (fr) 1991-04-30 1991-04-30 Prodrogues glycosylees, leur procede de preparation et leur utilisation dans le traitement des cancers.

Publications (1)

Publication Number Publication Date
ES2096735T3 true ES2096735T3 (es) 1997-03-16

Family

ID=9412404

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92401218T Expired - Lifetime ES2096735T3 (es) 1991-04-30 1992-04-29 Profarmacos glucosilados, su procedimiento de preparacion y su utilizacion.

Country Status (16)

Country Link
US (1) US5561119A (es)
EP (1) EP0511917B1 (es)
JP (1) JP3053646B2 (es)
KR (1) KR100254113B1 (es)
AT (1) ATE144523T1 (es)
AU (1) AU673138B2 (es)
CA (1) CA2109304C (es)
DE (1) DE69214712T2 (es)
DK (1) DK0511917T3 (es)
ES (1) ES2096735T3 (es)
FR (1) FR2676058B1 (es)
GR (1) GR3022344T3 (es)
HK (1) HK1008020A1 (es)
IE (1) IE921369A1 (es)
UA (1) UA56981C2 (es)
WO (1) WO1992019639A1 (es)

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Also Published As

Publication number Publication date
CA2109304A1 (en) 1992-10-31
GR3022344T3 (en) 1997-04-30
FR2676058B1 (fr) 1994-02-25
WO1992019639A1 (fr) 1992-11-12
DE69214712T2 (de) 1997-05-07
ATE144523T1 (de) 1996-11-15
AU673138B2 (en) 1996-10-31
HK1008020A1 (en) 1999-04-30
UA56981C2 (uk) 2003-06-16
AU1778892A (en) 1992-12-21
FR2676058A1 (fr) 1992-11-06
JP3053646B2 (ja) 2000-06-19
CA2109304C (en) 2002-01-15
DE69214712D1 (de) 1996-11-28
US5561119A (en) 1996-10-01
DK0511917T3 (da) 1997-04-01
IE921369A1 (en) 1992-11-04
EP0511917B1 (fr) 1996-10-23
EP0511917A1 (fr) 1992-11-04
KR100254113B1 (ko) 2000-04-15
JPH06506687A (ja) 1994-07-28

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