ES2058124T3 - Aerosoles que contienen liposomas y metodo para su preparacion. - Google Patents

Aerosoles que contienen liposomas y metodo para su preparacion.

Info

Publication number
ES2058124T3
ES2058124T3 ES87309854T ES87309854T ES2058124T3 ES 2058124 T3 ES2058124 T3 ES 2058124T3 ES 87309854 T ES87309854 T ES 87309854T ES 87309854 T ES87309854 T ES 87309854T ES 2058124 T3 ES2058124 T3 ES 2058124T3
Authority
ES
Spain
Prior art keywords
preparation
liposome
containing liposomes
aerosols containing
small particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87309854T
Other languages
English (en)
Inventor
Jack Vernon Knight
Brian E Gilbert
Samuel Z Wilson
Howard R Six
Philip R Wyde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Development Foundation
Original Assignee
Research Development Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Development Foundation filed Critical Research Development Foundation
Application granted granted Critical
Publication of ES2058124T3 publication Critical patent/ES2058124T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measurement Of Force In General (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

SE DESCRIBEN COMBINACIONES DE LIPOSOMA AEROSOL DE PEQUEÑAS PARTICULAS Y DE LIPOSOMA-MEDICAMENTO PROVECHOSAS PARA TRATAMIENTO DE UNA AMPLIA VARIEDAD DE ENFERMEDADES. SE DESCRIBEN DIFERENTES METODOS DE PREPARACION DE COMBINACIONES DE LIPOSOMA Y LIPOSOMA-MEDICAMENTO, QUE SE PUEDEN UTILIZAR EN EL TRATAMIENTO CON AEROSOL DE PARTICULAS PEQUEÑAS.
ES87309854T 1986-11-06 1987-11-06 Aerosoles que contienen liposomas y metodo para su preparacion. Expired - Lifetime ES2058124T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92789886A 1986-11-06 1986-11-06

Publications (1)

Publication Number Publication Date
ES2058124T3 true ES2058124T3 (es) 1994-11-01

Family

ID=25455423

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87309854T Expired - Lifetime ES2058124T3 (es) 1986-11-06 1987-11-06 Aerosoles que contienen liposomas y metodo para su preparacion.

Country Status (16)

Country Link
EP (1) EP0267050B1 (es)
JP (1) JP2933931B2 (es)
KR (1) KR910004580B1 (es)
AT (1) ATE111352T1 (es)
AU (1) AU600766B2 (es)
CA (1) CA1263310A (es)
DE (1) DE3750537T2 (es)
DK (1) DK582487A (es)
ES (1) ES2058124T3 (es)
FI (1) FI874895A (es)
HK (1) HK1006679A1 (es)
IE (1) IE63869B1 (es)
IL (1) IL84360A (es)
NO (1) NO874600L (es)
NZ (1) NZ222433A (es)
PT (1) PT86090B (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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AU614527B2 (en) * 1987-07-24 1991-09-05 Nexstar Pharmaceuticals, Inc. Opioid analgesic liposomal delivery-release system
JPH03501253A (ja) * 1987-09-22 1991-03-22 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア エイズ（ａｉｄｓ）治療を目的とするリポソームによるヌクレオシド類似物質
US5028697A (en) * 1988-08-08 1991-07-02 Eli Lilly And Company Cytotoxic antibody conjugates of hydrazide derivatized methotrexate analogs via simple organic linkers
IT1240353B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci immunomodulatori per applicazionelocale ed aerosolica
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
US5958379A (en) * 1994-09-30 1999-09-28 Mika Pharma Gesellschaft Fuer Die Entwicklung Und Vermarktung Pharmazeutischer Producte Mbh Pharmaceutical composition
US5891465A (en) * 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
TW497974B (en) * 1996-07-03 2002-08-11 Res Dev Foundation High dose liposomal aerosol formulations
ZA9711732B (en) 1996-12-31 1998-12-28 Quadrant Holdings Cambridge Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery
US20010055610A1 (en) * 1997-06-06 2001-12-27 Shunji Nagata Medicament administration system
EP1080720A4 (en) * 1998-03-05 2002-06-05 Nippon Shinyaku Co Ltd FAT EMULSIONS FOR INHALATIVE ADMINISTRATION
US6251425B1 (en) 1998-10-02 2001-06-26 Igen, Inc. Glucoside paucilamellar vesicles
CA2371689C (en) 1999-05-27 2012-06-26 Wolfgang Fleischer Preparations for the application of anti-infective and/or anti-inflammatory agents to external or internal parts of the human or animal body in functional and cosmetic tissue remodelling and repair treatment
EP1180018B1 (en) * 1999-05-27 2005-03-02 Euro-Celtique S.A. Use of antiseptics in the manufacture of a pharmaceutical preparation for the prevention and treatment of infections and/ or functional tissue remodelling in the interior of the human body
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
US6576224B1 (en) 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
NZ523693A (en) * 2000-07-10 2004-08-27 Chiron Corp Macrolide formulations for inhalation and methods of treatment of endobronchial infections
NZ532427A (en) 2001-09-24 2008-07-31 Imp Innovations Ltd Modification of feeding behavior using PYY (peptide YY) and its agonists such as NPY (neuropeptide Y)
US8058233B2 (en) 2002-01-10 2011-11-15 Oregon Health And Science University Modification of feeding behavior using PYY and GLP-1
EA008775B1 (ru) 2002-04-26 2007-08-31 Джилид Сайэнс, Инк. Ингибиторы протеазы вич для лечения инфекции вич и фармацевтическая композиция
GB0300571D0 (en) 2003-01-10 2003-02-12 Imp College Innovations Ltd Modification of feeding behaviour
WO2004096287A2 (en) 2003-04-25 2004-11-11 Gilead Sciences, Inc. Inosine monophosphate dehydrogenase inhibitory phosphonate compounds
US7452901B2 (en) 2003-04-25 2008-11-18 Gilead Sciences, Inc. Anti-cancer phosphonate analogs
US7470724B2 (en) 2003-04-25 2008-12-30 Gilead Sciences, Inc. Phosphonate compounds having immuno-modulatory activity
US7432261B2 (en) 2003-04-25 2008-10-07 Gilead Sciences, Inc. Anti-inflammatory phosphonate compounds
WO2005002626A2 (en) 2003-04-25 2005-01-13 Gilead Sciences, Inc. Therapeutic phosphonate compounds
US7407965B2 (en) 2003-04-25 2008-08-05 Gilead Sciences, Inc. Phosphonate analogs for treating metabolic diseases
US7300924B2 (en) 2003-04-25 2007-11-27 Gilead Sciences, Inc. Anti-infective phosphonate analogs
JP2006524710A (ja) 2003-04-25 2006-11-02 ギリアード サイエンシーズ， インコーポレイテッド キナーゼインヒビターホスホネート抱合体
DK1628685T3 (da) 2003-04-25 2011-03-21 Gilead Sciences Inc Antivirale phosphonatanaloge
WO2005044308A1 (en) * 2003-10-24 2005-05-19 Gilead Sciences, Inc. Phosphonate analogs of antimetabolites
WO2005044279A1 (en) 2003-10-24 2005-05-19 Gilead Sciences, Inc. Purine nucleoside phosphonate conjugates
JP2007508843A (ja) 2003-10-24 2007-04-12 ギリアード サイエンシーズ， インコーポレイテッド 治療用化合物の同定のための方法および組成物
MXPA06006899A (es) 2003-12-22 2006-09-04 Gilead Sciences Inc Derivados de carbovir y abacavir 4'-sustituidos asi como compuestos relacionados con actividad antiviral de virus de inmunodeficiencia humana y virus de la hepatitis c.
US7871991B2 (en) 2004-07-27 2011-01-18 Gilead Sciences, Inc. Phosphonate analogs of HIV inhibitor compounds
TWI428346B (zh) 2006-12-13 2014-03-01 Imp Innovations Ltd 新穎化合物及其等對進食行為影響
US10251839B2 (en) 2008-01-22 2019-04-09 Igi Laboratories, Inc. Lipid vesicles derived from olive oil fatty acids
WO2009143011A1 (en) * 2008-05-20 2009-11-26 Novartis Ag Antiviral compositions, methods of making and using such compositions, and systems for pulmonary delivery of such compositions
MX2011000306A (es) 2008-07-08 2011-03-15 Gilead Sciences Inc Sales de compuestos inhibidores de hiv.
EP3960740B1 (en) 2017-08-01 2023-11-15 Gilead Sciences, Inc. Crystalline forms of ethyl ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate (gs-9131) vanillate for treating viral infections
JP7391039B2 (ja) 2018-04-23 2023-12-04 インスパーメッド コーポレーション 肺疾患の処置に使用するための吸入可能なリポソーム徐放性組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594476A (en) * 1969-05-12 1971-07-20 Massachusetts Inst Technology Submicron aqueous aerosols containing lecithin
FR2543018B1 (fr) * 1983-03-22 1985-07-26 Oreal Procede de preparation de vesicules lipidiques par vaporisation de solvants
GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions
EP0158441B2 (en) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposome-forming composition
EP0172007B1 (en) * 1984-08-10 1991-05-22 Syntex (U.S.A.) Inc. Stable liposomes with aqueous-soluble medicaments and methods for their preparation
GB8423436D0 (en) * 1984-09-17 1984-10-24 Riker Laboratories Inc Preparation of liposomes
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
GB8502892D0 (en) * 1985-02-05 1985-03-06 Sterwin Ag Aerosol composition
WO1986006959A1 (en) * 1985-05-22 1986-12-04 Liposome Technology, Inc. Liposome inhalation method and system
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol

Also Published As

Publication number Publication date
CA1263310A (en) 1989-11-28
EP0267050A3 (en) 1988-10-26
DK582487A (da) 1988-05-07
KR880005921A (ko) 1988-07-21
NO874600L (no) 1988-05-09
NZ222433A (en) 1990-09-26
EP0267050A2 (en) 1988-05-11
NO874600D0 (no) 1987-11-04
IL84360A0 (en) 1988-04-29
PT86090A (en) 1987-12-01
IE872938L (en) 1988-05-06
PT86090B (pt) 1990-11-20
ATE111352T1 (de) 1994-09-15
DE3750537T2 (de) 1995-01-12
AU600766B2 (en) 1990-08-23
IE63869B1 (en) 1995-06-14
JPS63211223A (ja) 1988-09-02
IL84360A (en) 1992-01-15
HK1006679A1 (en) 1999-03-12
FI874895A0 (fi) 1987-11-05
KR910004580B1 (ko) 1991-07-06
JP2933931B2 (ja) 1999-08-16
DE3750537D1 (de) 1994-10-20
AU8081987A (en) 1988-06-02
EP0267050B1 (en) 1994-09-14
FI874895A (fi) 1988-05-07
DK582487D0 (da) 1987-11-05

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