DE69318727T2 - Wässerige einspritzbare Zusammensetzungen verwendbar zur Radiodiagnose enthaltenden jodierten aromatischen Verbindungen zur Verwendung als Röntgenkontrastmittel - Google Patents

Wässerige einspritzbare Zusammensetzungen verwendbar zur Radiodiagnose enthaltenden jodierten aromatischen Verbindungen zur Verwendung als Röntgenkontrastmittel

Info

Publication number
DE69318727T2
DE69318727T2 DE69318727T DE69318727T DE69318727T2 DE 69318727 T2 DE69318727 T2 DE 69318727T2 DE 69318727 T DE69318727 T DE 69318727T DE 69318727 T DE69318727 T DE 69318727T DE 69318727 T2 DE69318727 T2 DE 69318727T2
Authority
DE
Germany
Prior art keywords
pct
contrast agents
radiodiagnostic
aromatic compounds
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69318727T
Other languages
English (en)
Other versions
DE69318727D1 (de
Inventor
Ernst Bracco S P A Felder
Haen Christoph Bracco S P A De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco SpA
Original Assignee
Bracco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco SpA filed Critical Bracco SpA
Publication of DE69318727D1 publication Critical patent/DE69318727D1/de
Application granted granted Critical
Publication of DE69318727T2 publication Critical patent/DE69318727T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69318727T 1992-12-24 1993-12-20 Wässerige einspritzbare Zusammensetzungen verwendbar zur Radiodiagnose enthaltenden jodierten aromatischen Verbindungen zur Verwendung als Röntgenkontrastmittel Expired - Lifetime DE69318727T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI922964A IT1256248B (it) 1992-12-24 1992-12-24 Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
PCT/EP1993/003613 WO1994014478A1 (en) 1992-12-24 1993-12-20 Aqueous injectable formulations useful for radio-diagnosis comprising iodinated aromatic compounds used as x-ray contrast media

Publications (2)

Publication Number Publication Date
DE69318727D1 DE69318727D1 (de) 1998-06-25
DE69318727T2 true DE69318727T2 (de) 1998-09-17

Family

ID=11364538

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69318727T Expired - Lifetime DE69318727T2 (de) 1992-12-24 1993-12-20 Wässerige einspritzbare Zusammensetzungen verwendbar zur Radiodiagnose enthaltenden jodierten aromatischen Verbindungen zur Verwendung als Röntgenkontrastmittel
DE0675738T Pending DE675738T1 (de) 1992-12-24 1993-12-20 Wässerige Einspritzbare Zusammensetzungen verwendbar zur Radiodiagnose enthaltendenJodierten Aromatischen Verbindungen zur VerwendungalsRöntgenkontrastmittel.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0675738T Pending DE675738T1 (de) 1992-12-24 1993-12-20 Wässerige Einspritzbare Zusammensetzungen verwendbar zur Radiodiagnose enthaltendenJodierten Aromatischen Verbindungen zur VerwendungalsRöntgenkontrastmittel.

Country Status (22)

Country Link
US (1) US5695742A (de)
EP (1) EP0675738B1 (de)
JP (1) JP3585233B2 (de)
CN (1) CN1100329A (de)
AT (1) ATE166234T1 (de)
AU (1) AU5833294A (de)
BR (1) BR9307734A (de)
CA (1) CA2152480A1 (de)
CZ (1) CZ165595A3 (de)
DE (2) DE69318727T2 (de)
ES (1) ES2077554T1 (de)
FI (1) FI953124A (de)
GR (1) GR950300061T1 (de)
HU (1) HUT72304A (de)
IL (1) IL108158A0 (de)
IS (1) IS4114A (de)
IT (1) IT1256248B (de)
MX (1) MX9400185A (de)
NO (1) NO952533L (de)
PL (1) PL309395A1 (de)
WO (1) WO1994014478A1 (de)
ZA (1) ZA939666B (de)

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IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5686061A (en) * 1994-04-11 1997-11-11 The Board Of Regents Of The University Of Texas System Particulate contrast media derived from non-ionic water soluble contrast agents for CT enhancement of hepatic tumors
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
GB9419206D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
US5575905A (en) * 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
AU6114396A (en) * 1995-06-16 1997-01-15 Biophysica Foundation Formyl derivatives as nonionic contrast media
DE59710863D1 (de) 1996-01-25 2003-11-20 Schering Ag Verbesserte kontrastmittenlösungen für die intravasale anwendung
DE19648650C2 (de) * 1996-01-29 1998-07-02 Schering Ag Puffersysteme und deren Verwendung zur Stabilisierung pharmazeutischer Zubereitung
DE19627309C2 (de) * 1996-06-27 1999-07-29 Schering Ag Wäßrige injizierbare Formulierungen verwendbar als Kontrastmittel
DE19736472C1 (de) * 1997-08-21 1999-04-22 Bernhard Dr Sixt Verfahren zum Herstellen von weitgehend nebenwirkungsfreien Kontrastmitteln
US6406680B1 (en) * 1999-09-17 2002-06-18 Nycomed Imaging As X-ray contrast agents
SE520688C2 (sv) 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
US6832220B1 (en) * 2000-08-03 2004-12-14 Microsoft Corporation Method and apparatus for file searching, accessing file identifiers from reference page
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
ES2289172T3 (es) 2001-12-20 2008-02-01 Bone Support Ab Un nuevo sustituto mineral de hueso.
GB0228410D0 (en) 2002-12-05 2003-01-08 Glaxo Group Ltd Novel Compounds
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
WO2005087272A2 (en) 2004-03-11 2005-09-22 Mallinckrodt Inc. X-ray contrast formulation comprising a mixture of iodinated monomer and dimer
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
US20100183522A1 (en) * 2007-06-29 2010-07-22 Lars-Goran Wistrand Contrast agents
AU2008273037B2 (en) * 2007-07-12 2012-11-15 Ge Healthcare As Contrast agents
CN101820923A (zh) * 2007-10-12 2010-09-01 通用电气医疗集团股份有限公司 对比剂
WO2009047316A1 (en) * 2007-10-12 2009-04-16 Ge Healthcare As Contrast agents
EP2231200A1 (de) * 2007-12-05 2010-09-29 GE Healthcare AS Kontrastmittel
EP2247314A4 (de) * 2008-02-01 2013-11-27 Univ Boston Kationische kontrastmittel und verfahren zu ihrer verwendung
EP2093206A1 (de) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Verfahren zur Iodierung aromatischer Verbindungen
EP2245003A2 (de) * 2008-02-27 2010-11-03 GE Healthcare AS Kontrastmittel
EP2245004A2 (de) * 2008-02-27 2010-11-03 GE Healthcare AS Kontrastmittel
WO2010060941A2 (en) * 2008-11-27 2010-06-03 Ge Healthcare As Contrast agents
EP2385845A1 (de) 2009-01-09 2011-11-16 Ge Healthcare As Kontrastmittel-zusammensetzungen
EP2230227A1 (de) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Verfahren zur Herstellung von aromatischen Trijodid-Carboxyl- Derivaten
EP2243767A1 (de) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Verfahren zur Iodierung aromatischer Verbindungen
US9157156B2 (en) 2009-07-07 2015-10-13 Bracco Imaging S.P.A. Process for the preparation of a iodinating agent
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
US10294107B2 (en) 2013-02-20 2019-05-21 Bone Support Ab Setting of hardenable bone substitute
JP6425375B2 (ja) * 2013-10-11 2018-11-21 新光電気工業株式会社 コイル基板及びその製造方法、インダクタ
WO2016123583A1 (en) 2015-01-29 2016-08-04 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
EP3548461B1 (de) 2016-12-05 2021-02-03 Bracco Imaging SpA Mechanochemische synthese von radiographischen mittelzwischenprodukten
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
WO2023209165A1 (en) 2022-04-29 2023-11-02 Bracco Imaging Spa Process for the preparation of 2,4,6-triiodophenol derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2613172A (en) * 1949-08-10 1952-10-07 American Cystoscope Makers Inc X-ray contrast compositions
CH608189A5 (de) * 1974-12-13 1978-12-29 Savac Ag
NL8002388A (nl) * 1979-05-21 1980-11-25 Mallinckrodt Inc Roentgencontrastmiddel.
FR2511871A1 (fr) * 1981-08-28 1983-03-04 Guerbet Sa Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus
GB8906130D0 (en) * 1989-03-17 1989-05-04 Nycomed As Compositions
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
US5191120A (en) * 1989-12-13 1993-03-02 Mallinckrodt Medical, Inc. Process for preparing nonionic X-ray contrast agents
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
WO1994005337A1 (en) * 1992-09-02 1994-03-17 Mallinckrodt Medical, Inc. Nonionic x-ray contrast agents, compositions and methods
US5260478A (en) * 1992-12-08 1993-11-09 Sterling Winthrop Inc. Iodinated aroyloxy carboxamides
NZ250063A (en) * 1992-12-14 1996-03-26 Eastman Kodak Co Iodinated aromatic acid ester derivatives; x-ray contrast compositions
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x

Also Published As

Publication number Publication date
ITMI922964A1 (it) 1994-06-24
JPH08505134A (ja) 1996-06-04
IS4114A (is) 1994-06-25
MX9400185A (es) 1994-07-29
NO952533D0 (no) 1995-06-23
HUT72304A (en) 1996-04-29
DE675738T1 (de) 1996-02-29
PL309395A1 (en) 1995-10-02
HU9501850D0 (en) 1995-08-28
BR9307734A (pt) 1999-08-31
IL108158A0 (en) 1994-04-12
EP0675738A1 (de) 1995-10-11
ES2077554T1 (es) 1995-12-01
US5695742A (en) 1997-12-09
CZ165595A3 (en) 1995-12-13
GR950300061T1 (en) 1995-11-30
DE69318727D1 (de) 1998-06-25
IT1256248B (it) 1995-11-29
WO1994014478A1 (en) 1994-07-07
NO952533L (no) 1995-08-16
CN1100329A (zh) 1995-03-22
FI953124A0 (fi) 1995-06-22
ATE166234T1 (de) 1998-06-15
FI953124A (fi) 1995-06-22
CA2152480A1 (en) 1994-07-07
ITMI922964A0 (it) 1992-12-24
AU5833294A (en) 1994-07-19
JP3585233B2 (ja) 2004-11-04
ZA939666B (en) 1994-08-29
EP0675738B1 (de) 1998-05-20

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