ES2075135T3 - Sensor con antigeno quimicamente enlazado a un dispositivo semiconductor. - Google Patents

Sensor con antigeno quimicamente enlazado a un dispositivo semiconductor.

Info

Publication number
ES2075135T3
ES2075135T3 ES90200915T ES90200915T ES2075135T3 ES 2075135 T3 ES2075135 T3 ES 2075135T3 ES 90200915 T ES90200915 T ES 90200915T ES 90200915 T ES90200915 T ES 90200915T ES 2075135 T3 ES2075135 T3 ES 2075135T3
Authority
ES
Spain
Prior art keywords
sensor
membrane
chemically linked
semiconductive device
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90200915T
Other languages
English (en)
Inventor
Claudio Colapicchioni
Filippo Porcelli
Carlo Antonio Nuzzolo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eni Tecnologie SpA
Original Assignee
Eniricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche SpA filed Critical Eniricerche SpA
Application granted granted Critical
Publication of ES2075135T3 publication Critical patent/ES2075135T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

SE OFRECE UNA DESCRIPCION, JUNTO CON PROCESOS DE PREPARACION RELATIVA, DE UN SENSOR QUE CONTIENE UNA MEMBRANA INMUNOQUIMICA Y UN DISPOSITIVO DEL TIPO EOS O CHEMFET, QUE CONTIENE OXIDO DE SILICE DE SUPERFICIE, QUE SE ADHIERE A DICHA MEMBRANA A TRAVES DE UNA MATRIZ DE POLISILOXANO, CARACTERIZADA EN QUE LA MEMBRANA INMUNOQUIMICA ESTA FORMADA DE UN ANTIGENO FUNCIONALIZADO O DEL MISMO ANTIGENO FUNCIONALIZADO LIGADO A UNA PROTEINA, ESTANDO LIGADA QUIMICAMENTE DICHA MEMBRANA INMUNOQUIMICA A LA MATRIZ DE POLISILOXANO MEDIANTE GRUPOS FUNCIONALES PRESENTES SOBRE EL MISMO ANTIGENO O MEDIANTE AGENTES DE ACOPLAMIENTO BIFUNCIONALES.
ES90200915T 1989-04-21 1990-04-13 Sensor con antigeno quimicamente enlazado a un dispositivo semiconductor. Expired - Lifetime ES2075135T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920259A IT1229691B (it) 1989-04-21 1989-04-21 Sensore con antigene legato chimicamente a un dispositivo semiconduttore.

Publications (1)

Publication Number Publication Date
ES2075135T3 true ES2075135T3 (es) 1995-10-01

Family

ID=11165221

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90200915T Expired - Lifetime ES2075135T3 (es) 1989-04-21 1990-04-13 Sensor con antigeno quimicamente enlazado a un dispositivo semiconductor.

Country Status (9)

Country Link
US (1) US5160597A (es)
EP (1) EP0395137B1 (es)
JP (1) JPH02296142A (es)
AT (1) ATE126597T1 (es)
DE (1) DE69021621T2 (es)
DK (1) DK0395137T3 (es)
ES (1) ES2075135T3 (es)
GR (1) GR3017224T3 (es)
IT (1) IT1229691B (es)

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WO1993019374A1 (en) * 1992-03-16 1993-09-30 Immuna Care Corporation Improved test kit for the determination of steroids and related compounds
CA2108705A1 (en) * 1992-11-06 1994-05-07 Richard Barner Biologically recognizing layers on new ti02 waveguide for biosensors
FR2722294B1 (fr) * 1994-07-07 1996-10-04 Lyon Ecole Centrale Procede d'analyse qualitative et/ou quantitative de substances biologiques presentes dans un milieu liquide conducteur et capteurs biochimiques d'affinite utilises pour la mise en oeuvre de ce procede
US7468398B2 (en) 1994-09-06 2008-12-23 Ciba Vision Corporation Extended wear ophthalmic lens
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US6355436B1 (en) 1996-05-17 2002-03-12 L'ecole Centrale De Lyon Method for analyzing biological substances in a conductive liquid medium
SE9602545L (sv) 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
US6699667B2 (en) 1997-05-14 2004-03-02 Keensense, Inc. Molecular wire injection sensors
US6060327A (en) * 1997-05-14 2000-05-09 Keensense, Inc. Molecular wire injection sensors
WO1999040434A1 (en) 1998-02-04 1999-08-12 Invitrogen Corporation Microarrays and uses therefor
US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US6576478B1 (en) 1998-07-14 2003-06-10 Zyomyx, Inc. Microdevices for high-throughput screening of biomolecules
US6682942B1 (en) 1998-07-14 2004-01-27 Zyomyx, Inc. Microdevices for screening biomolecules
US6897073B2 (en) 1998-07-14 2005-05-24 Zyomyx, Inc. Non-specific binding resistant protein arrays and methods for making the same
US20020119579A1 (en) * 1998-07-14 2002-08-29 Peter Wagner Arrays devices and methods of use thereof
US7439056B2 (en) 2000-11-08 2008-10-21 Surface Logix Inc. Peelable and resealable devices for arraying materials
US7371563B2 (en) * 2000-11-08 2008-05-13 Surface Logix, Inc. Peelable and resealable devices for biochemical assays
US6967074B2 (en) * 2000-11-08 2005-11-22 Surface Logix, Inc. Methods of detecting immobilized biomolecules
US7001740B2 (en) * 2000-11-08 2006-02-21 Surface Logix, Inc. Methods of arraying biological materials using peelable and resealable devices
US7351575B2 (en) * 2000-11-08 2008-04-01 Surface Logix, Inc. Methods for processing biological materials using peelable and resealable devices
US6803205B2 (en) * 2000-11-08 2004-10-12 Surface Logix, Inc. Methods of measuring enzyme activity using peelable and resealable devices
GB0105831D0 (en) * 2001-03-09 2001-04-25 Toumaz Technology Ltd Method for dna sequencing utilising enzyme linked field effect transistors
US20050053949A1 (en) * 2003-09-08 2005-03-10 Silin Vitalii Ivanovich Biochip for proteomics applications
US7318887B2 (en) * 2003-10-08 2008-01-15 Honeywell International Inc. Solid state reference electrode
US8198658B2 (en) * 2007-06-13 2012-06-12 Samsung Electronics Co., Ltd. Device and method for detecting biomolecules using adsorptive medium and field effect transistor
KR101465961B1 (ko) * 2007-10-09 2014-12-01 삼성전자주식회사 유전자 검출 방법 및 장치
US9029132B2 (en) 2009-08-06 2015-05-12 International Business Machines Corporation Sensor for biomolecules
US8052931B2 (en) 2010-01-04 2011-11-08 International Business Machines Corporation Ultra low-power CMOS based bio-sensor circuit
US9068935B2 (en) 2010-04-08 2015-06-30 International Business Machines Corporation Dual FET sensor for sensing biomolecules and charged ions in an electrolyte
EP2469275B1 (en) 2010-12-24 2015-12-23 Honeywell Romania S.R.L. Cantilevered carbon dioxide sensor
WO2013112541A2 (en) 2012-01-23 2013-08-01 The Ohio State University Devices and methods for the rapid and accurate detection of analytes
JP6167114B2 (ja) * 2012-01-31 2017-07-19 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ ナノ構造の酸化銀膜使用の水性ボルタンメトリー農薬センサおよびそのセンサの製造方法
US20230236147A1 (en) * 2020-05-27 2023-07-27 Jose Maria Piccinini Sensors and systems based on field-effect transistors, methods of preparation and devices for their operation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5825221B2 (ja) * 1977-12-12 1983-05-26 株式会社クラレ Ｆｅｔ比較電極
GB8314523D0 (en) * 1983-05-25 1983-06-29 Lowe C R Diagnostic device
GB8406955D0 (en) * 1984-03-16 1984-04-18 Serono Diagnostics Ltd Assay
US4708947A (en) * 1985-01-10 1987-11-24 Kuraray Co., Ltd. Water resistant composition and heat-sensitive recording sheet containing the same
JPH0721478B2 (ja) * 1986-03-31 1995-03-08 財団法人化学及血清療法研究所 免疫センサ−用作用膜
IT1215491B (it) * 1987-05-15 1990-02-14 Enricerche Spa Biosensore con membrana enzimatica legata chimicamente a un dispositivo semiconduttore.
US5001048A (en) * 1987-06-05 1991-03-19 Aurthur D. Little, Inc. Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film

Also Published As

Publication number Publication date
US5160597A (en) 1992-11-03
DE69021621D1 (de) 1995-09-21
EP0395137A2 (en) 1990-10-31
ATE126597T1 (de) 1995-09-15
IT8920259A0 (it) 1989-04-21
EP0395137B1 (en) 1995-08-16
DE69021621T2 (de) 1996-03-14
GR3017224T3 (en) 1995-11-30
JPH02296142A (ja) 1990-12-06
DK0395137T3 (da) 1995-11-06
IT1229691B (it) 1991-09-06
EP0395137A3 (en) 1991-06-12

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