ES2071955T3 - Nuevos derivados de aminoalquilcetona, su procedimiento de preparacion y sus aplicaciones en terapeutica. - Google Patents

Nuevos derivados de aminoalquilcetona, su procedimiento de preparacion y sus aplicaciones en terapeutica.

Info

Publication number
ES2071955T3
ES2071955T3 ES91403374T ES91403374T ES2071955T3 ES 2071955 T3 ES2071955 T3 ES 2071955T3 ES 91403374 T ES91403374 T ES 91403374T ES 91403374 T ES91403374 T ES 91403374T ES 2071955 T3 ES2071955 T3 ES 2071955T3
Authority
ES
Spain
Prior art keywords
therapeutics
applications
preparation procedure
amino alkyl
sub
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91403374T
Other languages
English (en)
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of ES2071955T3 publication Critical patent/ES2071955T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE FORMULA: EN LA QUE A ES ELEGIDO ENTRE LOS GRUPOS PIRROLIDINO, PIPERIDINO, MORFOLINO, 1-IMIDAZOLILE, HEXAMETILENO IMINO, 1-PIPERAZINILO, ESTANDO ESTOS GRUPOS NO SUSTITUIDOS O PUDIENDO LLEVAR 1 O 2 SUSTITUYENTES ELEGIDOS ENTRE LOS GRUPOS ALQUILO EN C SUB 1-C SUB 3 E HIDROXIALQUILO EN C SUB 1-C SUB 3, Y LAS SALES DE ADICION DE ESTOS COMPUESTOS CON ACIDOS FARMACEUTICAMENTE ACEPTABLES. ESTOS COMPUESTOS SE PUEDEN UTILIZAR EN TERAPIA COMO VASODILATADORES PERIFERICOS
ES91403374T 1990-12-12 1991-12-12 Nuevos derivados de aminoalquilcetona, su procedimiento de preparacion y sus aplicaciones en terapeutica. Expired - Lifetime ES2071955T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9015591A FR2670492B1 (fr) 1990-12-12 1990-12-12 Nouveaux derives d'aminoalkylcetone, leur procede de preparation et leurs applications en therapeutique.

Publications (1)

Publication Number Publication Date
ES2071955T3 true ES2071955T3 (es) 1995-07-01

Family

ID=9403177

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91403374T Expired - Lifetime ES2071955T3 (es) 1990-12-12 1991-12-12 Nuevos derivados de aminoalquilcetona, su procedimiento de preparacion y sus aplicaciones en terapeutica.

Country Status (23)

Country Link
US (1) US5446060A (es)
EP (1) EP0490769B1 (es)
JP (1) JPH04334379A (es)
KR (1) KR920012074A (es)
CN (1) CN1029737C (es)
AT (1) ATE121397T1 (es)
AU (1) AU648126B2 (es)
CA (1) CA2057138A1 (es)
CS (1) CS375591A3 (es)
DE (1) DE69109072T2 (es)
DK (1) DK0490769T3 (es)
ES (1) ES2071955T3 (es)
FI (1) FI915809L (es)
FR (1) FR2670492B1 (es)
HU (1) HUT62002A (es)
IE (1) IE914311A1 (es)
LT (1) LTIP614A (es)
LV (1) LV10266B (es)
MX (1) MX9102514A (es)
NO (1) NO914845L (es)
NZ (1) NZ240809A (es)
PT (1) PT99726A (es)
ZA (1) ZA919754B (es)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3189600A (en) * 1963-01-03 1965-06-15 Ciba Geigy Corp Alpha-halogen-gamma tertiary aminobutyrophenones and the corresponding thophenes
DE1217396B (de) * 1963-07-04 1966-05-26 Laboratorie Roger Bellon, Neuilly-sur-Seine (Frankreich) Verfahren zur Herstellung von 1 - (Thienyl-21) - l-oxo-2-amino-propanen
US3417087A (en) * 1965-12-27 1968-12-17 Research Corp 3(aminopropionyl)benzothiophenes
FR2134218A1 (en) * 1971-04-27 1972-12-08 Penciolelli Madeleine Phloroglucinol aminoketones - vasodilators and antispasmodics
FR2184503A2 (en) * 1972-05-19 1973-12-28 Cluzel Roger Alkyl 2-amino-3-(2-thenoyl)propionates - with antibacterial activity
US4009184A (en) * 1974-06-06 1977-02-22 Kali-Chemie Aktiengesellschaft Amino carbonyl derivatives of benzofurans, processes for their production, and pharmaceutical compositions containing the same 2-phenyl-3-[3-dialkylaminopropanoyl]benzofuran compounds
FR2291755A2 (fr) * 1974-11-21 1976-06-18 Delalande Sa Nouveaux benzoyl-2' eth-1' yl)-1 (cinnamyl-4'' piperazin-1'' yl methyl)-2 benzimidazoles, leur procede de preparation et leur application en therapeutique
FR2305982A1 (fr) * 1975-04-03 1976-10-29 Innothera Lab Sa Nouvelles benzothienyl amino (propyl et butyl) cetones, leur procede de preparation et leur application en therapeutique
FR2305981A1 (fr) * 1975-04-03 1976-10-29 Innothera Lab Sa Nouvelles benzothienyl aminoethyl cetones, leur procede de preparation et leur application en therapeutique
FR2453172A1 (fr) * 1979-04-06 1980-10-31 Innothera Lab Sa Nouvelles (thienyl-2) amino-1 butyl cetones, leur procede de preparation et leur application en therapeutique
US4299769A (en) * 1980-04-28 1981-11-10 American Cyanamid Company ω-Heteroaroyl(propionyl or butyryl)-L-prolines
JPS6028973A (ja) * 1983-07-28 1985-02-14 Kaken Pharmaceut Co Ltd チオフェン誘導体
DE3508398A1 (de) * 1985-03-08 1986-11-06 Hoechst Ag, 6230 Frankfurt Fungizide mittel auf der basis von 3-(hetero)-arylpropylaminen sowie neue (hetero)-aryl-propylamine und verfahren zu ihrer herstellung
FR2655043B1 (fr) * 1989-11-24 1992-02-07 Adir Nouveaux derives du thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Also Published As

Publication number Publication date
CN1029737C (zh) 1995-09-13
PT99726A (pt) 1992-10-30
AU8894091A (en) 1992-07-09
CS375591A3 (en) 1992-06-17
FI915809A7 (fi) 1992-06-13
KR920012074A (ko) 1992-07-25
FI915809L (fi) 1992-06-13
FR2670492A1 (fr) 1992-06-19
ZA919754B (en) 1993-06-11
IE914311A1 (en) 1992-06-17
MX9102514A (es) 1992-09-01
FR2670492B1 (fr) 1994-11-04
DE69109072D1 (de) 1995-05-24
FI915809A0 (fi) 1991-12-10
CA2057138A1 (en) 1992-06-13
ATE121397T1 (de) 1995-05-15
JPH04334379A (ja) 1992-11-20
EP0490769A1 (fr) 1992-06-17
NO914845L (no) 1992-06-15
HU913903D0 (en) 1992-02-28
LV10266A (lv) 1994-10-20
AU648126B2 (en) 1994-04-14
LTIP614A (en) 1994-12-27
EP0490769B1 (fr) 1995-04-19
NZ240809A (en) 1992-11-25
DK0490769T3 (da) 1995-07-17
US5446060A (en) 1995-08-29
HUT62002A (en) 1993-03-29
CN1062353A (zh) 1992-07-01
NO914845D0 (no) 1991-12-10
DE69109072T2 (de) 1995-09-14
LV10266B (en) 1995-04-20

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