ES2075887T3 - Procedimiento de preparacion de acido ascorbico. - Google Patents
Procedimiento de preparacion de acido ascorbico.Info
- Publication number
- ES2075887T3 ES2075887T3 ES90401592T ES90401592T ES2075887T3 ES 2075887 T3 ES2075887 T3 ES 2075887T3 ES 90401592 T ES90401592 T ES 90401592T ES 90401592 T ES90401592 T ES 90401592T ES 2075887 T3 ES2075887 T3 ES 2075887T3
- Authority
- ES
- Spain
- Prior art keywords
- ascorbic acid
- preparation procedure
- acid preparation
- sodium
- separation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ACIDO ASCORBICO PURO A PARTIR DE ACIDO CETO-2 L GULONICO O DE SU SAL DE SODIO, MEDIANTE LA REALIZACION DE LAS ETAPAS SUCESIVAS SIGUIENTES: ESTERIFICACION DEL ACIDO CETO-2 L GULONICO O DE SU SAL DE SODIO; LACTONIZACION EN ASCORBATO DE SODIO; SEPARACION EVENTUAL DEL ASCORBATO DE SODIO; DESPLAZAMIENTO DEL ACIDO ASCORBICO DE SU SAL; SEPARACION DEL SULFATO DE SODIO; SEPARACION Y PURIFICACION DEL ACIDO ASCORBICO A PARTIR DE SU DISOLUCION METANOLICA O HIDROMETANOLICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR898907716A FR2648136B1 (fr) | 1989-06-12 | 1989-06-12 | Procede de preparation de l'acide ascorbique |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2075887T3 true ES2075887T3 (es) | 1995-10-16 |
ES2075887T5 ES2075887T5 (es) | 2000-12-16 |
Family
ID=9382598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90401592T Expired - Lifetime ES2075887T5 (es) | 1989-06-12 | 1990-06-11 | Procedimiento de preparacion de acido ascorbico. |
Country Status (16)
Country | Link |
---|---|
US (1) | US5391770A (es) |
EP (1) | EP0403351B2 (es) |
JP (1) | JP2921927B2 (es) |
KR (1) | KR100210636B1 (es) |
AT (1) | ATE126223T1 (es) |
CA (1) | CA2018692C (es) |
DE (1) | DE69021455T3 (es) |
DK (1) | DK0403351T4 (es) |
ES (1) | ES2075887T5 (es) |
FR (1) | FR2648136B1 (es) |
GR (2) | GR3017085T3 (es) |
HU (1) | HU205754B (es) |
IE (1) | IE69381B1 (es) |
PT (1) | PT94354B (es) |
RU (1) | RU1833383C (es) |
YU (1) | YU48323B (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1036457C (zh) * | 1991-10-01 | 1997-11-19 | 武田药品工业株式会社 | 2-酮基-l-古洛糖酸低级烷基脂的制备方法 |
EP0671405A1 (de) * | 1994-01-18 | 1995-09-13 | F. Hoffmann-La Roche Ag | Herstellung von 2-Keto-L-gulonsäureestern |
JPH08176133A (ja) * | 1994-12-26 | 1996-07-09 | Takeda Chem Ind Ltd | L−アスコルビン酸の精製法 |
IL115564A (en) * | 1995-10-11 | 1999-06-20 | Yissum Res Dev Co | Process for the recovery of ascorbic acid from an aqueous feed solution |
DE19547073C1 (de) * | 1995-12-16 | 1996-11-14 | Merck Patent Gmbh | Verfahren zur Herstellung von Ascorbinsäure |
JP3976832B2 (ja) * | 1996-04-30 | 2007-09-19 | ディーエスエム アイピー アセッツ ビー.ブイ. | 2−ケト−l−グロン酸の単離方法 |
IL119731A0 (en) * | 1996-12-01 | 1997-03-18 | Yissum Res Dev Co | A process for the production of erythorbic acid |
US5998634A (en) * | 1999-03-15 | 1999-12-07 | The United States Of America As Represented By The Secretary Of The Interior | One-step synthesis of vitamin-C (L-ascorbic acid) |
DE19919203A1 (de) | 1999-04-28 | 2000-11-02 | Basf Ag | Verfahren zur Herstellung von L-Ascorbinsäure |
US6153791A (en) * | 1999-08-02 | 2000-11-28 | Archer-Daniels-Midland Company | Process for purifying 2-keto-L-gulonic acid |
US6902917B1 (en) * | 1999-08-03 | 2005-06-07 | Archer-Daniels-Midland Company | Process for recovery of organic acids from fermentration broths |
DE19938980A1 (de) * | 1999-08-19 | 2001-02-22 | Basf Ag | Verfahren zur Herstellung von 2-Keto-L-gulonsäureestern |
DE19954511A1 (de) * | 1999-11-12 | 2001-05-17 | Basf Ag | Verfahren zur Herstellung von Alkalisalzen der L-Ascorbinsäure |
US6670505B1 (en) | 2000-03-07 | 2003-12-30 | Eastman Chemical Company | Process for the recovery of organic acids from aqueous solutions |
DE10022518A1 (de) | 2000-05-10 | 2001-11-15 | Basf Ag | Verfahren zur Herstellung von L-Ascorbinsäure durch Lactonisierung von 2-Keto-L-gulonsäure oder 2-Keto-L-gulonsäureestern |
US6320061B1 (en) | 2000-06-05 | 2001-11-20 | Eastman Chemical Company | Solvent exchange process |
DE60113158T2 (de) * | 2000-12-22 | 2006-06-08 | Eastman Chemical Co., Kingsport | Verfahren zur herstellung von ascorbinsäure in gegenwart eines sulfits |
BR0116451A (pt) | 2000-12-22 | 2003-09-30 | Eastman Chem Co | Processo contìnuo para manufatura de ácido l-ascórbico |
US6740762B2 (en) | 2001-08-24 | 2004-05-25 | Eastman Chemical Company | Process for ascorbic acids using alkaline earth silicate catalysts |
US6716997B1 (en) | 2001-10-09 | 2004-04-06 | Eastman Chemical Company | Systems and methods for generation of ascorbic acid with reduced color |
WO2003031427A1 (en) * | 2001-10-09 | 2003-04-17 | Eastman Chemical Company | Systems and methods for generation of ascorbic acid with reduced color |
DE10149869A1 (de) * | 2001-10-10 | 2003-04-24 | Basf Ag | Verfahren zur Isolierung von Salzen von organischen Säuren aus einer Fermentationsbrühe und zur Freisetzung der organischen Säure |
US6518454B1 (en) | 2001-10-12 | 2003-02-11 | Eastman Chemical Company | Preparation of esters of carboxylic acids |
US6476239B1 (en) | 2002-02-12 | 2002-11-05 | Eastman Chemical Company | Process for the preparation of ascorbic acid |
JP2006505607A (ja) * | 2002-11-11 | 2006-02-16 | ビーエーエスエフ アクチェンゲゼルシャフト | 2−ケト−l−グロン酸c4−c10−アルキルエステルを調製するための方法 |
US6872314B2 (en) * | 2003-08-29 | 2005-03-29 | Eastman Chemical Company | Dewatering process |
US7799942B2 (en) * | 2005-08-12 | 2010-09-21 | Eastman Chemical Company | Production of terephthalic acid di-esters |
US7276621B2 (en) * | 2005-08-12 | 2007-10-02 | Eastman Chemical Company | Production of di-(2-ethylhexyl) terephthalate |
US7741509B2 (en) * | 2007-01-30 | 2010-06-22 | Eastman Chemical Company | Conversion of terephthalic acid to Di-n-butyl terephthalate |
CN100545156C (zh) * | 2007-04-10 | 2009-09-30 | 三达膜科技(厦门)有限公司 | 维生素c母液中回收维生素c和古龙酸的生产方法 |
CN101914079B (zh) * | 2010-08-20 | 2012-06-06 | 安徽丰原发酵技术工程研究有限公司 | 一种维生素c的生产方法 |
CN102424695A (zh) * | 2011-10-28 | 2012-04-25 | 安徽泰格生物技术股份有限公司 | 一种古龙酸甲酯钠及其制备方法 |
CN111018814B (zh) * | 2019-12-06 | 2022-11-08 | 石药集团维生药业(石家庄)有限公司 | 一种维生素c二母液回收利用的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2265121A (en) * | 1933-10-25 | 1941-12-02 | Hoffmann La Roche | Process for the manufacture of levoascorbic acid |
FR779883A (fr) * | 1933-10-25 | 1935-04-13 | Hoffmann La Roche | Procédé de préparation de l'acide 1-ascorbique |
US2443583A (en) * | 1944-07-12 | 1948-06-15 | Hugh H Mottern | Manufacture of ascorbic acid |
FR922949A (fr) * | 1946-02-26 | 1947-06-23 | Bataafsche Petroleum | Procédé pour préparer l'acide ascorbique à partir d'esters de l'acide cetogulonique |
JPS6019285B2 (ja) * | 1977-02-07 | 1985-05-15 | 武田薬品工業株式会社 | 分別方法 |
PL130761B1 (en) * | 1980-07-18 | 1984-09-29 | Krakowskie Zaklady Pharma | Process for preparing 1-ascorbic acid from its salts |
JPS58177986A (ja) * | 1982-04-09 | 1983-10-18 | Shionogi & Co Ltd | L−アスコルビン酸の製造方法 |
JP3433820B2 (ja) * | 1993-05-07 | 2003-08-04 | 関西電力株式会社 | ガス燃焼装置及びガス燃焼システム |
-
1989
- 1989-06-12 FR FR898907716A patent/FR2648136B1/fr not_active Expired - Lifetime
-
1990
- 1990-06-08 RU SU904830021A patent/RU1833383C/ru active
- 1990-06-11 DE DE69021455T patent/DE69021455T3/de not_active Expired - Lifetime
- 1990-06-11 EP EP90401592A patent/EP0403351B2/fr not_active Expired - Lifetime
- 1990-06-11 DK DK90401592T patent/DK0403351T4/da active
- 1990-06-11 JP JP2150081A patent/JP2921927B2/ja not_active Expired - Lifetime
- 1990-06-11 ES ES90401592T patent/ES2075887T5/es not_active Expired - Lifetime
- 1990-06-11 AT AT90401592T patent/ATE126223T1/de not_active IP Right Cessation
- 1990-06-11 IE IE209590A patent/IE69381B1/en not_active IP Right Cessation
- 1990-06-11 HU HU903799A patent/HU205754B/hu unknown
- 1990-06-11 CA CA002018692A patent/CA2018692C/fr not_active Expired - Lifetime
- 1990-06-11 KR KR1019900008530A patent/KR100210636B1/ko not_active IP Right Cessation
- 1990-06-11 YU YU113690A patent/YU48323B/sh unknown
- 1990-06-12 PT PT94354A patent/PT94354B/pt not_active IP Right Cessation
-
1993
- 1993-12-23 US US08/171,988 patent/US5391770A/en not_active Expired - Lifetime
-
1995
- 1995-08-10 GR GR950400344T patent/GR3017085T3/el unknown
-
2000
- 2000-08-03 GR GR20000401816T patent/GR3034121T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR100210636B1 (ko) | 1999-07-15 |
GR3034121T3 (en) | 2000-11-30 |
KR910000692A (ko) | 1991-01-30 |
HUT54131A (en) | 1991-01-28 |
HU205754B (en) | 1992-06-29 |
DE69021455D1 (de) | 1995-09-14 |
RU1833383C (ru) | 1993-08-07 |
IE69381B1 (en) | 1996-09-04 |
GR3017085T3 (en) | 1995-11-30 |
DE69021455T2 (de) | 1996-02-01 |
DK0403351T4 (da) | 2000-09-25 |
DK0403351T3 (da) | 1995-09-18 |
PT94354A (pt) | 1991-02-08 |
PT94354B (pt) | 2001-06-29 |
US5391770A (en) | 1995-02-21 |
JP2921927B2 (ja) | 1999-07-19 |
JPH0324068A (ja) | 1991-02-01 |
YU48323B (sh) | 1998-05-15 |
DE69021455T3 (de) | 2001-02-22 |
EP0403351B2 (fr) | 2000-08-23 |
ES2075887T5 (es) | 2000-12-16 |
IE902095L (en) | 1990-12-12 |
ATE126223T1 (de) | 1995-08-15 |
EP0403351A1 (fr) | 1990-12-19 |
YU113690A (sh) | 1992-09-07 |
FR2648136A1 (fr) | 1990-12-14 |
FR2648136B1 (fr) | 1994-06-17 |
EP0403351B1 (fr) | 1995-08-09 |
CA2018692A1 (fr) | 1990-12-12 |
HU903799D0 (en) | 1990-11-28 |
CA2018692C (fr) | 2001-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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