ES2077554T1 - Formulaciones inyectables acuosas utiles para un radiodiagnostico que comprenden compuestos aromaticos yodados usados como medio de contraste en rayos x. - Google Patents

Formulaciones inyectables acuosas utiles para un radiodiagnostico que comprenden compuestos aromaticos yodados usados como medio de contraste en rayos x.

Info

Publication number
ES2077554T1
ES2077554T1 ES94904159T ES94904159T ES2077554T1 ES 2077554 T1 ES2077554 T1 ES 2077554T1 ES 94904159 T ES94904159 T ES 94904159T ES 94904159 T ES94904159 T ES 94904159T ES 2077554 T1 ES2077554 T1 ES 2077554T1
Authority
ES
Spain
Prior art keywords
radio
compounds used
injectable formulations
including aromatic
aqueous injectable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES94904159T
Other languages
English (en)
Inventor
Ernst Bracco S P A Felder
Haen Christoph Bracco S P A De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco SpA
Original Assignee
Bracco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco SpA filed Critical Bracco SpA
Publication of ES2077554T1 publication Critical patent/ES2077554T1/es
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A FORMULACIONES INYECTABLES, ACUOSAS QUE CONTIENEN UN AGENTE DE CONTRASTE RADIOOPACO UTIL PARA LA FORMACION DE IMAGENES DE RAYOS X DEL CUERPO HUMANO O DE UN ANIMAL. ESTA INVENCION SE REFIERE ESPECIALMENTE A SOLUCIONES INYECTABLES, ACUOSAS DE MEZCLAS DE COMPUESTOS AROMATICOS, IODADOS, NO IONICOS Y SOLUBLES EN AGUA PREFERIBLEMENTE CONSTITUIDOS POR: A) COMPUESTOS QUE COMPRENDEN UN NUCLEO AROMATICO AL MENOS TRIIODO-SUSTITUIDO; B) COMPUESTOS QUE COMPRENDEN AL MENOS DOS NUCLEOS AROMATICOS VARIABLEMENTE UNIDOS ENTRE SI, CADA UNO DE ELLOS AL MENOS TRIIODO-SUSTITUIDO.
ES94904159T 1992-12-24 1993-12-20 Formulaciones inyectables acuosas utiles para un radiodiagnostico que comprenden compuestos aromaticos yodados usados como medio de contraste en rayos x. Pending ES2077554T1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922964A IT1256248B (it) 1992-12-24 1992-12-24 Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x

Publications (1)

Publication Number Publication Date
ES2077554T1 true ES2077554T1 (es) 1995-12-01

Family

ID=11364538

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94904159T Pending ES2077554T1 (es) 1992-12-24 1993-12-20 Formulaciones inyectables acuosas utiles para un radiodiagnostico que comprenden compuestos aromaticos yodados usados como medio de contraste en rayos x.

Country Status (22)

Country Link
US (1) US5695742A (es)
EP (1) EP0675738B1 (es)
JP (1) JP3585233B2 (es)
CN (1) CN1100329A (es)
AT (1) ATE166234T1 (es)
AU (1) AU5833294A (es)
BR (1) BR9307734A (es)
CA (1) CA2152480A1 (es)
CZ (1) CZ165595A3 (es)
DE (2) DE69318727T2 (es)
ES (1) ES2077554T1 (es)
FI (1) FI953124A0 (es)
GR (1) GR950300061T1 (es)
HU (1) HUT72304A (es)
IL (1) IL108158A0 (es)
IS (1) IS4114A (es)
IT (1) IT1256248B (es)
MX (1) MX9400185A (es)
NO (1) NO952533L (es)
PL (1) PL309395A1 (es)
WO (1) WO1994014478A1 (es)
ZA (1) ZA939666B (es)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5686061A (en) * 1994-04-11 1997-11-11 The Board Of Regents Of The University Of Texas System Particulate contrast media derived from non-ionic water soluble contrast agents for CT enhancement of hepatic tumors
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
GB9419206D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
US5575905A (en) * 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
AU6114396A (en) * 1995-06-16 1997-01-15 Biophysica Foundation Formyl derivatives as nonionic contrast media
CA2244209C (en) 1996-01-25 2007-10-23 Schering Aktiengesellschaft Improved concentrated injection and infusion solutions for intravenous administration
DE19648650C2 (de) * 1996-01-29 1998-07-02 Schering Ag Puffersysteme und deren Verwendung zur Stabilisierung pharmazeutischer Zubereitung
DE19627309C2 (de) * 1996-06-27 1999-07-29 Schering Ag Wäßrige injizierbare Formulierungen verwendbar als Kontrastmittel
DE19736472C1 (de) * 1997-08-21 1999-04-22 Bernhard Dr Sixt Verfahren zum Herstellen von weitgehend nebenwirkungsfreien Kontrastmitteln
US6406680B1 (en) * 1999-09-17 2002-06-18 Nycomed Imaging As X-ray contrast agents
SE520688C2 (sv) 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
US6832220B1 (en) * 2000-08-03 2004-12-14 Microsoft Corporation Method and apparatus for file searching, accessing file identifiers from reference page
AU2002359206B2 (en) 2001-12-20 2008-04-10 Bone Support Ab A new bone mineral substitute
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
GB0228410D0 (en) 2002-12-05 2003-01-08 Glaxo Group Ltd Novel Compounds
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
EP1725268B1 (en) * 2004-03-11 2011-10-19 Mallinckrodt LLC X-ray contrast formulation comprising a mixture of iodinated monomer and dimer
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
WO2009005365A1 (en) * 2007-06-29 2009-01-08 Ge Healthcare As Contrast agents
JP5340281B2 (ja) * 2007-07-12 2013-11-13 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
JP2011500533A (ja) * 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
JP2011500531A (ja) * 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
EP2231200A1 (en) * 2007-12-05 2010-09-29 GE Healthcare AS Contrast agents
EP2247314A4 (en) * 2008-02-01 2013-11-27 Univ Boston CATIONIC CONTRASTING AGENTS AND METHOD FOR THEIR USE
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2245004A2 (en) * 2008-02-27 2010-11-03 GE Healthcare AS Contrast agents
EP2245003A2 (en) * 2008-02-27 2010-11-03 GE Healthcare AS Contrast agents
WO2010060941A2 (en) * 2008-11-27 2010-06-03 Ge Healthcare As Contrast agents
US20110256068A1 (en) * 2009-01-09 2011-10-20 Wistand Lars-Goeran Contrast media compositions
EP2230227A1 (en) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
ES2443149T3 (es) 2009-07-07 2014-02-18 Bracco Imaging Spa Proceso para la preparación de un agente de yodación
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
CA2901528C (en) 2013-02-20 2022-07-26 Bone Support Ab Heat-treated, sintered and micronized hydroxyapatite powder for use in a hardenable bone substitute composition
JP6425375B2 (ja) * 2013-10-11 2018-11-21 新光電気工業株式会社 コイル基板及びその製造方法、インダクタ
WO2016123583A1 (en) 2015-01-29 2016-08-04 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
WO2018104228A1 (en) 2016-12-05 2018-06-14 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
WO2023209165A1 (en) 2022-04-29 2023-11-02 Bracco Imaging Spa Process for the preparation of 2,4,6-triiodophenol derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2613172A (en) * 1949-08-10 1952-10-07 American Cystoscope Makers Inc X-ray contrast compositions
CH608189A5 (es) * 1974-12-13 1978-12-29 Savac Ag
NL8002388A (nl) * 1979-05-21 1980-11-25 Mallinckrodt Inc Roentgencontrastmiddel.
FR2511871A1 (fr) * 1981-08-28 1983-03-04 Guerbet Sa Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus
GB8906130D0 (en) * 1989-03-17 1989-05-04 Nycomed As Compositions
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
US5191120A (en) * 1989-12-13 1993-03-02 Mallinckrodt Medical, Inc. Process for preparing nonionic X-ray contrast agents
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
AU5093993A (en) * 1992-09-02 1994-03-29 Mallinckrodt Medical, Inc. Nonionic X-ray contrast agents compositions and methods
US5260478A (en) * 1992-12-08 1993-11-09 Sterling Winthrop Inc. Iodinated aroyloxy carboxamides
NZ250063A (en) * 1992-12-14 1996-03-26 Eastman Kodak Co Iodinated aromatic acid ester derivatives; x-ray contrast compositions
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x

Also Published As

Publication number Publication date
DE675738T1 (de) 1996-02-29
ZA939666B (en) 1994-08-29
NO952533D0 (no) 1995-06-23
EP0675738A1 (en) 1995-10-11
DE69318727T2 (de) 1998-09-17
JPH08505134A (ja) 1996-06-04
HUT72304A (en) 1996-04-29
AU5833294A (en) 1994-07-19
BR9307734A (pt) 1999-08-31
CA2152480A1 (en) 1994-07-07
GR950300061T1 (en) 1995-11-30
DE69318727D1 (de) 1998-06-25
JP3585233B2 (ja) 2004-11-04
WO1994014478A1 (en) 1994-07-07
CZ165595A3 (en) 1995-12-13
IS4114A (is) 1994-06-25
IT1256248B (it) 1995-11-29
FI953124A (fi) 1995-06-22
ITMI922964A1 (it) 1994-06-24
HU9501850D0 (en) 1995-08-28
NO952533L (no) 1995-08-16
ITMI922964A0 (it) 1992-12-24
CN1100329A (zh) 1995-03-22
EP0675738B1 (en) 1998-05-20
PL309395A1 (en) 1995-10-02
US5695742A (en) 1997-12-09
ATE166234T1 (de) 1998-06-15
MX9400185A (es) 1994-07-29
FI953124A0 (fi) 1995-06-22
IL108158A0 (en) 1994-04-12

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