ES2076608T3 - Insuflador multi-dosis para medicamentos en forma de polvo. - Google Patents

Insuflador multi-dosis para medicamentos en forma de polvo.

Info

Publication number
ES2076608T3
ES2076608T3 ES92108490T ES92108490T ES2076608T3 ES 2076608 T3 ES2076608 T3 ES 2076608T3 ES 92108490 T ES92108490 T ES 92108490T ES 92108490 T ES92108490 T ES 92108490T ES 2076608 T3 ES2076608 T3 ES 2076608T3
Authority
ES
Spain
Prior art keywords
receptacle
deposit
powder
dose
hole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92108490T
Other languages
English (en)
Inventor
Salvatore Cocozza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Miat SpA
Original Assignee
Miat SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miat SpA filed Critical Miat SpA
Application granted granted Critical
Publication of ES2076608T3 publication Critical patent/ES2076608T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • B05B11/065—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time
    • B05B11/067—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time the particulate material being separated from the main storage by a dosing device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/10—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
    • G01F11/12—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements
    • G01F11/20—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates
    • G01F11/24—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates for fluent solid material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/075—Bulb type

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE PRESENTA UN INSUFLADOR MULTIDOSIS PARA LA ADMINISTRACION NASAL DE MEDICAMENTOS EN FORMA DE POLVO FINO O MICRONIZADO QUE COMPRENDE UN DEPOSITO (34), UNA UNIDAD (60, 64) PARA EXTRAER Y MEDIR EL MEDICAMENTO CONTENIDO EN EL DEPOSITO, Y UNA UNIDAD INSUFLADORA (42, 46) QUE COMPRENDE UNA BOMBA (42) QUE FUNCIONA MANUALMENTE PARA GENERAR UNA CORRIENTE DE AIRE EN EL INTERIOR DEL CANAL (26) PARA TRANSPORTAR UNA DOSIS INDIVIDUAL DE MEDICAMENTO AL INTERIOR DE LA CAVIDAD NASAL DEL PACIENTE. LA UNIDAD DE EXTRACCION Y MEDIDA COMPRENDE UN DISPOSITIVO TRANSPORTADOR (60) PROVISTO CON AL MENOS UN RECEPTACULO (64) PARA EXTRAER UNA DOSIS DEL MEDICAMENTO DEL DEPOSITO (34) Y TRANSPORTARLO HASTA LA POSICION DE INSUFLADO. EL RECEPTACULO (64) TIENE UN ORIFICIO COAXIAL EN SU BASE (66) A TRAVES DEL CUAL PASA LA CORRIENTE DE AIRE GENERADA POR LA BOMBA CUANDO EL RECEPTACULO SE ENCUENTRA EN LA POSICION DE INSUFLADO. EL ORIFICIO (66) TIENE UN TAMAÑO SUBSTANCIALMENTE MAS PEQUEÑO QUE LA BOCA DEL RECEPTACULO Y ESTO ES ASIPARA EVITAR QUE EL MEDICAMENTO EN POLVO CAIGA A TRAVES DEL ORIFICIO, EN VIRTUD DE UN EFECTO DE ARQUEAMIENTO.
ES92108490T 1991-06-14 1992-05-20 Insuflador multi-dosis para medicamentos en forma de polvo. Expired - Lifetime ES2076608T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911643A IT1248059B (it) 1991-06-14 1991-06-14 Insufflatore multidose per farmaci in polvere

Publications (1)

Publication Number Publication Date
ES2076608T3 true ES2076608T3 (es) 1995-11-01

Family

ID=11360122

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92108490T Expired - Lifetime ES2076608T3 (es) 1991-06-14 1992-05-20 Insuflador multi-dosis para medicamentos en forma de polvo.

Country Status (10)

Country Link
US (1) US5250287A (es)
EP (1) EP0518087B1 (es)
JP (1) JPH05200115A (es)
AT (1) ATE125161T1 (es)
CA (1) CA2070297C (es)
DE (1) DE69203541T2 (es)
DK (1) DK0518087T3 (es)
ES (1) ES2076608T3 (es)
GR (1) GR3017598T3 (es)
IT (1) IT1248059B (es)

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DE69233690T2 (de) * 1991-07-02 2008-01-24 Nektar Therapeutics, San Carlos Abgabevorrichtung für nebelförmige Medikamente
RU2111020C1 (ru) * 1992-12-18 1998-05-20 Шеринг Корпорейшн Ингалятор для порошковых лекарств
JP3132830B2 (ja) * 1993-05-12 2001-02-05 帝人株式会社 粉末状薬剤マルチドース施薬装置
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
DE4415462C1 (de) * 1994-05-03 1995-08-31 Transcoject Marketing Gmbh Inhalator
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
DE19518810A1 (de) * 1995-05-26 1996-11-28 Bayer Ag Nasal-Applikator
JP3434396B2 (ja) * 1995-06-30 2003-08-04 株式会社日立ユニシアオートモティブ 鼻腔用投薬器
IN188288B (es) * 1996-10-01 2002-08-31 Cipla Ltd
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US6076520A (en) * 1997-05-12 2000-06-20 Cooper; Emily L. Device for nasal therapeutic inhalation
US6345617B1 (en) 1997-09-26 2002-02-12 1263152 Ontario Inc. Aerosol medication delivery apparatus and system
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US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
JP3950738B2 (ja) * 2002-05-14 2007-08-01 株式会社 バイオアクティス 鼻腔用粉状薬剤施薬装置
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
CA2467975C (en) 2002-10-11 2010-12-21 Otsuka Pharmaceutical Co., Ltd. Powder inhalator
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US7654975B2 (en) * 2003-04-24 2010-02-02 Northgate Technologies, Inc. Mixed-gas insufflation system
FI20031158A (fi) * 2003-08-15 2005-02-16 Perlos Oyj Inhalaattori
US7704223B2 (en) * 2003-10-07 2010-04-27 Northgate Technologies Inc. System and method for delivering a substance to a body cavity
TWI288649B (en) * 2003-10-09 2007-10-21 Bioactis Ltd Powdery medicine dispensing device for nasal cavity
DE602004031034D1 (de) 2003-10-31 2011-02-24 Trudell Medical Int System zur manipulierung eines katheters für die ablage einer substanz in einer körperhöhle
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
DK1937219T3 (en) 2005-09-14 2016-02-15 Mannkind Corp A method for drug formulation based on increasing the affinity of the crystalline surfaces of the microparticle of active principles
US20090253654A1 (en) * 2005-09-22 2009-10-08 Galantos Pharma Gmbh Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
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IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
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IT1237118B (it) * 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.

Also Published As

Publication number Publication date
EP0518087A1 (en) 1992-12-16
GR3017598T3 (en) 1996-01-31
EP0518087B1 (en) 1995-07-19
IT1248059B (it) 1995-01-05
ITMI911643A0 (it) 1991-06-14
ITMI911643A1 (it) 1992-12-14
ATE125161T1 (de) 1995-08-15
US5250287A (en) 1993-10-05
DE69203541D1 (de) 1995-08-24
JPH05200115A (ja) 1993-08-10
DE69203541T2 (de) 1996-01-11
CA2070297C (en) 1999-01-26
CA2070297A1 (en) 1992-12-15
DK0518087T3 (da) 1995-11-27

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