JPS5721386A - Preparation of oxazolidinone derivative - Google Patents

Preparation of oxazolidinone derivative

Info

Publication number
JPS5721386A
JPS5721386A JP9383880A JP9383880A JPS5721386A JP S5721386 A JPS5721386 A JP S5721386A JP 9383880 A JP9383880 A JP 9383880A JP 9383880 A JP9383880 A JP 9383880A JP S5721386 A JPS5721386 A JP S5721386A
Authority
JP
Japan
Prior art keywords
compound
formula
alkyl
reaction product
oxazolidinone derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9383880A
Other languages
Japanese (ja)
Inventor
Yoshinori Tsuda
Kiyonori Yokogoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PAAMAKEMU ASIA KK
Permachem Asia Ltd
Original Assignee
PAAMAKEMU ASIA KK
Permachem Asia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PAAMAKEMU ASIA KK, Permachem Asia Ltd filed Critical PAAMAKEMU ASIA KK
Priority to JP9383880A priority Critical patent/JPS5721386A/en
Publication of JPS5721386A publication Critical patent/JPS5721386A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

PURPOSE: To obtain an oxazolidinone derivative useful as a synthetic intermediate for medicines in high yield, by reacting specific compounds, and reducing the reaction product.
CONSTITUTION: A compound of formula II (R is alkyl) is reacted with a compound of formula III (R1 and R2 are alkyl, aryl or aralkyl; two R2s may link to form an alkylene) in the presence of a solvent, e.g. a hydrocarbon, at a temperature of the boiling point of the reaction mixture of below for several hours to 24hr, and the reaction product is then reduced catalytically or with a reducing agent by the conventional method to give the aimed compound of formula I.
USE: 4-(2-Hydroxy-3-alkylaminopropoxy)indole obtained by hydrolyzing the aimed compound has β-adrenergic neuroplegic action and is useful for the remedy and the prevention of arrhythmia, etc.
COPYRIGHT: (C)1982,JPO&Japio
JP9383880A 1980-07-11 1980-07-11 Preparation of oxazolidinone derivative Pending JPS5721386A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9383880A JPS5721386A (en) 1980-07-11 1980-07-11 Preparation of oxazolidinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9383880A JPS5721386A (en) 1980-07-11 1980-07-11 Preparation of oxazolidinone derivative

Publications (1)

Publication Number Publication Date
JPS5721386A true JPS5721386A (en) 1982-02-04

Family

ID=14093525

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9383880A Pending JPS5721386A (en) 1980-07-11 1980-07-11 Preparation of oxazolidinone derivative

Country Status (1)

Country Link
JP (1) JPS5721386A (en)

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