ES2059665T3 - Derivados de acido ciclopentenoheptanoico y metodo de preparacion de los mismos. - Google Patents

Derivados de acido ciclopentenoheptanoico y metodo de preparacion de los mismos.

Info

Publication number
ES2059665T3
ES2059665T3 ES89118400T ES89118400T ES2059665T3 ES 2059665 T3 ES2059665 T3 ES 2059665T3 ES 89118400 T ES89118400 T ES 89118400T ES 89118400 T ES89118400 T ES 89118400T ES 2059665 T3 ES2059665 T3 ES 2059665T3
Authority
ES
Spain
Prior art keywords
preparation
vinylene
chem
acid derivative
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89118400T
Other languages
English (en)
Inventor
Kevin Anthony Babiak
Arthur Lee Campbell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of ES2059665T3 publication Critical patent/ES2059665T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

EL INVENTO SE REFIERE A UN NUEVO DERIVADO DEL ACIDO CICLOPENTENEHEPTANOICO QUE TIENE LA FORMULA I EN LA QUE, R1 ES HIDROGENO, - COCH3, -CO - FENIL, O UN GRUPO DE PROTECCION HIDROXIL TAL COMO TETRAHIDROPIRANIL, TETRAHIDROFURANIL, O ALKISILIL TRIPE INFERIOR; EN DONDE R2 ES - CH2OR1, -COOH, -COOR, -CHO, -CH2-OSI(R12)3.
ES89118400T 1988-10-07 1989-10-04 Derivados de acido ciclopentenoheptanoico y metodo de preparacion de los mismos. Expired - Lifetime ES2059665T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/255,179 US4952710A (en) 1988-10-07 1988-10-07 Cyclopenteneheptenoic acid derivatives and method of preparation thereof

Publications (1)

Publication Number Publication Date
ES2059665T3 true ES2059665T3 (es) 1994-11-16

Family

ID=22967191

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89118400T Expired - Lifetime ES2059665T3 (es) 1988-10-07 1989-10-04 Derivados de acido ciclopentenoheptanoico y metodo de preparacion de los mismos.

Country Status (7)

Country Link
US (1) US4952710A (es)
EP (1) EP0362816B1 (es)
JP (1) JP2836860B2 (es)
AT (1) ATE97400T1 (es)
CA (1) CA2000179C (es)
DE (1) DE68910774T2 (es)
ES (1) ES2059665T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100575A (en) * 1989-09-08 1992-03-31 Fmc Corporation Thermally stable, reactive organometallic compositions containing copper
US5191109A (en) * 1990-02-02 1993-03-02 Sumitomo Chemical Company, Limited Process for preparing optically active cyclopentenones
US5618959A (en) * 1995-03-10 1997-04-08 Vivus Incorporated Process for preparing prostaglandin E1, E2 and analogs thereof using furylcopper reagents
KR101045935B1 (ko) 2009-03-11 2011-07-01 연성정밀화학(주) 프로스타글란딘 유도체의 제조방법
HU231185B1 (hu) * 2017-07-11 2021-07-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Eljárás Misoprostol előállítására és tisztítására

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL127841B1 (en) * 1980-04-01 1983-11-30 Egyt Gyogyszervegyeszeti Gyar Process for preparing derivatives of 2,6,10-trimethylundeca-1,3-diene-1-carboxylic acid

Also Published As

Publication number Publication date
EP0362816A1 (en) 1990-04-11
CA2000179A1 (en) 1990-04-07
EP0362816B1 (en) 1993-11-18
DE68910774D1 (de) 1993-12-23
DE68910774T2 (de) 1994-03-24
JPH02145532A (ja) 1990-06-05
ATE97400T1 (de) 1993-12-15
US4952710A (en) 1990-08-28
JP2836860B2 (ja) 1998-12-14
CA2000179C (en) 2000-05-02

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