HK1008020A1 - Glycosylated prodrugs process for their preparation and uses thereof - Google Patents

Glycosylated prodrugs process for their preparation and uses thereof

Info

Publication number
HK1008020A1
HK1008020A1 HK98107056A HK98107056A HK1008020A1 HK 1008020 A1 HK1008020 A1 HK 1008020A1 HK 98107056 A HK98107056 A HK 98107056A HK 98107056 A HK98107056 A HK 98107056A HK 1008020 A1 HK1008020 A1 HK 1008020A1
Authority
HK
Hong Kong
Prior art keywords
preparation
glycosylated prodrugs
prodrugs
glycosylated
tumor
Prior art date
Application number
HK98107056A
Other languages
English (en)
Inventor
Jean-Claude Jacquesy
Jean-Pierre Gesson
Claude Monneret
Martine Mondon
Brigitte Renoux
Jean-Claude Florent
Michel Koch
Francois Tillequin
Hans Harald Sedlacek
Manfred Gerken
Cenek Kolar
Gilbert Gaudel
Klaus Bosslet
Jorg Czech
Dieter Hoffman
Gerhard Seeman
Hans-Ulrich Schorlemmer
Gerhard Dickneite
Original Assignee
Hoechst Sa Lab
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Sa Lab, Behringwerke Ag filed Critical Hoechst Sa Lab
Publication of HK1008020A1 publication Critical patent/HK1008020A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
HK98107056A 1991-04-30 1998-06-26 Glycosylated prodrugs process for their preparation and uses thereof HK1008020A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105326A FR2676058B1 (fr) 1991-04-30 1991-04-30 Prodrogues glycosylees, leur procede de preparation et leur utilisation dans le traitement des cancers.

Publications (1)

Publication Number Publication Date
HK1008020A1 true HK1008020A1 (en) 1999-04-30

Family

ID=9412404

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98107056A HK1008020A1 (en) 1991-04-30 1998-06-26 Glycosylated prodrugs process for their preparation and uses thereof

Country Status (16)

Country Link
US (1) US5561119A (xx)
EP (1) EP0511917B1 (xx)
JP (1) JP3053646B2 (xx)
KR (1) KR100254113B1 (xx)
AT (1) ATE144523T1 (xx)
AU (1) AU673138B2 (xx)
CA (1) CA2109304C (xx)
DE (1) DE69214712T2 (xx)
DK (1) DK0511917T3 (xx)
ES (1) ES2096735T3 (xx)
FR (1) FR2676058B1 (xx)
GR (1) GR3022344T3 (xx)
HK (1) HK1008020A1 (xx)
IE (1) IE921369A1 (xx)
UA (1) UA56981C2 (xx)
WO (1) WO1992019639A1 (xx)

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Also Published As

Publication number Publication date
ATE144523T1 (de) 1996-11-15
GR3022344T3 (en) 1997-04-30
ES2096735T3 (es) 1997-03-16
DE69214712T2 (de) 1997-05-07
CA2109304C (en) 2002-01-15
JP3053646B2 (ja) 2000-06-19
JPH06506687A (ja) 1994-07-28
EP0511917A1 (fr) 1992-11-04
DE69214712D1 (de) 1996-11-28
EP0511917B1 (fr) 1996-10-23
AU673138B2 (en) 1996-10-31
FR2676058B1 (fr) 1994-02-25
CA2109304A1 (en) 1992-10-31
DK0511917T3 (da) 1997-04-01
FR2676058A1 (fr) 1992-11-06
AU1778892A (en) 1992-12-21
UA56981C2 (uk) 2003-06-16
IE921369A1 (en) 1992-11-04
US5561119A (en) 1996-10-01
WO1992019639A1 (fr) 1992-11-12
KR100254113B1 (ko) 2000-04-15

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Legal Events

Date Code Title Description
PF Patent in force
AS Change of ownership

Owner name: AVENTIS PHARMA S.A., BEHRINGWERKE AKTIENGESELLSCHA

Free format text: FORMER OWNER(S): HOECHST MARION ROUSSEL, BEHRINGWERKE AKTIENGESELLSCHAFT ?

PE Patent expired

Effective date: 20120428