DE69021621T2 - Sensor mit einem Antigen, das chemisch an eine Halbleitervorrichtung gebunden ist. - Google Patents

Sensor mit einem Antigen, das chemisch an eine Halbleitervorrichtung gebunden ist.

Info

Publication number
DE69021621T2
DE69021621T2 DE69021621T DE69021621T DE69021621T2 DE 69021621 T2 DE69021621 T2 DE 69021621T2 DE 69021621 T DE69021621 T DE 69021621T DE 69021621 T DE69021621 T DE 69021621T DE 69021621 T2 DE69021621 T2 DE 69021621T2
Authority
DE
Germany
Prior art keywords
antigen
membrane
sensor
semiconductor device
chemically bound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69021621T
Other languages
English (en)
Other versions
DE69021621D1 (de
Inventor
Claudio Colapicchioni
Filippo Porcelli
Carlo Antonio Nuzzolo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eni Tecnologie SpA
Original Assignee
Eniricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche SpA filed Critical Eniricerche SpA
Publication of DE69021621D1 publication Critical patent/DE69021621D1/de
Application granted granted Critical
Publication of DE69021621T2 publication Critical patent/DE69021621T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69021621T 1989-04-21 1990-04-13 Sensor mit einem Antigen, das chemisch an eine Halbleitervorrichtung gebunden ist. Expired - Fee Related DE69021621T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920259A IT1229691B (it) 1989-04-21 1989-04-21 Sensore con antigene legato chimicamente a un dispositivo semiconduttore.

Publications (2)

Publication Number Publication Date
DE69021621D1 DE69021621D1 (de) 1995-09-21
DE69021621T2 true DE69021621T2 (de) 1996-03-14

Family

ID=11165221

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69021621T Expired - Fee Related DE69021621T2 (de) 1989-04-21 1990-04-13 Sensor mit einem Antigen, das chemisch an eine Halbleitervorrichtung gebunden ist.

Country Status (9)

Country Link
US (1) US5160597A (de)
EP (1) EP0395137B1 (de)
JP (1) JPH02296142A (de)
AT (1) ATE126597T1 (de)
DE (1) DE69021621T2 (de)
DK (1) DK0395137T3 (de)
ES (1) ES2075135T3 (de)
GR (1) GR3017224T3 (de)
IT (1) IT1229691B (de)

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WO1993019374A1 (en) * 1992-03-16 1993-09-30 Immuna Care Corporation Improved test kit for the determination of steroids and related compounds
CA2108705A1 (en) * 1992-11-06 1994-05-07 Richard Barner Biologically recognizing layers on new ti02 waveguide for biosensors
FR2722294B1 (fr) * 1994-07-07 1996-10-04 Lyon Ecole Centrale Procede d'analyse qualitative et/ou quantitative de substances biologiques presentes dans un milieu liquide conducteur et capteurs biochimiques d'affinite utilises pour la mise en oeuvre de ce procede
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US7468398B2 (en) 1994-09-06 2008-12-23 Ciba Vision Corporation Extended wear ophthalmic lens
US6355436B1 (en) 1996-05-17 2002-03-12 L'ecole Centrale De Lyon Method for analyzing biological substances in a conductive liquid medium
SE9602545L (sv) * 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
US6060327A (en) * 1997-05-14 2000-05-09 Keensense, Inc. Molecular wire injection sensors
US6699667B2 (en) 1997-05-14 2004-03-02 Keensense, Inc. Molecular wire injection sensors
JP2002502977A (ja) 1998-02-04 2002-01-29 インビトロジェン コーポレイション マイクロアレイとその使用
US6897073B2 (en) 1998-07-14 2005-05-24 Zyomyx, Inc. Non-specific binding resistant protein arrays and methods for making the same
US6576478B1 (en) 1998-07-14 2003-06-10 Zyomyx, Inc. Microdevices for high-throughput screening of biomolecules
US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US20020119579A1 (en) * 1998-07-14 2002-08-29 Peter Wagner Arrays devices and methods of use thereof
US6682942B1 (en) 1998-07-14 2004-01-27 Zyomyx, Inc. Microdevices for screening biomolecules
US7001740B2 (en) * 2000-11-08 2006-02-21 Surface Logix, Inc. Methods of arraying biological materials using peelable and resealable devices
US7371563B2 (en) * 2000-11-08 2008-05-13 Surface Logix, Inc. Peelable and resealable devices for biochemical assays
US7351575B2 (en) * 2000-11-08 2008-04-01 Surface Logix, Inc. Methods for processing biological materials using peelable and resealable devices
US6803205B2 (en) * 2000-11-08 2004-10-12 Surface Logix, Inc. Methods of measuring enzyme activity using peelable and resealable devices
US7439056B2 (en) 2000-11-08 2008-10-21 Surface Logix Inc. Peelable and resealable devices for arraying materials
US6967074B2 (en) * 2000-11-08 2005-11-22 Surface Logix, Inc. Methods of detecting immobilized biomolecules
GB0105831D0 (en) * 2001-03-09 2001-04-25 Toumaz Technology Ltd Method for dna sequencing utilising enzyme linked field effect transistors
US20050053949A1 (en) * 2003-09-08 2005-03-10 Silin Vitalii Ivanovich Biochip for proteomics applications
US7318887B2 (en) * 2003-10-08 2008-01-15 Honeywell International Inc. Solid state reference electrode
US8198658B2 (en) * 2007-06-13 2012-06-12 Samsung Electronics Co., Ltd. Device and method for detecting biomolecules using adsorptive medium and field effect transistor
KR101465961B1 (ko) * 2007-10-09 2014-12-01 삼성전자주식회사 유전자 검출 방법 및 장치
US9029132B2 (en) * 2009-08-06 2015-05-12 International Business Machines Corporation Sensor for biomolecules
US8052931B2 (en) 2010-01-04 2011-11-08 International Business Machines Corporation Ultra low-power CMOS based bio-sensor circuit
US9068935B2 (en) 2010-04-08 2015-06-30 International Business Machines Corporation Dual FET sensor for sensing biomolecules and charged ions in an electrolyte
EP2469275B1 (de) 2010-12-24 2015-12-23 Honeywell Romania S.R.L. Cantilever-Kohlendioxidsensor
WO2013112541A2 (en) 2012-01-23 2013-08-01 The Ohio State University Devices and methods for the rapid and accurate detection of analytes
JP6167114B2 (ja) * 2012-01-31 2017-07-19 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ ナノ構造の酸化銀膜使用の水性ボルタンメトリー農薬センサおよびそのセンサの製造方法
AR122169A1 (es) * 2020-05-27 2022-08-24 Gisens Biotech S A Sensores y sistemas basados en transistores de efecto de campo, métodos de preparación y dispositivos para su operación

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5825221B2 (ja) * 1977-12-12 1983-05-26 株式会社クラレ Ｆｅｔ比較電極
GB8314523D0 (en) * 1983-05-25 1983-06-29 Lowe C R Diagnostic device
GB8406955D0 (en) * 1984-03-16 1984-04-18 Serono Diagnostics Ltd Assay
US4708947A (en) * 1985-01-10 1987-11-24 Kuraray Co., Ltd. Water resistant composition and heat-sensitive recording sheet containing the same
JPH0721478B2 (ja) * 1986-03-31 1995-03-08 財団法人化学及血清療法研究所 免疫センサ−用作用膜
IT1215491B (it) * 1987-05-15 1990-02-14 Enricerche Spa Biosensore con membrana enzimatica legata chimicamente a un dispositivo semiconduttore.
US5001048A (en) * 1987-06-05 1991-03-19 Aurthur D. Little, Inc. Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film

Also Published As

Publication number Publication date
IT1229691B (it) 1991-09-06
EP0395137B1 (de) 1995-08-16
US5160597A (en) 1992-11-03
GR3017224T3 (en) 1995-11-30
ES2075135T3 (es) 1995-10-01
DK0395137T3 (da) 1995-11-06
DE69021621D1 (de) 1995-09-21
JPH02296142A (ja) 1990-12-06
ATE126597T1 (de) 1995-09-15
IT8920259A0 (it) 1989-04-21
EP0395137A3 (de) 1991-06-12
EP0395137A2 (de) 1990-10-31

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee