DK564589A - Farmaceutisk ionbytterharpikssammensaetning - Google Patents

Farmaceutisk ionbytterharpikssammensaetning

Info

Publication number
DK564589A
DK564589A DK564589A DK564589A DK564589A DK 564589 A DK564589 A DK 564589A DK 564589 A DK564589 A DK 564589A DK 564589 A DK564589 A DK 564589A DK 564589 A DK564589 A DK 564589A
Authority
DK
Denmark
Prior art keywords
ion exchange
exchange resin
resin composition
alcohol
water
Prior art date
Application number
DK564589A
Other languages
English (en)
Other versions
DK564589D0 (da
DK175154B1 (da
Inventor
Sandra Theresa Antio Malkowska
Ian Richard Buxton
Derek Allan Prater
Alison Anne Norman
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888826407A external-priority patent/GB8826407D0/en
Priority claimed from GB888828592A external-priority patent/GB8828592D0/en
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of DK564589D0 publication Critical patent/DK564589D0/da
Publication of DK564589A publication Critical patent/DK564589A/da
Application granted granted Critical
Publication of DK175154B1 publication Critical patent/DK175154B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
DK198905645A 1988-11-11 1989-11-10 Fremgangsmåde til fremstilling af en farmaceutisk ionbytterharpikssammensætning DK175154B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8826407 1988-11-11
GB888826407A GB8826407D0 (en) 1988-11-11 1988-11-11 Pharmaceutical ion exchange resin composition
GB8828592 1988-12-07
GB888828592A GB8828592D0 (en) 1988-12-07 1988-12-07 Pharmaceutical ion exchange resin composition

Publications (3)

Publication Number Publication Date
DK564589D0 DK564589D0 (da) 1989-11-10
DK564589A true DK564589A (da) 1990-05-12
DK175154B1 DK175154B1 (da) 2004-06-21

Family

ID=26294609

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198905645A DK175154B1 (da) 1988-11-11 1989-11-10 Fremgangsmåde til fremstilling af en farmaceutisk ionbytterharpikssammensætning

Country Status (11)

Country Link
US (1) US5071646A (da)
EP (1) EP0368682B1 (da)
JP (1) JP2825202B2 (da)
AT (1) ATE123218T1 (da)
AU (1) AU621949B2 (da)
CA (1) CA2002492A1 (da)
DE (1) DE68922894T2 (da)
DK (1) DK175154B1 (da)
ES (1) ES2075061T3 (da)
GB (1) GB2225941B (da)
IE (1) IE893625L (da)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9003903D0 (sv) * 1990-12-07 1990-12-07 Astra Ab New pharmaceutical formulations
SE9003904D0 (sv) * 1990-12-07 1990-12-07 Astra Ab Method for the manufacture of a pharmaceutical dosage form
US5275820A (en) * 1990-12-27 1994-01-04 Allergan, Inc. Stable suspension formulations of bioerodible polymer matrix microparticles incorporating drug loaded ion exchange resin particles
US5840339A (en) * 1991-07-30 1998-11-24 Kunin; Robert Blood cholesterol reducing pharmaceutical composition
SE9103110D0 (sv) * 1991-10-24 1991-10-24 Kabi Pharmacia Ab New drug formulation
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US5296228A (en) * 1992-03-13 1994-03-22 Allergan, Inc. Compositions for controlled delivery of pharmaceutical compounds
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
IL119660A (en) * 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) * 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5931809A (en) 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
GB9517883D0 (en) * 1995-09-01 1995-11-01 Euro Celtique Sa Improved pharmaceutical ion exchange resin composition
GB9519363D0 (en) 1995-09-22 1995-11-22 Euro Celtique Sa Pharmaceutical formulation
WO1998036737A1 (en) * 1997-02-25 1998-08-27 The Procter & Gamble Company Wet granulating method
US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
PL193273B1 (pl) 1997-12-22 2007-01-31 Euro Celtique Sa Postać dawkowania doustnego
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US8545880B2 (en) * 1999-02-26 2013-10-01 Andrx Pharmaceuticals, Llc Controlled release oral dosage form
US6210716B1 (en) 1999-02-26 2001-04-03 Andrx Pharmaceuticals, Inc. Controlled release bupropion formulation
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR101476574B1 (ko) 1999-10-29 2014-12-24 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
CN1423559A (zh) 2000-02-08 2003-06-11 欧罗赛铁克股份有限公司 包含阿片样激动剂和拮抗剂的控释组合物
PT1257277E (pt) * 2000-02-24 2005-09-30 Pharmacia & Upjohn Co Llc Novas combinacoes de farmacos
US6855721B1 (en) 2000-07-28 2005-02-15 Indevus Pharmaceuticals, Inc. Methods and compositions for alleviating stuttering
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
DE60238756D1 (de) 2001-05-11 2011-02-10 Endo Pharmaceuticals Inc Opioid enthaltende arzneiform gegen missbrauch
US7943173B2 (en) 2001-07-18 2011-05-17 Purdue Pharma L.P. Pharmaceutical combinations of oxycodone and naloxone
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
DE60232417D1 (de) 2001-08-06 2009-07-02 Euro Celtique Sa Opioid-agonist-formulierungen mit freisetzbarem und sequestriertem antagonist
WO2003013433A2 (en) 2001-08-06 2003-02-20 Euro-Celtique S.A. Sequestered antagonist formulations
EP1429728A1 (en) * 2001-08-29 2004-06-23 SRL Technologies, Inc. Sustained release preparations
US20030180249A1 (en) * 2002-03-18 2003-09-25 Khanna Satish Chandra Dosage forms for hygroscopic active ingredients
CA2478523A1 (en) 2002-04-05 2003-10-16 Euro-Celtique S.A. Matrix for sustained, invariant and independent release of active compounds
EP2422772A3 (en) 2002-09-20 2012-04-18 Alpharma, Inc. Sequestering subunit and related compositions and methods
US6893660B2 (en) * 2002-11-21 2005-05-17 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions without a stabilizer
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
TWI347201B (en) 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
AU2004270188B8 (en) * 2003-09-03 2010-04-29 Mallinckrodt Inc. Granular sustained release preparation and production thereof
US20050181050A1 (en) * 2004-01-28 2005-08-18 Collegium Pharmaceutical, Inc. Dosage forms using drug-loaded ion exchange resins
MXPA06012564A (es) * 2004-04-27 2007-01-31 Medicinova Inc Derivados de acido fenoxialquilcarboxilico en el tratamiento de enfermedades inflamatorias.
AU2005244401B2 (en) * 2004-05-14 2009-01-22 Green Cross Corp. Neuroprotective properties of dextrorotatory morphinans
EP1604666A1 (en) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
US20080095842A1 (en) * 2004-12-06 2008-04-24 Antarkar Amit K Rapidly Disintegrating Taste Masked Compositions and a Process for Its Preparations
WO2006081518A2 (en) * 2005-01-28 2006-08-03 Collegium Pharmaceutical, Inc. Non-ionic non-aqueous vehicles for topical and oral administration of carrier-complexed active agents
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
US8343546B2 (en) * 2005-09-13 2013-01-01 Coating Place, Inc. Ion exchange resin treated to control swelling
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
EP2018160B1 (en) 2006-03-16 2011-12-14 Tris Pharma, Inc. Modified release formulations containing drug-ion exchange resin complexes
HUE032156T2 (en) 2006-06-19 2017-09-28 Alpharma Pharmaceuticals Llc Pharmaceutical preparations
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
WO2009088385A1 (en) * 2008-01-04 2009-07-16 Capricorn Pharma Inc. Resin-complex granulation for water-soluble drugs and associated methods
ES2706407T3 (es) 2009-03-10 2019-03-28 Euro Celtique Sa Composiciones farmacéuticas de liberación inmediata que comprenden oxicodona y naloxona
US20120107381A1 (en) * 2009-05-13 2012-05-03 Relypsa, Inc. Powder formulations of potassium-binding active agents
JP2013119550A (ja) 2011-12-08 2013-06-17 Medicinova Inc 非アルコール性脂肪性肝疾患及び非アルコール性脂肪性肝炎の処置方法
US8962687B2 (en) 2012-12-05 2015-02-24 Medicinova, Inc. Method of treating liver disorders
WO2014167440A1 (en) * 2013-03-26 2014-10-16 Wockhardt Limited Modified release pharmaceutical compositions of cyclobenzaprine or salts thereof
AU2014295042B2 (en) 2013-07-23 2017-03-30 Mundipharma Pty Limited A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
US20150031769A1 (en) 2013-07-25 2015-01-29 Medicinova, Inc. Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels
US9346754B2 (en) 2014-05-08 2016-05-24 Medicinova, Inc. Method of treating advanced non-alcoholic steatohepatitis
US20150321989A1 (en) 2014-05-08 2015-11-12 Medicinova, Inc. Method of treating idiopathic pulmonary fibrosis
CN106470678A (zh) 2014-06-02 2017-03-01 美迪诺亚公司 抑制或治疗纤维化的方法
WO2016085998A1 (en) 2014-11-26 2016-06-02 Medicinova, Inc. Combination of ibudilast and riluzole and methods of using same
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
CA3034895A1 (en) 2016-08-26 2018-03-01 Exciva Ug (Haftungsbeschrankt) Compositions and methods thereof
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
CA3217719A1 (en) 2021-05-28 2022-12-01 Kazuko Matsuda Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB791281A (en) * 1955-01-13 1958-02-26 Genatosan Ltd Pharmaceutical products
GB822728A (en) * 1955-07-14 1959-10-28 Pfizer & Co C Vitamin products and process of preparing same
GB835932A (en) * 1956-03-27 1960-05-25 Ciba Ltd Process for the manufacture of therapeutic tablet granulations
FR792M (da) * 1959-11-13 1961-09-11
US3138525A (en) * 1961-06-16 1964-06-23 Hoffmann La Roche Castor wax-amprotropine-resin compositions
GB982150A (en) * 1961-09-29 1965-02-03 Glaxo Group Ltd Therapeutic resin complexes
BE635819A (da) * 1962-08-06
DE2706660A1 (de) * 1977-02-17 1978-08-24 Merck Patent Gmbh Ascorbinsaeure enthaltende granulate und verfahren zu ihrer herstellung
GB1566609A (en) * 1977-03-10 1980-05-08 Reckitt & Colmann Prod Ltd Pharmaceutical compositions containing cholestyramine and alginic acid
US4221778A (en) * 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
DE2929456A1 (de) * 1979-07-20 1981-02-05 Lentia Gmbh Zusammensetzung mit verlaengerter broncholytischer und tokolytischer wirksamkeit, ein verfahren zu deren herstellung und broncholytisch und tokolytisch wirkendes mittel
US4404346A (en) * 1980-08-05 1983-09-13 Rohm And Haas Company Production of powdered resin and the powdered resin so produced
US4369175A (en) * 1981-07-27 1983-01-18 Ciba-Geigy Corporation Process for the manufacture of prolonged action vincamine preparations, the vincamine preparations so obtained, and medicaments containing them
CH655507B (da) * 1983-01-12 1986-04-30
US4847362A (en) * 1985-02-01 1989-07-11 New York University Method for purifying antihemophilic factor
EP0200252B1 (en) * 1985-05-02 1999-03-10 Yamanouchi Europe B.V. Tablets comprising trimethoprim and a sulfonamide
EP0199855A1 (en) * 1985-05-02 1986-11-05 Gist-Brocades N.V. Tablets comprising tromethoprim and a sulfonamide
CA1273981A (en) * 1985-12-05 1990-09-11 Mitsubishi Materials Corporation Electric motor having rotor and stator provided with conical portions loosely fitted with each other
US4788055A (en) * 1985-12-09 1988-11-29 Ciba-Geigy Corporation Resinate sustained release dextromethorphan composition
DD249634B1 (de) * 1986-06-04 1988-09-21 Bitterfeld Chemie Cholesterolsenkendes mittel und verfahren zu seiner herstellung
IL90245A (en) * 1988-05-11 1994-04-12 Glaxo Group Ltd Resin adsorption containing ranitidine together with synthetic resin replaces cations, its preparation and pharmaceutical preparations containing it

Also Published As

Publication number Publication date
ATE123218T1 (de) 1995-06-15
EP0368682A1 (en) 1990-05-16
GB2225941B (en) 1992-12-09
IE893625L (en) 1990-05-11
AU4453089A (en) 1990-05-17
DE68922894T2 (de) 1996-01-11
JPH02243618A (ja) 1990-09-27
DE68922894D1 (de) 1995-07-06
DK564589D0 (da) 1989-11-10
GB2225941A (en) 1990-06-20
ES2075061T3 (es) 1995-10-01
US5071646A (en) 1991-12-10
EP0368682B1 (en) 1995-05-31
JP2825202B2 (ja) 1998-11-18
DK175154B1 (da) 2004-06-21
AU621949B2 (en) 1992-03-26
GB8925492D0 (en) 1989-12-28
CA2002492A1 (en) 1990-05-11

Similar Documents

Publication Publication Date Title
DK564589A (da) Farmaceutisk ionbytterharpikssammensaetning
DE68913979D1 (de) Kationenaustauscherharze und carboxylgruppenhaltige Kunstharze enthaltende Arzneizubereitungen mit verzögerter Wirkstofffreisetzung.
WO1997009036A3 (en) Improved pharmaceutical ion exchange resin composition
GB9018940D0 (en) Dosage device and preparation and use thereof
DK473889A (da) Granula
DE69000881T2 (de) 2-propylvaleriansaeure enthaltende arzneizubereitung mit verzoegerter wirkstofffreigabe.
BR9001637A (pt) Granulado efervescente,processo para sua preparacao,concentrado de substancia ativa pesticida e processo para sua preparacao
IE891527L (en) Drug absorbates
IE861205L (en) Effervescent therapeutic composition
EA199900075A1 (ru) Гранулят для получения быстрораспадающихся и быстрорастворяющихся композиций, содержащих большое количество лекарственного средства
DE69414904D1 (de) Silikat-Polymer enthaltende pharmazeutische Zusammensetzungen
DE68902300T2 (de) Pharmazeutische loesung enthaltend salbutamol und cromoglycinsaeure.
WO1997010810A3 (en) Pharmaceutical granules
DE3478397D1 (en) Pyrethroid-containing pharmaceutical compositions
AU570446B2 (en) Dipyridamole controlled release compositon
KR960003718A (ko) 말초신경병 및 중추신경변성병의 치료에 유용한 의약의 제조를 위한 이펜프로딜 및 그 부분입체이성질체의 이용
FR2670675B1 (fr) Procede de preparation de formes pharmaceutiques stables a base d'acide acetylsalicylique ou de ses sels.
ITMI910660V0 (it) Sistema per la somministrazione endocavitaria di principi attivi da miscelare al momento dell'uso
JPS643123A (en) Remedy for skin inflammation
BR1101024A (pt) Sistema terapêutico de liberação controlada para formulações relacionadas a formas farmacêuticas lìquidas

Legal Events

Date Code Title Description
PUP Patent expired