JPS5721386A - Preparation of oxazolidinone derivative - Google Patents
Preparation of oxazolidinone derivativeInfo
- Publication number
- JPS5721386A JPS5721386A JP9383880A JP9383880A JPS5721386A JP S5721386 A JPS5721386 A JP S5721386A JP 9383880 A JP9383880 A JP 9383880A JP 9383880 A JP9383880 A JP 9383880A JP S5721386 A JPS5721386 A JP S5721386A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- alkyl
- reaction product
- oxazolidinone derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
PURPOSE: To obtain an oxazolidinone derivative useful as a synthetic intermediate for medicines in high yield, by reacting specific compounds, and reducing the reaction product.
CONSTITUTION: A compound of formula II (R is alkyl) is reacted with a compound of formula III (R1 and R2 are alkyl, aryl or aralkyl; two R2s may link to form an alkylene) in the presence of a solvent, e.g. a hydrocarbon, at a temperature of the boiling point of the reaction mixture of below for several hours to 24hr, and the reaction product is then reduced catalytically or with a reducing agent by the conventional method to give the aimed compound of formula I.
USE: 4-(2-Hydroxy-3-alkylaminopropoxy)indole obtained by hydrolyzing the aimed compound has β-adrenergic neuroplegic action and is useful for the remedy and the prevention of arrhythmia, etc.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9383880A JPS5721386A (en) | 1980-07-11 | 1980-07-11 | Preparation of oxazolidinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9383880A JPS5721386A (en) | 1980-07-11 | 1980-07-11 | Preparation of oxazolidinone derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5721386A true JPS5721386A (en) | 1982-02-04 |
Family
ID=14093525
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9383880A Pending JPS5721386A (en) | 1980-07-11 | 1980-07-11 | Preparation of oxazolidinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5721386A (en) |
-
1980
- 1980-07-11 JP JP9383880A patent/JPS5721386A/en active Pending
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