DK1141337T3 - Gram-positive bakterier, som mangler HtrA-proteaseaktivitet, samt deres anvendelser - Google Patents

Gram-positive bakterier, som mangler HtrA-proteaseaktivitet, samt deres anvendelser

Info

Publication number
DK1141337T3
DK1141337T3 DK99961158.5T DK99961158T DK1141337T3 DK 1141337 T3 DK1141337 T3 DK 1141337T3 DK 99961158 T DK99961158 T DK 99961158T DK 1141337 T3 DK1141337 T3 DK 1141337T3
Authority
DK
Denmark
Prior art keywords
gram
positive bacteria
applications
well
protease activity
Prior art date
Application number
DK99961158.5T
Other languages
English (en)
Inventor
Isabelle Poquet
Alexandre Bolotine
Alexei Sorokine
Alexandra Gruss
Original Assignee
Agronomique Inst Nat Rech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agronomique Inst Nat Rech filed Critical Agronomique Inst Nat Rech
Application granted granted Critical
Publication of DK1141337T3 publication Critical patent/DK1141337T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99961158.5T 1998-12-24 1999-12-23 Gram-positive bakterier, som mangler HtrA-proteaseaktivitet, samt deres anvendelser DK1141337T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9816462A FR2787810B1 (fr) 1998-12-24 1998-12-24 Bacteries a gram positif depourvues d'activite proteasique htra, et leurs utilisations
PCT/FR1999/003270 WO2000039309A1 (fr) 1998-12-24 1999-12-23 BACTERIES A GRAM POSITIF DEPOURVUES D'ACTIVITE PROTEASIQUE HtrA, ET LEURS UTILISATIONS

Publications (1)

Publication Number Publication Date
DK1141337T3 true DK1141337T3 (da) 2011-03-14

Family

ID=9534523

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99961158.5T DK1141337T3 (da) 1998-12-24 1999-12-23 Gram-positive bakterier, som mangler HtrA-proteaseaktivitet, samt deres anvendelser

Country Status (11)

Country Link
US (2) US6994997B1 (da)
EP (1) EP1141337B1 (da)
AT (1) ATE489468T1 (da)
AU (1) AU1786300A (da)
CA (1) CA2356740C (da)
DE (1) DE69942984D1 (da)
DK (1) DK1141337T3 (da)
ES (1) ES2357187T3 (da)
FR (1) FR2787810B1 (da)
PT (1) PT1141337E (da)
WO (1) WO2000039309A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL156111A0 (en) 2000-12-14 2003-12-23 Genentech Inc Bacterial host strains
CN102740867A (zh) 2010-01-14 2012-10-17 法国国家健康与医学研究院 用于预防和治疗炎症性肠病(ibd)和肠易激综合征(ibs)的重组益生菌
IL214246B (en) * 2011-07-21 2018-08-30 Shafferman Avigdor Vaccines produced from htra-defective Bacillus anthraxis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE122391T1 (de) * 1987-01-30 1995-05-15 Harvard College Periplasmische protease-mutanten von escherichia coli.
NL8902010A (nl) * 1989-08-04 1991-03-01 Nl Zuivelonderzoek Inst Dna-fragment met ten minste een protease-gen, een dergelijk dna-fragment bevattende cloneringsvektor, een gastheercel getransformeerd met een dusdanig opgebouwde cloneringsvektor, alsmede de met dergelijke gastheercellen geproduceerde proteasen resp. bereide produkten zoals voedingsmiddelen.
GB9007194D0 (en) * 1990-03-30 1990-05-30 Wellcome Found Live vaccines
US5159517A (en) * 1990-07-17 1992-10-27 Innovative Designer Products, Inc. Immersion detection circuit interrupter
US5264365A (en) * 1990-11-09 1993-11-23 Board Of Regents, The University Of Texas System Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides
DE69737854D1 (de) * 1996-04-15 2007-08-09 Friesland Brands Bv Verfahren zur herstellung von milchprodukten, insbesondere käse, unter verwendung von milchsäurebakterien die mit zusätzlicher neutraler proteaseaktivität ausgestattet sind

Also Published As

Publication number Publication date
ATE489468T1 (de) 2010-12-15
FR2787810B1 (fr) 2002-10-31
US20060228377A1 (en) 2006-10-12
DE69942984D1 (de) 2011-01-05
EP1141337B1 (fr) 2010-11-24
CA2356740C (fr) 2013-11-12
AU1786300A (en) 2000-07-31
FR2787810A1 (fr) 2000-06-30
PT1141337E (pt) 2011-02-09
ES2357187T3 (es) 2011-04-19
WO2000039309A1 (fr) 2000-07-06
CA2356740A1 (fr) 2000-07-06
EP1141337A1 (fr) 2001-10-10
US6994997B1 (en) 2006-02-07

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