ES2095233T3 - Produccion eficaz de proteasa mutante. - Google Patents

Produccion eficaz de proteasa mutante.

Info

Publication number
ES2095233T3
ES2095233T3 ES90202109T ES90202109T ES2095233T3 ES 2095233 T3 ES2095233 T3 ES 2095233T3 ES 90202109 T ES90202109 T ES 90202109T ES 90202109 T ES90202109 T ES 90202109T ES 2095233 T3 ES2095233 T3 ES 2095233T3
Authority
ES
Spain
Prior art keywords
effective production
mutant protease
chains
mutant
bacillus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90202109T
Other languages
English (en)
Inventor
Der Laan Johannes Cornelis Van
Eekelen Christiaan Albertu Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8202457&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2095233(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Application granted granted Critical
Publication of ES2095233T3 publication Critical patent/ES2095233T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Mushroom Cultivation (AREA)

Abstract

LAS CADENAS DE BACILLUS ALCALOFILICOS PRODUCEN DE MANERA EFICIENTE PROTEASAS DE BACILLUS MUTANTE Y LOS CUALES SON INCAPACES DE EXPRESAR LAS PROTEASAS TIPO VIRGEN. TAMBIEN DESCRITOS LOS METODOS DE OBTENCION DE TALES CADENAS DE BACILLUS.
ES90202109T 1989-08-11 1990-08-02 Produccion eficaz de proteasa mutante. Expired - Lifetime ES2095233T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89202117 1989-08-11

Publications (1)

Publication Number Publication Date
ES2095233T3 true ES2095233T3 (es) 1997-02-16

Family

ID=8202457

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90202109T Expired - Lifetime ES2095233T3 (es) 1989-08-11 1990-08-02 Produccion eficaz de proteasa mutante.

Country Status (19)

Country Link
US (1) US20040014175A1 (es)
EP (1) EP0414297B1 (es)
JP (1) JP3490435B2 (es)
KR (1) KR0169978B1 (es)
CN (1) CN1049866A (es)
AT (1) ATE144283T1 (es)
AU (1) AU629970B2 (es)
BG (1) BG60567B1 (es)
BR (1) BR9003956A (es)
CA (1) CA2023094C (es)
DD (1) DD297187A5 (es)
DE (1) DE69028890T2 (es)
DK (1) DK0414297T3 (es)
ES (1) ES2095233T3 (es)
FI (1) FI110365B (es)
GR (1) GR3021669T3 (es)
IE (1) IE77037B1 (es)
PT (1) PT94961B (es)
RU (1) RU2060276C1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4304161A1 (de) * 1993-02-12 1994-08-25 Solvay Enzymes Gmbh & Co Kg Verbesserte hochalkalische Proteasen
WO1995035382A2 (en) 1994-06-17 1995-12-28 Genecor International Inc. NOVEL AMYLOLYTIC ENZYMES DERIVED FROM THE B. LICHENIFORMIS α-AMYLASE, HAVING IMPROVED CHARACTERISTICS
EP0894126B1 (en) * 1996-03-27 2006-02-01 Novozymes A/S Alkaline protease deficient filamentous fungi
JP3440694B2 (ja) * 1996-05-16 2003-08-25 ライオン株式会社 口腔用組成物
GB0024554D0 (en) 2000-10-06 2000-11-22 Agrol Ltd Ethanol production
AU2003228393A1 (en) 2002-03-29 2003-10-13 Genencor International, Inc. Ehanced protein expression in bacillus
JP5063366B2 (ja) 2005-02-16 2012-10-31 ザ ジェネラル ホスピタル コーポレイション ヘプシジンによる鉄代謝を制御するためのＴＧＦ−βスーパーファミリーの化合物の調節因子の使用
RU2510821C1 (ru) * 2012-10-24 2014-04-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) Штамм бактерий bacillus pumilus мк-10 с низкой протеолитической активностью и его применение
RU2511416C1 (ru) * 2012-10-24 2014-04-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) федеральный университет" (ФГАО ВПО КФУ) Штамм бактерий bacillus pumilus 2a-5 с низкой протеолитической активностью, повышенной активностью фосфатазы, способ его получения и применения

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234445A (es) * 1967-10-03 1971-06-03
JPS6055118B2 (ja) * 1982-02-08 1985-12-03 昭和電工株式会社 新規な細菌アルカリプロテア−ゼ及びその製造方法
IE81141B1 (en) * 1983-06-24 2000-04-05 Genencor Int Procaryotic carbonyl hydrolases
US4828994A (en) * 1984-09-21 1989-05-09 Genex Corporation Bacillus strains with reduced extracellular protease levels
JP2637532B2 (ja) * 1987-02-27 1997-08-06 ギスト ブロカデス ナームローゼ フェンノートチャップ 原核微生物の染色体ｄｎａにおける安定した遺伝子増幅
ES2135386T3 (es) * 1987-02-27 1999-11-01 Genencor Int Transformacion de cepas de bacillus alcalofilas.
CN1056187C (zh) * 1988-02-11 2000-09-06 金克克国际有限公司 新的蛋白水解酶及其在洗涤剂中的应用

Also Published As

Publication number Publication date
BR9003956A (pt) 1991-09-03
DD297187A5 (de) 1992-01-02
IE902904A1 (en) 1991-02-27
RU2060276C1 (ru) 1996-05-20
CA2023094C (en) 2000-03-28
ATE144283T1 (de) 1996-11-15
EP0414297A1 (en) 1991-02-27
PT94961A (pt) 1991-04-18
BG92653A (bg) 1993-12-24
AU629970B2 (en) 1992-10-15
EP0414297B1 (en) 1996-10-16
DE69028890T2 (de) 1997-02-27
KR0169978B1 (ko) 1999-02-01
CA2023094A1 (en) 1991-02-12
JPH03210177A (ja) 1991-09-13
GR3021669T3 (en) 1997-02-28
PT94961B (pt) 1997-05-28
FI110365B (fi) 2002-12-31
BG60567B1 (bg) 1995-08-28
DK0414297T3 (da) 1997-07-07
FI903927A0 (fi) 1990-08-08
AU6096190A (en) 1991-02-14
KR910004805A (ko) 1991-03-29
US20040014175A1 (en) 2004-01-22
JP3490435B2 (ja) 2004-01-26
CN1049866A (zh) 1991-03-13
DE69028890D1 (de) 1996-11-21
IE77037B1 (en) 1997-11-19

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