ES2075061T3 - Composicion farmaceutica a base de una resina de intercambio ionico. - Google Patents

Composicion farmaceutica a base de una resina de intercambio ionico.

Info

Publication number
ES2075061T3
ES2075061T3 ES89311701T ES89311701T ES2075061T3 ES 2075061 T3 ES2075061 T3 ES 2075061T3 ES 89311701 T ES89311701 T ES 89311701T ES 89311701 T ES89311701 T ES 89311701T ES 2075061 T3 ES2075061 T3 ES 2075061T3
Authority
ES
Spain
Prior art keywords
ion exchange
exchange resin
pharmaceutical composition
alcohol
composition based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89311701T
Other languages
English (en)
Inventor
Sandra Therese Antoi Malkowska
Ian Richard Buxton
Derek Allan Prater
Alison Anne Norman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888826407A external-priority patent/GB8826407D0/en
Priority claimed from GB888828592A external-priority patent/GB8828592D0/en
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of ES2075061T3 publication Critical patent/ES2075061T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA DE RESINA INTERCAMBIANDO IONES QUE ES FACILMENTE DISPERSABLE EN AGUA COMPRENDIENDO GRANULAR UNA RESINA INTERCAMBIADORA DE IONES, TENIENDO UN INGREDIENTE ACTIVO FARMACOLOGICAMENTE UNIDO A ELLA, CON UN AZUCAR O UN ALCOHOL AZUCARADO EN PRESENCIA DE AGUA SUFICIENTE, ALCOHOL ACUOSO O ALCOHOL QUE PERMITA LA GRANULACION. PREFERIBLEMENTE EL INGREDIENTE ACTIVO ES MORFINA O METOCLOPRAMINA Y EL ALCOHOL AZUCARADO ES SILITOL. LA GRANULACION MEJOR QUE LA PURA MEZCLA, MEJORA EL MARGEN EN EL CUAL LA COMPOSICION FORMA UNA SUSPENSION EN AGUA.
ES89311701T 1988-11-11 1989-11-10 Composicion farmaceutica a base de una resina de intercambio ionico. Expired - Lifetime ES2075061T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888826407A GB8826407D0 (en) 1988-11-11 1988-11-11 Pharmaceutical ion exchange resin composition
GB888828592A GB8828592D0 (en) 1988-12-07 1988-12-07 Pharmaceutical ion exchange resin composition

Publications (1)

Publication Number Publication Date
ES2075061T3 true ES2075061T3 (es) 1995-10-01

Family

ID=26294609

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89311701T Expired - Lifetime ES2075061T3 (es) 1988-11-11 1989-11-10 Composicion farmaceutica a base de una resina de intercambio ionico.

Country Status (11)

Country Link
US (1) US5071646A (es)
EP (1) EP0368682B1 (es)
JP (1) JP2825202B2 (es)
AT (1) ATE123218T1 (es)
AU (1) AU621949B2 (es)
CA (1) CA2002492A1 (es)
DE (1) DE68922894T2 (es)
DK (1) DK175154B1 (es)
ES (1) ES2075061T3 (es)
GB (1) GB2225941B (es)
IE (1) IE893625L (es)

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Also Published As

Publication number Publication date
JP2825202B2 (ja) 1998-11-18
DE68922894T2 (de) 1996-01-11
DE68922894D1 (de) 1995-07-06
AU621949B2 (en) 1992-03-26
ATE123218T1 (de) 1995-06-15
US5071646A (en) 1991-12-10
IE893625L (en) 1990-05-11
DK564589D0 (da) 1989-11-10
EP0368682A1 (en) 1990-05-16
AU4453089A (en) 1990-05-17
EP0368682B1 (en) 1995-05-31
GB2225941B (en) 1992-12-09
CA2002492A1 (en) 1990-05-11
JPH02243618A (ja) 1990-09-27
GB2225941A (en) 1990-06-20
DK564589A (da) 1990-05-12
DK175154B1 (da) 2004-06-21
GB8925492D0 (en) 1989-12-28

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