ES2079490T3 - Procedimiento para preparar dispersiones acuosas. - Google Patents

Procedimiento para preparar dispersiones acuosas.

Info

Publication number
ES2079490T3
ES2079490T3 ES90915081T ES90915081T ES2079490T3 ES 2079490 T3 ES2079490 T3 ES 2079490T3 ES 90915081 T ES90915081 T ES 90915081T ES 90915081 T ES90915081 T ES 90915081T ES 2079490 T3 ES2079490 T3 ES 2079490T3
Authority
ES
Spain
Prior art keywords
aqueous dispersions
procedure
preparing aqueous
multiphase
liquids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90915081T
Other languages
English (en)
Inventor
Georg Rossling
Andreas Sachse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2079490T3 publication Critical patent/ES2079490T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/36Pervaporation; Membrane distillation; Liquid permeation
    • B01D61/364Membrane distillation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461Dispersions, colloids, emulsions or suspensions
    • A61K49/0466Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/36Pervaporation; Membrane distillation; Liquid permeation
    • B01D61/362Pervaporation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Steroid Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA DESCRIPCION SE REFIERE A UN PROCESO PARA HACER DISPERSIONES ACUOSAS EN QUE LOS LIQUIDOS SON RETIRADOS DE UNA MEZCLA LIQUIDA POSIBLEMENTE MULTIFASE MEDIANTE LA DESTILACION POR DIAFRAGMA.
ES90915081T 1989-10-13 1990-10-05 Procedimiento para preparar dispersiones acuosas. Expired - Lifetime ES2079490T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3934656A DE3934656A1 (de) 1989-10-13 1989-10-13 Verfahren zur herstellung von waessrigen dispersionen

Publications (1)

Publication Number Publication Date
ES2079490T3 true ES2079490T3 (es) 1996-01-16

Family

ID=6391657

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90915081T Expired - Lifetime ES2079490T3 (es) 1989-10-13 1990-10-05 Procedimiento para preparar dispersiones acuosas.

Country Status (16)

Country Link
US (2) US5110475A (es)
EP (1) EP0451236B1 (es)
JP (1) JPH04502124A (es)
AT (1) ATE127708T1 (es)
AU (1) AU648043B2 (es)
CA (1) CA2027527A1 (es)
DE (2) DE3934656A1 (es)
DK (1) DK0451236T3 (es)
ES (1) ES2079490T3 (es)
FI (1) FI103953B1 (es)
GR (1) GR900100751A (es)
HU (1) HUT57632A (es)
IE (1) IE70758B1 (es)
NO (1) NO177956C (es)
PT (1) PT95576B (es)
WO (1) WO1991005599A1 (es)

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US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US20010024638A1 (en) * 1992-11-02 2001-09-27 Michel Schneider Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
IN172208B (es) 1990-04-02 1993-05-01 Sint Sa
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
DE4122661C2 (de) * 1990-08-06 1996-07-11 Nattermann A & Cie Pharmazeutisches Produkt zur Behandlung von Pneumocystis-carinii-Pneumonie
FR2684367B1 (fr) * 1991-12-02 1994-03-11 Hoechst Ste Fse Procede d'obtention d'un sol de silice disperse dans un alcanol inferieur et application de l'organosol ainsi obtenu, notamment a la preparation de compositions de revetement de surface de verre organique.
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
CA2146963A1 (en) * 1992-10-16 1994-04-28 Andreas Sachse Process and device for producing liquid, dispersed systems
ZA94614B (en) * 1993-02-11 1994-08-12 Sasol Chem Ind Pty Solvent extraction
CZ128096A3 (en) * 1993-11-04 1997-08-13 Schering Ag Charged liposome preparation
DE4341472A1 (de) * 1993-12-02 1995-06-08 Schering Ag Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen
CN1068229C (zh) * 1993-12-15 2001-07-11 勃勒柯研究有限公司 超声对比介质、含该介质的对比剂及方法
FR2716111B1 (fr) * 1994-02-11 1996-11-08 Cogia Procédé de préparation d'une composition cosmétique ou alimentaire apte à être conservée, dispositif et composition de longue conservation.
AU4789096A (en) * 1995-02-09 1996-08-27 Schering Aktiengesellschaft Liposomes containing contrast media for blood pool imaging
US6726650B2 (en) 1997-12-04 2004-04-27 Bracco Research S.A. Automatic liquid injection system and method
US6075073A (en) * 1998-08-20 2000-06-13 Apex Medical Technologies, Inc. Latices from emulsified hydrocarbon rubber solutions by membrane separation
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
CN1190454C (zh) * 2000-04-28 2005-02-23 田边制药株式会社 用于制备微球的方法
AU2002322284A1 (en) * 2001-06-25 2003-01-08 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
US6991727B2 (en) * 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
WO2003075892A1 (en) 2002-03-13 2003-09-18 Novartis Ag Pharmaceutical microparticles
WO2005044783A2 (en) * 2003-11-04 2005-05-19 Lonza Ag Acetonitrile recycling process
WO2005075449A1 (en) * 2004-02-03 2005-08-18 Yale University Compounds and methods to increase anti-p-glycoprotein activity of baicalein by alkylation on the a ring
US7871520B2 (en) * 2007-12-18 2011-01-18 Milton Roy Company High-temperature membrane distillation
US9445975B2 (en) * 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
CA2739887A1 (en) * 2008-10-10 2010-04-15 Teva Women's Health, Inc. Methods for treating vasomotor symptoms in castrated prostatic cancer patients with low dose cyproterone acetate
US20100167306A1 (en) * 2008-12-26 2010-07-01 Henry John Smith Rapid test for glycated albumin in saliva
US9492594B2 (en) * 2014-07-18 2016-11-15 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US11406742B2 (en) 2014-07-18 2022-08-09 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
EP3391909A1 (en) * 2017-04-19 2018-10-24 Tiofarma B.V. Aqueous suspension comprising mixed micelles loaded with a lipophilic physiologically active substance
WO2023242329A1 (en) 2022-06-17 2023-12-21 Quantoom Biosciences S.A. Method and device for the production of a carrier

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2386826A (en) * 1942-01-10 1945-10-16 Sylvania Ind Corp Process and apparatus for treating fluid compositions
US3035060A (en) * 1957-06-18 1962-05-15 Standard Oil Co Process for removing water from organic chemicals
US4199445A (en) * 1970-06-16 1980-04-22 Monsanto Company Process for separating aqueous mineral acid mixtures
CH641682A5 (en) * 1978-10-05 1984-03-15 Daeniker Felix X-ray contrast medium
JPS57212232A (en) * 1981-06-24 1982-12-27 Asahi Chem Ind Co Ltd Composite hydrophilic membrane and its preparation
JPS5892407A (ja) * 1981-11-27 1983-06-01 Asahi Glass Co Ltd 液体混合物の分離方法
JPS5892404A (ja) * 1981-11-27 1983-06-01 Asahi Glass Co Ltd 液体混合物の分離方法
JPS5892408A (ja) * 1981-11-27 1983-06-01 Asahi Glass Co Ltd 液体混合物の分離方法
US4744989A (en) * 1984-02-08 1988-05-17 E. R. Squibb & Sons, Inc. Method of preparing liposomes and products produced thereby
GB2157283B (en) * 1984-03-30 1987-07-08 Squibb & Sons Inc Esters of 3,5-diacetylamino-2,4,6-triiodobenzoic acid as x-ray contrast agents
US4728429A (en) * 1985-06-27 1988-03-01 Israel Cabasso Membrane permeation process for dehydration of organic liquid mixtures using sulfonated ion-exchange polyalkene membranes
US4957729A (en) * 1985-09-10 1990-09-18 The University Of Michigan Polyiodinated triglyceride analogs as radiologic agents
DE3610011A1 (de) * 1986-03-25 1987-10-08 Geesthacht Gkss Forschung Verfahren zur trennung der komponenten eines fluessigkeitsgemisches voneinander
US4935144A (en) * 1987-09-17 1990-06-19 Texaco Inc. Concentration of water-ketone compositions
JP2713718B2 (ja) * 1988-03-03 1998-02-16 日本レダリー株式会社 リポソーム調製法
US4798674A (en) * 1988-03-10 1989-01-17 Texaco Inc. Separation of organic liquids
US4877529A (en) * 1988-03-10 1989-10-31 Texaco Inc. Separation of organic liquids
US4952751A (en) * 1988-04-08 1990-08-28 Membrane Technology & Research, Inc. Treatment of evaporator condensates by pervaporation

Also Published As

Publication number Publication date
ATE127708T1 (de) 1995-09-15
DK0451236T3 (da) 1996-02-05
FI912801A0 (fi) 1991-06-11
FI103953B (fi) 1999-10-29
DE59009658D1 (de) 1995-10-19
CA2027527A1 (en) 1991-04-14
US5593687A (en) 1997-01-14
PT95576A (pt) 1991-09-13
IE903653A1 (en) 1991-04-24
EP0451236A1 (de) 1991-10-16
NO177956C (no) 1995-12-27
HU907429D0 (en) 1991-10-28
DE3934656A1 (de) 1991-04-18
AU648043B2 (en) 1994-04-14
WO1991005599A1 (de) 1991-05-02
NO912260D0 (no) 1991-06-12
NO912260L (no) 1991-06-12
IE70758B1 (en) 1996-12-30
EP0451236B1 (de) 1995-09-13
NO177956B (no) 1995-09-18
US5110475A (en) 1992-05-05
FI103953B1 (fi) 1999-10-29
AU6460090A (en) 1991-04-18
HUT57632A (en) 1991-12-30
GR900100751A (el) 1992-03-20
PT95576B (pt) 1997-08-29
JPH04502124A (ja) 1992-04-16

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