ES2065181T3 - Dispositivo de suministro iontoforetico y procedimiento para su fabricacion. - Google Patents
Dispositivo de suministro iontoforetico y procedimiento para su fabricacion.Info
- Publication number
- ES2065181T3 ES2065181T3 ES92908542T ES92908542T ES2065181T3 ES 2065181 T3 ES2065181 T3 ES 2065181T3 ES 92908542 T ES92908542 T ES 92908542T ES 92908542 T ES92908542 T ES 92908542T ES 2065181 T3 ES2065181 T3 ES 2065181T3
- Authority
- ES
- Spain
- Prior art keywords
- agent
- vol
- typically
- case
- iontophoretical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/0436—Material of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Electrotherapy Devices (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Treatment Of Water By Ion Exchange (AREA)
- Sampling And Sample Adjustment (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE PRESENTA UN DISPOSITIVO DE SUMINISTRO IONTOFORETICO, TRANSDERMICO, ELECTRICAMENTE ALIMENTADO (10, 20) Y UN METODO PARA FABRICAR EL MISMO. EL DISPOSITIVO UTILIZA UNOS ELECTRODOS (8, 9) COMPUESTOS DE UNA MEZCLA SUBSTANCIALMENTE HOMOGENEA DE UNA MATRIZ POLIMERICA QUE CONTIENE ALREDEDOR DE UN 5 Y UN 50% DE SU VOLUMEN DE UN RELLENO CONDUCTOR QUE FORMA UNA RED CONDUCTORA A TRAVES DE LA MATRIZ Y HASTA ALREDEDOR DE UN 50% DEL VOLUMEN DE UN AGENTE QUE SERA IONTOFORETICAMENTE SUMINISTRADO A TRAVES DE LA PIEL. EN EL CASO DEL ELECTRODO DONANTE, EL AGENTE ES TIPICAMENTE UNA DROGA Y PREFERIBLEMENTE UNA SAL DE UNA DROGA SOLUBLE EN AGUA. EN EL CASO DEL ELECTRODO CONTRARIO, EL AGENTE ES TIPICAMENTE UNA SAL DE ELECTROLITO. LA MEZCLA HOMOGENEA ELIMINA LA NECESIDAD DE ELECTRODOS SEPARADOS Y AGENTES QUE CONTENGAN CAPAS QUE REQUIERAN LAMINACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66771491A | 1991-03-11 | 1991-03-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2065181T3 true ES2065181T3 (es) | 1995-02-01 |
Family
ID=24679337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92908542T Expired - Lifetime ES2065181T3 (es) | 1991-03-11 | 1992-03-09 | Dispositivo de suministro iontoforetico y procedimiento para su fabricacion. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5543098A (es) |
EP (1) | EP0575508B1 (es) |
JP (1) | JPH06505413A (es) |
AT (1) | ATE112496T1 (es) |
AU (1) | AU1586692A (es) |
DE (1) | DE69200506T2 (es) |
DK (1) | DK0575508T3 (es) |
ES (1) | ES2065181T3 (es) |
IE (1) | IE920763A1 (es) |
MX (1) | MX9201029A (es) |
PT (1) | PT100215A (es) |
WO (1) | WO1992015365A1 (es) |
ZA (1) | ZA921736B (es) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5322520A (en) * | 1992-11-12 | 1994-06-21 | Implemed, Inc. | Iontophoretic structure for medical devices |
US6060000A (en) * | 1992-11-12 | 2000-05-09 | Implemed, Inc. | Iontophoretic material containing carbon and metal granules |
FR2722993B1 (fr) * | 1994-07-26 | 1996-09-27 | Elf Aquitaine | Dispositif d'ionophorese comportant au moins un ensemble electrode a electrode composite reversible |
JPH08155041A (ja) * | 1994-12-05 | 1996-06-18 | Advance Co Ltd | イオントフォレシス用新規高能率電極システム |
BR9609358A (pt) * | 1995-06-05 | 1999-05-18 | Alza Corp | Dispositivo para distribuição transdérmica por eletrotransporte fentanil e sufentanil |
DE69637100T2 (de) * | 1995-09-29 | 2008-01-17 | Vyteris, Inc. | Kostengünstige elektroden für eine iontophoretische vorrichtung |
US6254883B1 (en) | 1996-01-30 | 2001-07-03 | Novagent Oy | Composition for transdermal delivery of drugs |
JP3459724B2 (ja) * | 1996-03-17 | 2003-10-27 | 久光製薬株式会社 | イオントフォレーシス用電極デバイス |
CA2250195C (en) * | 1996-04-16 | 2004-08-17 | Implemed, Inc. | Iontophoretic material |
FI962461A (fi) * | 1996-06-13 | 1997-12-14 | Novagent Oy | Menetelmä ja farmaseuttinen kompositio ihon läpi tehtävään lääkkeen antoon |
US6246904B1 (en) * | 1996-12-17 | 2001-06-12 | Alza Corporation | Electrotransport drug delivery reservoirs containing inert fillers |
WO1999018797A1 (en) | 1997-10-09 | 1999-04-22 | Emory University | Method and devices for transdermal delivery of lithium |
DK1051219T3 (da) * | 1998-01-28 | 2005-01-10 | Alza Corp | Elektrokemisk reaktive katoder for en elektrotransportanordning |
EP0962233A1 (fr) * | 1998-06-03 | 1999-12-08 | Sport-Elec S.A. | Dispositif d'electrode pour electrotherapie |
US6192270B1 (en) * | 1998-08-14 | 2001-02-20 | Genetronics, Inc. | Apparatus and method for the delivery of drugs and genes into tissue |
BR0008123A (pt) | 1999-02-10 | 2001-11-13 | Gmp Drug Delivery Inc | Dispositivo baseado em emplastro para aumentar aliberação local de um agente de tratamento paradentro de tecidos alvo, e, processo de liberaçãode um agente de tratamento para dentro detecidos alvo de uma vesìcula corporal |
KR20020048425A (ko) * | 1999-09-30 | 2002-06-22 | 해리 제이. 레온 하르트 | 마이크로전자 어레이 상의 생체분자 부착 부위 |
US6303082B1 (en) * | 1999-12-15 | 2001-10-16 | Nanogen, Inc. | Permeation layer attachment chemistry and method |
US6629968B1 (en) * | 2000-06-30 | 2003-10-07 | Vyteris, Inc. | Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode |
US20140163060A1 (en) * | 2001-10-12 | 2014-06-12 | Monosol Rx, Llc | Films and Drug Delivery Systems Made Therefrom |
WO2003037425A1 (en) * | 2001-10-31 | 2003-05-08 | R & R Ventures Incorporation | Iontophoresis device |
US7349733B2 (en) * | 2001-11-02 | 2008-03-25 | Ceramatel, Inc. | Iontophoretic drug delivery systems |
US6960298B2 (en) | 2001-12-10 | 2005-11-01 | Nanogen, Inc. | Mesoporous permeation layers for use on active electronic matrix devices |
US6527955B1 (en) * | 2001-12-28 | 2003-03-04 | Policell Technologies, Inc. | Heat-activatable microporous membrane and its uses in batteries |
US6815123B2 (en) * | 2001-12-28 | 2004-11-09 | Policell Technologies, Inc. | Lithium-ion battery using heat-activatable microporous membrane |
US6998193B2 (en) | 2001-12-28 | 2006-02-14 | Policell Technologies, Inc. | Microporous membrane and its uses thereof |
US6775570B2 (en) | 2002-02-04 | 2004-08-10 | Ceramatec, Inc. | Iontophoretic treatment device |
US7047069B2 (en) | 2002-02-04 | 2006-05-16 | Ceramatec, Inc. | Iontophoretic fluid delivery device |
DE10205373B4 (de) * | 2002-02-09 | 2007-07-19 | Aloys Wobben | Brandschutz |
US20040009398A1 (en) * | 2002-06-19 | 2004-01-15 | Dorfman Jay Robert | Zinc polymer thick film composition |
IL152575A (en) * | 2002-10-31 | 2008-12-29 | Transpharma Medical Ltd | A skin-to-skin transmission system of water-insoluble drugs |
IL152574A (en) | 2002-10-31 | 2009-09-22 | Transpharma Medical Ltd | A system for passing through the skin of dry items or dried medicines |
US7383084B2 (en) * | 2002-10-31 | 2008-06-03 | Transpharma Medical Ltd. | Transdermal delivery system for dried particulate or lyophilized medications |
US8133505B2 (en) | 2002-10-31 | 2012-03-13 | Transpharma Medical Ltd. | Transdermal delivery system for dried particulate or lyophilized medications |
IL152573A (en) * | 2002-10-31 | 2009-11-18 | Transpharma Medical Ltd | A system for the transmission through the skin of a medical preparation against vomiting and nausea |
US7662404B2 (en) * | 2002-10-31 | 2010-02-16 | Transpharma Medical Ltd. | Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides |
IL159273A0 (en) * | 2003-12-09 | 2004-06-01 | Transpharma Medical Ltd | Transdermal delivery system for sustained release of polypeptides |
JP4728631B2 (ja) * | 2004-11-30 | 2011-07-20 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
US7590444B2 (en) * | 2004-12-09 | 2009-09-15 | Tti Ellebeau, Inc. | Iontophoresis device |
JP4731931B2 (ja) * | 2005-02-03 | 2011-07-27 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
JP4793806B2 (ja) * | 2005-03-22 | 2011-10-12 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
JP2006346368A (ja) * | 2005-06-20 | 2006-12-28 | Transcutaneous Technologies Inc | イオントフォレーシス装置及びその製造方法 |
US20070027426A1 (en) * | 2005-06-24 | 2007-02-01 | Transcutaneous Technologies Inc. | Iontophoresis device to deliver active agents to biological interfaces |
US20090214625A1 (en) * | 2005-07-15 | 2009-08-27 | Mizuo Nakayama | Drug delivery patch |
JP2007037868A (ja) * | 2005-08-05 | 2007-02-15 | Transcutaneous Technologies Inc | 経皮投与装置及びその制御方法 |
US8295922B2 (en) | 2005-08-08 | 2012-10-23 | Tti Ellebeau, Inc. | Iontophoresis device |
US8386030B2 (en) | 2005-08-08 | 2013-02-26 | Tti Ellebeau, Inc. | Iontophoresis device |
US20070060860A1 (en) * | 2005-08-18 | 2007-03-15 | Transcutaneous Technologies Inc. | Iontophoresis device |
US20070088331A1 (en) * | 2005-08-18 | 2007-04-19 | Transcutaneous Technologies Inc. | Method and apparatus for managing active agent usage, and active agent injecting device |
US20090254018A1 (en) * | 2005-08-24 | 2009-10-08 | Mizuo Nakayama | Electrode assembly for freezing-type iontophoresis device |
US20100016781A1 (en) * | 2005-08-29 | 2010-01-21 | Mizuo Nakayama | Iontophoresis device selecting drug to be administered on the basis of information form sensor |
WO2007029611A1 (ja) * | 2005-09-06 | 2007-03-15 | Tti Ellebeau, Inc. | イオントフォレーシス装置 |
WO2007032446A1 (ja) | 2005-09-15 | 2007-03-22 | Tti Ellebeau, Inc. | ロッド型イオントフォレーシス装置 |
BRPI0616166A2 (pt) * | 2005-09-16 | 2011-06-07 | Tti Ellebeau Inc | dispositivo de iontoforese do tipo de cateter |
US20070083147A1 (en) * | 2005-09-30 | 2007-04-12 | Transcutaneous Technologies Inc. | Iontophoresis apparatus and method to deliver antibiotics to biological interfaces |
JPWO2007037476A1 (ja) * | 2005-09-30 | 2009-04-16 | Tti・エルビュー株式会社 | 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置 |
WO2007037475A1 (ja) * | 2005-09-30 | 2007-04-05 | Tti Ellebeau, Inc. | 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置 |
CA2664589A1 (en) | 2005-09-30 | 2007-04-12 | Tti Ellebeau, Inc. | Iontophoretic device and method of delivery of active agents to biological interface |
US20070093787A1 (en) * | 2005-09-30 | 2007-04-26 | Transcutaneous Technologies Inc. | Iontophoresis device to deliver multiple active agents to biological interfaces |
US20070197955A1 (en) * | 2005-10-12 | 2007-08-23 | Transcutaneous Technologies Inc. | Mucous membrane adhesion-type iontophoresis device |
JP4804904B2 (ja) * | 2005-12-09 | 2011-11-02 | Tti・エルビュー株式会社 | イオントフォレーシス装置包装品 |
WO2007079116A1 (en) * | 2005-12-28 | 2007-07-12 | Tti Ellebeau, Inc. | Electroosmotic pump apparatus and method to deliver active agents to biological interfaces |
US7744591B2 (en) * | 2005-12-29 | 2010-06-29 | Boston Scientific Scimed, Inc. | Foam electrode and method of use thereof during tissue resection |
US20080033398A1 (en) * | 2005-12-29 | 2008-02-07 | Transcutaneous Technologies Inc. | Device and method for enhancing immune response by electrical stimulation |
US20080004564A1 (en) * | 2006-03-30 | 2008-01-03 | Transcutaneous Technologies Inc. | Controlled release membrane and methods of use |
CN101460201A (zh) * | 2006-06-05 | 2009-06-17 | 防菌公司 | 聚合物基质、其用途和制造该聚合物基质的方法 |
WO2008005458A2 (en) * | 2006-07-05 | 2008-01-10 | Tti Ellebeau, Inc. | Delivery device having self-assembling dendritic polymers and method of use thereof |
US7687103B2 (en) * | 2006-08-31 | 2010-03-30 | Gamida For Life B.V. | Compositions and methods for preserving permeation layers for use on active electronic matrix devices |
MX2009002321A (es) * | 2006-09-05 | 2009-03-23 | Tti Ellebeau Inc | Sistemas, dispositivos y metodos de suministro transdermico de farmacos que utilizan suministros de energia inductiva. |
KR20090106492A (ko) | 2006-12-01 | 2009-10-09 | 티티아이 엘뷰 가부시키가이샤 | 경피성 전달 장치와 같은 장치에 전력을 제공하거나 제어하기 위한 시스템, 장치, 및 방법 |
US20080177219A1 (en) * | 2007-01-23 | 2008-07-24 | Joshi Ashok V | Method for Iontophoretic Fluid Delivery |
US20080188791A1 (en) * | 2007-02-02 | 2008-08-07 | Difiore Attilio E | Active iontophoresis delivery system |
US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
CN105902482A (zh) * | 2008-06-25 | 2016-08-31 | Fe3医学有限公司 | 用于经皮递送治疗有效量的铁的贴片和方法 |
AR074047A1 (es) * | 2008-09-09 | 2010-12-22 | Transcu Ltd | Sistemas, dispositivos, y metodos para suministrar energia a dispositivos, por ejemplo dispositivos de administracion transdermica y/o para controlarlos |
BRPI0918060A2 (pt) * | 2008-09-10 | 2015-12-01 | Transcu Ltd | aparelho e método de distribuição de líquidos viscosos a base de hpc em substratos porosos, por exemplo, processo contínuo a base de tecido. |
KR101344993B1 (ko) * | 2008-10-28 | 2013-12-24 | 오츠카 세이야쿠 가부시키가이샤 | 나한과 추출물 및 수크랄로스를 함유하는 저칼로리 음료 조성물 |
KR101674904B1 (ko) | 2009-02-26 | 2016-11-10 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 중재형 약물전달 시스템과 그 방법 |
US8821945B2 (en) | 2009-04-25 | 2014-09-02 | Fe3 Medical, Inc. | Method for transdermal iontophoretic delivery of chelated agents |
US20100312168A1 (en) * | 2009-06-09 | 2010-12-09 | Yoshimasa Yoshida | Long life high capacity electrode, device, and method of manufacture |
FR2983075B1 (fr) * | 2011-11-24 | 2014-08-15 | Ab7 Innovation | Procede de chargement de plaquette polymere en solution medicamenteuse ionisee amphiphile pour administration transdermique par iontophorese |
EP3129012A4 (en) | 2014-04-08 | 2017-10-11 | Teikoku Pharma USA, Inc. | Rivastigmine transdermal compositions and methods of using the same |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE410009C (de) * | 1923-12-25 | 1925-02-21 | Willi Reiche Dipl Ing | Sprungwellenschutz fuer die Induktionswicklungen elektrischer Apparate und Maschinen |
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-
1992
- 1992-03-09 WO PCT/US1992/001858 patent/WO1992015365A1/en active IP Right Grant
- 1992-03-09 EP EP92908542A patent/EP0575508B1/en not_active Expired - Lifetime
- 1992-03-09 PT PT100215A patent/PT100215A/pt not_active Application Discontinuation
- 1992-03-09 DE DE69200506T patent/DE69200506T2/de not_active Expired - Lifetime
- 1992-03-09 ZA ZA921736A patent/ZA921736B/xx unknown
- 1992-03-09 ES ES92908542T patent/ES2065181T3/es not_active Expired - Lifetime
- 1992-03-09 JP JP4508302A patent/JPH06505413A/ja active Pending
- 1992-03-09 MX MX9201029A patent/MX9201029A/es unknown
- 1992-03-09 AT AT92908542T patent/ATE112496T1/de not_active IP Right Cessation
- 1992-03-09 AU AU15866/92A patent/AU1586692A/en not_active Abandoned
- 1992-03-09 IE IE076392A patent/IE920763A1/en not_active Application Discontinuation
- 1992-03-09 DK DK92908542.1T patent/DK0575508T3/da active
-
1994
- 1994-02-17 US US08/197,665 patent/US5543098A/en not_active Expired - Lifetime
-
1996
- 1996-01-26 US US08/592,083 patent/US5618265A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5543098A (en) | 1996-08-06 |
ATE112496T1 (de) | 1994-10-15 |
DE69200506T2 (de) | 1995-02-02 |
EP0575508B1 (en) | 1994-10-05 |
PT100215A (pt) | 1994-04-29 |
DE69200506D1 (de) | 1994-11-10 |
AU1586692A (en) | 1992-10-06 |
EP0575508A1 (en) | 1993-12-29 |
JPH06505413A (ja) | 1994-06-23 |
IE920763A1 (en) | 1992-09-23 |
WO1992015365A1 (en) | 1992-09-17 |
MX9201029A (es) | 1992-09-01 |
DK0575508T3 (da) | 1994-11-14 |
ZA921736B (en) | 1992-11-25 |
US5618265A (en) | 1997-04-08 |
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