ES2073416T3 - Poliprenoles y fosfatos de poliprenilo para la inhibicion de metastasis de tumores. - Google Patents

Poliprenoles y fosfatos de poliprenilo para la inhibicion de metastasis de tumores.

Info

Publication number
ES2073416T3
ES2073416T3 ES89112422T ES89112422T ES2073416T3 ES 2073416 T3 ES2073416 T3 ES 2073416T3 ES 89112422 T ES89112422 T ES 89112422T ES 89112422 T ES89112422 T ES 89112422T ES 2073416 T3 ES2073416 T3 ES 2073416T3
Authority
ES
Spain
Prior art keywords
inhibition
tumor metastasis
polyprenols
unit
polyprenyl phosphates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89112422T
Other languages
English (en)
Inventor
Yasushi Okamoto
Yoshiyuki Tahara
Yoshio Mishima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Application granted granted Critical
Publication of ES2073416T3 publication Critical patent/ES2073416T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LOS FOSFATOS POLIPRENOLES Y POLIPRENILOS SON DE LA FORMULA EN DONDE REPRESENTA UNA UNIDAD DE TRANS-ISOPRENO, REPRESENTA UNA UNIDAD CIS-ISOPRENO, REPRESENTA UNA UNIDAD DE DIHIDROISOPRENO, L ES UN ENTERO DE 2 A 8, M ES 0 O UN ENTERO DE 5 A 18, N ES 0 O 1, LA SUMA DE L Y M ESTA EN EL MARGEN DE 8 A 20, Y X REPRESENTA UN ATOMO DE HIDROGENO O -PO3MM'' EN DONDE M Y M'' PUEDEN SER LO MISMO O DISTINTOS Y CADA UNO ES UN ATOMO DE HIDROGENO O UN CATION MONOVALENTE O M Y M'' FORMAN JUNTOS UN CATION DIVALENTE. SE USAN COMO UN MEDICAMENTO PARA LA INHIBICION DE METASTASIS TUMORAL.
ES89112422T 1988-07-13 1989-07-07 Poliprenoles y fosfatos de poliprenilo para la inhibicion de metastasis de tumores. Expired - Lifetime ES2073416T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63172638A JP2714402B2 (ja) 1988-07-13 1988-07-13 癌転移抑制剤

Publications (1)

Publication Number Publication Date
ES2073416T3 true ES2073416T3 (es) 1995-08-16

Family

ID=15945591

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89112422T Expired - Lifetime ES2073416T3 (es) 1988-07-13 1989-07-07 Poliprenoles y fosfatos de poliprenilo para la inhibicion de metastasis de tumores.

Country Status (7)

Country Link
US (1) US5004735A (es)
EP (1) EP0350801B1 (es)
JP (1) JP2714402B2 (es)
AU (1) AU619022B2 (es)
CA (1) CA1337176C (es)
DE (1) DE68922033T2 (es)
ES (1) ES2073416T3 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073572A (en) * 1990-02-16 1991-12-17 Harbor Branch Oceanographic Institution, Inc. Bioactive metabolites from cribrochalina vasculum
ES2133278T3 (es) * 1991-10-07 1999-09-16 Tno Uso de analogos de pirofosfato de poliisoprenilo para inhibir la isoprenilacion de proteinas.
JP3166991B2 (ja) * 1992-08-17 2001-05-14 日清製粉株式会社 （ｓ）−２，３−ジヒドロポリプレノール化合物を有効成分とする癌増殖抑制および／または癌転移抑制剤
PL178766B1 (pl) * 1992-12-16 2000-06-30 Basf Ag Nowe peptydy
US5654273A (en) * 1994-09-22 1997-08-05 Children's Medical Center Corporation Synducin mediated modulation of tissue repair
GB2310138A (en) * 1996-02-19 1997-08-20 Juris Rubens Immunomodulating plant polyprenols
JP2001524939A (ja) * 1996-12-12 2001-12-04 ファルマシア・アンド・アップジョン・カンパニー ジヒドロポリプレノールの油組成物
RU2177788C2 (ru) * 1998-06-10 2002-01-10 Данилов Леонид Леонидович Средство для профилактики и лечения инфекционных заболеваний и коррекции патологических состояний живого организма
RU2129867C1 (ru) * 1998-06-10 1999-05-10 Данилов Леонид Леонидович Средство для профилактики и лечения инфекционных заболеваний и коррекции патологических состояний живого организма
US6525035B1 (en) 1999-06-10 2003-02-25 Sass & Sass, Inc. Therapeutic composition and methods
TW200617393A (en) * 2004-11-22 2006-06-01 Univ Nat Cheng Kung Method for testing lectin
CN100391962C (zh) * 2005-06-24 2008-06-04 中国林业科学研究院林产化学工业研究所 聚戊烯基磷酸酯合成方法
RU2327448C1 (ru) * 2007-05-23 2008-06-27 Виктор Иванович Рощин Средство для лечения зависимости от этилового спирта и/или от наркотиков, фармацевтическая композиция, активный ингредиент фармацевтической композиции, способ лечения зависимости от этилового спирта и/или от наркотиков для лечения психосоматических и неврологических осложнений у алкоголиков и/или наркоманов
US9872867B2 (en) 2008-06-06 2018-01-23 Tanya Kuritz Methods and compositions for modulation of innate immunity
RU2425669C1 (ru) * 2010-04-13 2011-08-10 Общество С Ограниченной Ответственностью "Гамаветфарм" Средство для профилактики и лечения острого и хронического панкреатита
RU2427284C1 (ru) * 2010-06-29 2011-08-27 Общество С Ограниченной Ответственностью "Гамаветфарм" Биологически активная добавка и способ ее получения
JP5058332B2 (ja) 2010-07-14 2012-10-24 住友ゴム工業株式会社 イソプレンオリゴマー、ポリイソプレン、及びこれらの製造方法、ゴム組成物、並びに空気入りタイヤ
WO2014042027A1 (ja) * 2012-09-12 2014-03-20 住友ゴム工業株式会社 イソプレンオリゴマー、ポリイソプレン、及びこれらの製造方法、ゴム組成物、並びに空気入りタイヤ
RU2526179C1 (ru) * 2013-03-24 2014-08-20 Общество С Ограниченной Ответственностью "Гамаветфарм" Средство для снижения репродукции вируса гепатита с
RU2605264C1 (ru) * 2015-12-02 2016-12-20 Общество С Ограниченной Ответственностью "Гамаветфарм" Средство для растворения желчных камней и лечения желчнокаменной болезни

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0229653B2 (ja) * 1982-02-19 1990-07-02 Eisai Co Ltd Seiganzai
JPS6067424A (ja) * 1983-09-22 1985-04-17 Nisshin Flour Milling Co Ltd 制癌剤
JPS6239521A (ja) * 1985-08-14 1987-02-20 Kuraray Co Ltd 免疫増強剤
JPH0759504B2 (ja) * 1986-01-23 1995-06-28 エーザイ株式会社 ポリプレニルアルコ−ル含有注射剤

Also Published As

Publication number Publication date
EP0350801A3 (en) 1991-12-27
JPH0225415A (ja) 1990-01-26
EP0350801B1 (en) 1995-04-05
CA1337176C (en) 1995-10-03
AU3808289A (en) 1991-05-09
DE68922033T2 (de) 1995-08-24
EP0350801A2 (en) 1990-01-17
US5004735A (en) 1991-04-02
JP2714402B2 (ja) 1998-02-16
AU619022B2 (en) 1992-01-16
DE68922033D1 (de) 1995-05-11

Similar Documents

Publication Publication Date Title
ES2073416T3 (es) Poliprenoles y fosfatos de poliprenilo para la inhibicion de metastasis de tumores.
ATE92930T1 (de) Saponinkomplexe mit phospholipiden und sie enthaltende pharmazeutische und kosmetische zusammensetzungen.
AR240946A2 (es) "compuesto de sal de trialquilsulfonio y sulfoxonio de n-fosfonometilglicina y composicion herbicida que lo cimprende"
DK169683A (da) Mundplejemiddel
SE7709050L (sv) Sett att framstella drageer
BG42837A3 (bg) Метод за получаване на имуноглобулинови производни на винка алкалоиди
ES2121993T3 (es) Derivados de 4-oxo-2-tioxoimidazolidina como sustancias inhibidoras de la agregacion de plaquetas sanguineas.
ES2042547T3 (es) Un procedimiento para preparar una formulacion de tableta a capsula de liberacion sostenida.
ES8402297A1 (es) Un procedimiento de preparacion de derivados de imidazo-(1,2-)piridina.
DE68903840D1 (de) Verwendung von 3'-azido-deoxythymidin zur herstellung eines arzneimittels zur behandlung von humanen brustcarzinomen.
ES8801168A1 (es) Procedimiento para la obtencion de un compuesto de platino para utilizar en quimioterapia del cancer.
FR2495635B1 (fr) Production d'urokinase humaine
ATE79255T1 (de) Wirkstoffe zur verhuetung von tumormetastasen.
SE7702519L (sv) Antitumormedel
ES2019634B3 (es) Terapia con clorfeniramina.
DE69232852D1 (de) Verwendung von topotecan in der behandlung von nichtkleinzelligen lungenkarzinomen
DK484685D0 (da) Micellulaere partikelkompositioner til maalrettet tilfoersel til tumorer i mennesker og kompositionernes anvendelse
MA20552A1 (fr) Alkylacarboxamides de pyridylalkylamines,leurs preparations et leurs utilisations
SE8601733L (sv) 1-hydroxi-8-acyloxi-10-acyl-antroner, sett att framstella dessa och deras anvendning human- och veterinermedicin och i kosmetika
ES2174007T3 (es) Derivados de biotina.
AR245336A1 (es) Procedimiento para la preparacion de microplantas a traves de la formacion incrementada de multiples brotes.
SE8301280D0 (sv) Dentifrice preparation
USD232272S (en) Tree seedling carrier
BG45853A3 (bg) Метод за получаване на бензамидни съединения
ATE36957T1 (de) N,n-diethyl-5-methyl-2h,1-benzothiopyrano-(4,3, - cd)-indazol-2-ethanamine, diese enthaltende zubereitungen und ihre verwendung.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 350801

Country of ref document: ES